Filtered By:
Condition: Hypothyroidism

This page shows you your search results in order of date. This is page number 7.

Order by Relevance | Date

Total 192 results found since Jan 2013.

A Treacherous Twist on ECG
The patient is a 61-year-old female with a history of well-controlled hypothyroidism on levothyroxine supplementation and prior suspected cardioembolic stroke on chronic anticoagulation who previously underwent surgical mitral valve repair 1 year previously due to symptoms of severe fatigue with a baseline left ventricular ejection fraction of 55-60% and non-obstructive coronary artery disease. Immediately following surgery, her left ventricular ejection fraction declined to 40%. Postoperatively, she continued to experience fatigue with gradual worsening of her left ventricular ejection fraction to 30%.
Source: The American Journal of Medicine - October 26, 2021 Category: General Medicine Authors: Tyler J. Bonkowski, Christopher M. Madison, Sanjay Dandamudi, David A. McNamara Tags: ECG Image of the Month Source Type: research

Association of total cholesterol and atherosclerotic cardiovascular disease in patients with follicular thyroid cancer: A real-world study from Chinese populations
The association between serum total cholesterol (TC) level and incident atherosclerotic cardiovascular disease (ASCVD) in patients with follicular thyroid cancer postthyroidectomy is unknown. This was a retrospective study and patients (n = 384) were divided into low and high TC groups according to the median TC level. Incidence of composite ASCVD (myocardial infarction, ischemic stroke, and cardiovascular death) was compared between these 2 groups and factors contributing to the association of TC and ASCVD were evaluated. Patients in the high TC group were older and more likely to have diabetes and have higher C...
Source: Medicine - October 1, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Hypothyroidism is associated with clinical outcomes in patients with acute myocardial infarction: subgroup analysis of China PEACE study
ConclusionCompared with euthyroid status, hypothyroid status has an independent predicting value for adverse cardiovascular events in AMI patients. Further investigations are required to illustrate whether treatment of thyroid dysfunction could improve the prognosis of AMI patients.
Source: Endocrine - September 15, 2021 Category: Endocrinology Source Type: research

ERLEADA ® (apalutamide) Oral Presentations Demonstrate Importance of Prostate Specific Antigen (PSA) as Key Efficacy Indicator and Show Strong Patient Adherence Rates
September 11, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data demonstrating robust prostate-specific antigen (PSA) response and strong adherence rates in patients with non-metastatic castration-resistant prostate cancer (nmCRPC) treated with ERLEADA® (apalutamide) in the real-world clinical setting. The strong PSA response was also seen in a separate post-hoc analysis that showed a correlation between rapid and deep PSA response and prolonged survival in both metastatic castration-sensitive prostate cancer (mCSPC) and nmCRPC. The post-hoc analysis also suppor...
Source: Johnson and Johnson - September 12, 2021 Category: Pharmaceuticals Source Type: news

Janssen Demonstrates Commitment to Advancing Science and Innovation in the Treatment of Solid Tumors at ESMO Annual Congress
September 8, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than ten data presentations from its lung cancer, bladder cancer and prostate cancer portfolio and pipeline will be featured during the European Society for Medical Oncology (ESMO) Annual Congress 2021 virtual meeting, September 16–21. Further details about these data and the science Janssen is advancing will be made available throughout ESMO via the Janssen Oncology Virtual Newsroom.“With a diverse oncology portfolio and pipeline spanning bladder cancer, lung cancer and prostate cancer, Janssen...
Source: Johnson and Johnson - September 8, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Striving to Deliver Better Outcomes: Janssen to Showcase Commitment to Advancing Science for Genitourinary Cancers at AUA 2021
August 31, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today multiple company-sponsored presentations in prostate and bladder cancers will be highlighted at the virtual 2021 American Urological Association Annual Meeting (AUA 2021), September 10-13. “Janssen maintains a strong commitment to advancing innovation and new therapeutic options for patients with genitourinary malignancies. As the treatment of genitourinary cancers becomes more complex, we continue to work with urologists and their teams to improve outcomes for patients across the continuum of disease,” sai...
Source: Johnson and Johnson - August 31, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

P-029 Impact of in-hospital delirium on outcomes of acute ischemic stroke
ConclusionsDelirium complicates ~3.5% of AIS admissions, and is associated with increased risk of in-hospital death, longer stay, higher charges and decrease in likelihood of home discharge.Disclosures D. Pujara: None. H. Kamal: None. O. Mir: None. S. Reddy: None. K. Parsha: None. S. Patil: None. B. Gogia: None. P. Rai: None. C. Sitton: None. M. Chen: None. M. Abraham: None. M. Hussain: None. A. Hassan: None. A. Sarraj: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Pujara, D., Kamal, H., Mir, O., Reddy, S., Parsha, K., Patil, S., Gogia, B., Rai, P., Sitton, C., Chen, M., Abraham, M., Hussain, M., Hassan, A., Sarraj, A. Tags: Oral poster abstracts Source Type: research

