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Condition: Osteoporosis
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Total 249 results found since Jan 2013.

Bone Mineral Density and Incidence of Stroke: European Prospective Investigation Into Cancer-Norfolk Population-Based Study, Systematic Review, and Meta-Analysis Clinical Sciences
Conclusions— Bone mineral density predicts total stroke risk. The evidence is stronger in women with regard to the continuous relationship.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Myint, P. K., Clark, A. B., Kwok, C. S., Loke, Y. K., Yeong, J. K.-Y., Luben, R. N., Wareham, N. J., Khaw, K.-T. Tags: Epidemiology Clinical Sciences Source Type: research

The relationship between bone mineral density and cerebral pulsatility index in patients with acute ischemic stroke (P6.025)
Conclusions: Our findings indicate that decreased BMD may be associated with atherosclerosis in the cerebral circulation.Disclosure: Dr. Park has nothing to disclose. Dr. Park has nothing to disclose. Dr. Suk has nothing to disclose. Dr. Koh has nothing to disclose. Dr. Hwang has nothing to disclose. Dr. Song has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Park, J. H., Park, J. H., Suk, S.-H., Koh, I.-S., Hwang, S.-H., Song, H.-K., Lee, J. H. Tags: Ischemic Stroke Diagnosis Source Type: research

Factors associated with fracture after stroke and TIA: a long-term follow-up
ConclusionStroke was positively associated with fracture in patients<  80 years, while TIA was positively associated with fracture in patients ≥ 80 years and females. Dementia and analgesic therapy were also associated with fracture after either stroke or TIA.
Source: Osteoporosis International - July 9, 2020 Category: Orthopaedics Source Type: research

Calcium supplements linked to post-stroke dementia in women
Conclusion The media paint this as a troubling study for older women who take calcium to strengthen their bones. However the small size of the study (only 98 women took calcium supplements, and only 14 of those got dementia) and its observational nature mean that we cannot rely on the results. As the researchers mention, it is possible that those taking supplements were less healthy than those that didn't in some unmeasured way. Further research may improve our confidence in these results. Broken bones are not a trivial matter for older people – a broken hip can be the difference between being able to live independentl...
Source: NHS News Feed - August 18, 2016 Category: Consumer Health News Tags: Neurology Medication Older people Source Type: news

Risk of hip fracture following stroke, a meta-analysis of 13 cohort studies
This study systematically reviews prospective and retrospective cohort studies evaluating the risk of hip fracture following stroke. Stroke survivors are at high risk of hip fracture and had a 1.5-fold increased risk compared to stroke-free men and women of the same age. Hip fracture often occurs in ageing and female stroke patients. We performed a meta-analysis to summarize evidence from prospective and retrospective cohort studies about the risk of hip fracture following stroke. We identified English and non-English publications in MEDLINE and EMBASE using stroke and fracture as keywords to 31 December 2015. The data of ...
Source: Osteoporosis International - August 12, 2016 Category: Orthopaedics Source Type: research

Increased risk of stroke among hip fracture patients: a nationwide cohort study
Conclusions Hip fracture is independently associated with a subsequent risk of stroke.
Source: Osteoporosis International - October 10, 2014 Category: Orthopaedics Source Type: research

The impact of preadmission oral bisphosphonate use on 30-day mortality following stroke: a population-based cohort study of 100,043 patients
Conclusion: We found no overall evidence that preadmission bisphosphonate use increases 30-day mortality following stroke. Keywords: prognosis, oral bisphosphonates, stroke, mortality, cardiovascular disease, osteoporosis treatment
Source: Clinical Epidemiology - August 23, 2015 Category: Epidemiology Tags: Clinical Epidemiology Source Type: research

