Anterior segment optical coherence tomography in pupillary seclusion diagnosis and follow-up
ABSTRACT Age-related macular degeneration is the leading cause of vision loss in elderly individuals, as well as a medical and socio-economic challenge. The treatment of dry age-related macular degeneration is based on vitamin supplementation. New treatment studies are focused on preventing the progression of degeneration and repopulating the atrophic macula. Recently, research on the treatment of neovascular age-related macular degeneration experienced a breakthrough with the advent of anti-vascular endothelial growth factor inhibitors. Nevertheless, despite the fact that ranibizumab, aflibercept, and bevacizumab are effe...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Utilization of the philtral pressure technique as an efficacious measure to prevent coronavirus transmission through sneezing
ABSTRACT Age-related macular degeneration is the leading cause of vision loss in elderly individuals, as well as a medical and socio-economic challenge. The treatment of dry age-related macular degeneration is based on vitamin supplementation. New treatment studies are focused on preventing the progression of degeneration and repopulating the atrophic macula. Recently, research on the treatment of neovascular age-related macular degeneration experienced a breakthrough with the advent of anti-vascular endothelial growth factor inhibitors. Nevertheless, despite the fact that ranibizumab, aflibercept, and bevacizumab are effe...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Portable devices in ophthalmology
ABSTRACT Age-related macular degeneration is the leading cause of vision loss in elderly individuals, as well as a medical and socio-economic challenge. The treatment of dry age-related macular degeneration is based on vitamin supplementation. New treatment studies are focused on preventing the progression of degeneration and repopulating the atrophic macula. Recently, research on the treatment of neovascular age-related macular degeneration experienced a breakthrough with the advent of anti-vascular endothelial growth factor inhibitors. Nevertheless, despite the fact that ranibizumab, aflibercept, and bevacizumab are effe...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Could we accidentally measure visual acuity low in the time of the COVID-19 pandemic?
ABSTRACT Age-related macular degeneration is the leading cause of vision loss in elderly individuals, as well as a medical and socio-economic challenge. The treatment of dry age-related macular degeneration is based on vitamin supplementation. New treatment studies are focused on preventing the progression of degeneration and repopulating the atrophic macula. Recently, research on the treatment of neovascular age-related macular degeneration experienced a breakthrough with the advent of anti-vascular endothelial growth factor inhibitors. Nevertheless, despite the fact that ranibizumab, aflibercept, and bevacizumab are effe...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Localized retinal nerve fiber layer defect in patients with COVID-19
ABSTRACT Age-related macular degeneration is the leading cause of vision loss in elderly individuals, as well as a medical and socio-economic challenge. The treatment of dry age-related macular degeneration is based on vitamin supplementation. New treatment studies are focused on preventing the progression of degeneration and repopulating the atrophic macula. Recently, research on the treatment of neovascular age-related macular degeneration experienced a breakthrough with the advent of anti-vascular endothelial growth factor inhibitors. Nevertheless, despite the fact that ranibizumab, aflibercept, and bevacizumab are effe...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Age-related macular degeneration: a review of current therapies and new treatments
ABSTRACT Age-related macular degeneration is the leading cause of vision loss in elderly individuals, as well as a medical and socio-economic challenge. The treatment of dry age-related macular degeneration is based on vitamin supplementation. New treatment studies are focused on preventing the progression of degeneration and repopulating the atrophic macula. Recently, research on the treatment of neovascular age-related macular degeneration experienced a breakthrough with the advent of anti-vascular endothelial growth factor inhibitors. Nevertheless, despite the fact that ranibizumab, aflibercept, and bevacizumab are effe...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Trocar-assisted, flanged haptics, sutureless intrascleral fixated intraocular lens implantation combined with Descemet membrane endothelial keratoplasty
This article reports a combined technique of sutureless intrascleral fixated intraocular lens implantation and Descemet membrane endothelial keratoplasty in a patient with anterior pseudophakic bullous keratopathy. Two scleral tunnels were created, corneal incisions were made, and a foldable intraocular lens was cut and removed from the anterior chamber. After performing anterior vitrectomy, a 3-piece foldable intraocular lens was implanted into the anterior chamber. One of the intraocular lens haptics was grasped with a forceps and pulled out from the scleral tunnel. Then, the end of the haptic was cauterized. Similar man...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Retinal ischemia following mandible tumor treatment with steroid injection
