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'Exercise pill' could potentially help people with heart failure

Conclusion The protein hCT1 caused heart muscles to grow in a more healthy way in rodents with heart failure. When treatment stopped, the heart went back to its original condition – something that does not happen when the heart grows in a dysfunctional way. There is currently no cure for heart failure and treatment is only available for keeping symptoms under control. Therefore, this very promising early-stage research with potential for developing a drug for people with heart failure, has huge implications. However, it is important to remember that as this is experimental laboratory research, there are many more stages and hurdles to clear before a drug could become available. Something that works for rats and mice will not necessarily work for humans as we are anatomically different and biological processes do not happen in exactly the same way. It may also cause future side effects that were not apparent in these short-term laboratory experiments. If you have been diagnosed with heart failure, follow your doctor's advice on how you can relieve your symptoms, reduce your risk of complications and improve your overall quality of life. Read more about treating and living with heart failure. Links To The Headlines Pill that mimics effects of going to the gym could transform lives of heart failure patients. Daily Mirror, August 9 2017 Heart disease: 'Exercise pill' that mimics effects of visit to the gym could improve lives. Daily Express, August 9 20...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Source Type: news

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Speckle tracking imaging in hypertrophic cardiomyopathy : A powerful tool in search of an unfavorable substrate? Herz. 2017 Dec 12;: Authors: Rigopoulos AG, Ali M, Sakellaropoulos S, Matiakis M, Teren M, Pantazis A, Noutsias M PMID: 29234844 [PubMed - as supplied by publisher]
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
CONCLUSION: Increased cyclic right atrial volumes and mild alterations in right atrial functional properties could be demonstrated in idiopathic hypereosinophilic syndrome patients. PMID: 29234843 [PubMed - as supplied by publisher]
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
Authors: Schlitt A, Guha M, Noutsias M, Klein HH, Klein HU Abstract Assessment of a permanent risk of life-threatening ventricular arrhythmia in patients with severely reduced left ventricular ejection fraction (LVEF
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
In conclusion, hypothyroidism due to thyroid developmental anomaly should be taken into consideration in case of hypothyroidism and normal thyroid autoantibodies in a patient at any age. PMID: 29238947 [PubMed - in process]
Source: Endokrynologia Polska - Category: Endocrinology Authors: Tags: Endokrynol Pol Source Type: research
In this report, we describe the first case, to our knowledge, of congenital Zika syndrome with concomitant critical congenital heart disease. The mother had a confirmed ZIKV infection in the first trimester of pregnancy. Fetal ultrasonography at 31 weeks of gestation revealed cerebral cortical calcifications and hypoplastic left heart syndrome. The severity of brain involvement was assessed by postnatal magnetic resonance imaging and echocardiogram, and palliative surgery was performed. The ethical dimensions of this infant's clinical management are discussed. ZIKV is known to affect neural progenitor cells, but whether it...
Source: Neonatology - Category: Perinatology & Neonatology Source Type: research
Mysterious object detected hurtling through our solar system swept for radio signals, but scientists have found no evidence it is anything other than rockThe first scans for alien technology aboard a mysterious object that is barreling through the solar system have found no evidence it is the work of an intelligent civilisation.The cigar-shaped object was spotted hurtling through the solar systemin October and while astronomers suspected it was an interstellar asteroid, its curious shape led them to propose sweeping it for radio signals in case it happened to be an alien craft.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Space Alien life Astronomy Science Asteroids Source Type: news
We describe an anticoagulant-free off-pump LVAD implant technique to circumvent potential complications associated with conventional approaches. This technique is safe and is probably the least invasive surgical approach for LVAD implantation. PMID: 29233363 [PubMed - in process]
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
We report a case of a 69-year-old woman who required an apicoaortic bypass conduit after stenosis of a biological aortic prosthesis valve previously implanted 4 years earlier. The patient was admitted to the emergency department 8 years later with a diagnosis of congestive heart failure. Echocardiography and nuclear magnetic resonance revealed severe regurgitation of the conduit valve. Because the patient had a very high Society of Thoracic Surgeons risk score associated to an acute angle between the aorta artery and the apicoaortic conduit, we decided to perform an antegrade and direct transcatheter valve-in-valve implant...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
Time limit: 0 Quiz-summary 0 of 20 questions completed Questions: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Information This test series requires login for attempting. You can login easily with your Facebook account (Use the CONNECT WITH icon on the upper part of right sidebar displaying t...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs
Authors: Maisch B Abstract The individual amount of alcohol consumed acutely or chronically decides on harm or benefit to a person's health. Available data suggest that one to two drinks in men and one drink in women will benefit the cardiovascular system over time, one drink being 17.6 ml 100 % alcohol. Moderate drinking can reduce the incidence and mortality of coronary artery disease, heart failure, diabetes, ischemic and hemorrhagic stroke. More than this amount can lead to alcoholic cardiomyopathy, which is defined as alcohol toxicity to the heart muscle itself by ethanol and its metabolites. Histo...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
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