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'Exercise pill' could potentially help people with heart failure

Conclusion The protein hCT1 caused heart muscles to grow in a more healthy way in rodents with heart failure. When treatment stopped, the heart went back to its original condition – something that does not happen when the heart grows in a dysfunctional way. There is currently no cure for heart failure and treatment is only available for keeping symptoms under control. Therefore, this very promising early-stage research with potential for developing a drug for people with heart failure, has huge implications. However, it is important to remember that as this is experimental laboratory research, there are many more stages and hurdles to clear before a drug could become available. Something that works for rats and mice will not necessarily work for humans as we are anatomically different and biological processes do not happen in exactly the same way. It may also cause future side effects that were not apparent in these short-term laboratory experiments. If you have been diagnosed with heart failure, follow your doctor's advice on how you can relieve your symptoms, reduce your risk of complications and improve your overall quality of life. Read more about treating and living with heart failure. Links To The Headlines Pill that mimics effects of going to the gym could transform lives of heart failure patients. Daily Mirror, August 9 2017 Heart disease: 'Exercise pill' that mimics effects of visit to the gym could improve lives. Daily Express, August 9 20...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Source Type: news

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Results from experiments on mice with cerebral ischemia are promising and produce blood-flow images that are comparable to those obtained with MRI, but in real time.
Source: Nanotechweb.org News - Category: Nanotechnology Authors: Source Type: news
Phys. Chem. Chem. Phys., 2017, Accepted Manuscript DOI: 10.1039/C7CP05565J, PaperBo Richter, Dorthe Ravnsbaek, Manish Sharma, Alexandra Spyratou Stratmann, Hans Hagemann, Torben Rene R. Jensen Fluoride substitution in LiBH4 is studied by investigation of LiBH4-LiBF4 mixtures (9:1 and 3:1). Decomposition was followed by in-situ synchrotron radiation X-ray diffraction (in-situ SR-PXD), thermogravimetric analysis and differential scanning... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - Category: Chemistry Authors: Source Type: research
Green Chem., 2017, Accepted Manuscript DOI: 10.1039/C7GC02304A, PaperLong-Yong Xie, Yong-Jian Li, Jie Qu, Yue Duan, Jue Hu, Kai-Jian Liu, Zhong Cao, Wei-Min He Without employing any base and organic solvent, an economical, practical and eco-friendly protocol has been developed for the one-pot synthesis of various functionalized 2-sulfonylquinolines from easily accessible starting materials on... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Green Chem. latest articles - Category: Chemistry Authors: Source Type: research
Authors: Dutra S, Gomes FV, Bilhim T, Coimbra É Abstract The authors present a case of a 39-year-old man with alcoholic chronic pancreatitis that was admitted in the emergency department after a car accident, complaining of abdominal pain and looking pale. The patient was hemodinamically unstable, requiring blood transfusions. He underwent computed tomography angiogram of the abdomen and pelvis, showing a pseudoaneurysm of the gastroduodenal artery and a hemoperitoneum. He was referred to our interventional radiology unit and submitted to endovascular treatment, consisting of 'backdoor' and 'frontdoor' embol...
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
We describe a case referred as a degenerating fibroid, with a negative urinary pregnancy test. Transvaginal ultrasound was highly suggestive of molar pregnancy, which was confirmed with a quantitative βhCG test, allowing for timely treatment. The importance of a high index of suspicion for this pathology is tremendous to avoid the devastating consequences of a delayed diagnosis. PMID: 29025533 [PubMed - in process]
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
CONCLUSION: The radiologist can better manage the required radiological examinations, effectively screening within a multidisciplinary team environment, promoting the development and supporting the respect of guidelines, and potentially reducing requests through opinions or second opinions. PMID: 29025529 [PubMed - in process]
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
Conclusion: A loss of lung aeration during the spontaneous breathing trial in non-dependent lung zones was demonstrated in subjects who failed to wean.
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
Conclusion: This Latin American prospective cohort investigation confirmed specific factors important for the development of delirium and the outcome of death among general intensive care unit patients. In both analyses, we found that the duration of mechanical ventilation was a predictor of untoward outcomes.
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
Authors: Maisch B Abstract The individual amount of alcohol consumed acutely or chronically decides on harm or benefit to a person's health. Available data suggest that one to two drinks in men and one drink in women will benefit the cardiovascular system over time, one drink being 17.6 ml 100 % alcohol. Moderate drinking can reduce the incidence and mortality of coronary artery disease, heart failure, diabetes, ischemic and hemorrhagic stroke. More than this amount can lead to alcoholic cardiomyopathy, which is defined as alcohol toxicity to the heart muscle itself by ethanol and its metabolites. Histo...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
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