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Specialty: Cardiology
Condition: Heart Valve Disease

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Total 185 results found since Jan 2013.

Invasive Hemodynamic Characteristics of Low Gradient Severe Aortic Stenosis Despite Preserved Ejection Fraction
Conclusions: Occurrence of low gradient severe aortic stenosis despite preserved ejection fraction was confirmed by invasive hemodynamics and was not the result of a systematic bias in the echo calculation of aortic orifice area.
Source: Journal of the American College of Cardiology - April 24, 2013 Category: Cardiology Authors: Juliane Lauten, Christian Rost, Ole A. Breithardt, Christian Seligmann, Lutz Klinghammer, Werner G. Daniel, Frank A. Flachskampf Tags: Heart Valve Disease Source Type: research

Triple Antithrombotic Therapy With Prasugrel in the Stented Patient: Concern for More Bleeding⁎
There is a large body of evidence, including results of prospective trials, that supports oral anticoagulation therapy (OAT) as the optimal strategy to prevent fibrin-centric thrombotic events (FCTEs). Examples of FCTEs include thromboembolism in patients with mechanical heart valves, deep vein thrombosis, and atrial fibrillation (AF) (). In a large prospective trial, warfarin was found to be superior to dual antiplatelet therapy (DAPT) with aspirin + clopidogrel in the prevention of vascular events in patients with AF plus 1 or more risk factors for stroke (). European and American guidelines include a Class I recommendat...
Source: Journal of the American College of Cardiology - March 25, 2013 Category: Cardiology Authors: Paul A. Gurbel, Udaya S. Tantry Tags: Interventional Cardiology: Editorial Comment Source Type: research

Transcatheter Aortic Valve Implantation With the Edwards SAPIEN Versus the Medtronic CoreValve Revalving System Devices A Multicenter Collaborative Study: The PRAGMATIC Plus Initiative (Pooled-RotterdAm-Milano-Toulouse In Collaboration)
ObjectivesThe aim of this study was to compare outcomes after transfemoral transcatheter aortic valve implantation with the Medtronic CoreValve (MCV) versus the Edwards SAPIEN/SAPIEN XT transcatheter heart valve (ESV) for severe aortic stenosis.BackgroundNo large matched comparison study has been conducted so far evaluating both commercially available devices.MethodsThe data from databases of 4 experienced European centers were pooled and analyzed. Due to differences in baseline clinical characteristics, propensity score matching was performed. Study objectives were Valve Academic Research Consortium outcomes at 30 days an...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - February 18, 2013 Category: Cardiology Source Type: research

Transcatheter Aortic Valve Replacement: Current Developments, Ongoing Issues, Future Outlook
Since the first clinical implantation in 2002, transcatheter aortic valve implantation or transcatheter aortic valve replacement (TAVR) has become an established therapy in the treatment of symptomatic severe aortic stenosis in patients deemed too high risk for surgical aortic valve replacement. With over 50,000 implants performed in more than 40 countries, a large amount of clinical data have emerged in this rapidly growing field. Careful patient selection, systematic risk stratification, optimal valve sizing, meticulous procedural techniques, and complications management are all important elements to achieve good outcome...
Source: Cardiology in Review - February 15, 2013 Category: Cardiology Tags: Review Articles Source Type: research

Transcatheter Aortic Valve Implantation With the Edwards SAPIEN Versus the Medtronic CoreValve Revalving System Devices: A Multicenter Collaborative Study: The PRAGMATIC Plus Initiative (Pooled-RotterdAm-Milano-Toulouse In Collaboration)
Objectives: The aim of this study was to compare outcomes after transfemoral transcatheter aortic valve implantation with the Medtronic CoreValve (MCV) versus the Edwards SAPIEN/SAPIEN XT transcatheter heart valve (ESV) for severe aortic stenosis. Background: No large matched comparison study has been conducted so far evaluating both commercially available devices. Methods: The data from databases of 4 experienced European centers were pooled and analyzed. Due to differences in baseline clinical characteristics, propensity score matching was performed. Study objectives were Valve Academic Research Consortium outcomes ...
Source: Journal of the American College of Cardiology - January 21, 2013 Category: Cardiology Authors: Alaide Chieffo, Gill Louise Buchanan, Nicolas M. Van Mieghem, Didier Tchetche, Nicolas Dumonteil, Azeem Latib, Robert M.A. van der Boon, Olivier Vahdat, Bertrand Marcheix, Bruno Farah, Patrick W. Serruys, Jean Fajadet, Didier Carrié, Peter P.T. de Jaeger Tags: Heart Valve Disease Source Type: research