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Total 175 results found since Jan 2013.

The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK).
Conclusions: Higher plasma PAr was independently associated with increased risk of incident stroke in all participants and across all subgroups stratified by conventional risk predictors. Our novel findings point to and expand the range of inflammation and immune activation processes that may be relevant for the pathogenesis and prevention of stroke. This trial was registered at clinicaltrials.gov as NCT03013725. PMID: 29381795 [PubMed - in process]
Source: The American Journal of Clinical Nutrition - January 1, 2018 Category: Nutrition Authors: Zuo H, Tell GS, Ueland PM, Nygård O, Vollset SE, Midttun Ø, Meyer K, Ulvik A Tags: Am J Clin Nutr Source Type: research

The association of stroke severity with health-related quality of life in survivors of acute cerebrovascular disease and their informal caregivers during the first year post stroke: a survey study
ConclusionThe informal caregivers and survivors with TIA did not report lower than expected HRQoL. Increasing stroke severity was associated with decreasing HRQoL among survivors, but had limited predictive value among caregivers. Other factors may therefore be better indicators of ‘at risk’ caregivers.
Source: Quality of Life Research - May 8, 2020 Category: Health Management Source Type: research

Prevalence and covariates of uncontrolled hypertension in ischemic stroke survivors: the Norwegian stroke in the young study.
CONCLUSION: Uncontrolled hypertension was highly prevalent in ischemic stroke survivors <60 years and associated with co-presence of obesity and functional and structural arterial damage. Our results highlight the unmet potential and challenge of optimization of hypertension diagnosis and management in order to prevent recurrent vascular events in ischemic stroke survivors. PMID: 29334265 [PubMed - as supplied by publisher]
Source: Blood Pressure - January 16, 2018 Category: Hematology Tags: Blood Press Source Type: research

The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK)
ConclusionsHigher plasma PAr was independently associated with increased risk of incident stroke in all participants and across all subgroups stratified by conventional risk predictors. Our novel findings point to and expand the range of inflammation and immune activation processes that may be relevant for the pathogenesis and prevention of stroke. This trial was registered at clinicaltrials.gov as NCT03013725.
Source: American Journal of Clinical Nutrition - January 26, 2018 Category: Nutrition Source Type: research

Stroke severity quantification by critical care physicians in a mobile stroke unit
Conclusion Critical care physicians in a mobile stroke unit may use the NIHSS as a clinical tool in the assessment of patients experiencing acute stroke. The disagreement in NIHSS scores was mainly for very low values and would not have changed the handling of the patients.
Source: European Journal of Emergency Medicine - May 1, 2019 Category: Emergency Medicine Tags: Original articles Source Type: research

Asthma, asthma control and risk of stroke: the Nord-Trondelag Health Study (HUNT)
Conclusions: Active asthma was associated with modest increased risk of stroke in males and smokers independently of other conventional cardiovascular risk factors.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Cepelis, A., Brumpton, B., Laugsand, L., Langhammer, A., Janszky, I., Strand, L. Tags: Epidemiology Source Type: research

Tenecteplase versus alteplase for management of acute ischaemic stroke (NOR-TEST): a phase 3, randomised, open-label, blinded endpoint trial
This study is registered with ClinicalTrials.gov, number NCT01949948. Findings Between Sept 1, 2012, and Sept 30, 2016, 1107 patients met the inclusion criteria and seven patients were excluded because informed consent was withdrawn or eligibility for thrombolytic treatment was reconsidered. 1100 patients were randomly assigned to the tenecteplase (n=549) or alteplase (n=551) groups. The median age of participants was 77 years (IQR 64–79) and the median National Institutes of Health Stroke Scale score at baseline was 4 points (IQR 2–8). A final diagnosis other than ischaemic stroke or transient ischaemic attack was fou...
Source: The Lancet Neurology - August 3, 2017 Category: Neurology Source Type: research

