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Condition: Osteoporosis
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Total 249 results found since Jan 2013.

IJERPH, Vol. 17, Pages 9164: Towards a HR Framework for Developing a Health-Promoting Performance Culture at Work: A Norwegian Health Care Management Case Study
e The Norwegian Institute of Public Health (NIPH) states that Norway faces several major health challenges. Sick leave is at 6% and costs employers approximately EUR 1.75 billion annually. The NIPH proposes, with the support of the Public Health Act and the national strategy HealthCare21, that preventive measures should be developed to address negative lifestyle factors in order to decrease the number of new cases in the related disease groups (e.g., stroke, high blood pressure, type 2 diabetes, osteoporosis, obesity). The purpose of this article is to answer why and how organisations should develop a health-promoting ...
Source: International Journal of Environmental Research and Public Health - December 8, 2020 Category: Environmental Health Authors: Rune Bjerke Tags: Article Source Type: research

Relationship between bone strength index of the hemiparetic tibial diaphysis and muscle strength in people with chronic stroke: influence of muscle contraction type and speed
ConclusionsConcentric muscle power was more predictive of %SSD in p-SSI at the tibial diaphysis than other contraction types and may be an important target for intervention to promote bone health in people with chronic stroke.
Source: Osteoporosis International - November 7, 2020 Category: Orthopaedics Source Type: research

Characteristic of Clinical Studies on Baduanjin during 2000-2019: A Comprehensive Review.
Authors: Zhou J, Yu Y, Cao B, Li X, Wu M, Wen T, Xiong Y, Jia J, Zhao Y Abstract To date, a growing number of clinical studies have demonstrated the safety and health benefits from Baduanjin intervention. Based on this, our objective is to systematically retrieve and summarize the clinical studies on Baduanjin, with a view to providing more evidence-based evidence in support of the application of Baduanjin for healthcare, and to identify the shortcomings of existing research and provide feasibility suggest for further clinical research. Both four English language and four Chinese language electronic databases were ...
Source: Evidence-based Complementary and Alternative Medicine - November 6, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Risk of Incident Atrial Fibrillation With Zoledronic Acid Versus Denosumab: A Propensity Score –Matched Cohort Study
ABSTRACTZoledronic acid (ZA) is an effective agent in osteoporosis and malignancy ‐related bone disease but may be associated with increased risk of atrial fibrillation (AF), although current studies disagree on this risk. To examine the risk of incident AF among patients receiving ZA compared with denosumab in the first year of treatment, we performed a new‐user, active comp arator cohort study including privately insured Americans between January 1, 2010, and June 30, 2019. Individuals aged ≥50 years without known arrhythmia or advanced kidney disease who initiated ZA were 1:1 propensity score (PS)‐matched to i...
Source: Journal of Bone and Mineral Research - November 2, 2020 Category: Orthopaedics Authors: Kristin M D'Silva, Sara Jane Cromer, Elaine W Yu, Michael Fischer, Seoyoung C Kim Tags: Original Article Source Type: research

Impact of diabetes in patients with COPD
Conclusion: According to our study, in the COPD population, diabetes seems to be associated with more comorbidities and a worse respiratory function while it does not increase exacerbations rate.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Slim, A., Kamoun, H., Saidane, A., Hdidene, Y., Ben Abdelghaffar, H., Smadhi, H., Greb, D., Akrout, I., Hassene, H., Fekih, L., Megdiche, M. L. Tags: Clinical problems Source Type: research

Epidemiological characteristics and related factors of frailty in older Chinese adults with hypertension: a population-based study
Conclusion: The current study provides the first evidence regarding the status of frailty in older Chinese adults with hypertension.
Source: Journal of Hypertension - October 9, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology and risk factors Source Type: research

