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Atherosclerosis in systemic lupus erythematosus
Publication date: Available online 16 October 2017 Source:Best Practice & Research Clinical Rheumatology Author(s): Sara Croca, Anisur Rahman Cardiovascular disease (CVD), comprising coronary heart disease and stroke, is one of the most important causes of death in patients with systemic lupus erythematosus (SLE). The risks of developing both clinical CVD and sub-clinical atherosclerosis are increased in patients with SLE. This increase is not fully explained by traditional cardiovascular risk factors such as smoking, hypertension and elevated cholesterol, and it is believed that immune dysfunction also contribute...
Source: Best Practice and Research Clinical Rheumatology - December 5, 2017 Category: Rheumatology Source Type: research

Morphological changes of the internal carotid artery: prevalence and characteristics. A clinical and ultrasonographic study in a series of 19 804 patients over 25 years old
ConclusionMorphological changes of the internal carotid arteries were associated with aging, female gender and patients with hyperlipidemia, hypertension, diabetes and heart disease. Kinking was associated with ipsilateral cerebral ischemia.
Source: European Journal of Neurology - November 17, 2017 Category: Neurology Authors: H. F. G. Martins, A. Mayer, P. Batista, F. Soares, V. Almeida, A. J. Pedro, V. Oliveira Tags: Original Article Source Type: research

Morphological changes of the internal carotid artery: prevalence and characteristics. A clinic and ultrasonographic study in a series of 19,804 patients over 25 years old
ConclusionMcICA are associated to aging, female gender, and patients with hyperlipidemia, hypertension, diabetes and heart disease. Kinking is associated with ipsilateral cerebral ischemia.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - October 20, 2017 Category: Neurology Authors: Hugo F.G. Martins, Alexandra Mayer, Paulo Batista, F átima Soares, Vanessa Almeida, Ana Júlia Pedro, Victor Oliveira Tags: Original Article Source Type: research

'Exercise pill' could potentially help people with heart failure
Conclusion The protein hCT1 caused heart muscles to grow in a more healthy way in rodents with heart failure. When treatment stopped, the heart went back to its original condition – something that does not happen when the heart grows in a dysfunctional way. There is currently no cure for heart failure and treatment is only available for keeping symptoms under control. Therefore, this very promising early-stage research with potential for developing a drug for people with heart failure, has huge implications. However, it is important to remember that as this is experimental laboratory research, there are many more stage...
Source: NHS News Feed - August 9, 2017 Category: Consumer Health News Tags: Heart/lungs Source Type: news

The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence
Conclusions: Population level of iAs% and DMA%, but not MMA%, were associated with arsenic exposure levels. Overall, study findings suggest that higher MMA% was associated with an increased risk of cancer and cardiovascular disease, while lower MMA% was associated with an increased risk of diabetes and metabolic syndrome. Additional population-based studies and experimental studies are needed to further evaluate and understand the role of arsenic exposure in arsenic metabolism and the role of arsenic metabolism in disease development. https://doi.org/10.1289/EHP577 Received: 01 June 2016 Revised: 26 February 2017 Acce...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Individual and Joint Effects of Early-Life Ambient PM2.5 Exposure and Maternal Prepregnancy Obesity on Childhood Overweight or Obesity
Conclusions: In the present study, we observed that early life exposure to PM2.5 may play an important role in the early life origins of COWO and may increase the risk of COWO in children of mothers who were overweight or obese before pregnancy beyond the risk that can be attributed to MPBMI alone. Our findings emphasize the clinical and public health policy relevance of early life PM2.5 exposure. https://doi.org/10.1289/EHP261 Received: 29 March 2016 Revised: 08 August 2016 Accepted: 23 August 2016 Published: 14 June 2017 Address correspondence to X. Wang, Center on the Early Life Origins of Disease, Department of P...
Source: EHP Research - June 14, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Admixture Mapping of Subclinical Atherosclerosis and Subsequent Clinical Events Among African Americans in 2 Large Cohort Studies Original Articles
Conclusions— We identified several novel LEA regions, in addition to previously identified genetic variations, associated with cCIMT and cardiovascular disease events among African Americans.
Source: Circulation: Cardiovascular Genetics - April 13, 2017 Category: Cardiology Authors: Shendre, A., Wiener, H., Irvin, M. R., Zhi, D., Limdi, N. A., Overton, E. T., Wassel, C. L., Divers, J., Rotter, J. I., Post, W. S., Shrestha, S. Tags: Cardiovascular Disease, Epidemiology, Genetic, Association Studies, Ultrasound, Atherosclerosis Original Articles Source Type: research

Peripheral arteries may be reliable indicators of coronary vascular disease
This article is protected by copyright. All rights reserved.
Source: The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology - February 28, 2017 Category: Molecular Biology Authors: Christopher L. Hoehmann, Bennett Futterman, Brian Lee Beatty Tags: Full Length Article Source Type: research

