Age- and Sex-Associated Impacts of Body Mass Index on Stroke Type Risk: A 27-Year Prospective Cohort Study in a Low-Income Population in China
Conclusions
Being overweight increased the risk of both ischemic and hemorrhagic strokes; obesity was only associated with an increased risk of IS. Additionally, the positive association between BMI and stroke risk was only observed in participants aged <65 years and the associations differed between men and women. Being overweight increased the risk of both ischemic and hemorrhagic strokes in men and being underweight increased their risk of hemorrhagic stroke. In women, being overweight increased the hemorrhagic stroke risk, whereas obesity increased their IS risks. The high prevalence of hypertension and elevated BP levels in this low-income population may partially explain the observed positive association between BMI and stroke risk. These findings suggest that weight management should be a high priority for substantially reducing the heavy burden of strokes in rural China, among both men and women aged <65 years; men should maintain their weight within a reasonable range.
Ethics Statement
This study was carried out in accordance with the recommendations of the ethics committee of Tianjin Medical University General Hospital with written informed consent from all subjects. All subjects gave written informed consent in accordance with the Declaration of Helsinki.
Author Contributions
JW, BL, and YL contributed to the conception and design of the work. HG, SS, JL, ZF, YC, JN, CW, and JT contributed the data acquisition. JW and XN contributed the analysi...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
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