Pitfalls in the diagnosis of myositis
Publication date: Available online 13 February 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Hector Chinoy, James B. LillekerAbstractThe idiopathic inflammatory myopathies are a group of heterogeneous autoimmune connective tissue diseases. Despite increase in the understanding of these conditions, securing a timely diagnosis and accurate subtype classification remains difficult in some cases. This has important implications for patients, where delayed or inappropriate treatments can have a negative effect on outcomes.Several conditions can mimic myositis, including metabolic myopathies, genetic m...
Source: Best Practice and Research Clinical Rheumatology - February 14, 2020 Category: Rheumatology Source Type: research

Inflammatory muscle disease – An update
Publication date: Available online 8 February 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Sara Baig, Julie J. PaikAbstractIdiopathic inflammatory myopathies (IIM) are a heterogeneous group of inflammatory myopathies whose common feature is immune-mediated muscle injury. There are distinct subgroups including dermatomyositis (DM), polymyositis (PM), inclusion body myositis, and immune-mediated necrotizing myopathy. Antisynthetase syndrome is also emerging as a distinct subgroup with its unique muscle histopathological characteristic of perifascicular necrosis. While the newly updated EULAR/ACR C...
Source: Best Practice and Research Clinical Rheumatology - February 9, 2020 Category: Rheumatology Source Type: research

The microbiome in autoimmune rheumatic disease
Publication date: Available online 7 February 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Maximilian F. KonigAbstractMicrobial contributions to the immunopathogenesis of autoimmune rheumatic diseases have been studied since the advent of germ theory in the 19th century. With the exception of Group A Streptococcus in rheumatic fever, early studies failed to establish causal relationships between specific pathobionts and rheumatic disease. Today, systemic autoimmune diseases are thought to result from a complex interplay of environmental factors, individual genetic risk, and stochastic events. In...
Source: Best Practice and Research Clinical Rheumatology - February 8, 2020 Category: Rheumatology Source Type: research

Evaluation and monitoring of established rheumatoid arthritis
Publication date: Available online 7 February 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Isabel CastrejonAbstractEstablished rheumatoid arthritis (RA) is a term used to distinguish patients with longer disease duration versus early RA or undifferentiated arthritis that may progress to RA. Although, there is no uniform definition for early disease, a cut-off of 2 years is used in most clinical trials and observational studies. In the evaluation of established RA, clinicians should incorporate a comprehensive set of measures addressing: (1) disease activity, especially inflammation that may bene...
Source: Best Practice and Research Clinical Rheumatology - February 8, 2020 Category: Rheumatology Source Type: research

Connective tissue diseases (excluding SLE)
Publication date: Available online 4 February 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ariane L. Herrick, Fredrick M. Wigley (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - February 5, 2020 Category: Rheumatology Source Type: research

The relationships between cancer and autoimmune rheumatic diseases
Publication date: Available online 3 February 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Laura C. Cappelli, Ami A. ShahAbstractLinks between autoimmune rheumatic diseases and cancer continue to be elucidated. In this review, we explore this complex, bidirectional relationship. First, the increased risk of cancer across the breadth of the autoimmune rheumatic diseases is described. The magnitude of risk and types of tumors seen can differ by the type of autoimmune disease, timing of disease course, and even clinical and laboratory features within a particular autoimmune disease, suggesting that...
Source: Best Practice and Research Clinical Rheumatology - February 4, 2020 Category: Rheumatology Source Type: research

Established rheumatoid arthritis – Redefining the concept
Publication date: Available online 29 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Katerina Chatzidionysiou, George E. FragoulisAbstractDuring the last few years, there has been a shift of focus in rheumatoid arthritis (RA) research towards earlier disease states. The terms early and established RA are inseparable, and having a clear definition of these two terms is crucial in conducting research and trying to understand the immunopathological mechanisms behind these different disease states. Established RA has been connected to chronic inflammation and a high burden of long-standing dis...
Source: Best Practice and Research Clinical Rheumatology - January 30, 2020 Category: Rheumatology Source Type: research

