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Total 45 results found since Jan 2013.

Quality in Acute Stroke Care (QASC): process evaluation of an intervention to improve the management of fever, hyperglycemia, and swallowing dysfunction following acute stroke
BackgroundOur randomized controlled trial of a multifaceted evidence‐based intervention for improving the inpatient management of fever, hyperglycemia, and swallowing dysfunction in the first three‐days following stroke improved outcomes at 90 days by 15%. We designed a quantitative process evaluation to further explain and illuminate this finding. MethodsBlinded retrospective medical record audits were undertaken for patients from 19 stroke units prior to and following the implementation of three multidisciplinary evidence‐based protocols (supported by team‐building workshops, and site‐based education and suppor...
Source: International Journal of Stroke - December 1, 2013 Category: Neurology Authors: Peta Drury, Christopher Levi, Catherine D'Este, Patrick McElduff, Elizabeth McInnes, Jennifer Hardy, Simeon Dale, N Wah Cheung, Jeremy M Grimshaw, Clare Quinn, Jeanette Ward, Malcolm Evans, Dominique Cadilhac, Rhonda Griffiths, Sandy Middleton Tags: Research Source Type: research

Age- and Sex-Associated Impacts of Body Mass Index on Stroke Type Risk: A 27-Year Prospective Cohort Study in a Low-Income Population in China
Conclusions Being overweight increased the risk of both ischemic and hemorrhagic strokes; obesity was only associated with an increased risk of IS. Additionally, the positive association between BMI and stroke risk was only observed in participants aged <65 years and the associations differed between men and women. Being overweight increased the risk of both ischemic and hemorrhagic strokes in men and being underweight increased their risk of hemorrhagic stroke. In women, being overweight increased the hemorrhagic stroke risk, whereas obesity increased their IS risks. The high prevalence of hypertension and elevat...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

The Paradoxical Protective Effect of Liver Steatosis on Severity and Functional Outcome of Ischemic Stroke
Conclusions: Our study shows that a higher burden of liver steatosis seems to be associated with less severe stroke and better functional outcome after ischemic stroke or TIA. Introduction Non-alcoholic fatty liver disease (NAFLD) is a spectrum of diseases from simple steatosis to steatohepatitis with varying degree of fibrosis, and liver cirrhosis (1, 2). NAFLD is becoming the most common chronic liver disease worldwide including Korea, affecting approximately 25% of the general population (3, 4). NAFLD is closely associated with obesity, insulin resistance, and type 2 diabetes mellitus, and is even recognized as ...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Stroke risk in treatment of type 2 diabetes in China: a 7 year retrospective cohort study
Publication date: November 2016 Source:The Lancet Diabetes &amp; Endocrinology, Volume 4, Supplement 1 Author(s): Rui Liu, Qing Wang, Vivian Szeto, Andrew Barszczyk, Tianru Jin, Edoardo Mannucci, Hong-Shuo Sun, Zhong-Ping Feng Background Diabetes and stroke are leading causes of death and disability, and major public health concerns in China, which accounts for 25% of patients with diabetes worldwide. Type 2 diabetes is an independent risk factor for cerebral ischaemia and accounts for about 20% of stroke cases. We previously showed that KATP channel activation provides neuroprotection against cerebral ischaemia and t...
Source: The Lancet Diabetes and Endocrinology - November 17, 2016 Category: Endocrinology Source Type: research

European Academy of Neurology – European Stroke Organisation consensus statement and practical guidance for pre‐hospital management of stroke
This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - December 7, 2017 Category: Neurology Authors: A. Kobayashi, A. Czlonkowska, G.A. Ford, A.C. Fonseca, G.J. Luijckx, J. Korv, N. P érez de la Ossa, C. Price, D. Russell, A. Tsiskaridze, M. Messmer‐Wullen, J. De Keyser Tags: Guidelines Source Type: research

European Academy of Neurology and European Stroke Organization consensus statement and practical guidance for pre ‐hospital management of stroke
ConclusionsThese guidelines inform on the contemporary approach to patients with suspected stroke in the pre‐hospital setting. Further studies, preferably randomized controlled trials, are required to examine the impact of particular interventions on quality parameters and outcome.
Source: European Journal of Neurology - January 12, 2018 Category: Neurology Authors: A. Kobayashi, A. Czlonkowska, G. A. Ford, A. C. Fonseca, G. J. Luijckx, J. Korv, N. P érez Ossa, C. Price, D. Russell, A. Tsiskaridze, M. Messmer‐Wullen, J. De Keyser Tags: Guideline Source Type: research

Barriers and Enablers to Implementing Clinical Treatment Protocols for Fever, Hyperglycaemia, and Swallowing Dysfunction in the Quality in Acute Stroke Care (QASC) Project—A Mixed Methods Study
ABSTRACT BackgroundThe Quality in Acute Stroke Care (QASC) trial evaluated systematic implementation of clinical treatment protocols to manage fever, sugar, and swallow (FeSS protocols) in acute stroke care. This cluster‐randomised controlled trial was conducted in 19 stroke units in Australia. AimTo describe perceived barriers and enablers preimplementation to the introduction of the FeSS protocols and, postimplementation, to determine which of these barriers eventuated as actual barriers. MethodsPreimplementation: Workshops were held at the intervention stroke units (n = 10). The first workshop involved senior clinicia...
Source: Worldviews on Evidence-Based Nursing - December 1, 2014 Category: Nursing Authors: Simeon Dale, Christopher Levi, Jeanette Ward, Jeremy M. Grimshaw, Asmara Jammali‐Blasi, Catherine D'Este, Rhonda Griffiths, Clare Quinn, Malcolm Evans, Dominique Cadilhac, N. Wah Cheung, Sandy Middleton Tags: Original Article Source Type: research

