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Condition: Inflammatory Bowel Disease

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Total 222 results found since Jan 2013.

Young-onset stroke complicating ulcerative colitis
Pract Neurol. 2022 Jan 7:practneurol-2021-003106. doi: 10.1136/practneurol-2021-003106. Online ahead of print.ABSTRACTA 16-year-old girl developed a proximal occlusion of the right middle cerebral artery during a flare-up of acute ulcerative colitis. Although mechanical thrombectomy led to successful middle cerebral artery recanalisation, she required an immediate second thrombectomy due to reocclusion of the same arterial segment. She developed a second ischaemic event 7 days later despite intravenous heparin infusion, later switched to low-molecular-weight heparin, and a third event after 3 days despite the addition of a...
Source: Practical Neurology - January 8, 2022 Category: Neurology Authors: Su Yin Lim Mohamed Sayed Soma Banerjee Neil Rane Dheeraj Kalladka Source Type: research

Prevalence and Predictors of Stroke in Patients with Crohn's Disease: A Nationwide Study
CONCLUSION: A subset of traditional stroke risk factors are associated with IS in patients with CD. CD patients with these conditions could be targeted for vascular risk reduction and surveillance.PMID:34923435 | DOI:10.1016/j.jstrokecerebrovasdis.2021.106258
Source: Atherosclerosis - December 19, 2021 Category: Cardiology Authors: Satvir Saggi Alain Lekoubou Bruce Ovbiagele Source Type: research

Risk of Thromboembolic Events and Associated Healthcare Costs in Patients with Inflammatory Bowel Disease
ConclusionsPatients with IBD experienced greater rates of DVT and PE compared to patients without IMD; this elevated risk was associated with a substantial economic burden.
Source: Advances in Therapy - December 7, 2021 Category: Drugs & Pharmacology Source Type: research

Tumor necrosis factor inhibitor (TNFi) persistence and reasons for discontinuation in a predominantly male cohort with axial spondyloarthritis
Rheumatol Int. 2021 Nov 1. doi: 10.1007/s00296-021-05024-w. Online ahead of print.ABSTRACTAlthough tumor necrosis factor inhibitors (TNFi) have favorably altered the treatment landscape for patients with axial spondyloarthritis (axSpA), there is limited data regarding TNFi persistence and reasons for discontinuation. This is an observational time-to-event study utilizing data collected for a prospective multiple-disease registry of US Veterans with axSpA treated with TNFi therapies and recruited over a 10 year period. Clinical, serological, and comorbid parameters were collected. Corporate Data Warehouse Pharmacy files pro...
Source: Pain Physician - November 1, 2021 Category: Anesthesiology Authors: Delamo I Bekele Elizabeth Cheng Andreas Reimold Christian Geier Kavya Ganuthula Jessica A Walsh Daniel O Clegg Maureen Dubreuil Prashant Kaushik Bernard Ng Elizabeth Chang Ryan Duong Jina Park Gail S Kerr Source Type: research

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Indolent nonendemic central nervous system histoplasmosis presenting as an isolated intramedullary enhancing spinal cord lesion
CONCLUSION: Disseminated histoplasmosis should be considered in granulomatous disease, even if the patient resides in a nonendemic region. Furthermore, clinicians should be mindful that CNS histoplasmosis may present in an atypical fashion.PMID:34513158 | PMC:PMC8422457 | DOI:10.25259/SNI_345_2021
Source: Surgical Neurology International - September 13, 2021 Category: Neurosurgery Authors: Matthew J Recker Steven B Housley Lindsay J Lipinski Source Type: research