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Condition: Metabolic Syndrome
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Total 926 results found since Jan 2013.
Hyperviscosity syndrome in COVID-19 and related vaccines: exploring of uncertainties
In conclusion, COVID-19 and related vaccines are linked with the development of HVS, mainly in patients with previous COVID-19 and underlying metabolic derangements. The possible mechanism of HVS in COVID-19 and related vaccines is increasing levels of fibrinogen and immunoglobulins. However, dehy dration, oxidative stress, and inflammatory reactions are regarded as additional contributing factors in the pathogenesis of HVS in COVID-19. However, this critical review cannot determine the final causal relationship between COVID-19 and related vaccines and the development of HVS. Prospective and retrospective studies are warranted in this field.
Source: Clinical and Experimental Medicine - May 24, 2022 Category: Research Source Type: research
TG/HDL-C ratio as a predictor of stroke in the population with healthy BMI: The Jichi Medical School Cohort Study
This study examined whether TG/HDL-C helps in predicting stroke onset; this was compared between the whole population and healthy body mass index (BMI) population.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - May 15, 2022 Category: Nutrition Authors: Fumitaka Sato, Yosikazu Nakamura, Kazunori Kayaba, Shizukiyo Ishikawa Source Type: research
Meal Timing, Meal Frequency and Metabolic Syndrome
Nutrients. 2022 Apr 21;14(9):1719. doi: 10.3390/nu14091719.ABSTRACTIndividuals with metabolic syndrome have increased risk for developing health conditions, including cardiovascular diseases and stroke. Modifiable risk factors, such as exercise and diet, are key components in the prevention and control of metabolic syndrome. Specifically, dietary patterns and habits are extremely successful in controlling more than one of the metabolic syndrome risk factors. Meal timing and frequency have been associated with type 2 diabetes, cardiovascular diseases, and other chronic conditions. However, there is limited evidence linking ...
Source: Cancer Control - May 14, 2022 Category: Cancer & Oncology Authors: Fatema Alkhulaifi Charles Darkoh Source Type: research
Pyruvate Kinase M2: a novel regulator of adipogenesis
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.L7944.ABSTRACTObesity is the cornerstone of many other conditions, with far-reaching impacts on numerous body systems and quality of life. Obesity is closely and likely causally associated with metabolic syndrome and consequent atherosclerosis, heart disease, stroke, and type 2 diabetes as well as diseases such as cancer and osteoarthritis. Recent studies suggest exploring the possibility of activating brown adipose tissue as a potential anti-obesity strategy. However, understanding the mechanisms underlying the processes of brown adipogenesis and browning is fou...
Source: Atherosclerosis - May 13, 2022 Category: Cardiology Authors: Presley D Dowker Jenna B Demeter Ahmed Bettaieb Source Type: research
Mitochondrial health quality control: measurements and interpretation in the framework of predictive, preventive, and personalized medicine
AbstractMitochondria are the “gatekeeper” in a wide range of cellular functions, signaling events, cell homeostasis, proliferation, and apoptosis. Consequently, mitochondrial injury is linked to systemic effects compromising multi-organ functionality. Although mitochondrial stress is common for many pathomechanisms, individ ual outcomes differ significantly comprising a spectrum of associated pathologies and their severity grade. Consequently, a highly ambitious task in the paradigm shift from reactive to predictive, preventive, and personalized medicine (PPPM/3PM) is to distinguish between individual disease predispos...
Source: EPMA Journal - May 12, 2022 Category: International Medicine & Public Health Source Type: research
Acute glycemic variability and mortality of patients with acute stroke: a meta-analysis
Increased glucose fluctuation has been related to poor prognosis in patients with critical illnesses, while its prognostic role in patients with acute stroke remains unknown. The meta-analysis aimed to evaluat...
Source: Diabetology and Metabolic Syndrome - May 10, 2022 Category: Endocrinology Authors: Jinbo Lin, Chunsheng Cai, Yituan Xie and Li Yi Tags: Research Source Type: research
Heart health in polycystic ovary syndrome: time to act on the data
Fertil Steril. 2022 May;117(5):885-886. doi: 10.1016/j.fertnstert.2022.03.014.ABSTRACTPolycystic ovary syndrome (PCOS), first described over 80 years ago, is a chronic condition with gynecologic, metabolic, and psychologic manifestations. Both hyperandrogenism and insulin resistance are associated with the high prevalence of cardiometabolic risk factors described in this population. Although robust data in reproductive-age women demonstrate a high rate of obesity, impaired glucose tolerance, hypertension, dyslipidemia, and metabolic syndrome, studies show mixed results in the adolescent and menopausal age groups. There is ...
