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Condition: Osteoporosis

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Total 356 results found since Jan 2013.

Risk Factors for the Recurrence of Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis.
CONCLUSION: These findings strengthen clinical awareness of early warning to identify patients with potential relapse risk of BPPV and clinicians should counsel patients regarding the importance of follow-up after diagnosis of BPPV. PMID: 32776833 [PubMed - as supplied by publisher]
Source: Ear, Nose and Throat Journal - August 9, 2020 Category: ENT & OMF Authors: Li S, Wang Z, Liu Y, Cao J, Zheng H, Jing Y, Han L, Ma X, Xia R, Yu L Tags: Ear Nose Throat J Source Type: research

Romosozumab: A Novel Injectable Sclerostin Inhibitor With Anabolic and Antiresorptive Effects for Osteoporosis.
CONCLUSIONS: Romosozumab offers an alternative for patients with a high risk of osteoporotic fractures. Clinicians should avoid romosozumab in patients with a history of myocardial infarction or stroke in the past 12 months. PMID: 32862655 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - August 28, 2020 Category: Drugs & Pharmacology Authors: Nealy KL, Harris KB Tags: Ann Pharmacother Source Type: research

Epidemiological characteristics and related factors of frailty in older Chinese adults with hypertension: a population-based study
Conclusion: The current study provides the first evidence regarding the status of frailty in older Chinese adults with hypertension.
Source: Journal of Hypertension - October 9, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology and risk factors Source Type: research

When the Nervous System Turns Skeletal Muscles into Bones: How to Solve the Conundrum of Neurogenic Heterotopic Ossification
AbstractPurpose of ReviewNeurogenic heterotopic ossification (NHO) is the abnormal formation of extra-skeletal bones in periarticular muscles after damage to the central nervous system (CNS) such as spinal cord injury (SCI), traumatic brain injury (TBI), stroke, or cerebral anoxia. The purpose of this review is to summarize recent developments in the understanding of NHO pathophysiology and pathogenesis. Recent animal models of NHO and recent findings investigating the communication between CNS injury, tissue inflammation, and upcoming NHO therapeutics are discussed.Recent FindingsAnimal models of NHO following TBI or SCI ...
Source: Current Osteoporosis Reports - October 21, 2020 Category: Orthopaedics Source Type: research

Impact of diabetes in patients with COPD
Conclusion: According to our study, in the COPD population, diabetes seems to be associated with more comorbidities and a worse respiratory function while it does not increase exacerbations rate.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Slim, A., Kamoun, H., Saidane, A., Hdidene, Y., Ben Abdelghaffar, H., Smadhi, H., Greb, D., Akrout, I., Hassene, H., Fekih, L., Megdiche, M. L. Tags: Clinical problems Source Type: research

Characteristic of Clinical Studies on Baduanjin during 2000-2019: A Comprehensive Review.
Authors: Zhou J, Yu Y, Cao B, Li X, Wu M, Wen T, Xiong Y, Jia J, Zhao Y Abstract To date, a growing number of clinical studies have demonstrated the safety and health benefits from Baduanjin intervention. Based on this, our objective is to systematically retrieve and summarize the clinical studies on Baduanjin, with a view to providing more evidence-based evidence in support of the application of Baduanjin for healthcare, and to identify the shortcomings of existing research and provide feasibility suggest for further clinical research. Both four English language and four Chinese language electronic databases were ...
Source: Evidence-based Complementary and Alternative Medicine - November 6, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Regulatory role of microRNAs on PTEN signaling.
Abstract Phosphatase and tensin homolog (PTEN) gene encodes a tumor suppressor protein which is altered in several malignancies. This protein is a negative regulator of the PI3K/AKT signaling. Several transcription factors regulate the expression of PTEN in positive or negative directions. Moreover, numerous microRNAs (miRNAs) have functional interactions with PTEN and inhibit its expression. Suppression of PTEN can attenuate the response of cancer cells to chemotherapeutic agents. Based on the critical role of this tumor suppressor gene, the identification of negative regulators of its expression has practical si...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - November 7, 2020 Category: Drugs & Pharmacology Authors: Ghafouri-Fard S, Abak A, Shoorei H, Mohaqiq M, Majidpoor J, Sayad A, Taheri M Tags: Biomed Pharmacother Source Type: research

IJERPH, Vol. 17, Pages 9164: Towards a HR Framework for Developing a Health-Promoting Performance Culture at Work: A Norwegian Health Care Management Case Study
e The Norwegian Institute of Public Health (NIPH) states that Norway faces several major health challenges. Sick leave is at 6% and costs employers approximately EUR 1.75 billion annually. The NIPH proposes, with the support of the Public Health Act and the national strategy HealthCare21, that preventive measures should be developed to address negative lifestyle factors in order to decrease the number of new cases in the related disease groups (e.g., stroke, high blood pressure, type 2 diabetes, osteoporosis, obesity). The purpose of this article is to answer why and how organisations should develop a health-promoting ...
Source: International Journal of Environmental Research and Public Health - December 8, 2020 Category: Environmental Health Authors: Rune Bjerke Tags: Article Source Type: research

Gender Differences in Factors Associated with Clinically Meaningful Weight Loss among Adults Who Were Overweight or Obese: A Population-Based Cohort Study
Conclusion: Age, BMI status, physical activity, smoking status, family income, and health status were independent factors in males and females for weight management. However, further well-designed prospective studies are warranted to confirm our findings.Obes Facts
Source: Obesity Facts - December 22, 2020 Category: Eating Disorders & Weight Management Source Type: research

Association between body mass index and the risk of falls: a nationwide population-based study
ConclusionsObesity was associated with a greater risk of recurrent falls in women, whereas underweight seemed to be associated with a greater risk of falls in men.
Source: Osteoporosis International - January 7, 2021 Category: Orthopaedics Source Type: research

Dose-dependent effects of antipsychotics on efficacy and adverse effects in schizophrenia.
CONCLUSION: These findings could help clinicians to optimize antipsychotic treatment in patients with schizophrenia by balancing risks and benefits in clinical practice. However, further investigations with larger sample sizes and more robust study designs that focus on each antipsychotic agent are needed. PMID: 33417992 [PubMed - as supplied by publisher]
Source: Behavioural Brain Research - January 5, 2021 Category: Neurology Authors: Yoshida K, Takeuchi H Tags: Behav Brain Res Source Type: research

Zoledronic acid and fracture risk: a meta-analysis of 12 randomized controlled trials
CONCLUSIONS: Zoledronic acid is beneficial to reduce the incidence of fracture, while its benefits to reduce the mortality are only observed at the follow-up time of 24 months.PMID:33629326 | DOI:10.26355/eurrev_202102_24865
Source: European Review for Medical and Pharmacological Sciences - February 25, 2021 Category: Drugs & Pharmacology Authors: B He J-Q Zhao M-Z Zhang Z-X Quan Source Type: research