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Condition: Osteoporosis
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Total 249 results found since Jan 2013.

Cigarette smoking has a positive and independent effect on testosterone levels.
Authors: Wang W, Yang X, Liang J, Liao M, Zhang H, Qin X, Mo L, Lv W, Mo Z Abstract Previous studies have suggested that testosterone levels are linked to a variety of diseases, such as cardiovascular disease, type-2 diabetes, the metabolic syndrome, erectile dysfunction, depression, stroke and osteoporosis. Since cigarette smoking is a major health problem and highly prevalent among men, several groups have studied the effects of cigarette smoking on testosterone levels in men. However, the results have been conflicting. Our objectives were to examine the association of cigarette smoking and serum levels of sex ho...
Source: Hormones - December 2, 2014 Category: Endocrinology Tags: Hormones (Athens) Source Type: research

Depression: It's Not Just in Your Head, It's Also in Your Genes
This study demonstrated shorter telomeres in daughters of moms who had depression and greater hormonal reactivity to stress in these girls. When the girls were followed until age 18, 60 percent of those in the high-risk group developed depression, a condition that was not evident when they were first studied. The telomere was a biomarker, an individual hallmark that a person is at higher risk for an illness -- in this case for depression. We already knew that shortened telomeres were a risk factor for chronic, physical diseases but now the evidence is emerging for its likely role in depression. Should you go out and get ...
Source: Healthy Living - The Huffington Post - November 28, 2014 Category: Consumer Health News Source Type: news

Prolonged risk of subtrochanteric and diaphyseal femur fractures after discontinuing alendronate treatment: A nationwide nested case-control study in Taiwan
Conclusion Discontinuation of alendronate therapy did not reduce the risk of subtrochanteric femoral fractures until it was discontinued for >5 years. In conclusion, alendronate use significantly increased the risk of subtrochanteric femoral fractures, and the risk may persist for 5 years after discontinuation.
Source: Journal of Clinical Gerontology and Geriatrics - November 27, 2014 Category: Geriatrics Source Type: research

Health care costs for prostate cancer patients receiving androgen deprivation therapy: treatment and adverse events.
CONCLUSIONS: The economic burden of adverse events is relevant to programs and policies from clinic to government, and that burden merits consideration in the risks and benefits of adt. PMID: 24940106 [PubMed]
Source: Current Oncology - November 19, 2014 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

New strategies for osteoporosis patients previously managed with strontium ranelate
The aim of this article is to describe potential alternatives to patients no longer eligible for management with strontium ranelate for osteoporosis according to the recommendations by the European Medicines Agency. A systematic search of Pubmed was done for papers on fracture efficacy of various treatments for osteoporosis, and potential harms especially in terms of cardiovascular events and stroke. The results showed that drugs more efficacious in terms of relative risk reduction of fractures than strontium ranelate were alendronate, risedronate, zoledronate, and denosumab. Raloxifene, as for strontium, may be associated...
Source: Therapeutic Advances in Musculoskeletal Disease - November 19, 2014 Category: Orthopaedics Authors: Vestergaard, P. Tags: Reviews Source Type: research

A population-based five-year study on the risk of stroke in patients with osteoporosis in Taiwan
This study was intended to estimate the risk of stroke among elder persons aged ≥50years within five years of being diagnosed with osteoporosis.
Source: Bone - November 15, 2014 Category: Orthopaedics Authors: Chia-Hsien Lin, Wei-Chiao Chang, Chun-Nan Kuo, Hann-Chin Yu, Chien-Chang Yang, Yea-Wen Lin, Kuo-Sheng Hung, Wei-Pin Chang Tags: Original Full Length Article Source Type: research

Newly diagnosed gastroesophageal reflux disease increased the risk of acute exacerbation of chronic obstructive pulmonary disease during the first year following diagnosis – a nationwide population‐based cohort study
ConclusionThis study demonstrated that GERD is an independent risk factor for AECOPD. Caution should be exercised when assessing GERD symptoms in patients with COPD.
Source: International Journal of Clinical Practice - October 31, 2014 Category: Internal Medicine Authors: Y. H. Lin, C. L. Tsai, L. N. Chien, H. Y. Chiou, C. Jeng Tags: Original Paper Source Type: research