Source: Atherosclerosis - May 5, 2022 Category: Cardiology Authors: Anuja Dokras Source Type: research
Bidirectional relationships of comorbidity with obstructive sleep apnoea
Obstructive sleep apnoea (OSA) is frequently associated with comorbidities that include metabolic, cardiovascular, renal, pulmonary and neuropsychiatric. There is considerable evidence that OSA is an independent risk factor for many of these comorbidities but, more recently, there is evidence that some of these comorbidities may predispose to the development of OSA. Thus, there is growing evidence of a bidirectional relationship between OSA and comorbidity, especially for heart failure, metabolic syndrome and stroke. Potential mechanisms of bidirectional relationships differ in individual comorbidities with fluid retention...
Source: European Respiratory Review - May 4, 2022 Category: Respiratory Medicine Authors: Gleeson, M., McNicholas, W. T. Tags: Sleep medicine Reviews Source Type: research
Differential prognostic value of resistin for cardiac death in patients with coronary artery disease according to the presence of metabolic syndrome
AbstractResistin is associated with atherosclerosis progression by affecting inflammation and insulin resistance. There are controversial data regarding the prognostic value of resistin in stable coronary artery disease (CAD) patients. We prospectively investigated the long-term prognostic value of resistin in patients with stable CAD. A total 741 consecutive patients with stable CAD were followed for a median of 5.5 years. Serum resistin, lipids, high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6) levels were measured at baseline. Primary endpoints were cardiac death and secondary hospitalizations for a...
Source: Heart and Vessels - April 20, 2022 Category: Cardiology Source Type: research
Visceral Adiposity and Risk of Stroke: A Mendelian Randomization Study
ConclusionsThis study provides potential evidence for a causal role of VAT in ischemic stroke and could suggest novel genetical therapeutic strategies for distinct subtypes of ischemic stroke.
Source: Frontiers in Neurology - April 11, 2022 Category: Neurology Source Type: research
Differential prognostic value of resistin for cardiac death in patients with coronary artery disease according to the presence of metabolic syndrome
AbstractResistin is associated with atherosclerosis progression by affecting inflammation and insulin resistance. There are controversial data regarding the prognostic value of resistin in stable coronary artery disease (CAD) patients. We prospectively investigated the long-term prognostic value of resistin in patients with stable CAD. A total 741 consecutive patients with stable CAD were followed for a median of 5.5 years. Serum resistin, lipids, high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6) levels were measured at baseline. Primary endpoints were cardiac death and secondary hospitalizations for a...
Source: Heart and Vessels - April 7, 2022 Category: Cardiology Source Type: research
Impact of Sarcopenia on Functional Outcomes Among Patients With Mild Acute Ischemic Stroke and Transient Ischemic Attack: A Retrospective Study
CONCLUSIONS: In this study, the prevalence of sarcopenia in patients with stroke was lower than most of previous studies and patients with sarcopenia showed higher likelihood for unfavorable functional outcomes at 90 days after acute ischemic stroke or TIA. Further investigation of the interventions for treating sarcopenia and its impact on the outcome of ischemic stroke patients is needed.PMID:35370897 | PMC:PMC8964497 | DOI:10.3389/fneur.2022.841945
Source: Atherosclerosis - April 4, 2022 Category: Cardiology Authors: Hyungwoo Lee Il Hyung Lee JoonNyung Heo Minyoul Baik Hyungjong Park Hye Sun Lee Hyo Suk Nam Young Dae Kim Source Type: research
High triglyceride is an independent predictor of high on-treatment platelet reactivity in ischemic stroke patients
In this study, we attempted to evaluate the association between TG and high on-treatment platelet reactivity (HTPR) in IS patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2022 Category: Neurology Authors: Haoxuan Chen, Yibo Zhan, Zhenzhen Lou, Hui Mao, Changlin Zhang, Xiaojun Li, Guixian Chen, Huiying Ouyang, Zhiping Huang, Longlong Wen, Haoyou Xu, Zequan Zheng, Yuanqi Zhao, Min Zhao Source Type: research
