Filtered By:
Condition: Obesity

This page shows you your search results in order of date. This is page number 17.

Order by Relevance | Date

Total 4516 results found since Jan 2013.

ApoC-III Proteoforms, Plasma Lipids, and Cardiovascular Risk in MESA
CONCLUSIONS: Our data indicate differences in clinical and demographic relationships of apoC-III proteoforms, and highlight the importance of apoC-III proteoform composition in predicting future lipid patterns and cardiovascular disease risk.PMID:37317850 | DOI:10.1161/ATVBAHA.123.319035
Source: Arteriosclerosis, Thrombosis and Vascular Biology - June 15, 2023 Category: Cardiology Authors: Shripad Sinari Juraj Koska Yueming Hu Jeremy Furtado Majken K Jensen Matthew J Budoff Dobrin Nedelkov Robyn L McClelland Dean Billheimer Peter Reaven Source Type: research

Association of polycystic ovary syndrome with cardiovascular disease among US female hospitalizations
CONCLUSIONS: PCOS is associated with CVD events and the association is mediated by obesity and metabolic syndrome conditions, particularly among hospitalized women less than or equal to age 40 years in the US.PMID:37307574 | DOI:10.1093/ejendo/lvad067
Source: European Journal of Endocrinology - June 12, 2023 Category: Endocrinology Authors: Alok Kumar Dwivedi Deepanjali Vishwakarma Pallavi Dubey Sireesha Reddy Source Type: research

Melatonin modulates the aggravation of pyroptosis, necroptosis, and neuroinflammation following cerebral ischemia and reperfusion injury in obese rats
This study aimed to investigate the roles of melatonin on pyroptosis, necroptosis, and pro-inflammatory pathways occurring in the I/R brain of obese rats. Male Wistar rats were given a high-fat diet for 16 weeks to induce the obese condition, and then were divided into 4 groups: Sham-operated, I/R treated with vehicle, I/R treated with melatonin (10 mg/kg), and I/R treated with glycyrrhizic acid (10 mg/kg). All drugs were administered via intraperitoneal injection at the onset of reperfusion. The development of neurological deficits, cerebral infarction, histological changes, neuronal death, and glial cell hyperactivation ...
Source: Biochimica et Biophysica Acta - June 11, 2023 Category: Biochemistry Authors: Nuttapong Yawoot Jirakhamon Sengking Piyarat Govitrapong Chainarong Tocharus Jiraporn Tocharus Source Type: research

Astragaloside IV alleviates neuronal ferroptosis in ischemic stroke by regulating fat mass and obesity ‐associated—N6‐methyladenosine—acyl‐CoA synthetase long‐chain family member 4 axis
Ischemic stroke (IS) is a detrimental neurological disease with limited treatments options. Astragaloside IV (As-IV) was a promising bioactive constituent in the treatment of IS. In our study, As-IV promoted the transcription of fat mass and obesity-associated (Fto) by upregulating activating transcription factor 3(Atf3), resulting in a decrease of long-chain acyl-CoA synthetase-4 (Acsl4) N6-methyladenosine (m6A) levels, thus improving neuronal injury in IS by inhibiting ferroptosis. These findings provided a better understanding of the molecular mechanisms underlying the neuroprotective effects of As-IV and led to novel t...
Source: Journal of Neurochemistry - June 10, 2023 Category: Neuroscience Authors: Zhenglong Jin, Wenying Gao, Fu Guo, Shaojun Liao, Mingzhe Hu, Tao Yu, Shangzhen Yu, Qing Shi Tags: ORIGINAL ARTICLE Source Type: research

DOACs use in extreme body-weighted patients: results from the prospective START-register
ConclusionsDOACs seem to be effective and safe also for the treatment of patients with extreme body weights, both underweight and overweight. Further prospective studies are needed to support these findings.
Source: Internal and Emergency Medicine - June 10, 2023 Category: Emergency Medicine Source Type: research

