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How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you… Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China. I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1 We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004. Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news

Steady solution and its stability of a mathematical model of diabetic atherosclerosis
J Biol Dyn. 2023 Dec;17(1):2257734. doi: 10.1080/17513758.2023.2257734.ABSTRACTAtherosclerosis is a leading cause of death worldwide. Making matters worse, nearly 463 million people have diabetes, which increases atherosclerosis-related inflammation. Diabetic patients are twice as likely to have a heart attack or stroke. In this paper, we consider a simplified mathematical model for diabetic atherosclerosis involving LDL, HDL, glucose, insulin, free radicals (ROS), β cells, macrophages and foam cells, which satisfy a system of partial differential equations with a free boundary, the interface between the blood flow and th...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Xuming Xie Source Type: research

Potentially Inappropriate Medication Use Among Older Patients with Diabetes in a Chinese Community
Conclusions Given the higher rate of PIM use among older adults with diabetes, strategies and interventions targeting this population are needed to minimize PIM use. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Experimental and Clinical Endocrinology and Diabetes - September 6, 2023 Category: Endocrinology Authors: Zhao, Xingxing Li, Lei Guo, Xiujun Wang, Jianqiang Yan, Yingying Le, Yunyi Tags: Article Source Type: research

Glutamate infusion reduces myocardial dysfunction after coronary artery bypass grafting according to NT-proBNP: summary of two randomized controlled trials (GLUTAMICS I-II)
CONCLUSIONS: Infusion of glutamate reduced postoperative rise in NT-proBNP after CABG in medium to high-risk patients. A significantly blunted effect was observed only in insulin-treated diabetes patients.CLINICAL TRIAL REGISTRATION: NCT02592824, https://clinicaltrials.gov/ct2/show/NCT02592824.PMID:37657522 | DOI:10.1016/j.ajcnut.2023.08.012
Source: The American Journal of Clinical Nutrition - September 1, 2023 Category: Nutrition Authors: Jonas Holm Farkas Vanky Rolf Svedjeholm Source Type: research

Effects and Mechanistic Role of Mulberry Leaves in Treating Diabetes and its Complications
Am J Chin Med. 2023 Aug 30:1-39. doi: 10.1142/S0192415X23500775. Online ahead of print.ABSTRACTDiabetes mellitus (DM) has become a surge burden worldwide owing to its high prevalence and range of associated complications such as coronary artery disease, blindness, stroke, and renal failure. Accordingly, the treatment and management of DM have become a research hotspot. Mulberry leaves (Morus alba L.) have been used in Traditional Chinese Medicine for a long time, with the first record of its use published in Shennong Bencao Jing (Shennong's Classic of Materia Medica). Mulberry leaves (MLs) are considered highly valuable me...
Source: The American Journal of Chinese Medicine - August 30, 2023 Category: Complementary Medicine Authors: Yanjiao Zhang Runyu Miao Kaile Ma Yuxin Zhang Xinyi Fang Jiahua Wei Ruiyang Yin Jingxue Zhao Jiaxing Tian Source Type: research

Insulin resistance estimated by estimated glucose disposal rate predicts outcomes in acute ischemic stroke patients
In this study, we...
Source: Cardiovascular Diabetology - August 26, 2023 Category: Cardiology Authors: Zhengzhao Lu, Yunyun Xiong, Xueyan Feng, Kaixuan Yang, Hongqiu Gu, Xingquan Zhao, Xia Meng and Yongjun Wang Tags: Research Source Type: research

Can This Breakfast Food Reverse Alzheimer ’ s?
I’m sure you’ve noticed how expensive eggs have gotten lately. The price has soared more than any other food in the supermarket…up 60% from one year ago.1 One reason for skyrocketing prices is the ongoing avian flu epidemic. But another reason is that demand for “nature’s perfect food” has increased substantially. And that is good news because eggs are essential for your health – including the fight against Alzheimer’s. And that means they’re worth every penny for the way they protect your brain. Two breakthrough studies back up what I’ve been telling my patients for over three decades… That ...
Source: Al Sears, MD Natural Remedies - August 25, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Brain Health Nutrition Source Type: news

Circular RNA ciRS-7 signature as a potential biomarker for the early detection of diabetes with Alzheimer's disease: a hypothesis
Mol Biol Rep. 2023 Aug 24. doi: 10.1007/s11033-023-08729-2. Online ahead of print.ABSTRACTIn the 1970s, Circular RNAs (CircRNAs) were first discovered in RNA viruses as viroids and were initially assumed to be RNA splicing defects. The roles and topologies of these circular RNA loops were later revealed using computer analysis and RNA-sequencing. They were found to demonstrate various functions, including protein scaffolding, parental gene regulation, microRNA sponges, and RNA-protein interactions. CircRNAs play a crucial role in controlling gene expression and are essential for biological development and illness detection...
Source: Molecular Biology Reports - August 24, 2023 Category: Molecular Biology Authors: Mahima Singh Ajay Guru Raghul Murugan Muthukaruppan Gopi Jesu Arockiaraj Source Type: research

Investigation of Pancreatic-beta cells Role in the Biological Process of Ageing
CONCLUSION: Aging accelerates beta cell senescence by generating premature cell senescence, which is mostly mediated by high glucose levels. Despite higher plasma glucose levels, hepatic gluconeogenesis accelerates and adipose tissue lipolysis rises, resulting in an increase in free fatty acid levels in the blood and worsening insulin resistance throughout the body.PMID:37608675 | DOI:10.2174/1871530323666230822095932
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 23, 2023 Category: Endocrinology Authors: Rishabh Chaudhary Janvi Khanna Manni Rohilla Sumeet Gupta Seema Bansal Source Type: research