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Total 3248 results found since Jan 2013.

National Trends, Risk Factors, and Outcomes of Acute In-hospital Stroke After Lung Transplantation in the United States: Analysis of the United Network for Organ Sharing Registry
Chest. 2023 Apr 11:S0012-3692(23)00503-2. doi: 10.1016/j.chest.2023.04.007. Online ahead of print.ABSTRACTBACKGROUND: Lung transplantation is the definitive treatment for end-stage lung failure. However, there have been no large, long-term studies on the impact of acute in-hospital stroke in this population.RESEARCH QUESTION: What are the trends, risk factors, and outcomes of acute stroke in patients undergoing lung transplantation in the United States?STUDY DESIGN AND METHODS: We identified adult first-time, isolated lung transplant (LTx) recipients from the United Network for Organ Sharing (UNOS) database, which comprehe...
Source: Chest - April 13, 2023 Category: Respiratory Medicine Authors: Benjamin L Shou Christopher Wilcox Isabella Florissi Aravind Krishnan Bo Soo Kim Steven P Keller Glenn J R Whitman Ken Uchino Errol L Bush Sung-Min Cho Source Type: research

Bibliometric analysis of stroke and quality of life
ConclusionA bibliometric analysis of stroke and quality of life over the last 23 years provides future research directions.
Source: Frontiers in Neurology - April 11, 2023 Category: Neurology Source Type: research

Mechanisms of in-hospital acute ischemic stroke and their relevance to prognosis: A retrospective analysis
In-hospital stroke (IHS) refers to stroke that occurs during hospitalization in patients admitted for other diagnoses,1 of which ischemic stroke is the most common type, accounting for approximately 60% to 89%.2,3 IHS is common with approximately 35,000 to 75,000 patients having a stroke while hospitalized in the United States each year.4 The incidence of IHS tends to increase per year,5 resulting in a serious social burden. In-hospital ischemic strokes are widely distributed across various in-hospital departments.
Source: Journal of Stroke and Cerebrovascular Diseases - April 11, 2023 Category: Neurology Authors: Juanjuan Wu, Guangsong Han, Yuhui Sha, Mingyu Tang, Ziang Pan, Ziyue Liu, Yicheng Zhu, Lixin Zhou, Jun Ni Source Type: research

Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines
AbstractPurpose of ReviewStroke is a leading cause of death and disability worldwide. The annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the United States, of which 87% are ischemic in nature. In addition to the management of modifiable high-risk factors to reduce the risk of recurrent stroke, antithrombotic agents (antiplatelets and anticoagulants) play an important role in secondary stroke prevention. This review will discuss the published literature on the use of antiplatelets and anticoagulants in secondary prevention of acute ischemic stroke and transient ischemic attack (TIA), ...
Source: Current Neurology and Neuroscience Reports - April 11, 2023 Category: Neuroscience Source Type: research

Cardiovascular Disease Risk Factors in Women: The Impact of Race and Ethnicity: A Scientific Statement From the American Heart Association
Circulation. 2023 Apr 10. doi: 10.1161/CIR.0000000000001139. Online ahead of print.ABSTRACTCardiovascular disease is the leading cause of death in women, yet differences exist among certain racial and ethnic groups. Aside from traditional risk factors, behavioral and environmental factors and social determinants of health affect cardiovascular health and risk in women. Language barriers, discrimination, acculturation, and health care access disproportionately affect women of underrepresented races and ethnicities. These factors result in a higher prevalence of cardiovascular disease and significant challenges in the diagno...
Source: Circulation - April 10, 2023 Category: Cardiology Authors: Laxmi S Mehta Gladys P Velarde Jennifer Lewey Garima Sharma Rachel M Bond Ana Navas-Acien Amanda M Fretts Gayenell S Magwood Eugene Yang Roger S Blumenthal Rachel-Maria Brown Jennifer H Mieres American Heart Association Cardiovascular Disease and Stroke i Source Type: research

Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines
Curr Neurol Neurosci Rep. 2023 Apr 11. doi: 10.1007/s11910-023-01266-2. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Stroke is a leading cause of death and disability worldwide. The annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the United States, of which 87% are ischemic in nature. In addition to the management of modifiable high-risk factors to reduce the risk of recurrent stroke, antithrombotic agents (antiplatelets and anticoagulants) play an important role in secondary stroke prevention. This review will discuss the published literature on the use of antiplatelets and antic...
Source: Atherosclerosis - April 10, 2023 Category: Cardiology Authors: Kunal Bhatia Lindsey M Ladd Kelsey H Carr Mario Di Napoli Jeffrey L Saver Louise D McCullough Maryam Hosseini Farahabadi Diana L Alsbrook Archana Hinduja Jorge G Ortiz Garcia Sara Y Sabbagh Alibay Jafarli Afshin A Divani Source Type: research