Raynaud's phenomenon
Publication date: Available online 29 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ariane L. Herrick, Fredrick M. WigleyAbstractRaynaud's phenomenon (RP) is common, affecting approximately 5% of the population, and is important to the rheumatologist because it is often the presenting symptom of connective tissue disease, especially of systemic sclerosis (SSc)-spectrum disorders. RP therefore provides a window of opportunity for early diagnosis. When RP is associated with SSc it is particularly challenging to treat.This review begins with a discussion of some of the recent advances in our...
Source: Best Practice and Research Clinical Rheumatology - January 30, 2020 Category: Rheumatology Source Type: research

Toward better outcomes in Sjögren's syndrome: The promise of a stratified medicine approach
Publication date: Available online 28 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ghaith Noaiseh, Alan N. BaerAbstractSjögren's syndrome is a systemic autoimmune disease defined by its targeted inflammation of the salivary and lacrimal glands, resulting in dry mouth and eyes in the majority and persistent or recurrent salivary gland enlargement in a minority of those affected. Involvement of major organs, an increased risk of lymphoma, and autoantibodies against ubiquitous cellular ribonucleoproteins define some of its systemic features. Those affected have a high symptom burden an...
Source: Best Practice and Research Clinical Rheumatology - January 29, 2020 Category: Rheumatology Source Type: research

Established rheumatoid arthritis. The pathogenic aspects
Publication date: Available online 27 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Serena Bugatti, Emanuele Bozzalla Cassione, Ludovico De Stefano, Antonio ManzoAbstractThe development of rheumatoid arthritis (RA), at least in its autoantibody-positive subset, evolves through a series of events starting well before the appearance of synovitis. The distinction between ‘early’ and ‘established’ RA is, therefore, an evolving concept. In routine practice, however, the management of RA still starts with the occurrence of clinically detectable synovitis. As such, the sy...
Source: Best Practice and Research Clinical Rheumatology - January 28, 2020 Category: Rheumatology Source Type: research

Assessment of structural damage progression in established rheumatoid arthritis by conventional radiography, computed tomography, and magnetic resonance imaging
Publication date: Available online 27 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Lykke Midtbøll Ørnbjerg, Mikkel ØstergaardAbstractStructural damage progression in patients with established rheumatoid arthritis (RA) has traditionally been assessed by conventional radiography (CR), which has proven its value in clinical practice and clinical trials over the past decades. The most prominent abnormalities visualized by CR in RA patients are erosions as a consequence of bone destruction and joint space narrowing (JSN) as a consequence of cartilage damage. Several valid...
Source: Best Practice and Research Clinical Rheumatology - January 28, 2020 Category: Rheumatology Source Type: research

When the first visit to the rheumatologist is established rheumatoid arthritis
Publication date: Available online 27 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Peter C. Taylor, Shing T. LawAbstractThe outlook for people living with rheumatoid arthritis (RA) has improved tremendously in a generation. Major contributions to this include recognition of the importance of early treatment initiation, improved understanding of the pathobiology, the identification of therapeutic targets and their subsequent validation in clinic trials and the realisation of the importance of ‘tight control’ of inflammatory responses. Despite these advances, many patients meet...
Source: Best Practice and Research Clinical Rheumatology - January 28, 2020 Category: Rheumatology Source Type: research

Established Rheumatoid Arthritis
Publication date: Available online 28 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ana M. Ortiz, Sebnem Ataman (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - January 28, 2020 Category: Rheumatology Source Type: research

Nonpharmacological treatment in established rheumatoid arthritis
Publication date: Available online 25 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ayşe A. KüçükdeveciAbstractThe goals in the management of established rheumatoid arthritis (RA) are to control pain and disease activity, prevent further joint damage, and enhance functioning and quality of life. Despite the fact that aggressive and the early use of biological and nonbiological disease-modifying antirheumatic drugs have been associated with substantial gains in clinical, radiological, and disability outcomes, a considerable proportion of patients still report significant ...
Source: Best Practice and Research Clinical Rheumatology - January 25, 2020 Category: Rheumatology Source Type: research