Long-term cardiometabolic effects of ambient ozone pollution in a large Chinese population
Ecotoxicol Environ Saf. 2023 Jun 7;261:115115. doi: 10.1016/j.ecoenv.2023.115115. Online ahead of print.ABSTRACTLimited studies investigated the effects of long-term ozone exposure on cardiometabolic health. We aimed to examine the association of long-term ozone exposure with a range of cardiometabolic diseases, as well as the subclinical indicators in Eastern China. The study included 202,042 adults living in 11 prefecture-level areas in Zhejiang Province between 2014 and 2021. Using a satellite-based model with a 1 × 1 km spatial resolution, we estimated residential 5-year average ozone exposures for each subject. Mixed...
Source: Ecotoxicology and Environmental Safety - June 9, 2023 Category: Environmental Health Authors: Li Yang Yixiang Zhu Bowen Zhao Wenjing Wan Su Shi Cheng Xuan Caiyan Yu Wei Mao Jing Yan Source Type: research

Is early age at menarche associated with multimorbidity? Findings from the Azar Cohort study
CONCLUSION: Changes in AAM have significant health implications. Factors predisposing individuals to early menarche and its consequences should be considered in chronic disease prevention strategies for adolescents and young adults.PMID:37290234 | DOI:10.1016/j.ejogrb.2023.05.029
Source: Reproductive Biology - June 8, 2023 Category: Reproduction Medicine Authors: Amin SadrAzar Sarvin Sanaie Helda Tutunchi Bahare Sheikh Elnaz Faramarzi Neda Jourabchi-Ghadim Source Type: research

Endocan is Related to Increased Cardiovascular Risk in Type 2 Diabetes Mellitus Patients
Conclusion: Endocan was the independent predictor for moderate and high estimated risks (i.e., nonfatal and fatal CHD and nonfatal stroke risk scores) in T2D patients. When included in models with sex and obesity indices endocan demonstrated good clinical accuracy in discriminating T2D patients with high risk for nonfatal and fatal eCHD and nonfatal stroke risk from those patients with low risk.PMID:37279462 | DOI:10.1089/met.2023.0050
Source: Atherosclerosis - June 6, 2023 Category: Cardiology Authors: Aleksandra Klisic Jelena Kotur-Stevuljevic Ana Ninic Source Type: research

Clinical effectiveness and safety of edoxaban in obese patients — Results of the prospective Dresden NOAC Registry (NCT01588119)
Edoxaban is a direct factor Xa inhibitors approved for stroke prevention in atrial fibrillation (SPAF) and for venous thromboembolism (VTE) treatment. Edoxaban is given in a fixed dosing regimen (with recommended dose reductions for patients with renal impairment or body weight  
Source: Thrombosis Research - June 2, 2023 Category: Hematology Authors: Luise Tittl, Christina K öhler, Sandra Marten, Christiane Naue, Kristina Fache, Laura Stanneck, Thomas Schreier, Jan Beyer-Westendorf Tags: Letter to the Editors-in-Chief Source Type: research

Epidemiology of Stroke in a General Japanese Population: The Hisayama Study
J Atheroscler Thromb. 2023 May 30. doi: 10.5551/jat.RV22004. Online ahead of print.ABSTRACTThe Hisayama Study is an ongoing epidemiological study of stroke, coronary artery disease (CAD), and other noncommunicable diseases in a general Japanese population established in 1961. According to the longitudinal data from the Hisayama Study, average levels of systolic blood pressure among hypertensive individuals have decreased with time since 1961. In contrast, the prevalence of metabolic risk factors such as obesity, hypercholesterolemia, and glucose intolerance has increased with time. The incidence rates of ischemic stroke in...
Source: Journal of Atherosclerosis and Thrombosis - May 31, 2023 Category: Cardiology Authors: Jun Hata Toshiharu Ninomiya Source Type: research