We report a case of retinal arteriolar ischemic disease following central giant cell granuloma management with local injected corticosteroids.RESUMO O granuloma central de c élulas gigantes é um tumor ósseo raro que afeta pacientes jovens com comprometimento anatômico e funcional da maxila e mandíbula. A terapia com injeção de esteroides constitui uma modalidade de tratamento menos invasiva para o controle da doença em casos selecionados. A isquemia retiniana é uma complicação relatada em vários procedimentos médicos, incluindo interv...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Corneal suture for acute corneal hydrops secondary to post-LASIK ectasia: a case report
In this report, we describe a case of corneal ectasia after laser-assisted in situ keratomileusis), which progressed with acute hydrops and aqueous leakage and required a suture for correction.RESUMO A ectasia corneana é uma das principais complicações das cirurgias refrativas. Neste caso, descrevemos um caso de ectasia corneana induzida por laser-assisted in situ keratomileusis, que evoluiu com hidrópsia aguda e extravasamento de humor aquoso, necessitando de sutura corneana. (Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Angioid streaks and optic disc drusen in cherubism: a case report
ABSTRACT A 65-year-old female patient was referred to our hospital for evaluation for cataract surgery. Her past medical history included corrective jaw surgeries for facial deformities that developed during infancy and persisted through early adulthood. A complete ophthalmological examination revealed bilateral angioid streaks, drusen in both optic disc areas, and a subretinal neovascular membrane in the left macula. Genetic analysis revealed a mutation in the SH3BP2 gene compatible with the diagnosis of cherubism. Clinical and laboratory evaluation revealed no additional systemic disorders. Cherubism is a rare disease ch...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

ETDRS panretinal photocoagulation combined with intravitreal ranibizumab versus PASCAL panretinal photocoagulation with intravitreal ranibizumab versus intravitreal ranibizumab alone for the treatment of proliferative diabetic retinopathy
ABSTRACT Purpose: To compare visual acuity, macular thickness, and the area of active neovascularization based on fluorescein angiography outcomes associated with standard single-spot panretinal photocoagulation in the Early Treatment Diabetic Retinopathy Study (ETDRS) pattern combined with intravitreal ranibizumab injection versus multiple-spot full scatter (PASCAL) panretinal photocoagulation combined with intravitreal ranibizumab injection versus intravitreal injection alone in patients with proliferative diabetic retinopathy. Methods: Patients with proliferative diabetic retinopathy and no prior laser treatment were ra...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Evaluation of the retinal vasculature of patients with branch retinal vein occlusion using optical coherence tomography angiography
ABSTRACT Purpose: To evaluate vascular density in super ­ficial and deep capillary plexuses of the retina, measured using optical coherence tomography angiography in patients with branch retinal vein occlusion. Affected eyes were compared with the contralateral eye of the same patient and both were compared with normal eyes. Methods: A cross-sectional study including 16 previously untreated patients with branch retinal vein occlusion. Patients with poor quality examinations, bilateral disease, high refractive error, or any other retinal or choroidal disease were excluded. A total of 31 patients without eye disease were...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Evaluation of the tear parameters of ovulation induction patients in a short time period with anterior segment optical coherence tomography
ABSTRACT Purpose: The effects of sex steroid hormones on tearparameters are known. Theaim of this studywas to examine the effects on tear parameters during exposure to high-dose sex steroids in a short period of time. Methods: Forty patients who were admitted to the infertility clinic of our hospital and planned to undergo ovulation induction with exogenous gonadotropins were included in our study. Prior tothe initiation of ovulation induction, the basal levels of estradiol were measured on day 3 of the menstrual cycle and ophthalmologic examinations were performed by the ophthalmology department of our hospital. The estra...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Novel low-cost approach to the treatment of ocular surface squamous neoplasia using pattern scanning laser photocoagulation
Conclusion: Short-term results of the laser photocoagulation approach for the treatment of ocular surface squamous neoplasia conjunctival lesions were favorable, with a 74% success rate observed in immunocompetent patients. This novel strategy is a less resource-intensive alternative that could demonstrate its usefulness in settings with shortages in operating rooms and in recurrent cases. Studies with longer follow-ups and larger sample sizes are warranted to confirm our findings and evaluate the effectiveness of laser treatment in association with topical chemotherapy.RESUMO Objetivo: Avaliar a seguran ça e o efei...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Association between disorganization of the retinal inner layers and capillary nonperfusion area in patients with retinal vein occlusion