Peripheral arteries may be reliable indicators of coronary vascular disease.
This article is protected by copyright. All rights reserved. PMID: 28244238 [PubMed - as supplied by publisher]
Source: Anatomical Record - February 27, 2017 Category: Anatomy Authors: Hoehmann CL, Futterman B, Beatty BL Tags: Anat Rec (Hoboken) Source Type: research

Comparison of Carotid Plaque Score and Coronary Artery Calcium Score for Predicting Cardiovascular Disease Events: The Multi-Ethnic Study of Atherosclerosis Epidemiology
BackgroundCoronary artery calcium (CAC) predicts coronary heart disease (CHD) events better than carotid wall plaque presence; however, differences in the utility of CAC burden and carotid plaque burden across the spectrum of cardiovascular disease (CVD) events is unknown.Methods and ResultsCVD, CHD and stroke/transient ischemic attack (TIA) events were evaluated prospectively in a multiethnic cohort without CVD at baseline. Carotid plaque score was determined by the number of ultrasound‐detected plaques in the common, bifurcation, and internal carotid artery segments. CAC was detected by computed tomography. Predictive ...
Source: JAHA:Journal of the American Heart Association - February 14, 2017 Category: Cardiology Authors: Gepner, A. D., Young, R., Delaney, J. A., Budoff, M. J., Polak, J. F., Blaha, M. J., Post, W. S., Michos, E. D., Kaufman, J., Stein, J. H. Tags: Epidemiology, Primary Prevention, Risk Factors, Computerized Tomography (CT), Magnetic Resonance Imaging (MRI) Original Research Source Type: research

Utility of Duranta, a wireless patch-type electrocardiographic monitoring system developed in Japan, in detecting covert atrial fibrillation in patients with cryptogenic stroke: A case report
Rationale: Subcutaneous implantable electrocardiographs are highly effective in detecting covert atrial fibrillation (AF) in cryptogenic stroke. However, these invasive devices are not indicated for all cryptogenic stroke patients, and noninvasive improvements over conventional Holter-type ambulatory electrocardiography are needed. We evaluated the clinical application and effectiveness of Duranta (ImageONE Co., Ltd.), a wireless patch-type electrocardiographic monitoring system developed in Japan for chronically ill patients or home-based patients at the end of life. A Duranta device was used to detect covert AF in patien...
Source: Medicine - February 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

The Troms ø Study 1974-2016: forty years of cardiovascular research.
The Tromsø Study 1974-2016: forty years of cardiovascular research. Scand Cardiovasc J. 2016 Sep 21;:1-16 Authors: Njølstad I, Mathiesen EB, Schirmer H, Thelle DS Abstract The rapid increase of coronary heart disease mortality in Northern Norway during 1951-1970 was why the newly established University of Tromsø decided to start a study to identify major operating cardiovascular risk factors. The first Tromsø survey in 1974 suggested that the relatively high cardiovascular mortality was associated with elevated cholesterol levels and high prevalence of smoking, while high-density-lipoprotein-choles...
Source: Scandinavian Cardiovascular Journal - September 23, 2016 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Cardiovascular diseases in patients 65 years and younger with non-cardiogenic stroke.
CONCLUSIONS: Aetiologically heterogeneous stroke and cardiogenic stroke are the most commonly observed among young stroke patients. Cardiomyopathy and atrial fibrillation are the most common sources of cerebral embolism in young patients with cardiogenic stroke. Nearly 1/5 of patients with a non-cardiogenic stroke have congenital or acquired structural changes in the heart. PMID: 27279848 [PubMed]
Source: Archives of Medical Science - June 10, 2016 Category: Journals (General) Tags: Arch Med Sci Source Type: research

Lower limb peripheral arterial disease in 268 patients in Guadeloupe.
CONCLUSION: In our population, an infrapopliteal site was more often found than a proximal site. Distal localization was associated with diabetes, and proximal localization with smoking. Cardiovascular risk factors exhibited an atypical pattern with a large majority of patients (88 %) having high blood pressure, two-thirds diabetes, but with very few (7 %) smokers. Peripheral arterial disease was more often associated with a history of stroke than with ischemic heart disease. PMID: 27289257 [PubMed - as supplied by publisher]
Source: Journal des Maladies Vasculaires - June 7, 2016 Category: Cardiology Authors: Bélaye L, Lurel D, Ezelin F, Cassin F, Lutin J, Porcène JA, Helissey P, Blanchet-Deverly A Tags: J Mal Vasc Source Type: research

Prevalence of Abdominal Aortic Aneurysm in Men Aged 65-74 Years in a Metropolitan Area in North-East Spain.
CONCLUSIONS: The current screening prevalence of AAA among men aged 65-74 years in a metropolitan area in north-east Spain is similar to that in northern Europe. Smoking, myocardial infarction, and height were associated with the presence of AAA. PMID: 27252078 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - May 28, 2016 Category: Surgery Authors: Salvador-González B, Martín-Baranera M, Borque-Ortega Á, Sáez-Sáez RM, de Albert-Delas Vigo M, Carreño-García E, Tarín-Masriera L, Badia-Millán P, Martínez-Gil M, Torrabadella-Fàbrega J Tags: Eur J Vasc Endovasc Surg Source Type: research

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