Contrast ‐enhanced sonothrombolysis in acute ischemic stroke patients without intracranial large‐vessel occlusion
ConclusionCEST is safe in ischemic stroke patients without intracranial LVO. There were no differences in clinical outcomes between the treatment groups.
Source: Acta Neurologica Scandinavica - October 25, 2017 Category: Neurology Authors: C. E. Kvistad, A. Nacu, V. Novotny, N. Logallo, U. Waje ‐Andreassen, H. Naess, L. Thomassen Tags: ORIGINAL ARTICLE Source Type: research

Changes in survival and characteristics among older stroke unit patients —1994 versus 2012
ConclusionsThree ‐year survival in older Norwegian stroke patients treated on an SU remained stable despite improved treatment in the last decades. Differences in background characteristics may explain this lack of difference; patients in 2012 were older, more often living in supported care, and had higher prestro ke comorbidity; however, their strokes were milder and risk factors more often treated.
Source: Brain and Behavior - November 25, 2018 Category: Neurology Authors: Angela Susan Labberton, Ole Morten R ønning, Bente Thommessen, Mathias Barra Tags: ORIGINAL RESEARCH Source Type: research

A physical activity program is no more effective than standard care at maintaining upper limb activity in community-dwelling people with stroke: secondary outcomes from a randomized trial.
CONCLUSION: After intervention, there was no difference between the groups in terms of upper-limb activity. PMID: 31198048 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - June 13, 2019 Category: Rehabilitation Authors: Langhammer B, Ada L, Gunnes M, Ihle-Hansen H, Indredavik B, Askim T Tags: Clin Rehabil Source Type: research

Upright activity within the first week after stroke is associated with better functional outcome and health-related quality of life: A Norwegian multi-site study.
CONCLUSION: This study confirms the beneficial effect of upright activity applied during hospital stay in Norwegian stroke units. PMID: 26843147 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - February 9, 2016 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

Clinical Importance of Temporal Bone Features for the Efficacy of Contrast-Enhanced Sonothrombolysis: a Retrospective Analysis of the NOR-SASS Trial
AbstractContrast-enhanced sonothrombolysis (CEST) seems to be a safe and promising treatment in acute ischemic stroke. It remains unknown if temporal bone features may influence the efficacy of CEST. We investigated the association between different temporal bone features on admission computed tomography (CT) scan and the outcome in acute ischemic stroke patients included in the randomized Norwegian Sonothrombolysis in Acute Stroke Study (NOR-SASS). Patients diagnosed as stroke mimics and those with infratentorial stroke or with incorrect insonation were excluded. We retrospectively assessed temporal bone heterogeneity (pr...
Source: Translational Stroke Research - November 8, 2017 Category: Neurology Source Type: research

Effect of a dialogue-based intervention on psychosocial well-being 6 months after stroke in Norway: A randomized controlled trial.
CONCLUSION: Psychosocial well-being improved during the first 6 months after stroke in both arms of the trial, but no statistically significant benefit of the dialogue-based intervention was found compared with usual care. PMID: 31411337 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - August 15, 2019 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

Telemedicine remote controlled stroke evaluation and treatment, the experience of radiographers, paramedics and junior doctors in a novel rural stroke management team
CONCLUSIONS: The telemedicine-based, remote controlled, stroke evaluation and treatment was experienced, by the participants, to be well organised and of high quality. Communication and image reading appear to be the salient challenges. Regular training sessions and follow-up, as well as an evaluation of incidents by the project manager, proved to be of great importance in retaining and securing the continued running of the service and ensuring high-quality treatment. Further research is indicated in the comparison of this telemedicine service with stroke treatment given in a mainstream hospital.PMID:34090447 | DOI:10.1186/s12913-021-06591-1
Source: Rural Remote Health - June 6, 2021 Category: Rural Health Authors: Elin Kjelle Aud Mette Myklebust Source Type: research