ABSTRACT Purpose: To determine the correlation between the extent of disorganization of the retinal inner layers (a parameter of spectral domain optical coherence tomography) and optical coherence tomography angiography parameters in eyes with center-involved macular edema associated with retinal vein occlusion. Methods: This retrospective observational study included 34 eyes of 34 patients with newly diagnosed macular edema associated with retinal vein occlusion and evidence of center-involved macular edema. Optical coherence tomography angiography and spectral domain optical coherence tomography were evaluated after reso...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Swept-source optical coherence tomography findings in premature children with a history of retinopathy of prematurity at 5 years of age
Conclusions: Visual functional outcomes were better in term-born healthy children compared with those noted in children with a history of treated retinopathy of prematurity and spontaneously regressed retinopathy of prematurity. Laser treatment exerted a signifi ­cant effect on central foveal thickness in premature children at the age of 5 years, as revealed by swept-source optical coherence tomography.RESUMO Objetivo: Comparar a espessura central foveal, a da camada de fibras nervosas da retina e a da cor óide subfoveal através da tomografia de coerência óptica swept-source em criança...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Solitary fibrofolliculoma: a retrospective case series review over 18 years
Conclusion: Solitary fibrofolliculoma is a rare lesion, seldom affecting the eyelids. We reported 11 cases, and the third case reported thus far in the literature affecting the lids. Diagnosis may be easily mis sed due to the nonspecific symptoms and clinical appearance. Therefore, it is necessary to perform excisional biopsy and histological examination for the recognition of this lesion.RESUMO Objetivo: o objetivo deste estudo foi relatar uma s érie de casos de fibrofoliculoma solitário, uma lesão raramente observada nas pálpebras. Demografia, bem como aspectos clínicos e histoló...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Impact of different clear corneal incision sizes on anterior corneal aberration for cataract surgery
ABSTRACT Purpose: To investigate the impact of different sizes of steep meridian clear corneal incisions for phacoemul sification on anterior corneal higher-order aberrations. Methods: Medical records of patients who underwent 2.2-mm coaxial micro-incision cataract surgery or 2.75-mm coaxial small-incision cataract surgery were retrospectively reviewed. Only patients with preexisting anterior corneal astigmatism
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Optical coherence tomography angiography findings in patients with Alport syndrome
Conclusions: In patients with Alport syndrome, the inner retinal layers suffer changes due to type IV collagen mutations. Optical coherence tomography angiography makes it possible to visualize and document thes e findings, making it a useful tool in the detection of early retinal findings associated with Alport syndrome.RESUMO Objetivos: Descrever os achados na angiografia por tomografia de coer ência óptica associada à síndrome de Alport. Métodos: Estudo descritivo de um serviço de referência em Oftalmologia (Hospital Evangélico de Vila Velha, Brasil). Os pacientes di...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Characterization and distribution of viridans group streptococci isolated from infectious endophthalmitis and keratitis
Conclusions: The distribution of alpha-hemolytic streptococci in ocular infections suggested the presence of a species-specific tissue tropism. The prognoses of patients with ocular streptococcal infections were highly unfavorable, and antibiotic resistance did not contribute to the unfavorable clinical progressions and poor outcomes.RESUMO Objetivo: O objetivo deste estudo foi caracterizar os estreptococos alfa-hemol íticos isolados de endoftalmite infecciosa e ceratite e determinar sua distribuição. Métodos: A amostra incluiu 27 e 35 isolados não-duplicados de estreptococos alfa-hemol&i...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Ophthalmology Academic Leagues: making an impact on Medical Education
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Different clinical manifestations of ocular sporotrichosis in the same patient: an alert to ophthalmologists in nonendemic areas
We present here a critical review of the concepts associated with corneal blindness that need to be considered when planning strategies to prevent and treat corneal blindness worldwide (to be able to leave Plato ’ s cave, where corneal blindness is encaged.RESUMO O problema da defici ência visual e da cegueira corneal abrange o mundo todo e corresponde à quarta causa de cegueira e deficiência visual, com acometimento estimado de mais de 16 milhões de pessoas. A associação com várias doenças endêmicas, como cegueira infantil, trauma, ceratites infecciosas (in...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Ten years after an outbreak of Fusarium endophthalmitis following cataract surgery