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Neurologic emergencies can be difficult to diagnose and treat, and are devastating if missed. Stroke is still the number five cause of death in the United States, down from number three a few years ago, and is the leading cause of long-term serious disability. Nonconvulsive status epilepticus is a substantial problem in intensive care units. Traumatic brain injuries from head trauma are a leading cause of post-traumatic stress in many populations. Then we have spine injuries, headache, back pain, infections, and vision problems, which present to emergency departments on a daily basis.
Source: The Journal of Emergency Medicine - April 5, 2023 Category: Emergency Medicine Authors: Edward J. Otten Tags: Book and Other Media Reviews Source Type: research

Cardiac transplant and exercise cardiac rehabilitation
AbstractCardiac transplantation is the final therapeutic option for patients with end-stage heart failure. Most patients experience a favorable functional ability post-transplant. However, episodes of acute rejection, and multiple comorbidities such as hypertension, diabetes mellitus, chronic kidney disease and cardiac allograft vasculopathy are common. The number of transplants has increased steadily over the past two decades with 3,817 operations performed in the United States in 2021. Patients have abnormal exercise physiologic responses related to surgical cardiac denervation, diastolic dysfunction, and the legacy of r...
Source: Heart Failure Reviews - April 4, 2023 Category: Cardiology Source Type: research

ERLEADA ® (apalutamide), First-and-Only Next-Generation Androgen Receptor Inhibitor with Once-Daily, Single-Tablet Option, Now Available in the U.S.
HORSHAM, Pa., April 3, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the availability of an additional tablet strength of ERLEADA® (apalutamide) in the United States. The introduction of the 240mg tablet provides the first-and-only option for a once-daily, single-tablet Androgen Receptor Inhibitor (ARI) approved for the treatment of patients with non-metastatic castration-resistant prostate cancer (nmCRPC) and for the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC).With two strengths available, healthcare professionals will have the flexibility to...
Source: Johnson and Johnson - April 3, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Global research trends on COVID-19 and stroke: A bibliometric analysis
ConclusionOur bibliometric analysis provides a comprehensive overview of the current state of research on COVID-19 and stroke and highlights key areas of focus in the field. Optimizing the treatment of COVID-19-infected stroke patients and elucidating the underlying pathogenic mechanisms of COVID-19 and stroke co-morbidity are key areas of future research that will be beneficial in improving the prognosis of stroke patients during the ongoing COVID-19 epidemic.
Source: Frontiers in Neurology - April 3, 2023 Category: Neurology Source Type: research

Incidence and Impact of Post-Transplant Stroke on Outcomes Following Orthotopic Heart Transplantation Under the 2018 United States Heart Allocation System: A UNOS Registry Analysis
With the increased rate of temporary mechanical circulatory support utilization after the 2018 heart allocation policy change, we sought to quantitate the clinical trends and impact of post-transplant stroke (PTS) and functional independence on outcomes following orthotopic heart transplant (OHT).
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: Y. Hong, L.V. Huckaby, N.R. Hess, L.A. Ziegler, G.W. Hickey, J.H. Huston, M.A. Mathier, D.M. McNamara, M.E. Keebler, D.J. Kaczorowski Tags: (639) Source Type: research

Vagus Nerve Stimulation Paired with Upper-Limb Rehabilitation After Stroke: Two- and Three-Year Follow-up from the Pilot Study
CONCLUSIONS: Significant effects of Paired VNS therapy at one year were maintained at years 2 and 3, and further improvements in both impairment and function were observed in years 2 and 3. These changes were associated with improvements in measures of activity and participation.PMID:37001842 | DOI:10.1016/j.apmr.2023.02.012
Source: Health Physics - March 31, 2023 Category: Physics Authors: Gerard E Francisco Navzer Engineer Jesse Dawson Teresa J Kimberley Steven Cramer Cec ília N Prudente David Pierce Brent W Tarver Reema H Adham Hinds Ann Van de Winckel Nuray Yozbatiran Source Type: research

Exploring the bi-directional relationship and shared genes between depression and stroke via NHANES and bioinformatic analysis
Conclusion: We successfully identified the ten hub shared genes linking the IS and MDD and constructed the regulatory networks for them that could serve as novel targeted therapy for the comorbidities.
Source: Frontiers in Genetics - March 31, 2023 Category: Genetics & Stem Cells Source Type: research

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