The epidemiology of established rheumatoid arthritis
Publication date: Available online 25 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Teresa Otón, Loreto CarmonaAbstractNo published epidemiological study has specifically focused on the prevalence of established rheumatoid arthritis (RA), as epidemiologists do not study established RA separated from RA as a whole; especially no incidence studies can be found, as incidence refers to new cases (early RA). Such a study, if it existed, would find a prevalence much larger than that of recent-onset RA, and should be planned based on clear definitions that currently do not exist in epidem...
Source: Best Practice and Research Clinical Rheumatology - January 25, 2020 Category: Rheumatology Source Type: research

Autoantibodies in connective tissue disease
Publication date: Available online 14 December 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ben Mulhearn, Sarah L. Tansley, Neil J. McHughAbstractAutoimmune connective tissue diseases are heterogeneous rheumatic diseases with the potential to affect multiple body systems. Autoantibodies are a characteristic feature of these diseases and are typically highly disease specific. In addition to aiding diagnosis, many autoantibodies have established associations with clinically important disease complications including internal organ involvement. In this chapter, we review the autoantibodies relevant ...
Source: Best Practice and Research Clinical Rheumatology - January 21, 2020 Category: Rheumatology Source Type: research

Systemic sclerosis: Advances towards stratified medicine
Publication date: Available online 21 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): A. Quinlivan, L. Ross, S. ProudmanAbstractEpidemiological studies reporting demographic, clinical and serological factors predictive of various outcomes in systemic sclerosis (SSc) range from the prediction of mortality to the development and progression of disease manifestations. However, predicting the disease trajectory in the individual patient is a challenging but important step towards a stratified approach to disease management. Recent technological advances provide the opportunity for new subgroupi...
Source: Best Practice and Research Clinical Rheumatology - January 21, 2020 Category: Rheumatology Source Type: research

Antiphospholipid syndrome
Publication date: Available online 19 December 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Lisa R. SammaritanoAbstractAntiphospholipid syndrome is an autoimmune systemic disorder characterized by arterial, venous, or small vessel thrombosis and/or recurrent early pregnancy loss, fetal loss, or pregnancy morbidity in the setting of documented persistent antiphospholipid antibodies that include the lupus anticoagulant, or moderate-high titer anticardiolipin, or anti-β2Glycoprotein I antibodies. Associated clinical manifestations include livedo reticularis, cutaneous ulcerations, thrombocytop...
Source: Best Practice and Research Clinical Rheumatology - December 20, 2019 Category: Rheumatology Source Type: research

Autoantibodies in connective tissuedisease
Publication date: Available online 14 December 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ben Mulhearn, Sarah L. Tansley, Neil J. McHughAbstractAutoimmune connective tissue diseases are heterogeneous rheumatic diseases with the potential to affect multiple body systems. Autoantibodies are a characteristic feature of these diseases and are typically highly disease specific. In addition to aiding diagnosis, many autoantibodies have established associations with clinically important disease complications including internal organ involvement. In this chapter, we review the autoantibodies relevant ...
Source: Best Practice and Research Clinical Rheumatology - December 15, 2019 Category: Rheumatology Source Type: research

Editorial Board
Publication date: August 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 4Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - December 4, 2019 Category: Rheumatology Source Type: research

How to investigate: Very early inflammatory rheumatic diseases
Publication date: August 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 4Author(s): Luís Sousa Inês, László Czirják, Anisur Rahman (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - December 4, 2019 Category: Rheumatology Source Type: research

Index
Publication date: August 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 4Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - December 4, 2019 Category: Rheumatology Source Type: research

Pain without inflammation in rheumatic diseases
Publication date: June 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 3Author(s): Jon LampaAbstractChronic pain is a common symptom in rheumatic diseases, and the patient with pain and no signs of inflammation poses a challenge to the physician.Notably, all rheumatic diseases have components of non-inflammatory pain and a higher prevalence of fibromyalgia compared to the overall population.Hypothetically, a chronic pain stimulus may have stronger impact in a chronic inflammatory state, and the process towards a pain condition may be influenced by individual predisposition for development o...
Source: Best Practice and Research Clinical Rheumatology - November 7, 2019 Category: Rheumatology Source Type: research