We present here a critical review of the concepts associated with corneal blindness that need to be considered when planning strategies to prevent and treat corneal blindness worldwide (to be able to leave Plato ’ s cave, where corneal blindness is encaged.RESUMO O problema da defici ência visual e da cegueira corneal abrange o mundo todo e corresponde à quarta causa de cegueira e deficiência visual, com acometimento estimado de mais de 16 milhões de pessoas. A associação com várias doenças endêmicas, como cegueira infantil, trauma, ceratites infecciosas (in...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Floppy capsule appearance during phacoemulsification with mannitol in eyes with angle closure glaucoma
We present here a critical review of the concepts associated with corneal blindness that need to be considered when planning strategies to prevent and treat corneal blindness worldwide (to be able to leave Plato ’ s cave, where corneal blindness is encaged.RESUMO O problema da defici ência visual e da cegueira corneal abrange o mundo todo e corresponde à quarta causa de cegueira e deficiência visual, com acometimento estimado de mais de 16 milhões de pessoas. A associação com várias doenças endêmicas, como cegueira infantil, trauma, ceratites infecciosas (in...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Response to the editorial titled “Public health strategy vs. golden standard for ocular cancer care in Brazil” by Neto, RB
We present here a critical review of the concepts associated with corneal blindness that need to be considered when planning strategies to prevent and treat corneal blindness worldwide (to be able to leave Plato ’ s cave, where corneal blindness is encaged.RESUMO O problema da defici ência visual e da cegueira corneal abrange o mundo todo e corresponde à quarta causa de cegueira e deficiência visual, com acometimento estimado de mais de 16 milhões de pessoas. A associação com várias doenças endêmicas, como cegueira infantil, trauma, ceratites infecciosas (in...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

NEI VFQ-25 questionnaire is an excellent option to evaluate the quality of life of Brazilian patients with cataract?
We present here a critical review of the concepts associated with corneal blindness that need to be considered when planning strategies to prevent and treat corneal blindness worldwide (to be able to leave Plato ’ s cave, where corneal blindness is encaged.RESUMO O problema da defici ência visual e da cegueira corneal abrange o mundo todo e corresponde à quarta causa de cegueira e deficiência visual, com acometimento estimado de mais de 16 milhões de pessoas. A associação com várias doenças endêmicas, como cegueira infantil, trauma, ceratites infecciosas (in...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Corneal blindness in Plato’s cave: the acting forces to prevent and revert corneal opacity. Part I: epidemiology and new physiopathological concepts
We present here a critical review of the concepts associated with corneal blindness that need to be considered when planning strategies to prevent and treat corneal blindness worldwide (to be able to leave Plato ’ s cave, where corneal blindness is encaged.RESUMO O problema da defici ência visual e da cegueira corneal abrange o mundo todo e corresponde à quarta causa de cegueira e deficiência visual, com acometimento estimado de mais de 16 milhões de pessoas. A associação com várias doenças endêmicas, como cegueira infantil, trauma, ceratites infecciosas (in...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

The Canabrava Ring, an open ring-shaped pupil expander for cataract surgery associated with iris colobomata: a case report
In this report, we describe a new pupil expander device that was used to obtain adequate pupil dilation and centering in a patient with an iris coloboma. Specifically, we describe the case of a patient with an iris coloboma; a Malyugin ring was inserted to facilitate dilation during phacoemulsifi ­cation surgery. One of the scrolls did not engage which resulted in an uneven distribution of forces and an eccentric pupil. A Canabrava Ring was then implanted that promoted effective pupillary dilation and remained stable and effective throughout the surgical procedure.RESUMO Neste relato, descrevemos um novo dispositivo ex...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Descemet’s membrane endothelial keratoplasty for acute corneal hydrops: a case report
ABSTRACT Here, we describe the result of a Descemet ’ s membrane endothelial keratoplasty for acute corneal hydrops in a 45-year-old female with keratoconus, who presented with severe visual loss in her OS. The patient ’ s best-corrected visual acuity was 20/80 in the right eye and hand motion in the OS. Slit-lamp examination revealed an extensive tear of the Descemet ’ s membrane and stromal corneal edema in the OS. We opted for Descemet membrane endothelial keratoplasty. Twelve months postoperatively, the patient had a best-corrected visual acuity of 20/50 in the OS.RESUMO Trata-se de uma paciente do se...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Solitary circumscribed neuroma of the conjunctiva: Differential diagnosis from neurofibroma is a must?
