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Condition: Osteoporosis
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Total 249 results found since Jan 2013.

Salt content in cheese 'too high', say campaigners
Conclusion This study highlights the wide variation in salt content that can be found in cheese. Labelling is now making it easier to make an informed choice regarding where you wish your maximum recommended level of 6g of salt per day to come from. This is particularly important when assessing which cheese is the best option for children, who should consume lower levels of salt. The study showed that there were many types of cheese that have a reasonably low salt content, including cottage cheese, cream cheese, mozzarella and Emmental. However, cheese is generally calorific, and overconsumption can lead to overweight an...
Source: NHS News Feed - August 7, 2014 Category: Consumer Health News Tags: Heart/lungs Food/diet Source Type: news

Calcium supplements associated with increased risk of cardiovascular death in men but not women
Commentary on: Xiao Q, Murphy RA, Houston DK, et al.. Dietary and supplemental calcium intake and cardiovascular disease mortality: the National Institutes of Health-AARP diet and health study. JAMA Intern Med 2013;173:639–46 Implications for practice and research Calcium supplements increase cardiovascular risk. The role of calcium supplements in the management of osteoporosis should be reconsidered. Context In 2008, a randomised controlled trial (RCT) suggested that calcium supplements might increase the risk of cardiovascular events.1 Subsequent meta-analyses of RCTs examining calcium monotherapy and calcium and v...
Source: Evidence-Based Nursing - June 17, 2014 Category: Nursing Authors: Bolland, M. J., Grey, A. Tags: Primary health care, Drugs: cardiovascular system, Stroke, Diet, Ischaemic heart disease, Osteoporosis Source Type: research

Controversy Regarding the Association of High Calcium Intake and Increased Risk for Cardiovascular Disease
Calcium intake has been shown to be associated with beneficial effects regarding hypertension, coronary heart disease (CHD), vascular disease, and stroke by several prospective cohort studies. However, recent studies have questioned the beneficial cardiovascular effects of calcium intake and instead have shown that high calcium intake is associated with an increased risk for CHD and stroke. These findings have created controversy and concern among physicians, because calcium is consumed by a large number of older men and women to prevent osteoporosis and bone fractures. Based on the methods of patient self‐reporting of c...
Source: The Journal of Clinical Hypertension - May 1, 2014 Category: Cardiology Authors: Steven G. Chrysant, George S. Chrysant Tags: Commentary Source Type: research

Cohort Profile: The Namwon Study and the Dong-gu Study
These two cohorts were designed to examine the increasing burden of chronic diseases among Korean populations. The studies investigated determinants for stroke, osteoporosis, dementia and cancer among middle-aged and elderly Korean populations. The Namwon Study baseline survey was performed between 2004 and 2007 (n = 10 667), and followed up 4 years later (n = 8157, follow-up rate = 76.5%). The baseline survey of the Dong-gu Study was administered over 2007–2010 (n = 9260), and will be followed up between 2014 and 2015. Questionnaires included assessment of cognitive function, psychiatric health and lifestyle factors...
Source: International Journal of Epidemiology - April 23, 2014 Category: Epidemiology Authors: Kweon, S.-S., Shin, M.-H., Jeong, S.-K., Nam, H.-S., Lee, Y.-H., Park, K.-S., Ryu, S.-Y., Choi, S.-W., Kim, B.-H., Rhee, J.-A., Zheng, W., Choi, J.-S. Tags: Cohort Profiles Source Type: research

Obstructive Sleep Apnea and Risk of Osteoporosis: A Population-Based Cohort Study in Taiwan.
Conclusion: People diagnosed with OSA are at increased risk for subsequent osteoporosis. PMID: 24735427 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - April 15, 2014 Category: Endocrinology Authors: Chen YL, Weng SF, Shen YC, Chou CW, Yang CY, Wang JJ, Tien KJ Tags: J Clin Endocrinol Metab Source Type: research

Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men.
CONCLUSIONS: Vitamin D alone is unlikely to prevent fractures in the doses and formulations tested so far in older people. Supplements of vitamin D and calcium may prevent hip or any type of fracture. There was a small but significant increase in gastrointestinal symptoms and renal disease associated with vitamin D and calcium. This review found that there was no increased risk of death from taking calcium and vitamin D. PMID: 24729336 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - April 14, 2014 Category: Journals (General) Authors: Avenell A, Mak JC, O'Connell D Tags: Cochrane Database Syst Rev Source Type: research

Relationship Between Bone Mass And Muscle Weakness In Chronic Neurological Diseases (P3.036)
Conclusions: This study demonstrates greater commitment tendency to bone density in regions with weakness, compared to those without it, this could be related to disuse. This series had insufficient vitamin D. The neurologist should consider bone mass evaluation in patients with chronic muscle weakness.Disclosure: Dr. Gutierrez has nothing to disclose. Dr. Rodriguez has nothing to disclose. Dr. Garcea has nothing to disclose. Dr. Rey has nothing to disclose. Dr. Lepera has nothing to disclose. Dr. Monica has nothing to disclose. Dr. Monica has nothing to disclose. Dr. Eduardo has nothing to disclose. Dr. Berenice has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Gutierrez, M., Rodriguez, G. E., Garcea, D., Rey, R., Lepera, S., Monica, E., Monica, D., Eduardo, K., Berenice, S. Tags: General Neurology II Source Type: research

