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Condition: Inflammatory Bowel Disease

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Total 222 results found since Jan 2013.

Crohn ' s, Colitis Increase Risk for Acute Arterial Events Crohn ' s, Colitis Increase Risk for Acute Arterial Events
Ischemic events and stroke are significantly more frequent in patients with inflammatory bowel disease than in the general population, according to a large French study.Medscape Medical News
Source: Medscape Medical News Headlines - February 17, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

An unusual presentation of Listeria monocytogenes rhombencephalitis
We describe a case of 52-year-old woman with a medical history of Crohn's disease presented abrupt fever, asymmetrical multiple cranial nerve palsies and focal neurological symptoms localized to the brainstem. The patient was initially diagnosed with ischaemic stroke, because of acute clinical course and results of neuroimaging. Cerebrospinal fluid analysis revealed mild infection with negative Gram staining and culture. Final diagnosis of Listeria monocytogenes brainstem infection (rhombencephalitis) was set up on the basis of further clinical course and positive blood cultures. Listerial rhombencephalitis should be kept ...
Source: Polish Journal of Neurology and Neurosurgery - January 10, 2017 Category: Neurosurgery Source Type: research

An unusual presentation of Listeria monocytogenes rhombencephalitis.
We describe a case of 52-year-old woman with a medical history of Crohn's disease presented abrupt fever, asymmetrical multiple cranial nerve palsies and focal neurological symptoms localized to the brainstem. The patient was initially diagnosed with ischaemic stroke, because of acute clinical course and results of neuroimaging. Cerebrospinal fluid analysis revealed mild infection with negative Gram staining and culture. Final diagnosis of Listeria monocytogenes brainstem infection (rhombencephalitis) was set up on the basis of further clinical course and positive blood cultures. Listerial rhombencephalitis should be kept ...
Source: Neurologia i Neurochirurgia Polska - January 9, 2017 Category: Neurology Authors: Acewicz A, Witkowski G, Rola R, Ryglewicz D, Sienkiewicz-Jarosz H Tags: Neurol Neurochir Pol Source Type: research

The Terrifying Way Not Sleeping Enough Actually Changes Your Gut
Studies link insufficient sleep to some pretty scary consequences, including an increased risk of stroke, heart disease, diabetes, obesity and even some cancers. Experts still don’t fully understand why not getting enough sleep is connected to all of these conditions, but new research published this month adds one piece to the puzzle: Not getting enough sleep may cause changes to gut bacteria that could fundamentally change our metabolism, affecting a host of bodily systems. Gut microbiota are the trillions of microorganisms living in our intestines that help keep our metabolism, immune system and othe...
Source: Science - The Huffington Post - December 23, 2016 Category: Science Source Type: news

Increasing comorbidity and health services utilization in older adults with prior stroke
Conclusions: Our findings demonstrate the importance of community-based patient-centered care strategies for stroke survivors that address their range of health needs and prevent more costly acute care use.
Source: Neurology - November 13, 2016 Category: Neurology Authors: Gruneir, A., Griffith, L. E., Fisher, K., Panjwani, D., Gandhi, S., Sheng, L., Patterson, C., Gafni, A., Ploeg, J., Markle-Reid, M. Tags: All Health Services Research, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Imparied retrobulbar blood flow and increased carotid IMT in patients with Crohn ’s disease
AbstractCrohn ’s Disease [CD] is one of the Inflammatory Bowel Diseases that are chronic relapsing inflammatory diseases. Despite the major affected organ is intestine in CD, extra intestinal organs and tissues including cardiovascular system are also affected. Several studies have demonstrated that CD patients may have a higher risk of advancing atherosclerosis. The microvascular endothelial dysfunction plays an essential role for developing coronary atherosclerosis. Microvascular structural abnormalities in the retinal circulation may predict macrovascular events such as stroke and coronary heart diseas e. In order to ...
Source: The International Journal of Cardiovascular Imaging - August 12, 2016 Category: Radiology Source Type: research

Acute Stroke in a Girl with an Absent Radial Pulse
A 13 year-old right-handed girl woke with left-sided tinnitus, left facial burning, slurred speech, and confusion. Past medical history included poorly controlled ulcerative colitis, von Willebrand’s disease type 2, and anemia [hemoglobin 9.2 g/dL; normal 11.2-14.8 g/dL]. Medications included mercaptopurine, mesalamine, and ferrous sulfate.
Source: Pediatric Neurology - June 9, 2016 Category: Neurology Authors: Shivani Ghoshal, Richard A. Bronen, Paul L. McCarthy, Salley G. Pels, Lauren A. Beslow Tags: Visual Diagnosis Source Type: research

Acute Stroke in a Girl With an Absent Radial Pulse
This 13-year-old right-handed girl awoke with left tinnitus, left facial burning, slurred speech, and confusion. Her past medical history included poorly controlled ulcerative colitis, von Willebrand disease type 2, and anemia (hemoglobin 9.2  g/dL; normal 11.2 to 14.8 g/dL). Medications included mercaptopurine, mesalamine, and ferrous sulfate.
Source: Pediatric Neurology - June 9, 2016 Category: Neurology Authors: Shivani Ghoshal, Richard A. Bronen, Paul L. McCarthy, Salley G. Pels, Lauren A. Beslow Tags: Visual Diagnosis Source Type: research