ABSTRACT A 42-year-old male presented with a 4-week history of a mass in the right inferior palpebral conjunctiva close to the punctum. An excisional biopsy of the lesion and histopathological examination revealed that the mass was composed of Schwann cells with thin conical nuclei, fine chromatin, and unnoticeable nucleoli. Immunohistochemically, the spindle cells were diffusely and strongly positive for S100 protein. Neurofilament immunostaining was also positive, which highlighted axons. In light of these findings, the tumor was diagnosed as solitary circumscribed neuroma. A comprehensive evaluation for multiple endocri...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Complex strabismus: a case report of hypoplasia of the third cranial nerve with an unusual clinical presentation
We describe here the surgical management of a 16-year-old boy who presented with complex strabismus secondary to hypoplasia of the third cranial nerve and aberrant innervation of the upper ipsilateral eyelid.RESUMO Os dist úrbios de inervação craniana congênita en­globam um grupo de síndromes associadas a estrabismos complexos, que se apresentam como oftalmoplegia congênita e não progressiva e são frequentemente herdadas. Os defeitos dos genes estão associados a erros no desenvolvimento ou direcionamento axo nal dos motoneurônios, e erros no direcioname...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Ocular blood flow and choroidal thickness changes after carotid artery stenting
Conclusions: In patients with carotid artery stenosis, the subfoveal choroid is thinner than that in healthy controls. The subfoveal choroidal thickness increases after carotid artery stenting. Carotid artery stenting treatment increases the blood flow to the posterior ciliary artery, and the preprocedural subfoveal choroidal thickness may be a good predictor of the postprocedural peak systolic velocity of the posterior ciliary artery.RESUMO Objetivos: Avaliar altera ções no fluxo sanguíneo ocular e na espessura da coroide subfoveal em pacientes com estenose sintomática da artéria car&oac...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Optical coherence tomography detection of changes in inner retinal and choroidal thicknesses in patients with early retinitis pigmentosa
Conclusions: The choroid was mildly affected in our patients with early retinitis pigmentosa. The tendency toward significance in the inner retina was possibly caused by a good visual acuity.RESUMO Objetivo: Avaliar as espessuras internas da retina e da coroide em pacientes com retinite pigmentosa precoce. M étodos: Foram analisadas imagens de tomografia de coerência óptica de domínio espectral de 35 pacientes com retinite pigmentosa e 40 indivíduos saudáveis. Medimos a espessura do complexo de células maculares e ganglionares. Realizamos medições da espessura d...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Immune modulator therapy compared with vitrectomy for management of complicated intermediate uveitis: a prospective, randomized clinical study
Conclusions: Pars plana vitrectomy and immune modulator therapy resulted in significant improvement in visual function in patients with persistent inflammation secondary to chronic intermediate uveitis. Despite this success, there remains a need for the determination of optimal indications for the use of each modality. Immune modulator therapy was successful for the treatment of diffuse macular edema associated with chronic intermediate uveitis, whereas pars plana vitrectomy was not.RESUMO Objetivo: Comparar os benef ícios e efeitos co laterais da vitrectomia via pars plana com os da terapia imunomo duladora sist&ec...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Three versus five intravitreal aflibercept injections as the initial loading phase in the treatment of diabetic macular edema: one-year results
ABSTRACT Purpose: To compare the efficacy of three initial monthly intravitreal aflibercept injections followed by pro re nata (3+PRN) dosing versus five initial monthly intravitreal aflibercept injections followed by pro re nata (5+PRN) dosing in patients with diabetic macular edema. Methods: A total of 60 treatment-na ïve patients with macular edema who underwent intravitreal aflibercept injections (2 mg/0.05 mL) with at least one year of follow-up were analyzed in this retrospective and comparative study. The patients were divided into two groups according to the number of intravitreal aflibercept injections ad min...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Ganglion cell layer thinning in diabetic patients without retinopathy: related or unrelated to total macular thickness?
