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Specialty: Cardiology
Condition: Obesity
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Total 639 results found since Jan 2013.
Psychosocial and behavioral characteristics of still smokers at 6 months after acute cerebro or cardiovascular events: Findings from INEV@L, a prospective pilot study
ConclusionOur pilot study in young workers highlights the low rate of smoking cessation, and generalized dual use of electronic + conventional cigarette at mid-term after acute MI or stroke. Our findings further suggest specific PSF pattern of non-quitters, associated with loss of perceived disease severity.
Source: Archives of Cardiovascular Diseases Supplements - January 7, 2020 Category: Cardiology Source Type: research
Effects of Blood Pressure Lowering Agents on Cardiovascular Outcomes in Weight Excess Patients: A Systematic Review and Meta-analysis
ConclusionsIn hypertensive subjects with excess weight, diuretics are more effective for preventing HF and stroke than CCB and ACEI, respectively. CCB are a good first-line choice for prevention of cardiovascular disease, except HF.
Source: American Journal of Cardiovascular Drugs - January 2, 2020 Category: Cardiology Source Type: research
HFpEF Is the Substrate for Stroke in Obesity and Diabetes Independent of Atrial Fibrillation
Publication date: January 2020Source: JACC: Heart Failure, Volume 8, Issue 1Author(s): Milton PackerAbstractBoth obesity and type 2 diabetes are important risk factors for the development of heart failure with a preserved ejection fraction (HFpEF), and both disorders increase the risk of systemic thromboembolic events. Traditionally, the risk of stroke has been explained by the strong association of these disorders with atrial fibrillation (AF). However, adiposity and diabetes are risk factors for systemic thromboembolism, even in the absence of AF, because both can lead to the development of an inflammatory and fibrotic a...
Source: JACC: Heart Failure - December 31, 2019 Category: Cardiology Source Type: research
CXCL2, a new critical factor and therapeutic target for cardiovascular diseases.
Abstract
Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Previous studies have shown that inflammatory chemokines are involved in the physiological functions of cytoskeletal reorganization, cell migration, adhesion and immune responses. However, in the past decade, there have been studies showing that inflammatory chemokines play a key role in CVD. Importantly, CXC motif chemokine ligand 2 (CXCL2) has been shown to be involved in the pathogenesis of cardiovascular disease. CXCL2 exerts its effects on the cardiovascular system by mediating inflammatory responses, but the specific signaling ...
Source: Clinical and Experimental Hypertension - November 20, 2019 Category: Cardiology Authors: Guo LY, Yang F, Peng LJ, Li YB, Wang AP Tags: Clin Exp Hypertens Source Type: research
Self-monitoring of blood pressure in patients with hypertension related multi-morbidity: Systematic review and individual patient data meta-analysis.
CONCLUSIONS: Self-monitoring lowers BP regardless of the number of hypertension-related co-morbidities, but may only be effective in conditions such obesity or stroke when combined with high intensity co-interventions.
PMID: 31730171 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 14, 2019 Category: Cardiology Authors: Sheppard JP, Tucker KL, Davison WJ, Stevens R, Aekplakorn W, Bosworth HB, Bove A, Earle K, Godwin M, Green BB, Hebert P, Heneghan C, Hill N, Hobbs FDR, Kantola I, Kerry SM, Leiva A, Magid DJ, Mant J, Margolis KL, McKinstry B, McLaughlin MA, McNamara K, Om Tags: Am J Hypertens Source Type: research
HFpEF Is the Substrate for Stroke in Obesity and Diabetes Independent of Atrial Fibrillation
Publication date: Available online 6 November 2019Source: JACC: Heart FailureAuthor(s): Milton PackerAbstractBoth obesity and type 2 diabetes are important risk factors for the development of heart failure with a preserved ejection fraction (HFpEF), and both disorders increase the risk of systemic thromboembolic events. Traditionally, the risk of stroke has been explained by the strong association of these disorders with atrial fibrillation (AF). However, adiposity and diabetes are risk factors for systemic thromboembolism, even in the absence of AF, because both can lead to the development of an inflammatory and fibrotic ...
Source: JACC: Heart Failure - November 8, 2019 Category: Cardiology Source Type: research
Association of obesity with cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease: Insights from TECOS
ConclusionsThe majority of TECOS participants with ASCVD and T2D were overweight or obese, yet overweight or obese class I individuals had lower CV risk than those who were under/normal weight. These results suggest the presence of an obesity paradox, but this paradox may reflect an epidemiological artifact rather than a true negative association between normal weight and clinical outcomes.
Source: American Heart Journal - October 21, 2019 Category: Cardiology Source Type: research
Analysis of comorbidities in hospitalized patients for ischemic stroke and their effects on lethality.
CONCLUSION: This study demonstrates that medico-administrative databases and factorial statistical methods are perfectly adapted to confirm the ischemic stroke risk factors. This type of study will allow to target with more precision the secondary and tertiary prevention actions of stroke.
PMID: 31542203 [PubMed - as supplied by publisher]
Source: Annales de Cardiologie et d'Angeiologie - September 17, 2019 Category: Cardiology Authors: Savsin M, Dubourg D, Coppieters Y, Collart P Tags: Ann Cardiol Angeiol (Paris) Source Type: research
Risk Factor Management for Atrial Fibrillation.
