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Condition: Metabolic Syndrome

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Total 926 results found since Jan 2013.

Obstructive Sleep Apnea and Stroke: Determining the Mechanisms Behind their Association and Treatment Options
AbstractSleep-disordered breathing (SDB) can be a sequela of stroke caused by vascular injury to vital respiratory centers, cerebral edema, and increased intracranial pressure of space-occupying lesions. Likewise, obstructive sleep apnea (OSA) contributes to increased stroke risk through local mechanisms such as impaired ischemic cerebrovascular response and systemic effects such as promoting atherosclerosis, hypercoagulability, cardiac arrhythmias, vascular-endothelial dysfunction, and metabolic syndrome. The impact of OSA on stroke outcomes has been established, yet it receives less attention in national guidelines on st...
Source: Translational Stroke Research - March 16, 2023 Category: Neurology Source Type: research

Cardiovascular Risks in Testicular Cancer: Assessment, Prevention, and Treatment
AbstractPurpose of ReviewTesticular cancer (TC) is the leading cancer in men between 18 and 39  years of age. Current treatment involves tumor resection followed by surveillance and/or one or more lines of cisplatin-based chemotherapy (CBCT) and/or bone marrow transplant (BMT). Ten years after treatment, CBCT has been associated with significant atherosclerotic cardiovascular disease (CVD) i ncluding myocardial infarction (MI), stroke, and heightened rates of hypertension, dyslipidemia, diabetes mellitus, and metabolic syndrome (MetS). Additionally, low testosterone levels and hypogonadism contribute to MetS and may furth...
Source: Current Oncology Reports - March 3, 2023 Category: Cancer & Oncology Source Type: research

A Potential Strategy for Atherosclerosis Prevention in Modernizing China - Hyperhomocysteinemia, MTHFR C677T Polymorphism and Air Pollution (PM2.5) on Atherogenesis in Chinese Adults
CONCLUSION: HC and PM2.5 pollution but not MTHFR genotype were both related to carotid IMT, independent of other traditional risk factors. This has potential implications in dietary and AP strategies for atherosclerosis prevention in China.PMID:36806868 | DOI:10.1007/s12603-023-1889-x
Source: Atherosclerosis - February 22, 2023 Category: Cardiology Authors: C Y T Kwok Y K P Poon P Chook D S Guo C Q Lin Y H Yin D S Celermajer K S Woo Source Type: research

Association between baseline cardiovascular risk and incidence rates of major adverse cardiovascular events and malignancies in patients with psoriatic arthritis and psoriasis receiving tofacitinib
CONCLUSION: In tofacitinib-treated patients with PsA/PsO, increased ASCVD risk and baseline MetS were associated with higher IRs for MACE and malignancies. Our results support assessing CV risk in patients with PsA/PsO and suggest enhanced cancer monitoring in those with increased ASCVD risk.REGISTRATION CLINICALTRIALSGOV: NCT01877668/NCT01882439/NCT01976364/NCT00678210/NCT01710046/NCT01241591/NCT01186744/NCT01276639/NCT01309737/NCT01163253.PLAIN LANGUAGE SUMMARY: People who have psoriatic arthritis or psoriasis may have more heart-related problems and cancer if they have a higher risk of cardiovascular disease: A study in...
Source: Adv Data - February 13, 2023 Category: Epidemiology Authors: Lars E Kristensen Bruce Strober Denis Poddubnyy Ying-Ying Leung Hyejin Jo Kenneth Kwok Ivana Vranic Dona L Fleishaker Lara Fallon Arne Yndestad Dafna D Gladman Source Type: research

Exploring the role of lipoprotein(a) in cardiovascular diseases and diabetes in Chinese population
Int J Biol Macromol. 2023 Feb 7:123586. doi: 10.1016/j.ijbiomac.2023.123586. Online ahead of print.ABSTRACTA high level of lipoprotein (a) in the plasma has been associated with a variety of cardiovascular diseases and is considered to be an independent predictor of some other diseases. Based on recent studies, the concentration levels of Lp(a) in the Chinese population exhibit a distinctive variation from other populations. In the Chinese population, a high level of Lp(a) indicates a higher incidence of revascularization, platelet aggregation, and thrombogenicity following PCI. Increased risk of atherosclerotic cardiovasc...
Source: International Journal of Biological Macromolecules - February 9, 2023 Category: Biochemistry Authors: Zubair Hussain Hongcai Liu Junaid Iqbal Hou-De Zhou Source Type: research

A Potential Strategy for Atherosclerosis Prevention in Modernizing China — Hyperhomocysteinemia, MTHFR C677T Polymorphism and Air Pollution (PM2.5) on Atherogenesis in Chinese Adults
ConclusionHC and PM2.5 pollution but not MTHFR genotype were both related to carotid IMT, independent of other traditional risk factors. This has potential implications in dietary and AP strategies for atherosclerosis prevention in China.
Source: The Journal of Nutrition, Health and Aging - February 3, 2023 Category: Nutrition Source Type: research