Index
Publication date: June 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 3Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - November 7, 2019 Category: Rheumatology Source Type: research

Editorial Board
Publication date: June 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 3Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - November 7, 2019 Category: Rheumatology Source Type: research

Generalised musculoskeletal problems
Publication date: June 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 3Author(s): Christoph Baerwald, Ernest Choy (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - November 7, 2019 Category: Rheumatology Source Type: research

How to investigate: Pre-clinical rheumatoid arthritis
Publication date: Available online 15 October 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Patrícia Martins, João Eurico FonsecaAbstractMultiple studies have shown that there is a pre-clinical period preceding the development of rheumatoid arthritis (RA). During this period, complex interactions between the environmental and genetic causes occur, and the expression “preclinical RA” has been proposed to define it. Early treatment intervention is associated with less joint damage and has an increased possibility of achieving remission. In this review, we provide an overvi...
Source: Best Practice and Research Clinical Rheumatology - October 16, 2019 Category: Rheumatology Source Type: research

Myalgia in myositis and myopathies
Publication date: Available online 4 October 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Stefanie Glaubitz, Karsten Schmidt, Jana Zschüntzsch, Jens SchmidtAbstractMyalgia is a common symptom of various neuromuscular disorders: myalgia occurs in metabolic muscle diseases, inflammatory muscle diseases, dystrophic myopathies and myotonic muscle disorders. Myalgia leads to a significantly reduced quality of life. Other muscular symptoms that are present along with myalgia often provide the clue towards a diagnosis and include weakness, cramps and myotonia as well as the type of pain. In additi...
Source: Best Practice and Research Clinical Rheumatology - October 5, 2019 Category: Rheumatology Source Type: research

Suspected inflammatory rheumatic diseases in patients presenting with skin rashes
Publication date: Available online 1 October 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Francisca Alves, Margarida GonçaloAbstractSkin lesions occur, often at very early stages, in many of the most frequent inflammatory rheumatic diseases such as in systemic lupus erythematosus (SLE), dermatomyositis (DM), systemic sclerosis (SSc), Sjögren's syndrome, rheumatoid arthritis (RA), and psoriatic arthritis.It is important to recognize the different specific cutaneous lesions in SLE (e.g., “butterfly” rash in acute, annular or psoriasiform photosensitive lesions in the subacu...
Source: Best Practice and Research Clinical Rheumatology - October 2, 2019 Category: Rheumatology Source Type: research

How to investigate: Suspected systemic rheumatic diseases in patients presenting with muscle complaints
Publication date: Available online 26 September 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Irene Altabás-González, Naír Pérez-Gómez, José María Pego-ReigosaAbstractMuscular symptoms, which may be due to multiple causes, are one of the most common early complaints in a rheumatology practice. Musculoskeletal symptoms in rheumatic conditions are very varied, ranging from mechanical problems to muscular symptoms derived from inflammatory and systemic autoimmune diseases. Several drugs commonly used by different specialists and certain drugs used in ...
Source: Best Practice and Research Clinical Rheumatology - September 27, 2019 Category: Rheumatology Source Type: research

Interdisciplinary care of hip fractures.: Orthogeriatric models, alternative models, interdisciplinary teamwork
Publication date: April 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 2Author(s): Anette Hylen Ranhoff, Ingvild Saltvedt, Frede Frihagen, Johan Raeder, Sameer Maini, Olav SletvoldAbstractHip fractures are common among older people, and the prognosis is serious in terms of mobility, independence in daily life activities, and cognition, with 42% of patients never achieving the same function as before the fracture. Norway has the highest incidence of hip fractures, and the important tasks are to improve patient care and prevent new fractures.The aim was to develop Norwegian Guidelines for In...
Source: Best Practice and Research Clinical Rheumatology - September 21, 2019 Category: Rheumatology Source Type: research