Clinical prediction rules in practice: review of clinical guidelines and survey of GPs.
CONCLUSION: GPs use CPRs to guide management but also to comply with local policy requirements. Future research could focus on which clinical areas clinicians would most benefit from CPRs and promoting the use of robust, externally validated CPRs. PMID: 24686888 [PubMed - in process]
Source: The British Journal of General Practice - April 1, 2014 Category: Primary Care Authors: Plüddemann A, Wallace E, Bankhead C, Keogh C, Van der Windt D, Lasserson D, Galvin R, Moschetti I, Kearley K, O'Brien K, Sanders S, Mallett S, Malanda U, Thompson M, Fahey T, Stevens R Tags: Br J Gen Pract Source Type: research

Agreement between self-reported and general practitioner-reported chronic conditions among multimorbid patients in primary care - results of the MultiCare cohort study
Conclusions: For multimorbidity research, the knowledge of diseases with high disagreement levels between the patients' perceived illnesses and their physicians' reports is important. The analysis shows that different patient characteristics have an impact on the agreement. Findings from this study should be included in the development of clinical guidelines for multimorbidity aiming to optimize health care. Further research is needed to identify more reasons for disagreement and their consequences in health care.Trial registration: ISRCTN89818205.
Source: BMC Family Practice - March 1, 2014 Category: Primary Care Authors: Heike HansenIngmar SchäferGerhard SchönSteffi Riedel-HellerJochen GensichenSiegfried WeyererJuliana PetersenHans-Helmut KönigHorst BickelAngela FuchsSusanne HöfelsBirgitt WieseKarl WegscheiderHendrik van den BusscheMartin Scherer Source Type: research

Identifying factors associated with changes in physical functioning in an older population
ConclusionsOlder persons with stroke, Parkinson's disease, diabetes, osteoporosis, geriatric conditions and poor short physical performance battery score should be considered as the target of prevention against functional decline. Those not living with spouses, with poor self‐rated health, with low social support, being underweight or obese and with a sedentary lifestyle might also require major attention. Geriatr Gerontol Int 2014; ●●: ●●–●●.
Source: Geriatrics and Gerontology International - February 1, 2014 Category: Geriatrics Authors: Chun‐Min Chen, Wen‐Chiung Chang, Tzuo‐Yun Lan Tags: Review Article Source Type: research

Bone Mineral Density and Incidence of Stroke: European Prospective Investigation Into Cancer-Norfolk Population-Based Study, Systematic Review, and Meta-Analysis Clinical Sciences
Conclusions— Bone mineral density predicts total stroke risk. The evidence is stronger in women with regard to the continuous relationship.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Myint, P. K., Clark, A. B., Kwok, C. S., Loke, Y. K., Yeong, J. K.-Y., Luben, R. N., Wareham, N. J., Khaw, K.-T. Tags: Epidemiology Clinical Sciences Source Type: research

The association between self-reported history of physical diseases and psychological distress in a community-dwelling Japanese population: the Ohsaki Cohort 2006 Study
Conclusions: Subjects with a history of physical disease were significantly and positively associated with psychological distress, and social support did not modify this association for most physical diseases. Even after patients have left hospital following treatment for physical disease, they require continuous monitoring for psychological distress by doctors and paramedics.
Source: The European Journal of Public Health - January 24, 2014 Category: Journals (General) Authors: Nakaya, N., Kogure, M., Saito-Nakaya, K., Tomata, Y., Sone, T., Kakizaki, M., Tsuji, I. Tags: Mental health Source Type: research

Falls and comorbidity: The pathway to fractures.
CONCLUSIONS: The results suggest that the overall reduction in fractures can be explained by reduction in falls related comorbidity. PMID: 24434943 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Public Health - January 16, 2014 Category: Global & Universal Authors: Jørgensen TS, Hansen AH, Sahlberg M, Gislason GH, Torp-Pedersen C, Andersson C, Holm E Tags: Scand J Public Health Source Type: research

Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.
Abstract A family of detoxifying enzymes called aldehyde dehydrogenases (ALDHs) has been a subject of recent interest, as its role in detoxifying aldehydes that accumulate through metabolism and to which we are exposed from the environment has been elucidated. Although the human genome has 19 ALDH genes, one ALDH emerges as a particularly important enzyme in a variety of human pathologies. This ALDH, ALDH2, is located in the mitochondrial matrix with much known about its role in ethanol metabolism. Less known is a new body of research to be discussed in this review, suggesting that ALDH2 dysfunction may contribute...
Source: Physiological Reviews - January 1, 2014 Category: Physiology Authors: Chen CH, Ferreira JC, Gross ER, Mochly-Rosen D Tags: Physiol Rev Source Type: research

Targeting Aldehyde Dehydrogenase 2: New Therapeutic Opportunities
A family of detoxifying enzymes called aldehyde dehydrogenases (ALDHs) has been a subject of recent interest, as its role in detoxifying aldehydes that accumulate through metabolism and to which we are exposed from the environment has been elucidated. Although the human genome has 19 ALDH genes, one ALDH emerges as a particularly important enzyme in a variety of human pathologies. This ALDH, ALDH2, is located in the mitochondrial matrix with much known about its role in ethanol metabolism. Less known is a new body of research to be discussed in this review, suggesting that ALDH2 dysfunction may contribute to a variety of h...
Source: Physiological Reviews - January 1, 2014 Category: Physiology Authors: Chen, C.-H., Ferreira, J. C. B., Gross, E. R., Mochly-Rosen, D. Tags: Articles Source Type: research