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Condition: Diabetes Mellitus
Drug: Insulin

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Total 394 results found since Jan 2013.

Effects and Mechanistic Role of Mulberry Leaves in Treating Diabetes and its Complications
Am J Chin Med. 2023 Aug 30:1-39. doi: 10.1142/S0192415X23500775. Online ahead of print.ABSTRACTDiabetes mellitus (DM) has become a surge burden worldwide owing to its high prevalence and range of associated complications such as coronary artery disease, blindness, stroke, and renal failure. Accordingly, the treatment and management of DM have become a research hotspot. Mulberry leaves (Morus alba L.) have been used in Traditional Chinese Medicine for a long time, with the first record of its use published in Shennong Bencao Jing (Shennong's Classic of Materia Medica). Mulberry leaves (MLs) are considered highly valuable me...
Source: The American Journal of Chinese Medicine - August 30, 2023 Category: Complementary Medicine Authors: Yanjiao Zhang Runyu Miao Kaile Ma Yuxin Zhang Xinyi Fang Jiahua Wei Ruiyang Yin Jingxue Zhao Jiaxing Tian Source Type: research

Investigation of Pancreatic-beta cells Role in the Biological Process of Ageing
CONCLUSION: Aging accelerates beta cell senescence by generating premature cell senescence, which is mostly mediated by high glucose levels. Despite higher plasma glucose levels, hepatic gluconeogenesis accelerates and adipose tissue lipolysis rises, resulting in an increase in free fatty acid levels in the blood and worsening insulin resistance throughout the body.PMID:37608675 | DOI:10.2174/1871530323666230822095932
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 23, 2023 Category: Endocrinology Authors: Rishabh Chaudhary Janvi Khanna Manni Rohilla Sumeet Gupta Seema Bansal Source Type: research

Role of GLP-1 receptor agonist in diabetic cardio-renal disorder: Recent updates of clinical and pre-clinical evidence
Curr Diabetes Rev. 2023 Aug 9. doi: 10.2174/1573399820666230809152148. Online ahead of print.ABSTRACTCardiovascular complications and renal disease is the growing cause of mortality in patients with diabetes. The subversive complications of diabetes such as hyperglycemia, hyperlipidemia and insulin resistance lead to an increase in the risk of myocardial infarction (MI), stroke, heart failure (HF) as well as chronic kidney disease (CKD). Among the commercially available anti-hyperglycemic agents, incretin-based medications appear to be safe and effective in the treatment of type 2 diabetes mellitus (T2DM) and associated ca...
Source: Current Diabetes Reviews - August 10, 2023 Category: Endocrinology Authors: Sanket Seksaria Bhaskar Jyoti Dutta Mandeep Kaur Ghanshyam Das Gupta Surendra H Bodakhe Amrita Singh Source Type: research

How do patients with Type 2 Diabetes Mellitus value the importance of outcomes? An overview of reviews
CONCLUSION: We provide standardised, reliable utility values (or associated disutilities) for T2DM, acute, microvascular and macrovascular complications, related comorbidities and treatments that may support judgements when making clinical recommendations, designing decision support tools, and developing interventions and economic analysis.PMID:37516195 | DOI:10.1016/j.jval.2023.07.003
Source: Cancer Control - July 29, 2023 Category: Cancer & Oncology Authors: Ena Nino-de-Guzman Javier Bracchiglione Adrian Vasquez-Mejia Gimon de Graaf Claudio Rocha Calderon Pablo Alonso-Coello Source Type: research

Do Non-Functional Adrenal Adenomas Affect Metabolic Profile and Carotid Intima-Media Thickness? A Single Centre Study from Poland
Conclusions: Patients diagnosed with NFAIs, despite normal cortisol inhibition in the 1 mg dexamethasone test, still presented a number of metabolic abnormalities. The assessment of IMT may proove valuable in indicate the presence of early vascular remodelling in asymptomatic patients. The underlying mechanisms of these findings are still unknown, hence further studies are required.PMID:37510727 | PMC:PMC10380859 | DOI:10.3390/jcm12144612
Source: Atherosclerosis - July 29, 2023 Category: Cardiology Authors: Magdalena Szychli ńska Magdalena Rzeczkowska Katarzyna Gontarz-Nowak Wojciech Matuszewski El żbieta Bandurska-Stankiewicz Source Type: research

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes syndrome: a case report from Nepal
Ann Med Surg (Lond). 2023 May 3;85(6):3026-3030. doi: 10.1097/MS9.0000000000000712. eCollection 2023 Jun.ABSTRACTMitochondrial encephalomyopathy, lactic acidosis, and stroke-like syndrome (MELAS) is a rare neurodegenerative inherited disorder that is characterized by stroke-like episodes, seizures, endocrine, and multiple system involvement. It is important to consider it as a differential diagnosis in a young patient with stroke-like episodes as it is progressive and has multiple complications.CASE PRESENTATION: A 28-year-old male presented with slurring of speech and drowsiness for 7 h. He was a diagnosed case of type 2 ...
Source: Annals of Medicine - June 26, 2023 Category: Internal Medicine Authors: Ram C Subedi Raju Paudel Sharma Paudel Lekhjung Thapa Subash Phuyal Naresh Kharbuja Ayush Adhikari Source Type: research

Diabetes mellitus and adverse outcomes after carotid endarterectomy: A systematic review and meta-analysis
CONCLUSIONS: In patients with carotid stenosis treated by CEA, DM is associated with short-term and long-term MAEs. DM may have a greater impact on adverse outcomes in asymptomatic patients after CEA. Insulin-dependent DM may have a more significant impact on post-CEA adverse outcomes than noninsulin-dependent DM. Whether DM management could reduce the risk of adverse outcomes after CEA requires further investigation.PMID:37334731 | PMC:PMC10278750 | DOI:10.1097/CM9.0000000000002730
Source: Chinese Medical Journal - June 19, 2023 Category: General Medicine Authors: Fengshi Li Rui Zhang Xiao Di Shuai Niu Zhihua Rong Changwei Liu Leng Ni Source Type: research

The Link between Magnesium Supplements and Statin Medication in Dyslipidemic Patients
Curr Issues Mol Biol. 2023 Apr 5;45(4):3146-3167. doi: 10.3390/cimb45040205.ABSTRACTMany investigations have discovered a connection between statins and magnesium supplements. On one hand, increasing research suggests that chronic hypomagnesemia may be an important factor in the etiology of some metabolic illnesses, including obesity and overweight, insulin resistance and type 2 diabetes mellitus, hypertension, alterations in lipid metabolism, and low-grade inflammation. Chronic metabolic problems seem to be prevented by a high Mg intake combined with diet and/or supplements. On the other hand, it is known that statins low...
Source: Mol Biol Cell - May 15, 2023 Category: Molecular Biology Authors: Roxana Nartea Brindusa Ilinca Mitoiu Ioana Ghiorghiu Source Type: research