Romosozumab: A Novel Injectable Sclerostin Inhibitor With Anabolic and Antiresorptive Effects for Osteoporosis.
CONCLUSIONS: Romosozumab offers an alternative for patients with a high risk of osteoporotic fractures. Clinicians should avoid romosozumab in patients with a history of myocardial infarction or stroke in the past 12 months. PMID: 32862655 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - August 28, 2020 Category: Drugs & Pharmacology Authors: Nealy KL, Harris KB Tags: Ann Pharmacother Source Type: research

Risk Factors for the Recurrence of Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis.
CONCLUSION: These findings strengthen clinical awareness of early warning to identify patients with potential relapse risk of BPPV and clinicians should counsel patients regarding the importance of follow-up after diagnosis of BPPV. PMID: 32776833 [PubMed - as supplied by publisher]
Source: Ear, Nose and Throat Journal - August 9, 2020 Category: ENT & OMF Authors: Li S, Wang Z, Liu Y, Cao J, Zheng H, Jing Y, Han L, Ma X, Xia R, Yu L Tags: Ear Nose Throat J Source Type: research

Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
CONCLUSION: Eight biased TCM constitutions were closely related to specific diseases, and could be used to guide individualized prevention and treatment. More rigorously designed studies are recommended to further verify the constitution-disease relationship. PMID: 32744037 [PubMed - in process]
Source: Journal of Traditional Chinese Medicine - July 31, 2020 Category: Complementary Medicine Authors: Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L Tags: J Tradit Chin Med Source Type: research

Factors associated with fracture after stroke and TIA: a long-term follow-up
ConclusionStroke was positively associated with fracture in patients<  80 years, while TIA was positively associated with fracture in patients ≥ 80 years and females. Dementia and analgesic therapy were also associated with fracture after either stroke or TIA.
Source: Osteoporosis International - July 9, 2020 Category: Orthopaedics Source Type: research

Blindness increases the risk for hip fracture and vertebral fracture but not the risk for distal radius fracture: a longitudinal follow-up study using a national sample cohort
ConclusionThe risks for hip fracture and vertebral fracture were significantly higher in the blindness group. However, the risk for distal radius fracture was not related to visual impairment including blindness.
Source: Osteoporosis International - July 5, 2020 Category: Orthopaedics Source Type: research

Nonclinical cardiovascular safety evaluation of romosozumab, an inhibitor of sclerostin for the treatment of osteoporosis in postmenopausal women at high risk of fracture.
Abstract Romosozumab (EVENITY™ [romosozumab-aqqg in the US]) is a humanized monoclonal antibody that inhibits sclerostin and has been approved in several countries for the treatment of osteoporosis in postmenopausal women at high risk of fracture. Sclerostin is expressed in bone and aortic vascular smooth muscle (AVSM). Its function in AVSM is unclear but it has been proposed to inhibit vascular calcification, atheroprogression, and inflammation. An increased incidence of positively adjudicated serious cardiovascular adverse events driven by an increase in myocardial infarction and stroke was observed in romosoz...
Source: Regulatory Toxicology and Pharmacology : RTP - June 22, 2020 Category: Toxicology Authors: Turk JR, Deaton AM, Yin J, Stolina M, Felx M, Boyd G, Bienvenu JG, Varela A, Guillot M, Holdsworth G, Wolfreys A, Dwyer D, Kumar SV, de Koning EM, Qu Y, Engwall M, Locher K, Ward LD, Glaus C, He YD, Boyce RW Tags: Regul Toxicol Pharmacol Source Type: research

Risk Factors for the Occurrence of Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis
Conclusion: Female gender, vitamin D deficiency, osteoporosis, migraine, head trauma, and high TC level were risk factors for the occurrence of BPPV. However, the effects of other risk factors on BPPV occurrence need further investigations.
Source: Frontiers in Neurology - June 22, 2020 Category: Neurology Source Type: research

An Appraisal of the Role of Previously Reported Risk Factors in the Age at Menopause Using Mendelian Randomization
ConclusionOur results help to identify the risk factors of ANM via a genetics approach and future research into the biological mechanism could further help with targeted prevention for early menopause.
Source: Frontiers in Genetics - May 28, 2020 Category: Genetics & Stem Cells Source Type: research