Index
Publication date: April 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 2Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - September 21, 2019 Category: Rheumatology Source Type: research

Editorial Board
Publication date: April 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 2Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - September 21, 2019 Category: Rheumatology Source Type: research

Impact of fatigue on rheumatic diseases
Publication date: Available online 13 September 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Olga Seifert, Christoph BaerwaldAbstractFatigue is a common, disabling, and difficult-to-manage problem in rheumatic diseases. The concept of fatigue is difficult to define. No clear and widely accepted definition of fatigue is available. The symptoms of fatigue are defined as an overwhelming, debilitating, and sustained sense of exhaustion that decreases the ability to function and carry out daily activities. Prevalence estimates of fatigue within musculoskeletal diseases vary considerably (35%–82...
Source: Best Practice and Research Clinical Rheumatology - September 14, 2019 Category: Rheumatology Source Type: research

Sleep and rheumatic diseases
Publication date: Available online 11 September 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Tobias Boeselt, Rembert Koczulla, Christoph Nell, Bjoern Beutel, Konrad Guenther, Werner Cassel, Olaf Hildebrandt, Ulrich Koehler, Johannes KroenigAbstractThis review article discusses various forms of sleep disorders associated with musculoskeletal diseases (MD). It presents the pathophysiology and interaction of sleep-related disorders and MD and summarizes clinical symptoms and therapies from a somnological perspective.BackgroundA large number of patients suffering from MD report fragmented sleep with...
Source: Best Practice and Research Clinical Rheumatology - September 11, 2019 Category: Rheumatology Source Type: research

Taking the patient and the patient's perspective into account to improve outcomes of care of patients with musculoskeletal diseases
Publication date: Available online 6 September 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Martijn A.H. Oude Voshaar, Mart A.F.J. van de LaarAbstractPatient-reported outcome measures are commonly used in the assessment of patients with musculoskeletal diseases. The present review provides an overview of historic and recent developments, including core set recommendations for assessing patient-reported outcomes in patients with fibromyalgia, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis. The evidence supporting commonly used patient-reported outcomes measu...
Source: Best Practice and Research Clinical Rheumatology - September 8, 2019 Category: Rheumatology Source Type: research

Pain without inflammation
Publication date: Available online 6 September 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Jon LampaAbstractChronic pain is a common symptom in rheumatic diseases, and the patient with pain and no signs of inflammation poses a challenge to the physician.Notably, all rheumatic diseases have components of non-inflammatory pain and a higher prevalence of fibromyalgia compared to the overall population.Hypothetically, a chronic pain stimulus may have stronger impact in a chronic inflammatory state, and the process towards a pain condition may be influenced by individual predisposition for developme...
Source: Best Practice and Research Clinical Rheumatology - September 8, 2019 Category: Rheumatology Source Type: research

Very early systemic sclerosis
Publication date: Available online 3 September 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Silvia Bellando-Randone, Marco Matucci-CerinicAbstractThe early diagnosis of systemic sclerosis (SSc) can be very difficult, when most of the typical signs and symptoms are absent. For this reason, the approach to SSc has changed during the last decades because the importance of an early diagnosis and treatment has been widely understood. “Very early SSc” is identified as a condition characterized by Raynaud's phenomenon, puffy fingers, disease-specific autoantibodies, and microvascular altera...
Source: Best Practice and Research Clinical Rheumatology - September 5, 2019 Category: Rheumatology Source Type: research

Suspected systemic rheumatic diseases in adults presenting with fever
Publication date: Available online 29 August 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Dalia R. Ludwig, Tara N. Amin, Jessica J. MansonAbstractA significant proportion of patients with pyrexia of unknown origin (PUO) are found to have a rheumatological cause. The mainstay of treatment for rheumatic disease is immunosuppression, and therefore, accurate diagnosis is crucial given the risks associated with these drugs. In this review, we analyse the rheumatological conditions that most commonly present with fever and illustrate clinical cases demonstrating some of the challenges in the workup of...
Source: Best Practice and Research Clinical Rheumatology - August 30, 2019 Category: Rheumatology Source Type: research