Conclusions: Mean ganglion cell layer thickness was not lower in diabetic patients without retinopathy than in non-diabetic patients. Moreover, it exhibited a substantial correlation with total macular thickness. Parafoveal vessel density decreased before ganglion cell layer thinning was observed.RESUMO Objetivo: Pode ocorrer redu ção da espessura da camada de células ganglionares em pacientes diabéticos sem retinopatia. As relações desse achado pré-clínico com a espessura da retina ou a densidade reduzida de vasos parafoveais não foram estabelecidas. Este estu...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Inner retinal thickness and optic disc measurements in obese children and adolescents
Conclusion: Compared to healthy children, obese children had greater binocular retinal nerve fiber layer thickness asymmetry and thinner retinal nerve fiber and ganglion cell-inner plexiform layers in several sectors. Blood lipid levels were not associated with retinal thickness or optic disc parameters in obese children.RESUMO Objetivo: O objetivo deste estudo foi avaliar os par âmetros da cabeça do nervo óptico e a espessura da camada interna da retina em crianças e adolescentes obesos. Métodos: Quarenta e um olhos de 41 participantes pediátricos obesos e 41 olhos de 41 controles ...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Aqueous humor heat-shock protein 70, periostin, and irisin levels in patients with pseudoexfoliation syndrome
We examined 31 eyes of 31 patients with pseudoexfoliation and cataract (without glaucoma) and 30 eyes of 30 patients with cataract. We collected aqueous humor samples from all patients at the time of cataract surgery through a limbal paracentesis via a 25-gauge cannula mounted on a tuberculin syringe that received 100 to 150 µL of aqueous humor. We measured levels of aqueous humor Heat shock protein 70, periostin, and irisin using enzyme-linked immunosorbent assay methods. Results: The age (p=0.221) and gender (p=0.530) means were similar between the pseudoexfoliation and control groups. The mean Heat shock protein 7...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Changes in the ganglion cell complex thickness after anti-VEGF treatment for diabetic macular edema
ABSTRACT Purpose: To assess tomographic ganglion cell complex changes in patients with diabetic macular edema treated with intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF). Methods: We analyzed data from 35 eyes of 35 previously untreated patients in whom diabetic macular edema improved after three loading doses of anti-VEGF injection and who did not receive repeated injections. We recorded spectral domain-optical coherence tomography assessments of ganglion cell complex and central macular thickness at baseline and monthly for three months, and on the sixth and ninth month after treatment. We...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

A theoretical model for graft punch size calculations to prevent Descemet’s membrane folds following deep anterior lamellar keratoplasty
Conclusion: Adjustment of donor graft size based on the calculated arc diameter of the recipient bed reduced the development of Descemet ’ s membrane folds after deep anterior lamellar keratoplasty in steep corneas.RESUMO Objetivo: O comprimento da membrana de Descemet e o tamanho do enxerto doador na ceratoplastia lamelar anterior profunda n ão coincidem em córneas muito íngremes, o que pode levar às dobras da membrana de Descemet. O objetivo deste estudo é estabelecer um modelo teórico para cálculo do tamanho do enxerto para ceratoplastia lamelar anterior profunda e ...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Surgical results regarding the correction of macular hole with and without face-down posturing using 25% SF6 gas: a retrospective case series
Conclusion: Our results suggest that macular hole surgery with the use of short duration gas (SF6) is safe and effective and that maintaining a postural orientation of nonface-down posturing is also safe. However, these recommendations should be assessed further in a prospective and randomized study to comprehensively delineate the associated benefits and risks.RESUMO Objetivos: Comparar as taxas de sucesso anat ômico da vitrectomia e tamponamento de gás SF6 na cirurgia de buraco macular com e sem a postura pronada pós-operatória. Métodos: Foi realizado um estudo observacional, longitudina...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

2020 and now: what has been accomplished in blindness prevention and what is next?
