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Total 3248 results found since Jan 2013.

Life-Space Mobility: Normative Values from a National Cohort of U.S. Older Adults
CONCLUSIONS: We report US national norms for LSA among community-dwelling Black and White older adults. These norms can serve as a reference tool for determining if clinical and research samples have greater or lesser life-space mobility than typical older adults in the US for their age and sex.PMID:37480583 | DOI:10.1093/gerona/glad176
Source: Biol Sci Space - July 22, 2023 Category: Science Authors: Alexander X Lo Virginia G Wadley Cynthia J Brown D Leann Long Michael Crowe Virginia J Howard Richard E Kennedy Source Type: research

High rates of oral anticoagulation in atrial fibrillation patients observed in a large multi-specialty health system in the Northeast
ConclusionsWe show dramatically increased OAC usage among patients with AF and that NOACs comprise the large majority of OACs compared with previous studies. This suggests an association between widespread adoption of NOACs and increased oral anticoagulation rates. Future directions include assessing barriers to oral anticoagulation and developing interventions to reduce disparity in OAC use between clinics.
Source: Journal of Interventional Cardiac Electrophysiology - July 21, 2023 Category: Cardiology Source Type: research

Sleep Duration Is Associated With Subclinical Carotid Plaque Burden
CONCLUSIONS: The association between long sleep and subclinical carotid atherosclerosis may explain prior associations between long sleep and stroke.PMID:37470161 | DOI:10.1161/STROKEAHA.122.041967
Source: Atherosclerosis - July 20, 2023 Category: Cardiology Authors: Christian Agudelo Alberto R Ramos Hannah Gardener Ken Cheung Mitchell S V Elkind Ralph L Sacco Tatjana Rundek Source Type: research

Prevalence and predictors of low folate levels among stroke survivors in a country without mandatory folate food fortification: Analysis of a Ghanaian sample
Vitamin supplementation with folic acid (FA) reduces hyperhomocysteinemia (Hcy), a vascular risk factor with a strong, graded, and independent association with stroke and other vascular diseases.1 Available data suggest that a 25% reduction in total plasma homocysteine level is accompanied by a 19% lower stroke risk.1,2 Evidence from clinical trials on the effect of folate supplementation on mitigation of stroke risk has however been conflicting. A synthesis of clinical trial data has shown that supplemental FA had a neutral effect on reducing vascular events in countries with a mandate for folate fortification of food, fo...
Source: Journal of Stroke and Cerebrovascular Diseases - July 20, 2023 Category: Neurology Authors: Fred Stephen Sarfo, Richard Boateng, Priscilla Abrafi Opare-Addo, Rexford Adu Gyamfi, Samuel Blay Nguah, Bruce Ovbiagele Source Type: research

How to Keep Your Home Cool in Extreme Heat
Global temperatures have reached alarmingly high levels across the U.S., Europe, and Asia as heat waves set record highs this week. Parts of European countries including most of Italy, eastern Croatia, southern Spain, southern Bosnia and Herzegovina, and Montenegro are under red alert, the European Union’s Emergency Response Coordination Centre said on Wednesday. Meanwhile, as of July 18, Phoenix had experienced 19 consecutive days of 110°F temperatures or higher. And Beijing is also experiencing a record stretch of 95°F heat. The extreme heat comes as weather phenomenon El Niño, which occurs every tw...
Source: TIME: Health - July 19, 2023 Category: Consumer Health News Authors: Solcyre Burga Tags: Uncategorized climate change extreme weather healthscienceclimate Source Type: news

Trends in volume-regulated anion channel (VRAC) research: visualization and bibliometric analysis from 2014 to 2022
Conclusion: The aim of this bibliometric analysis is to provide an overall perspective for research on VRAC. VRAC has become a topic of increasing interest, and our analysis shows that it continues to be a prominent area. This study offers insights into the investigation of VRAC channel and may guide researchers in identifying new directions for future research.
Source: Frontiers in Pharmacology - July 19, 2023 Category: Drugs & Pharmacology Source Type: research

National reduction in cerebral arteriovenous malformation treatment correlated with increased rupture incidence
Conclusions After 2014, the likelihood of intervention for unruptured AVMs decreased while the incidence of ruptured AVMs increased. These findings suggest that fewer unruptured AVM treatments may lead to increases in AVM rupture incidence.
Source: Journal of NeuroInterventional Surgery - July 14, 2023 Category: Neurosurgery Authors: Luther, E., McCarthy, D. J., Burks, J., Govindarajan, V., Lu, V. M., Silva, M., Lang, M., Gross, B. A., Starke, R. M. Tags: Editor''s choice, Hemorrhagic stroke Source Type: research

Clinical experience with the Bendit steerable microcatheter: a new paradigm for endovascular treatment
Conclusions Our initial clinical experience with the Bendit21 microcatheter demonstrates its usefulness in achieving technical success in patients with challenging neurovascular conditions.
Source: Journal of NeuroInterventional Surgery - July 14, 2023 Category: Neurosurgery Authors: Killer-Oberpfalzer, M., Chapot, R., Orion, D., Barr, J. D., Cabiri, O., Berenstein, A. Tags: Open access, New devices New devices and techniques Source Type: research

Lifelong cerebrovascular disease burden among CADASIL patients: analysis from a global health research network
DiscussionEarly screening and targeted treatment strategies are warranted to help CADASIL patients with symptom management and risk mitigation.
Source: Frontiers in Neurology - July 14, 2023 Category: Neurology Source Type: research

Positive Phase III results for Roche ’s OCREVUS (ocrelizumab) twice a year, 10-minute subcutaneous injection in patients with multiple sclerosis
Phase III OCARINA II trial met primary and secondary endpointsOCREVUS twice a year, 10-minute injection has the potential to further improve the treatment experience and expand OCREVUS usage in MS centres with IV capacity limitations or without IV infrastructureOCREVUS remains the first and only therapy approved for both RMS and PPMS, and more than 300,000 people have been treated globallyBasel, 13 July 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the Phase III OCARINA II trial evaluating OCREVUS ® (ocrelizumab) as a twice a year 10-minute subcutaneous injection met its primary and secondary endpoints in...
Source: Roche Media News - July 13, 2023 Category: Pharmaceuticals Source Type: news

Correlation Between Intracranial Calcification and Extracranial Stenosis of the Internal Carotid Artery
We examined a population not selected for cerebral disease. This retrospective study contained 179 subjects aged 18 years and older from the Hawaii Diagnostic Radiology database. Extracranial internal carotid artery stenosis was determined using the absolute diameter, North American Symptomatic Carotid Endarterectomy Trial, and common carotid artery methods. Calcification was scored using the modified Woodcock method. A positive correlation between intracranial calcification and extracranial carotid stenosis was found using all three methods. Individuals with intracranial calcification were more likely to be older, have a ...
Source: Atherosclerosis - July 12, 2023 Category: Cardiology Authors: Julia R Jahansooz Andrew Ko Ryoko Hiroi Masako Matsunaga Enrique Carrazana Jason Viereck Source Type: research

Characteristics and Outcomes of Children with Cerebral Sinus Venous Thrombosis
ConclusionsCSVT, which has a U-shaped age distribution, is an uncommon condition in children. Stroke is common in children with CSVT, and it is associated with an increased need for mechanical ventilation and increased mortality. The need for mechanical ventilation is more common in infants, and it is associated with increased mortality across all age groups.
Source: Neurocritical Care - July 12, 2023 Category: Neurology Source Type: research