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Condition: Inflammatory Bowel Disease

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Total 222 results found since Jan 2013.

Identification of healthspan-promoting genes in Caenorhabditis elegans based on a human GWAS study
Biogerontology. 2022 Jun 24. doi: 10.1007/s10522-022-09969-8. Online ahead of print.ABSTRACTTo find drivers of healthy ageing, a genome-wide association study (GWAS) was performed in healthy and unhealthy older individuals. Healthy individuals were defined as free from cardiovascular disease, stroke, heart failure, major adverse cardiovascular event, diabetes, dementia, cancer, chronic obstructive pulmonary disease (COPD), asthma, rheumatism, Crohn's disease, malabsorption or kidney disease. Six single nucleotide polymorphisms (SNPs) with unknown function associated with ten human genes were identified as candidate healths...
Source: Biogerontology - June 24, 2022 Category: Geriatrics Authors: Nadine Saul Ineke Dhondt Mikko Kuokkanen Markus Perola Clara Verschuuren Brecht Wouters Henrik von Chrzanowski Winnok H De Vos Liesbet Temmerman Walter Luyten Aleksandra Ze čić Tim Loier Christian Schmitz-Linneweber Bart P Braeckman Source Type: research

Uncovering the Mechanism of the Xingnaojing Injection against Ischemic Stroke Using a Combined Network Pharmacology Approach and Gut Microbiota Analysis
CONCLUSION: IS causes dysbiosis of some specific bacteria in the gut microbiota. XNJ is an effective treatment for IS, and its mechanism was related to improving intestinal barrier function and regulating intestinal flora and SCFAs. Network pharmacology revealed that XNJ acts through multiple targets and multiple pathways.PMID:35646156 | PMC:PMC9142292 | DOI:10.1155/2022/5886698
Source: Evidence-based Complementary and Alternative Medicine - June 1, 2022 Category: Complementary Medicine Authors: Ganlu Liu Jingfeng Lin Lina Zhang Qiang Gao Zhenyi Wang Ze Chang Ying Gao Dayong Ma Zhenyun Han Source Type: research

Presence of Comorbidities Associated with Severe Coronavirus Infection in Patients with Inflammatory Bowel Disease
ConclusionMany non-IBD comorbidities are associated with a two to threefold increased risk of COVID-19 hospitalization or death among patients with IBD. These data can be used to risk-stratify and guide treatment and lifestyle decisions during the ongoing pandemic.
Source: Digestive Diseases and Sciences - April 1, 2022 Category: Gastroenterology Source Type: research

Genetically Predicted Frailty Index and Risk of Stroke and Alzheimer's Disease
CONCLUSIONS: The MR study suggested that genetically predicted FI may be associated with an increased risk of any stroke. Subgroup analysis indicated a suggestive association between genetically predicated FI and the risk of LAS. The underlying mechanisms need further warranted.PMID:35318774 | DOI:10.1111/ene.15332
Source: Atherosclerosis - March 23, 2022 Category: Cardiology Authors: Weishi Liu Luyang Zhang Hui Fang Yuan Gao Kai Liu Shen Li Hongbing Liu Xin Wang Chen Liu Bo Song Zongping Xia Yuming Xu Source Type: research

Cardiovascular comorbidities in psoriasis (Review)
Exp Ther Med. 2022 Feb;23(2):152. doi: 10.3892/etm.2021.11075. Epub 2021 Dec 17.ABSTRACTLong considered a skin-limited condition, psoriasis is currently defined as a chronic, immune-mediated inflammatory disease, presenting, besides the skin changes, important systemic manifestations, the most common being: psoriatic arthritis, cardiovascular disease, metabolic syndrome, diabetes, inflammatory bowel disease and nonalcoholic steatohepatitis. It is a disease with a strong psycho-emotional and social impact, both through skin changes such as pruritic, scaly erythematous plaques, and through the association of comorbidities th...
Source: Experimental and Therapeutic Medicine - January 24, 2022 Category: General Medicine Authors: Daciana Elena Branisteanu Alin Codrut Nicolescu Daniel Constantin Branisteanu Catalina Ioana Branisteanu Andreea Corina Dragoi Camelia Margareta Bogdanici Mihaela Paula Toader Andreea Lorena Tucaliuc Andreea Dimitriu Doru Daogaru Ruxandra Angela Pirvulesc Source Type: research

Burden of illness of osteoporotic fractures compared to other serious diseases among ibd patients
Inflammatory bowel disease (IBD) patients are off and on treated with steroids which is associated with increased risk of osteoporosis and fragility fractures. We conducted an analysis to study the burden of osteoporotic fractures compared to acute myocardial infarction (AMI) or stroke in hospitalized patients with IBD.
Source: Gastroenterology - January 20, 2022 Category: Gastroenterology Authors: Raseen Tariq, Muhammad Waqas Tahir, Zoya Tahir, Faizan Zaheer, Abdul Wahab Tags: Disease Complications Source Type: research