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Biomechanics in DALK: Big bubble vs Manual lamellar dissection
ABSTRACT The approach to any refractive condition of the eye with regular astigmatism is more complicated than that for myopia or hyperopia alone. It requires familiarity with the complex images collectively identified as Sturm ’ s conoid. Fortunately, only three of those play a critical role in the interpretation of ametropia with astigmatism. This manuscript discusses a prescription strategy for ametropias associated with regular astigmatism evolved from those three key images.RESUMO A abordagem de qualquer condi ção refrativa do olho com astigmatismo regular é mais complicada do que a da miopi...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

Missed opportunities on retinopathy of prematurity: the urgency of doing more
ABSTRACT The approach to any refractive condition of the eye with regular astigmatism is more complicated than that for myopia or hyperopia alone. It requires familiarity with the complex images collectively identified as Sturm ’ s conoid. Fortunately, only three of those play a critical role in the interpretation of ametropia with astigmatism. This manuscript discusses a prescription strategy for ametropias associated with regular astigmatism evolved from those three key images.RESUMO A abordagem de qualquer condi ção refrativa do olho com astigmatismo regular é mais complicada do que a da miopi...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

A warning against associating doxycycline with isotretinoin
ABSTRACT The approach to any refractive condition of the eye with regular astigmatism is more complicated than that for myopia or hyperopia alone. It requires familiarity with the complex images collectively identified as Sturm ’ s conoid. Fortunately, only three of those play a critical role in the interpretation of ametropia with astigmatism. This manuscript discusses a prescription strategy for ametropias associated with regular astigmatism evolved from those three key images.RESUMO A abordagem de qualquer condi ção refrativa do olho com astigmatismo regular é mais complicada do que a da miopi...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

Bilateral Pseudomonas endophthalmitis after immediately sequential bilateral cataract surgery: primum non nocere
ABSTRACT The approach to any refractive condition of the eye with regular astigmatism is more complicated than that for myopia or hyperopia alone. It requires familiarity with the complex images collectively identified as Sturm ’ s conoid. Fortunately, only three of those play a critical role in the interpretation of ametropia with astigmatism. This manuscript discusses a prescription strategy for ametropias associated with regular astigmatism evolved from those three key images.RESUMO A abordagem de qualquer condi ção refrativa do olho com astigmatismo regular é mais complicada do que a da miopi...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

Prescription for astigmatic ametropia revisited
ABSTRACT The approach to any refractive condition of the eye with regular astigmatism is more complicated than that for myopia or hyperopia alone. It requires familiarity with the complex images collectively identified as Sturm ’ s conoid. Fortunately, only three of those play a critical role in the interpretation of ametropia with astigmatism. This manuscript discusses a prescription strategy for ametropias associated with regular astigmatism evolved from those three key images.RESUMO A abordagem de qualquer condi ção refrativa do olho com astigmatismo regular é mais complicada do que a da miopi...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

Morning glory disc anomaly associated with large facial infantile hemangioma as the presenting signs of PHACE syndrome
ABSTRACT Infantile hemangioma, the most common benign tumor in infancy, is usually an isolated condition occurring in many different locations in the body. However, large infantile hemangioma may be associated with other systemic malformations, including central nervous system, cerebrovascular, cardiac, and ophthalmology abnormalities, a condition termed PHACE syndrome. In this paper, we describe a case of PHACE syndrome that was presented with the unique association of a large facial infantile hemangioma and morning glory anomaly.RESUMO O hemangioma infantil é a causa mais comum de tumor benigno na infância e...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

Subfoveal perfluorocarbon liquid removal by peeling of internal limiting membrane, without retinotomy
ABSTRACT Perfluorocarbon liquid has been widely used during vitreoretinal operations. Subretinal retention is a rare intraoperative complication, but even small quantities can damage the macular structure and function, and no standard treatment has been established. We encountered a 43-year-old woman who presented a retained subfoveal bubble after a vitreoretinal operation due to primary rhegmatogenous retinal detachment. Herein, we describe the procedure we used to remove the perfluorocarbon liquid without retinotomy using internal limiting membrane peeling.RESUMO O perfluorocarbono l íquido tem sido amplamente dur...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

Congenital dacryocystocele diagnosed by antenatal ultrasonography with spontaneous resolution
We report a case of a fetus with bilateral dacryocystocele diagnosed by prenatal ultrasound at the beginning of the third trimester of pregnancy with spontaneous postpartum resorption.RESUMO A dacriocistocele é uma anormalidade facial benigna rara do sistema nasolacrimal, que pode ser detectada na rotina pré-natal durante o terceiro trimestre da gravidez. O ultrassom é o método de escolha, mas a ressonância magnética também pode ser usada em casos específicos. Na maioria das vezes, a dacriocistoc ele é um achado temporário, que pode se resolver espont&aci...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research