Associations between stroke type, stroke severity, and pre-stroke osteoporosis with the risk of post-stroke fracture: A nationwide population-based study
BackgroundRecognizing the post-stroke fracture risk factors is crucial for targeted intervention and primary fracture prevention. We aimed to investigate whether stroke types, stroke severity, and pre-stroke osteoporosis are associated with post-stroke fracture.MethodsIn a nationwide cohort, we identified previously fracture-free patients who suffered from first-ever stroke, either acute ischemic stroke (AIS) or intracerebral hemorrhage (ICH), between 2003 and 2015. Information regarding stroke severity, osteoporosis, comorbidity, and medication information was collected.
Source: Journal of the Neurological Sciences - May 27, 2021 Category: Neurology Authors: Hung-Ping Wang, Sheng-Feng Sung, Hsin-Yi Yang, Wan-Ting Huang, Cheng-Yang Hsieh Source Type: research

Risk of osteoporotic fractures following stroke in older persons
Conclusion To evaluate the relative risk of stroke survivors for osteoporotic fractures, functional status appears to be a relevant parameter.
Source: Osteoporosis International - January 8, 2015 Category: Orthopaedics Source Type: research

Chronic effects of stroke on hip bone density and tibial morphology: a longitudinal study
Conclusions There is evidence of continuous trabecular bone loss in the paretic tibial distal epiphysis among chronic stroke patients, but it tends to plateau after 2 years of stroke onset. The steady state may have been reached earlier in the hip and tibial diaphysis.
Source: Osteoporosis International - September 2, 2015 Category: Orthopaedics Source Type: research

Drug treatment strategies for osteoporosis in stroke patients.
Authors: Hsieh CY, Sung SF, Huang HK Abstract Introduction: Osteoporosis and subsequent fractures are well-recognized complications of stroke. However, drug treatment strategies for osteoporosis after stroke have been rarely discussed in the current guidelines for the management of stroke or osteoporosis.Areas covered: The authors review the epidemiology, characteristics, pathophysiology, and risk prediction of post-stroke osteoporosis and fractures. Then they provide an overview of existing evidence regarding drug treatment strategies for osteoporosis in stroke patients. They also review the effects on bone minera...
Source: Expert Opinion on Pharmacotherapy - March 11, 2020 Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research

Gait speed and spasticity are independently associated with estimated failure load in the distal tibia after stroke: an HR-pQCT study
ConclusionThe paretic distal tibia showed more compromised vBMD, cortical area, cortical thickness, and estimated failure load than the non-paretic tibia. Gait speed and spasticity were independently associated with estimated failure load. As treatment programs focusing on these potentially modifiable stroke-related impairments are feasible to administer, future studies are needed to determine the efficacy of such intervention strategies for improving bone strength in individuals with chronic stroke.
Source: Osteoporosis International - October 12, 2021 Category: Orthopaedics Source Type: research

Thoracic Aortic < sup > 18 < /sup > F-Sodium Fluoride Activity and Ischemic Stroke in Patients With Established Cardiovascular Disease
CONCLUSIONS: In patients with established cardiovascular disease, thoracic aortic 18F-sodium fluoride activity is associated with the progression of atherosclerosis and future ischemic stroke. Arterial 18F-sodium fluoride activity identifies localized areas of atherosclerotic disease activity that are directly linked to disease progression and downstream regional clinical atherothrombotic events. (DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury [DIAMOND], NCT02110303; Study Investigating the Effect of Drugs Used to Treat Osteoporosis on the Progression of Calcific Aortic Stenosis [SALTIRE II], NCT02132026; ...
Source: Atherosclerosis - February 20, 2022 Category: Cardiology Authors: Alexander J Fletcher Yong Y Tew Evangelos Tzolos Shruti S Joshi Jakub Kaczynski Jennifer Nash Samuel Debono Maria Lembo Jacek Kwiecinski Rong Bing Maaz B J Syed Mhairi K Doris Edwin J R van Beek Alistair J Moss William S Jenkins Niki L Walker Nikhil V Jos Source Type: research

Saving bones without risking brain —bisphosphonates and risk of stroke: matched case-control study
ConclusionsWe found no association between bisphosphonate treatment and risk of stroke, after adjusting for other confounders.
Source: Osteoporosis International - June 16, 2019 Category: Orthopaedics Source Type: research