Subclinical Thyroid Function and Cardiovascular Events in patients with Atrial Fibrillation
CONCLUSIONS: Subclinical hypothyroidism was not associated with increased CV risk in AF patients. Higher levels of fT4 with normal TSH were associated with higher risk for HF.PMID:34228632 | DOI:10.1530/EJE-20-1442
Source: European Journal of Endocrinology - July 6, 2021 Category: Endocrinology Authors: Elisavet Moutzouri Christina Lyko Martin Feller Manuel Raphael Blum Luise Adam Steffen Blum Stefanie Aeschbacher Urs Fischer Laurent Roten Cinzia Del Giovane Christine S Meyer-Zuern Giulio Conte Leo H Bonati Giorgio Moschovitis Michael Kuehne Juerg Beer D Source Type: research

Thyroid Hormone Therapy and Incident Stroke
CONCLUSIONS: Both exogenous hyper- and hypothyroidism were associated with increased risk of stroke, highlighting the importance of patient medication safety.PMID:34137866 | DOI:10.1210/clinem/dgab444
Source: The Journal of Clinical Endocrinology and Metabolism - June 17, 2021 Category: Endocrinology Authors: Maria Papaleontiou Deborah A Levine David Reyes-Gastelum Sarah T Hawley Mousumi Banerjee Megan R Haymart Source Type: research

Hypothyroidism is associated with clinical outcomes in patients with acute myocardial infarction: subgroup analysis of China PEACE study
ConclusionCompared with euthyroid status, hypothyroid status has an independent predicting value for adverse cardiovascular events in AMI patients. Further investigations are required to illustrate whether treatment of thyroid dysfunction could improve the prognosis of AMI patients.
Source: Endocrine - June 3, 2021 Category: Endocrinology Source Type: research

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health
There is currently limited understanding of the genetic aetiology of obstructive sleep apnoea (OSA). We aimed to identify genetic loci associated with OSA risk, and to test if OSA and its comorbidities share a common genetic background. We conducted the first large-scale genome-wide association study of OSA using the FinnGen study (217 955 individuals) with 16 761 OSA patients identified using nationwide health registries. We estimated 0.08 (95% CI 0.06–0.11) heritability and identified five loci associated with OSA (p<5.0x10–8): rs4837016 near GAPVD1 (GTPase activating protein and VPS9 domains 1), rs1092856...
Source: European Respiratory Journal - May 6, 2021 Category: Respiratory Medicine Authors: Strausz, S., Ruotsalainen, S., Ollila, H. M., Karjalainen, J., Kiiskinen, T., Reeve, M., Kurki, M., Mars, N., Havulinna, A. S., Luonsi, E., Mansour Aly, D., Ahlqvist, E., Teder-Laving, M., Palta, P., Groop, L., Mägi, R., Mäkitie, A., Salom Tags: Sleep medicine Original Articles: Sleep medicine Source Type: research

Targeted Cancer Therapies.
Abstract Targeted cancer therapies involve chemotherapeutic agents that attack, directly or indirectly, a specific genetic biomarker found in a given cancer. Targeted oncology includes monoclonal antibodies, small molecule inhibitors, antibody-drug conjugates, and immunotherapy. For example, the monoclonal antibodies trastuzumab and pertuzumab target human epidermal growth factor receptor 2 (HER2) and are used when treating HER2-positive breast cancer. Although targeted oncology has improved survival by years for some incurable cancers such as metastatic breast and lung cancer, as few as 8% of patients with advanc...
Source: American Family Physician - January 30, 2021 Category: Primary Care Authors: Smith CEP, Prasad V Tags: Am Fam Physician Source Type: research

Subclinical Thyroid Dysfunction and the Risk of Cardiovascular Disease.
Abstract The prevalence of subclinical hypothyroidism (SH) is 3-10%. The prevalence of subclinical hyperthyroidism (SHr) is 0.7-9.7%. Thyroid hormones affect cardiac electrophysiology, contractility, and vasculature.SH is associated with an increased risk of coronary heart disease (CHD), especially in subjects under 65. SHr seems to be associated with a slightly increased risk of CHD and an increase in CHD-related mortality. Both SH and SHr carry an increased risk of developing heart failure (HF), especially in those under 65. Both SH and SHr are associated with worse prognoses in patients with existing HF. SH is ...
Source: Current Pharmaceutical Design - November 17, 2020 Category: Drugs & Pharmacology Authors: Stojković M, Žarković M Tags: Curr Pharm Des Source Type: research

A unique finding of the basilar artery
AbstractVariants of the posterior intracranial circulation are important for surgeon, interventionalists and radiologists. Herein, a unique configuration of the basilar artery is reported. A 54-year-old man with a history of COPD, hypothyroidism, smoking, and hyperlipidemia presented to an outside institution with nausea, confusion, altered mental status, and ataxia. The patient was evaluated for stroke. Imaging revealed rotation of the basilar apex of 180 degrees, fetal configuration of the posterior communicating artery, right posterior cerebral artery filling from the left vertebral artery, and duplication of the left a...
Source: Surgical and Radiologic Anatomy - November 1, 2020 Category: Anatomy Source Type: research