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Condition: Ischemic Stroke

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Total 66853 results found since Jan 2013.

Regarding "Automated Segmentation of Intracranial Thrombus on NCCT and CTA in Patients with Acute Ischemic Stroke Using a Coarse-to-Fine Deep Learning Model" letter
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Tortora, M., Pacchiano, F. Tags: letter Source Type: research

CT Perfusion Does Not Modify the Effect of Reperfusion in Patients with Acute Ischemic Stroke Undergoing Endovascular Treatment in the ESCAPE-NA1 Trial INTERVENTIONAL
CONCLUSIONS: CTP did not modify the effect of near-complete reperfusion on clinical outcomes. Thus, CTP cannot explain why some patients with near-complete reperfusion have poor clinical outcomes.
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Rex, N. B., McDonough, R. V., Ospel, J. M., Kashani, N., Sehgal, A., Fladt, J. C., McTaggart, R. A., Nogueira, R., Menon, B., Demchuk, A. M., Tymianski, M., Hill, M. D., Goyal, M., on behalf of the ESCAPE-NA1 Investigators Tags: INTERVENTIONAL Source Type: research

Neurophysiologic Features Reflecting Brain Injury During Pediatric ECMO Support
ConclusionsIncreased seizure burden and increased interhemispheric differences in both quantitative electroencephalographic amplitude and TCD MCA TIBI scores are independently associated with acute brain injury in children undergoing ECMO support.
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research

Noninvasive Characterization of Metabolic Changes in Ischemic Stroke Using Z-spectrum-fitted Multiparametric Chemical Exchange Saturation Transfer-weighted Magnetic Resonance Imaging
ConclusionThe Z-spectrum-fitted multiparametric CEST-MRI can comprehensively detect metabolic alterations in ischemic brain tissues.
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - September 11, 2023 Category: Research Source Type: research

Case Report: Giant Cell Arteritis-Related Stroke
Thromboembolic events are major contributors to the morbidity and mortality of patients with giant cell arteritis (GCA), but little is known about how GCA may increase the risk of ischemic strokes. GCA-related stroke is described as an ischemic cerebral infarct occurring within three to four weeks of GCA diagnosis and treatment. It occurs in 3–7%... [Read More]
Source: The Rheumatologist - September 10, 2023 Category: Rheumatology Authors: Jessica Meek, MD, Anna Coppinger, DO, & Sejal Khan, DO Tags: Conditions Home Slider Vasculitis case report GCA giant cell arteritis (GCA) stroke Source Type: research

Floor-to-Stand Performance Among People Following Stroke
CONCLUSIONS: The TSS demonstrates concurrent validity with physical performance measures.IMPACT: Findings serve to improve functional mobility examination after stroke and to formulate effective treatment interventions to improved floor-to-stand performance.PMID:37690073 | DOI:10.1093/ptj/pzad122
Source: Physical Therapy - September 10, 2023 Category: Physiotherapy Authors: Angela F Davis Dennis W Klima Amanda Leonard Stephanie A Miller Source Type: research

MCPIP-1 knockdown enhances endothelial colony-forming cell angiogenesis via the TFRC/AKT/mTOR signaling pathway in the ischemic penumbra of MCAO mice
In this study, we performed Proteome Profiler™ Human Angiogenesis Antibody arrays and tandem mass tag protein profiling to investigate the effect of MCPIP-1 on ECFCs. We demonstrated that MCPIP-1 knockdown enhanced the proliferation, migration, and in vivo and in vitro angiogenic capacity of ECFCs by upregulating the transferrin receptor-activated AKT/m-TOR signaling pathway to promote cellular trophic factor secretion. Furthermore, we found that the lateral ventricular transplantation of ECFCs with lentiviral MCPIP-1 knockdown into mice with middle cerebral artery occlusion increased serum vacular endothelial growth fac...
Source: Experimental Neurology - September 9, 2023 Category: Neurology Authors: Xiaoxiong Zou Yu Xie Zhongfei Zhang Zhiming Feng Jianbang Han Qian Ouyang Shiting Hua Sixian Huang Cong Li Zhizheng Liu Yingqian Cai Yuxi Zou Yanping Tang Haijia Chen Xiaodan Jiang Source Type: research

Environmental enrichment enhanced neurogenesis and behavioral recovery after stroke in aged rats
CONCLUSIONS: EE improved post-stroke recovery on the basis of enhancing neurogenesis in aged rats.PMID:37688770 | DOI:10.18632/aging.205010
Source: Aging - September 9, 2023 Category: Biomedical Science Authors: Ji Yan Yan Liu Fangda Zheng Dan Lv Di Jin Source Type: research

Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes
Int J Mol Sci. 2023 Aug 30;24(17):13452. doi: 10.3390/ijms241713452.ABSTRACTWe aimed to analyse whether patients with ischaemic stroke (IS) occurring within eight days after the onset of COVID-19 (IS-COV) are associated with a specific aetiology of IS. We used SUPERGNOVA to identify genome regions that correlate between the IS-COV cohort (73 IS-COV cases vs. 701 population controls) and different aetiological subtypes. Polygenic risk scores (PRSs) for each subtype were generated and tested in the IS-COV cohort using PRSice-2 and PLINK to find genetic associations. Both analyses used the IS-COV cohort and GWAS from MEGASTRO...
Source: Atherosclerosis - September 9, 2023 Category: Cardiology Authors: Laia Lluci à-Carol Elena Mui ño Natalia Cullell Jara C árcel-Márquez Miquel Lled ós Cristina Gallego-Fabrega Jes ús Martin-Campos Joan Mart í-Fàbregas Ana Aguilera-Sim ón Anna M Planas Marta L DeDiego Alicia de Felipe Mimbrera Jaime Masjuan Sebas Source Type: research

Identification of Novel Circular RNA Targets in Key Penumbra Region of Rats After Cerebral Ischemia-Reperfusion Injury
AbstractCircular RNAs (circRNAs) are abundantly and stably expressed in the brain of mammals and humans. Some circRNAs are implicated in ischemic stroke. Therefore, we aimed to detect how circRNAs change in the key penumbra area during cerebral ischemia-reperfusion (CI/R) injury. Rats were subjected to transient middle cerebral artery occlusion (tMCAO), during which the permanent blocking period was 2 h and reperfusion time was 24 or 72 h. Then modified neurologic severity score (mNSS), triphenyl tetrazolium chloride (TTC) staining and HE staining were used to exhibiting damage between rats in different groups. The penumbr...
Source: Journal of Molecular Neuroscience - September 9, 2023 Category: Neuroscience Source Type: research

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