The Causal Effect of Vitamin D Binding Protein (DBP) Levels on Calcemic and Cardiometabolic Diseases: A Mendelian Randomization Study
Conclusions DBP has no demonstrable causal effect on any of the diseases or traits investigated here, except 25OHD levels. It remains to be determined whether 25OHD has a causal effect on these outcomes independent of DBP.Please see later in the article for the Editors' Summary
Source: PLoS Medicine - October 28, 2014 Category: Internal Medicine Authors: Aaron Leong et al. Source Type: research

Predictors of low bone mineral density of the stroke-affected hip among ambulatory individuals with chronic stroke
Conclusion Low BMD of the stroke-affected side hip is prevalent in over a third of individuals with lower limb motor impairments. These individuals may be at particular risk of accelerated loss of BMD at the hip from asymmetrical gait pattern and poor affected-side ankle dorsiflexor strength. These impairments are intervention targets that may be addressed during rehabilitation which includes resistance training and addresses gait impairments.
Source: Osteoporosis International - October 22, 2014 Category: Orthopaedics Source Type: research

Increased risk of stroke among hip fracture patients: a nationwide cohort study
Conclusions Hip fracture is independently associated with a subsequent risk of stroke.
Source: Osteoporosis International - October 10, 2014 Category: Orthopaedics Source Type: research

Hip fracture after first‐ever stroke: a population‐based study
ConclusionsThese findings imply that osteoporosis may play a major role in the occurrence of hip fracture in the first four years after a first‐ever stroke. Early intervention to prevent bone loss should be regarded as an important part in stroke management, especially in older females, and should be sustained for four years at least. The benefit of antidepressants in stroke patients should be weighed against the increased risk of hip fracture.
Source: Acta Neurologica Scandinavica - September 28, 2014 Category: Neurology Authors: H.‐L. Lin, H.‐C. Lin, Y.‐F. Tseng, H.‐H. Liao, J. A. Worly, C.‐Y. Pan, C.‐Y. Hsu Tags: Original Article Source Type: research

Osteoporosis as an independent risk factor for silent brain infarction and white matter changes in men and women: the PRESENT project
Conclusions Severe bone mass loss may be an independent risk factor for brain WMC/SI in men and women. Low BMD may cause brain WMC/SI in the step that leads to stroke. Although there are well-designed studies on the prevention of cerebral infarction in patients with brain WMC/SI, a specific prevention method, such as aspirin, should be used for patients with low BMD who have WMC/SI. Screening for low BMD as an independent vascular risk factor in healthy subjects may be required to prevent stroke.
Source: Osteoporosis International - September 26, 2014 Category: Orthopaedics Source Type: research

Is the negative relationship between obesity and bone mineral content greater for older women?
In conclusion, this study shows that the negative relationship between waist circumference and BMC in the femoral neck and total hip is greater for older women.
Source: Journal of Bone and Mineral Metabolism - September 1, 2014 Category: Orthopaedics Source Type: research

Assessment of Risk in Chronic Airways Disease Evaluation (ARCADE): Protocol and preliminary data.
Abstract Chronic obstructive pulmonary disease (COPD) is a multisystem disease. Established comorbidities include cardiovascular disease, osteoporosis, loss of muscle mass and function, depression, and impaired quality of life. The natural history is not well understood. The Assessment of Risk in Chronic Airways Disease Evaluation (ARCADE) is a longitudinal study of comorbidities in COPD. The primary aims are to delineate the progression and interrelationships of cardiovascular disease and associated comorbidities. Each year ARCADE aims to recruit 250 patients diagnosed with COPD and 50 comparators (free from resp...
Source: Chronic Respiratory Disease - August 26, 2014 Category: Respiratory Medicine Authors: Gale NS, Albarrati AM, Munnery MM, Munnery IC, Irfan M, Bolton CE, Rambaran CN, Singer RM, Cockcroft JR, Shale DJ Tags: Chron Respir Dis Source Type: research

An adapted adult day centre for older adults with sensory impairment
The MAB-Mackay Rehabilitation Centre runs a Day Centre Programme whose objectives are to maintain or improve the seniors’ biological, psychological, and social health while delaying or avoiding institutionalization. Activities include walking groups, language courses, and memory games, supervised by an interdisciplinary team. Services include rehabilitation follow-up and referrals to community resources. The present study reports on the impact of the Day Centre on the holistic health of older adults with visual impairment. Between September 2011 and October 2012, 30 newly referred clients (age = 71–98 years, M ...
Source: British Journal of Visual Impairment - August 20, 2014 Category: Opthalmology Authors: Wittich, W., Murphy, C., Mulrooney, D. Tags: Research Articles Source Type: research