Emerging role of eHealth in the identification of very early inflammatory rheumatic diseases
Publication date: Available online 27 August 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Suchitra Kataria, Vinod RavindranAbstractDigital health or eHealth technologies, notably pervasive computing, robotics, big-data, wearable devices, machine learning, and artificial intelligence (AI), have opened unprecedented opportunities as to how the diseases are diagnosed and managed with active patient engagement. Patient-related data have provided insights (real world data) into understanding the disease processes. Advanced analytics have refined these insights further to draw dynamic algorithms aidin...
Source: Best Practice and Research Clinical Rheumatology - August 29, 2019 Category: Rheumatology Source Type: research

Index
Publication date: February 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 1Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - August 18, 2019 Category: Rheumatology Source Type: research

Editorial Board
Publication date: February 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 1Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - August 18, 2019 Category: Rheumatology Source Type: research

Prevention, management and long-term consequences of sport and exercise-related musculoskeletal disorders
Publication date: February 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 1Author(s): Jackie L. Whittaker, Carly D. McKay, Mark E. Batt (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - August 18, 2019 Category: Rheumatology Source Type: research

Index
Publication date: December 2018Source: Best Practice & Research Clinical Rheumatology, Volume 32, Issue 6Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - August 17, 2019 Category: Rheumatology Source Type: research

Practical issues in the modern management of rheumatic disease
Publication date: December 2018Source: Best Practice & Research Clinical Rheumatology, Volume 32, Issue 6Author(s): Joseph Markenson, Peter Nash (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - August 17, 2019 Category: Rheumatology Source Type: research

Management of hepatitis B and C infections in rheumatologic disease
Publication date: December 2018Source: Best Practice & Research Clinical Rheumatology, Volume 32, Issue 6Author(s): Jonathan TL. Cheah, John J. Faragon, Kristen M. MarksAbstractHepatitis B and C viruses present dual considerations in rheumatic disease as both etiologic factors and important comorbidities that must be assessed and addressed. This review summarizes the link between hepatitis B and arthritis and polyarteritis nodosa as well as hepatitis C and arthritis, Sicca syndrome and cryoglobulinemic vasculitis. Recent data pertaining to the antiviral management in these conditions, especially regarding the use of th...
Source: Best Practice and Research Clinical Rheumatology - August 17, 2019 Category: Rheumatology Source Type: research

Editorial Board
Publication date: December 2018Source: Best Practice & Research Clinical Rheumatology, Volume 32, Issue 6Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - August 17, 2019 Category: Rheumatology Source Type: research

Fragility fractures – Global call to action
Publication date: Available online 8 August 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Karsten E. Dreinhöfer (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - August 10, 2019 Category: Rheumatology Source Type: research

How to investigate: Early axial spondyloarthritis
Publication date: Available online 31 July 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Pedro D. Carvalho, Pedro M. MachadoAbstractAxial spondyloarthritis (axSpA) is a chronic inflammatory condition of the axial skeleton that encompasses radiographic and non-radiographic axSpA and that can lead to chronic pain, structural damage, disability, and loss of quality of life. Scientific advances, including the role of MRI assessment, have led to new diagnostic insights and the creation of a new set of classification criteria for axial and peripheral SpA. New criteria allow the identification of SpA pa...
Source: Best Practice and Research Clinical Rheumatology - August 1, 2019 Category: Rheumatology Source Type: research

Management of difficult osteoporosis
Publication date: Available online 25 July 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Linda A. RussellAbstractOsteoporosis and associated low-impact fractures are common. There is associated morbidity and mortality with low-impact fractures. It is critical to identify which patients would benefit from therapy. General treatment considerations are reviewed. Currently available treatment options are discussed. Certain patient populations pose challenges in the treatment of osteoporosis. An in-depth review of clinically challenging scenarios is presented: Treatment of patients with severe osteopo...
Source: Best Practice and Research Clinical Rheumatology - July 26, 2019 Category: Rheumatology Source Type: research