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Condition: Ischemic Stroke

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Before juvenile stroke can be attributed to MYH11 variants, alternative etiologies and pathophysiologies must be adequately ruled out
We read with interest the article by Raghuram et  al. on a 12 year-old female who developed severe ischemic stroke (NIHSS 16) due to right proximal middle cerebral artery (MCA) occlusion [1]. Despite thrombolysis and thrombectomy, the patient's recovery was incomplete [1]. The cause of the occlusion was attributed to a focal dissection of the MCA due to the variant IVS32G>A in MYH11, which was also found in the maternal grandmother, mother, older sister, and a maternal cousin, two of whom had aortic dissection in the past [1].
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2023 Category: Neurology Authors: Josef Finsterer Tags: Letter to the Editor Source Type: research

The effects of low-intensity resistance training with blood flow restriction versus traditional resistance exercise on lower extremity muscle strength and motor functionin ischemic stroke survivors: a randomized controlled trial
CONCLUSION: LIRT-BFR produced a significant improvement in muscle strength, balance, walking capacity, and anxiety and depression in ischemic stroke patients, and the improvement are comparable to HIRT.CLINICAL TRIAL REGISTRATION: NCT05281679.PMID:37724785 | DOI:10.1080/10749357.2023.2259170
Source: Topics in Stroke Rehabilitation - September 19, 2023 Category: Neurology Authors: Ishtiaq Ahmed Rustem Mustafoglu Belgin Erhan Source Type: research

Regional differences in the utilization and outcomes of cerebral embolic protection during transcatheter aortic valve replacement: an analysis of the National Inpatient Sample from 2017 through 2019
Conclusion: Within the USA, there are regional differences in the utilization and outcomes of CEP use during TAVR. To prevent regional disparities and ensure consistent quality of care in the USA, further research is needed to determine what variable(s) may be responsible for regional differences in TAVR outcomes, with or without CEP.PMID:37724712 | DOI:10.57264/cer-2023-0010
Source: Journal of Comparative Effectiveness Research - September 19, 2023 Category: General Medicine Authors: Elisa M Amoroso Source Type: research

Intracranial arterial stenosis and recurrence in stroke patients with different risk stratifications by Essen stroke risk score
CONCLUSION: ICAS was an independent predictor of both 3- and 12-month stroke recurrence in low-risk but not high-risk patients with minor ischemic stroke or transient ischemic attack according to ESRS stratification.PMID:37724803 | DOI:10.1080/01616412.2023.2257415
Source: Neurological Research - September 19, 2023 Category: Neurology Authors: Yue Suo Jing Jing Xia Meng Zixiao Li Yuesong Pan Hongyi Yan Yong Jiang Liping Liu Xingquan Zhao Yilong Wang Hao Li Yongjun Wang CHANCE investigators Source Type: research

The effects of low-intensity resistance training with blood flow restriction versus traditional resistance exercise on lower extremity muscle strength and motor functionin ischemic stroke survivors: a randomized controlled trial
CONCLUSION: LIRT-BFR produced a significant improvement in muscle strength, balance, walking capacity, and anxiety and depression in ischemic stroke patients, and the improvement are comparable to HIRT.CLINICAL TRIAL REGISTRATION: NCT05281679.PMID:37724785 | DOI:10.1080/10749357.2023.2259170
Source: Topics in Stroke Rehabilitation - September 19, 2023 Category: Neurology Authors: Ishtiaq Ahmed Rustem Mustafoglu Belgin Erhan Source Type: research

Pure Sensory Lacunar Infarction in the Thalamus Presented as Bilateral Hypogeusia: A Case Report
CONCLUSION: The exact gustatory pathway in humans remains uncertain nowadays. First, there were few reports about dysgeusia, which might be related to clinical neglect of taste deficits. Second, our knowledge of the human gustatory pathway depends solely on sporadic cases of taste-involved brain lesions. We reported a case of bilateral hypogeusia after right thalamic infarction. This finding indicates that, although there might be laterality of gustatory fibers to the left hemisphere, anatomical variations may exist in the human gustatory system. More research is needed to elucidate the understanding of the gustatory pathw...
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Yu-Chun Wang I-Hsu Chen Poyin Huang Source Type: research

First-Ever Ischemic Stroke In Covid-19: How Is It Different? - A Stroke Registry-Based Study From South India
Acta Neurol Taiwan. 2023 Dec 30;32(4):190-201.ABSTRACTStroke associated with COVID-19 has been characterised in several multicentre retrospective studies and meta-analyses. However, they did not distinguish first-ever ischemic strokes (F-AIS). Therefore, we aimed to study the incidence, clinical characteristics, and outcomes of a cohort of F-AIS associated with COVID-19 during the first wave of the pandemic and compare this cohort with those of F-AIS without COVID-19, COVID-19 without stroke. We also sought to compare the stroke admissions and mechanisms during the pandemic and immediate prepandemic periods.PMID:37723911
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Muralidhar Reddy Y Jagarlapudi Mk Murthy Sreekanth Reddy Y Abhinay Kumar Gattu Shyam K Jaiswal Lalitha Pidaparthi Subhendu Parida Santhosh Kumar B Syed Osman Shanti Naidu Kamatam Source Type: research

