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Specialty: Cardiology
Condition: Heart Valve Disease

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Total 185 results found since Jan 2013.

Comparative Surgical Outcomes of Prosthetic and Native Valve Endocarditis
CONCLUSIONS: PVE carried significant perioperative risks, and was an independent risk factor of overall mortality.PMID:34085423 | PMC:PMC8176072 | DOI:10.4070/kcj.2020.0448
Source: Korean Circulation Journal - June 4, 2021 Category: Cardiology Authors: Won Kyung Pyo Ho Jin Kim Joon Bum Kim Sung Ho Jung Suk Jung Choo Cheol Hyun Chung Jae Won Lee Source Type: research

Clinical consequences of consecutive self-expanding transcatheter heart valve iterations
CONCLUSIONS: TAVI with self-expanding valves was safe, and device iterations may result in a lower need for PPI. More-than-mild PVL seemed to occur less often with repositionable technology.PMID:33914259 | DOI:10.1007/s12471-021-01568-5
Source: Netherlands Heart Journal - April 29, 2021 Category: Cardiology Authors: H G Kroon L van Gils F Ziviello M P H van Wiechen J F W Ooms Z Rahhab N El Faquir A-M Maugenest J A Goudzwaard P Cummins M Lenzen I Kardys J Daemen F Mattace-Raso P P T de Jaegere N M Van Mieghem Source Type: research

Comparison of Direct Oral Anticoagulants versus Warfarin in Patients with Atrial Fibrillation and Bioprosthetic Heart Valves
The objectives of this study were to evaluate the ambulatory utilization of DOACs and to compare the effectiveness and safety of DOACs versus warfarin in patients with AF and BHVs. We conducted a retrospective cohort study at a large integrated health care delivery system in California. Patients with BHVs and AF treated with warfarin, dabigatran, rivaroxaban or apixaban between September 12, 2011 and June 18, 2020 were identified.
Source: The American Journal of Cardiology - January 30, 2021 Category: Cardiology Authors: Lewei Duan, Jason N Doctor, John L Adams, John A Romley, Leigh-Anh Nguyen, Jaejin An, Ming-Sum Lee Source Type: research

Rivaroxaban Versus Warfarin in Patients with Mechanical Heart Valves: Open-Label, Proof-of-Concept trial —The RIWA study
ConclusionsIn this pilot study, rivaroxaban 15  mg twice daily had thromboembolic and bleeding events similar to warfarin in patients with mechanical heart valves. These data confirm the authors’ proof-of-concept and suggest that a larger trial with a similar design is not unreasonable.ClinicalTrial.gov identifierNCT03566303.
Source: American Journal of Cardiovascular Drugs - November 5, 2020 Category: Cardiology Source Type: research

Contemporary Diagnosis and Management of Rheumatic Heart Disease: Implications for Closing the Gap: A Scientific Statement From the American Heart Association.
Stroke Nursing; and Council on Clinical Cardiology Abstract The global burden of rheumatic heart disease continues to be significant although it is largely limited to poor and marginalized populations. In most endemic regions, affected patients present with heart failure. This statement will seek to examine the current state-of-the-art recommendations and to identify gaps in diagnosis and treatment globally that can inform strategies for reducing disease burden. Echocardiography screening based on World Heart Federation echocardiographic criteria holds promise to identify patients earlier, when prophylaxis is more...
Source: Circulation - October 19, 2020 Category: Cardiology Authors: Kumar RK, Antunes MJ, Beaton A, Mirabel M, Nkomo VT, Okello E, Regmi PR, Reményi B, Sliwa-Hähnle K, Zühlke LJ, Sable C, American Heart Association Council on Lifelong Congenital Heart Disease and Heart Health in the Young; Council on Cardiovascular and Tags: Circulation Source Type: research

Novel oral anticoagulant vs. warfarin in elderly atrial fibrillation patients with normal, mid ‐range, and reduced left ventricular ejection fraction
ConclusionsIn elderly AF patients ≥65 years, using NOAC was associated with lower IS/SE compared with warfarin in normal and mid‐range LVEF but not in reduced LVEF. Using NOACs was associated with lower death compared with warfarin in normal LVEF.
Source: ESC Heart Failure - July 15, 2020 Category: Cardiology Authors: Victor Chien ‐Chia Wu, Chun‐Li Wang, Cheng‐Hung Lee, Yu‐Ling Chen, Hui‐Tzu Tu, Michael Wu, Chang‐Fu Kuo, Shao‐Wei Chen, Yu‐Tung Huang, Ming‐Shien Wen, Shang‐Hung Chang Tags: Original Research Article Source Type: research

Impact of Valvular Heart Disease on Mortality, Thromboembolic and Cardiac Events in Japanese Patients With Atrial Fibrillation  - The Fushimi AF Registry.
CONCLUSIONS: Although VHD did not significantly affect thromboembolism or mortality, it affected cardiac events depending on type, with aortic valve diseases having higher risk, in Japanese patients with AF. PMID: 32213725 [PubMed - as supplied by publisher]
Source: Circulation Journal - March 24, 2020 Category: Cardiology Authors: Doi K, Ogawa H, Ishigami K, Ikeda S, Aono Y, Hamatani Y, Fujino A, An Y, Ishii M, Iguchi M, Masunaga N, Esato M, Tsuji H, Wada H, Hasegawa K, Abe M, Akao M, Fushimi AF Registry Investigators Tags: Circ J Source Type: research

Is oral anticoagulation effective in preventing transcatheter aortic valve implantation failure? A propensity matched analysis of the Italian Transcatheter balloon-Expandable valve Registry study
Conclusion After TAVI with Edwards Sapien valve OAT did not reduce the incidence of valve dysfunction and stroke but was responsible for mortality and bleeding increases.
Source: Journal of Cardiovascular Medicine - December 27, 2019 Category: Cardiology Tags: Research articles: Interventional cardiology Source Type: research

Impact of Severity of Chronic Kidney Disease on Management and Outcomes Following Transcatheter Aortic Valve Replacement With Newer-Generation Transcatheter Valves.
CONCLUSIONS: In this prospective study of adults undergoing TAVR with newer-generation THVs, moderate and severe CKD was associated with a nearly 2-fold and 3-fold higher risk of 30-day readmission, respectively. PMID: 31841995 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - December 18, 2019 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Can Direct Oral Anticoagulants Be Used for Stroke Prevention Among Patients with Valvular Atrial Fibrillation?
AbstractPurpose of ReviewTo review the clinical evidence underlying the efficacy and safety of the use of direct oral anticoagulants (DOACs) for the treatment of patients with valvular atrial fibrillation (AF).Recent FindingsThe recent focused update to the 2014 AHA/ACC/HRS Atrial Fibrillation Guidelines defines valvular AF as AF in the setting of moderate-to-severe mitral stenosis (MS) and/or in the presence of a mechanical heart valve. Landmark clinical trials of DOACs in patients with AF systematically excluded these patient populations. However, there are trial data in both animals and humans regarding the use of DOACs...
Source: Current Cardiology Reports - August 30, 2019 Category: Cardiology Source Type: research