Authors: Joung B
Abstract
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in the general population. Many cardiovascular diseases and concomitant conditions increase the risk of the development of AF, recurrent AF, and AF-associated complications. Knowledge of these factors and their management is hence important for the optimal management of patients with AF. Recent studies have suggested that lowering the blood pressure threshold can improve the patients' outcome. Moreover, adverse events associated with a longer duration of hypertension can be prevented through strict blood pressure cont...
Source: Korean Circulation Journal - August 30, 2019 Category: Cardiology Tags: Korean Circ J Source Type: research
Allograft inflammatory factor-1, a multi-target regulator of atherosclerosis
Atherosclerosis is a chronic inflammatory disease of the arterial wall responsible for ischemic heart disease and stroke, the most frequent causes of death worldwide. Cardiovascular diseases are expected to remain the main cause of death globally within the next 15 years, owing to a rapidly increasing prevalence, mainly due to the rising incidence of obesity and diabetes on a global scale in both developed and developing economies. This forces us to consider new strategies for prediction, prevention, and treatment of cardiovascular disease [1].
Source: Atherosclerosis - August 22, 2019 Category: Cardiology Authors: Yujiao Zhang, Alain Tedgui, Hafid Ait-Oufella Source Type: research
Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association.
ular Biology; Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Council on Clinical Cardiology
Abstract
Hypertriglyceridemia (triglycerides 200-499 mg/dL) is relatively common in the United States, whereas more severe triglyceride elevations (very high triglycerides, ≥500 mg/dL) are far less frequently observed. Both are becoming increasingly prevalent in the United States and elsewhere, likely driven in large part by growing rates of obesity and diabetes mellitus. In a 2002 American Heart Association scientific stat...
Source: Circulation - August 18, 2019 Category: Cardiology Authors: Skulas-Ray AC, Wilson PWF, Harris WS, Brinton EA, Kris-Etherton PM, Richter CK, Jacobson TA, Engler MB, Miller M, Robinson JG, Blum CB, Rodriguez-Leyva D, de Ferranti SD, Welty FK, American Heart Association Council on Arteriosclerosis, Thrombosis and Vas Tags: Circulation Source Type: research
High high-sensitivity C-reactive protein/BMI ratio predicts future adverse outcomes in patients with acute coronary syndrome
Objective
The prognostic value of high-sensitivity C-reactive protein (hsCRP) and obesity in patients with coronary artery disease is controversial. In previous studies, hsCRP was significantly associated with BMI. Thus, we integrated hsCRP and BMI to assess the predictive value in patients with acute coronary syndrome (ACS).
Methods and results
In this observational cohort study, 478 patients with ACS were enrolled in Fuwai Hospital from 2010 to 2011,with a mean follow-up of 4.2 years. The endpoint of major adverse cardiovascular events (MACE) was the composite of cardiovascular death, myocardial infarction, revascul...
Source: Coronary Artery Disease - August 6, 2019 Category: Cardiology Tags: Risk Stratification Source Type: research
Self-Reported Daytime Sleepiness and Sleep-Disordered Breathing in Patients with Atrial Fibrillation: SNOozE-AF
ConclusionsIn an ambulatory AF population, SDB was common but most patients reported low daytime sleepiness levels. Clinical features, rather than daytime sleepiness, were predictive of patients with moderate-to-severe SDB. Lack of excessive daytime sleepiness should not preclude patients from being investigated for the potential presence of concomitant SDB
Source: Canadian Journal of Cardiology - August 2, 2019 Category: Cardiology Source Type: research
Achievement of target SBP without attention to decrease in DBP can increase cardiovascular morbidity in treated arterial hypertension: the Campania Salute Network
Objectives:
Results of the SPRINT study have influenced recent guidelines on arterial hypertension, in the identification of target SBP, but scarce attention has been paid to the consequences on DBP. However, there is evidence that reducing DBP too much can be harmful.
Methods:
We analyzed outcome in 4005 treated hypertensive patients (22% obesity, 8% diabetes and 21% current smoking habit) with target attended office SBP less than 140 mmHg, in relation to quintiles of DBP, cardiovascular risk profile and target organ damage (LV hypertrophy, carotid plaque and left atrial dilatation). Composite fatal and nonfatal ca...
Source: Journal of Hypertension - August 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research
Obesity Paradox in TAVR: Nationwide Study from 2011-14 Comparing Outcomes of Patients with versus without Obesity Undergoing TAVR
Obesity is associated with several cardiovascular diseases including aortic valve stenosis. Studies have demonstrated a beneficial effect of obesity on patients with cardiovascular disease, deemed the “obesity paradox.” This paradox is also present in obese patients undergoing total aortic valve replacement (TAVR) when examining both short and long-term mortality rates, although the data is conflicting. We aim to investigate the effects of obesity on mortality, length of hospital stay, and ra tes of stroke and cardiogenic shock in patients undergoing TAVR.
Source: Journal of Cardiac Failure - July 31, 2019 Category: Cardiology Authors: Hassaan B. Arshad, Aneil Bhalla, Sara Ayaz Butt, Rehan Umar, Umar Jamshed Sharif Khwaja, Hashim Jilani Tags: 385 Source Type: research