Pure Sensory Lacunar Infarction in the Thalamus Presented as Bilateral Hypogeusia: A Case Report
CONCLUSION: The exact gustatory pathway in humans remains uncertain nowadays. First, there were few reports about dysgeusia, which might be related to clinical neglect of taste deficits. Second, our knowledge of the human gustatory pathway depends solely on sporadic cases of taste-involved brain lesions. We reported a case of bilateral hypogeusia after right thalamic infarction. This finding indicates that, although there might be laterality of gustatory fibers to the left hemisphere, anatomical variations may exist in the human gustatory system. More research is needed to elucidate the understanding of the gustatory pathw...
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Yu-Chun Wang I-Hsu Chen Poyin Huang Source Type: research

First-Ever Ischemic Stroke In Covid-19: How Is It Different? - A Stroke Registry-Based Study From South India
Acta Neurol Taiwan. 2023 Dec 30;32(4):190-201.ABSTRACTStroke associated with COVID-19 has been characterised in several multicentre retrospective studies and meta-analyses. However, they did not distinguish first-ever ischemic strokes (F-AIS). Therefore, we aimed to study the incidence, clinical characteristics, and outcomes of a cohort of F-AIS associated with COVID-19 during the first wave of the pandemic and compare this cohort with those of F-AIS without COVID-19, COVID-19 without stroke. We also sought to compare the stroke admissions and mechanisms during the pandemic and immediate prepandemic periods.PMID:37723911
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Muralidhar Reddy Y Jagarlapudi Mk Murthy Sreekanth Reddy Y Abhinay Kumar Gattu Shyam K Jaiswal Lalitha Pidaparthi Subhendu Parida Santhosh Kumar B Syed Osman Shanti Naidu Kamatam Source Type: research

Regional differences in the utilization and outcomes of cerebral embolic protection during transcatheter aortic valve replacement: an analysis of the National Inpatient Sample from 2017 through 2019
Conclusion: Within the USA, there are regional differences in the utilization and outcomes of CEP use during TAVR. To prevent regional disparities and ensure consistent quality of care in the USA, further research is needed to determine what variable(s) may be responsible for regional differences in TAVR outcomes, with or without CEP.PMID:37724712 | DOI:10.57264/cer-2023-0010
Source: Journal of Comparative Effectiveness Research - September 19, 2023 Category: General Medicine Authors: Elisa M Amoroso Source Type: research

Pure Sensory Lacunar Infarction in the Thalamus Presented as Bilateral Hypogeusia: A Case Report
CONCLUSION: The exact gustatory pathway in humans remains uncertain nowadays. First, there were few reports about dysgeusia, which might be related to clinical neglect of taste deficits. Second, our knowledge of the human gustatory pathway depends solely on sporadic cases of taste-involved brain lesions. We reported a case of bilateral hypogeusia after right thalamic infarction. This finding indicates that, although there might be laterality of gustatory fibers to the left hemisphere, anatomical variations may exist in the human gustatory system. More research is needed to elucidate the understanding of the gustatory pathw...
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Yu-Chun Wang I-Hsu Chen Poyin Huang Source Type: research

First-Ever Ischemic Stroke In Covid-19: How Is It Different? - A Stroke Registry-Based Study From South India
Acta Neurol Taiwan. 2023 Dec 30;32(4):190-201.ABSTRACTStroke associated with COVID-19 has been characterised in several multicentre retrospective studies and meta-analyses. However, they did not distinguish first-ever ischemic strokes (F-AIS). Therefore, we aimed to study the incidence, clinical characteristics, and outcomes of a cohort of F-AIS associated with COVID-19 during the first wave of the pandemic and compare this cohort with those of F-AIS without COVID-19, COVID-19 without stroke. We also sought to compare the stroke admissions and mechanisms during the pandemic and immediate prepandemic periods.PMID:37723911
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Muralidhar Reddy Y Jagarlapudi Mk Murthy Sreekanth Reddy Y Abhinay Kumar Gattu Shyam K Jaiswal Lalitha Pidaparthi Subhendu Parida Santhosh Kumar B Syed Osman Shanti Naidu Kamatam Source Type: research

Angiography-based hemodynamic features predict recurrent ischemic events after angioplasty and stenting of intracranial vertebrobasilar atherosclerotic stenosis
ConclusionsIn patients with intracranial vertebrobasilar atherosclerosis treated with PTAS, preprocedural prolonged TTP of the target vessel and shortened trans-stenotic TTP difference were associated with stroke relapse. Q-DSA-defined hemodynamic parameters provided incremental predictive value over conventional parameters for stroke recurrence.Clinical relevance statementQuantitative DSA analysis enables intuitive observation and semi-quantitative evaluation of peri-therapeutic cerebral blood flow. More importantly, quantitative DSA –defined hemodynamic parameters have the potential for risk stratification of patients ...
Source: European Radiology - September 19, 2023 Category: Radiology Source Type: research

Cost of treatment failure: Medicare spending on stroke for atrial fibrillation patients not receiving anticoagulation
It is well known that atrial fibrillation (AF) patients not receiving anticoagulants are at higher risk of Ischemic Stroke (IS).
Source: Journal of the Neurological Sciences - September 19, 2023 Category: Neurology Authors: Steven D. Culler, W. Frank Peacock, April W. Simon Source Type: research