Association of hyperuricemia with cardiovascular diseases: current evidence
Hosp Pract (1995). 2023 Feb 2. doi: 10.1080/21548331.2023.2173413. Online ahead of print.ABSTRACTThe aim of the present study is to present a historical and unified perspective on the association of serum uric acid (SUA) in the cause cardiovascular diseases (CVDs). The association of hyperuricemia (HUC) with CVD begun to be appreciated in the middle 1950s and early 1990s when clinical evidence was shown on the association of HUC with CVD. However, this association was disputed by several investigators including the Framingham group and by professional societies, like the American Heart Association and the American Society ...
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Steven G Chrysant Source Type: research

Urinary 20-HETE: A prospective Non-Invasive prognostic and diagnostic marker for diabetic kidney disease
CONCLUSION: Taken together, our results suggest that urinary 20-HETE levels can potentially be used as non-invasive diagnostic and prognostic markers for DKD.PMID:36725183 | DOI:10.1016/j.jare.2022.04.013
Source: Adv Data - February 1, 2023 Category: Epidemiology Authors: Pamela Houeiss Rachel Njeim Hani Tamim Ahmed F Hamdy Tanya S Azar William S Azar Mohamed Noureldein Youssef H Zeidan Awad Rashid Sami T Azar Assaad A Eid Source Type: research

From self-care behaviours to cardiometabolic risks prevention for the health of farmers: Nursing implications
CONCLUSION: The farmers in this study had a high prevalence of cardiometabolic risks, a high probability of stroke, inadequate number of remaining teeth and poor oral hygiene behaviours. These findings can provide evidence to develop health promotion programmes for farmers.IMPACT: This study demonstrates the health needs of farmers. We strongly recommend that community nurses empower farmers to engage in self-care behaviours through tailored health promotion programmes. For instance, by discussing cardiometabolic risk prevention from the farmers' perspectives to improve their health literacy.PMID:36695405 | DOI:10.1111/jan.15571
Source: Adv Data - January 25, 2023 Category: Epidemiology Authors: Yu-Ting Huang Ming-Shyan Lin Kathy James Chia-Hao Chang Wen-Hsuen Tsai Yu-Chih Lin Mei-Yen Chen Source Type: research

Cardiovascular events and risk in patients with systemic lupus erythematosus: Systematic literature review and meta-analysis
CONCLUSIONS: This meta-analysis found an increased risk of stroke, MI, CVD, and hypertension in patients with SLE compared with the general population, despite substantial heterogeneity across the included studies.PMID:36547368 | DOI:10.1177/09612033221147471
Source: Lupus - December 22, 2022 Category: Rheumatology Authors: Natalia Bello Kristin J Meyers Jennifer Workman Louise Hartley Maureen McMahon Source Type: research

Independent risk factors for an increased incidence of thromboembolism after lung transplantation
ConclusionsThe incidence of TE after LTX is high, especially in lung transplant recipients with a BMI  >  25 and an age >  55 years as well as cardiovascular risk factors closely associated with the metabolic syndrome. As these patients comprise a growing recipient fraction, intensified research should focus on the risks and benefits of regular screening or a prolonged TE prophylaxis in these patients.Trial registration number DKRS: 00021501.
Source: Journal of Thrombosis and Thrombolysis - December 10, 2022 Category: Hematology Source Type: research

Interrelationships between body mass index, total IgE, and blood eosinophils count in healthy subjects
Conclusion: This study showed an independent relationship between B-Eos count and total IgE in healthy subjects. When adjusted for total IgE, the association between B-Eos count and BMI disappeared whereas the association with current smoking remained, indicating possible different mechanisms underlying increased B-Eos count upon these exposures.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Amaral, R., Jacinto, T., Malinovschi, A., Janson, C., Price, D., Fonseca, J., Alving, K. Tags: 05.03 - Allergy and immunology Source Type: research

Chronic non-communicable diseases: Hainan prospective cohort study
Purpose The Hainan Cohort was established to investigate the incidence, morbidity and mortality of non-communicable diseases and their risk factors in the community population. Participants The baseline investigation of the Hainan Cohort study was initiated in five main areas of Hainan, China, from June 2018 to October 2020. A multistage cluster random-sampling method was used to obtain samples from the general population. Baseline assessments included a questionnaire survey, physical examination, blood and urine sample collection, and laboratory measurements, and outdoor environmental data were obtained. Findings to dat...
Source: BMJ Open - November 18, 2022 Category: General Medicine Authors: Gu, X., Lin, L., Zhao, C., Wu, L., Liu, Y., He, L., Lin, G., Lin, Y., Zhang, F. Tags: Open access, Public health Source Type: research