The Relationship between Glucose Control & Cognitive Function in People with Diabetes after a Lacunar Stroke.
CONCLUSION: This analysis of lacunar stroke patients with diabetes demonstrates a relationship between A1C and change in cognitive scores over time. Intervention studies are needed in order to delineate if better glucose control could slow the rate of cognitive decline in this high risk population. PMID: 33481011 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - January 22, 2021 Category: Endocrinology Authors: Cukierman-Yaffe T, McClure LA, Thomas R, Bosch J, Sharma M, Gerstein HC, Benavente O Tags: J Clin Endocrinol Metab Source Type: research

Atherosclerotic Cardiovascular Disease in South Asians in the United States: Epidemiology, Risk Factors, and Treatments: A Scientific Statement From the American Heart Association.
cial Populations Committee of the Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Quality of Care and Outcomes Research; and Stroke Council Abstract South Asians (from Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri Lanka) make up one quarter of the world's population and are one of the fastest-growing ethnic groups in the United States. Although native South Asians share genetic and cultural risk factors with South Asians abroad, South Asians in the United States can differ in socioeconomic status, education, healthcare behaviors, attitudes, and health in...
Source: Circulation - May 24, 2018 Category: Cardiology Authors: Volgman AS, Palaniappan LS, Aggarwal NT, Gupta M, Khandelwal A, Krishnan AV, Lichtman JH, Mehta LS, Patel HN, Shah KS, Shah SH, Watson KE, American Heart Association Council on Epidemiology and Prevention; Cardiovascular Disease and Stroke in Women and Sp Tags: Circulation Source Type: research

Metformin associated with better cardiovascular outcomes than other glycaemic therapies
Context A question exists as to whether the outcome of glycaemic treatment of diabetes varies with the agent used; speculation surrounds whether metformin might be preferable to other treatments. Methods Ghotbi and colleagues performed an epidemiological analysis of 8192 obese patients with diabetes at increased cardiovascular risk participating in the Sibutramine Cardiovascular OUTcomes (SCOUT) trial. Mortality and a combined cardiovascular outcome of non-fatal myocardial infarction, non-fatal stroke, resuscitation after cardiac arrest or cardiovascular death were compared among those receiving one of the following interv...
Source: Evidence-Based Medicine - May 19, 2014 Category: Internal Medicine Authors: Bloomgarden, Z. T. Tags: Smoking and tobacco, Epidemiologic studies, Drugs: cardiovascular system, Heart failure, Stroke, Hypertension, Diet, Obesity (nutrition), Ischaemic heart disease, Diabetes, Health education, Smoking Therapeutics Source Type: research

Correlation Between Intracranial Arterial Calcification and Imaging of Cerebral Small Vessel Disease
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Can DIY and gardening help you live longer?
Conclusion This study found that in a population-based sample of older adults (aged 60), high levels of non-exercise physical activity, or ‘an active daily life’ was associated with better levels of cardiovascular risk factors. When followed over time, it was found an active daily life was associated with approximately 30% reduced risk of both a cardiovascular event (stroke, angina, heart attack) and death from any cause. These associations were seen after adjusting for regular exercise, and for a number of other factors that could explain the association seen (confounders). This study was a cross-sectional and cohort...
Source: NHS News Feed - October 29, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Heart/lungs Source Type: news

Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease
CONCLUSIONS Among patients with insulin resistance but without diabetes who had had a recent ischemic stroke or TIA, pioglitazone decreased the risk of diabetes while also reducing the risk of subsequent ischemic events. Pioglitazone is the first medication shown to prevent both progression to diabetes and major cardiovascular events as prespecified outcomes in a single trial.
Source: Diabetes Care - September 21, 2016 Category: Endocrinology Authors: Inzucchi, S. E.; Viscoli, C. M.; Young, L. H.; Furie, K. L.; Gorman, M.; Lovejoy, A. M.; Dagogo-Jack, S.; Ismail-Beigi, F.; Korytkowski, M. T.; Pratley, R. E.; Schwartz, G. G.; Kernan, W. N.; for the IRIS Trial Investigators Tags: Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research

Can sleeping too much cause chronic diseases?
Conclusion This 2010 survey data from middle aged and older adults from 14 US states suggests an association between shorter and longer than optimal sleep duration and three chronic diseases. The optimal amount of sleep recommended varies by different organisations, but tends to be either seven to eight or seven to nine hours a night for an adult. However, though the study benefits from its large sample size of over 50,000 adults it has significant limitations. Cross sectional study design Most importantly, the cross sectional study design which has assessed sleep duration and disease presence at the same time cannot prov...
Source: NHS News Feed - October 4, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Heart/lungs Diabetes Source Type: news

Long-Term Exposure to Road Traffic Noise and Nitrogen Dioxide and Risk of Heart Failure: A Cohort Study
Conclusions: Long-term exposure to NO2 and road traffic noise was associated with higher risk of heart failure, mainly among men, in both single- and two-pollutant models. High exposure to both pollutants was associated with highest risk. https://doi.org/10.1289/EHP1272 Received: 25 October 2016 Revised: 09 August 2017 Accepted: 09 August 2017 Published: 26 September 2017 Address correspondence to M. Sørensen. Diet, Genes and Environment, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark. Telephone: +45 35257626. Email: mettes@cancer.dk Supplemental Material is available online (https://doi.org/1...
Source: EHP Research - September 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research