Health status of populations living in French overseas territories in 2012, compared with metropolitan France: An analysis of the national health insurance database.
CONCLUSION: This study highlights the utility of administrative database to compare and follow population health status considering healthcare use. Specific Public Health policies are justified for FOT, taking into account the specific context of each FOT, the necessity of prevention initiatives and screening to reduce the frequency of the chronic diseases. PMID: 27238162 [PubMed - as supplied by publisher]
Source: Revue d Epidemiologie et de Sante Publique - May 31, 2016 Category: Epidemiology Tags: Rev Epidemiol Sante Publique Source Type: research

Comment on: "measurement and clinical implications of choroidal thickness in patients with inflammatory bowel disease"
ABSTRACT Herpes zoster (HZ) corresponds to the reactivation of varicella zoster virus (VZV). Among adults, the ophthalmic division of the trigeminal nerve is one of the most common sites of involvement. Vasculopathy caused by HZ is associated with significant morbidity and mortality, affecting structures such as the brain, which can lead to stroke. In this review, we analyzed the epidemiological and clinical aspects of the vascular involvement of VZV, focusing on the peculiarities of its association with ocular HZ. A review of the available literature indicated that ocular involvement of HZ was a risk factor for vasculopat...
Source: Arquivos Brasileiros de Oftalmologia - May 24, 2016 Category: Opthalmology Source Type: research

Vitamin D Deficiency Is As Dangerous As Smoking
The advice you’re getting from your doctor, the TV and even the Surgeon General is so wrong, it’s scary. They’re all busy telling you to stay out of the sun. But Swedish researchers recently discovered that nonsmokers who avoid the sun have a life expectancy similar to smokers who spend a lot of time in the sun. Staying out of the sun is as dangerous as smoking.1 It doesn’t surprise me. I tell all my patients sunlight exposure is essential to our health because it is the best source of vitamin D… possibly the most important nutrient we know of. Mainstream medicine still doesn’t recognize th...
Source: Al Sears, MD Natural Remedies - May 19, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Health Source Type: news

Pharmacological Prophylaxis for Venous Thromboembolism Among Hospitalized Patients With Acute Medical Illness: An Electronic Medical Records Study
The objectives of this study were to examine pharmacological prophylaxis against VTE among hospitalized medically ill patients and to assess demographic and clinical correlates related to VTE prophylaxis. A retrospective (1999–2010) electronic medical records study included patients aged 40 years and older hospitalized for at least 3 days, with significant medical illness or with a VTE hospitalization 30–365 days before admission. Each patient's first qualifying hospitalization was analyzed. Exclusions were if VTE treatment was started within 1 day of admission, or if warfarin (and not heparin or enoxaparin) was used. ...
Source: American Journal of Therapeutics - March 1, 2016 Category: Drugs & Pharmacology Tags: Original Articles Source Type: research

Association Between Long-Term Lipid Profiles and Disease Severity in a Large Cohort of Patients with Inflammatory Bowel Disease
Conclusions Low total cholesterol and high triglyceride levels are more frequent in IBD patients (in particular CD) compared to healthy controls and are independently associated with more severe disease.
Source: Digestive Diseases and Sciences - February 20, 2016 Category: Gastroenterology Source Type: research

Thalidomide Analogs that Inhibit Inflammation and Angiogenesis
Thalidomide and its close analogs (lenalidomide and pomalidomide) are widely used to treat a variety of diseases, such as multiple myeloma and other cancers as well as the symptoms of several inflammatory disorders. However, thalidomide is known for its teratogenic adverse effects when first clinically introduced in the 1950s, and is associated with drowsiness and peripheral neuropathy. Hence, there is intense interest to synthesize, identify and develop safer analogs.Researchers at the National Institute on Aging’s Drug Design and Development Section synthesized novel thalidomide analogs that demonstrate clinical potent...
Source: NIH OTT Licensing Opportunities - December 23, 2015 Category: Research Authors: admin Source Type: research

Potential clinical applications of adult human mesenchymal stem cell (Prochymal®) therapy.
Authors: Patel AN, Genovese J Abstract In vitro, in vivo animal, and human clinical data show a broad field of application for mesenchymal stem cells (MSCs). There is overwhelming evidence of the usefulness of MSCs in regenerative medicine, tissue engineering, and immune therapy. At present, there are a significant number of clinical trials exploring the use of MSCs for the treatment of various diseases, including myocardial infarction and stroke, in which oxygen suppression causes widespread cell death, and others with clear involvement of the immune system, such as graft-versus-host disease, Crohn's disease, and ...
Source: Stem Cells and Cloning: Advances and Applications - December 1, 2015 Category: Stem Cells Tags: Stem Cells Cloning Source Type: research