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Total 22 results found since Jan 2013.

Incidence of First Stroke: A Population Study in Iceland Brief Reports
Conclusions— Incidence of first stroke in Iceland is similar to other Western countries. The high number of paroxysmal atrial fibrillation found during the 24-hour ECG suggests that atrial fibrillation may be underdiagnosed in patients with stroke.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Hilmarsson, A., Kjartansson, O., Olafsson, E. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Epidemiology Brief Reports Source Type: research

Ischemic stroke risk in a southeastern Chinese population: Insights from 5-lipoxygenase activating protein and phosphodiesterase 4D single-nucleotide polymorphisms.
CONCLUSION: No association was found between SNPs of ALOX5AP or PDE4D and the risk of overall ischemic stroke in a southeastern Chinese population. Interactions between these two genes were not risk factors for cerebral infarction. In atherothrombotic and small-artery disease subtypes, none of the seven SNPs was associated with any stroke risk; however, the ALOX5AP gene might be related to ischemic stroke incidence in females. PMID: 24485247 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - January 28, 2014 Category: Journals (General) Authors: Shao M, Yi X, Chi L, Lin J, Zhou Q, Huang R Tags: J Formos Med Assoc Source Type: research

Ischemic stroke risk in a southeastern Chinese population: Insights from 5-lipoxygenase activating protein and phosphodiesterase 4D single-nucleotide polymorphisms
Conclusion No association was found between SNPs of ALOX5AP or PDE4D and the risk of overall ischemic stroke in a southeastern Chinese population. Interactions between these two genes were not risk factors for cerebral infarction. In atherothrombotic and small-artery disease subtypes, none of the seven SNPs was associated with any stroke risk; however, the ALOX5AP gene might be related to ischemic stroke incidence in females.
Source: Journal of the Formosan Medical Association - May 20, 2015 Category: Journals (General) Source Type: research

Ozone is associated with cardiopulmonary and stroke emergency hospital visits in Reykjavik, Iceland 2003--2009
Conclusions: We found an increase in daily emergency hospital visits associated with O3, indicating that low-level exposure may trigger cardiopulmonary events or stroke.
Source: Environmental Health - April 8, 2013 Category: Environmental Health Authors: Hanne Krage CarlsenBertil ForsbergKadri MeisterThorarinn GíslasonAnna Oudin Source Type: research

Association between phosphodiesterase 4D polymorphism SNP83 and ischemic stroke
In conclusion, we found an association between SNP83 and IS in the overall population and in the Asian and Chinese populations, but not among Caucasians.
Source: Journal of the Neurological Sciences - December 23, 2013 Category: Neurology Authors: Yan Yan, Xiuping Luo, Jinlu Zhang, Li Su, Wenjie Liang, Guifeng Huang, Guangliang Wu, Guihua Huang, Lian Gu Tags: Reviews Source Type: research

What goes on when lightning strikes?
One lightning flash could run a whole power station – and there are 8 million strikes around the Earth every day. We still don't know what triggers the phenomenon, although a new theory proposes a role for cosmic raysA new theory from Russian researchers suggests that lightning may be a by-product of cosmic rays. Surprisingly, despite studying lightning for centuries, we are still not sure what triggers it.Divine attributionIn ancient times, the drama of thunder and lightning so clearly went beyond human scale that the phenomenon was handed wholesale to the gods. The Greeks had Zeus, the Romans Jupiter. At the head of th...
Source: Guardian Unlimited Science - May 25, 2013 Category: Science Authors: Brian Clegg Tags: Meteorology World news Natural disasters and extreme weather Features UK news The Observer Science Source Type: news

Editorial: Telomeres and Epigenetics in Endocrinology
This study was hypothesis-driven; the genetic variants were selected for being previously and substantially genotyped. The big sample size and the rich panel of other biomarkers allowed the authors to conduct much more detailed analyses on this topic. The third article by Provenzi et al. proposed their perspectives on the role of telomeres in premature birth and discussed the potential implications for early adversity and care in the neonatal intensive care unit (Pavanello et al.). Indeed, the speculation of telomeres in aging begins in the premature aging syndrome. It is thus interesting to examine if telomeres also play...
Source: Frontiers in Endocrinology - April 23, 2019 Category: Endocrinology Source Type: research

Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events
CONCLUSIONS AND RELEVANCE: A protein risk score was significantly associated with ASCVD events in primary and secondary event populations. When added to clinical risk factors, the protein risk score and polygenic risk score both provided statistically significant but modest improvement in discrimination.PMID:37606673 | DOI:10.1001/jama.2023.13258
Source: Atherosclerosis - August 22, 2023 Category: Cardiology Authors: Hannes Helgason Thjodbjorg Eiriksdottir Magnus O Ulfarsson Abhishek Choudhary Sigrun H Lund Erna V Ivarsdottir Grimur Hjorleifsson Eldjarn Gudmundur Einarsson Egil Ferkingstad Kristjan H S Moore Narimon Honarpour Thomas Liu Huei Wang Thomas Hucko Marc S S Source Type: research

No evidence Nordic diet prevents heart disease
Conclusion This was a well-designed randomised controlled trial that took place across several Nordic locations. The study took careful clinical measures of elements of metabolic syndrome at several points during the trial, and used food diaries at regular intervals to check compliance to the assigned diet. However, it provides no reliable proof that the ‘healthy’ Nordic diet is any better than the ‘average’ Nordic diet at improving components of metabolic syndrome and, in turn, no proof that it reduces the risk of cardiovascular disease. Importantly, this study found no significant results for its main aim (which...
Source: NHS News Feed - May 31, 2013 Category: Consumer Health News Tags: Food/diet Lifestyle/exercise Heart/lungs Source Type: news

From left bundle branch block to Icelandic whales: the multiple perils of atrial fibrillation management in the elderly.
We present the case of an elderly woman which demonstrates how AF therapy in aged individuals is particularly challenging for the presence of complex conditions. The rhythm- or the rate control strategy must be carefully chosen based on individual risk profile. Oral anticoagulant therapy must be wisely managed to maximize benefits-in terms of stroke and dementia control-and to reduce complications. PMID: 26319529 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - August 29, 2015 Category: Geriatrics Authors: Fumagalli S, Boni S, Gabbai D, Giannini I, Tarantini F, Marchionni N Tags: Aging Clin Exp Res Source Type: research

The Man Who Grew Eyes
The train line from mainland Kobe is a marvel of urban transportation. Opened in 1981, Japan’s first driverless, fully automated train pulls out of Sannomiya station, guided smoothly along elevated tracks that stand precariously over the bustling city streets below, across the bay to the Port Island. The island, and much of the city, was razed to the ground in the Great Hanshin Earthquake of 1995 – which killed more than 5,000 people and destroyed more than 100,000 of Kobe’s buildings – and built anew in subsequent years. As the train proceeds, the landscape fills with skyscrapers. The Rokkō mounta...
Source: Healthy Living - The Huffington Post - October 11, 2015 Category: Consumer Health News Source Type: news

Amgen Researchers Find Gene That Reduces Heart Attack Risk
Researchers at DeCode Genetics, an Icelandic unit of the biotechnology firm Amgen, have identified a new genetic variant that reduces the risk of heart disease and stroke by 34%.
Source: Forbes.com Healthcare News - May 18, 2016 Category: Pharmaceuticals Authors: Matthew Herper Source Type: news

Genetics of Cardiovascular Diseases. Lessons learned from a decade of genomics research in Iceland.
Authors: Arnar DO, Andersen K, Thorgeirsson G Abstract In the past ten years large scale genotyping has led to discoveries of sequence variants that confer risk of many common and complex diseases. Due to pioneering work done, in large part, at deCODE genetics in Reykjavik, discoveries from Iceland have contributed substantially to key advances in population genetics. In cardiovascular medicine a number of discoveries have been made, uncovering sequence variants that are associated with disorders such as coronary artery disease, atrial fibrillation, sick sinus syndrome, peripheral vascular disease, aortic aneurysm ...
Source: Scandinavian Cardiovascular Journal - August 31, 2016 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

A frameshift deletion in the sarcomere gene MYL4 causes early-onset familial atrial fibrillation
Conclusions</div>Through a population approach we found a loss of function mutation in the myosin gene <span style="font-style:italic;">MYL4</span> that, in the homozygous state, is completely penetrant for early-onset AF. The finding may provide novel mechanistic insight into the pathophysiology of this complex arrhythmia.</span>
Source: European Heart Journal - October 13, 2016 Category: Cardiology Source Type: research