• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Unilateral basal ganglia restricted diffusion in anti ‐leucine‐rich glioma‐inactivated 1 encephalitis mimicking cerebral infarction: A report on two cases and literature review
ConclusionOur report adds to the heterogeneity of anti-leucine-rich glioma-inactivated  1 encephalitis and highlights the need to consider this diagnosis in patients who present atypically.
Source: Clinical and Experimental Neuroimmunology - July 23, 2021 Category: Neurology Authors: Mervyn Q. W. Poh, Hui Jin Chiew, Zheyu Xu, Kevin Tan, Tchoyoson C. C. Lim, Tianrong Yeo Tags: CASE REPORT Source Type: research

Meningioma preceding CASPR2 antibody limbic encephalitis with a stroke mimic: A case report
We report a contactin-associated protein-like 2-antibody (CASPR2-Ab)-positive patient who presented with atypical LE. Diagnoses: CASPR2-Ab-positive LE was the presumed diagnosis. Re-evaluation of cerebrospinal fluid (CSF) samples revealed autoantibodies targeting CASPR2 at an immunoglobulin G titer of 1:1. The clinical presentation of subacute onset seizures, abnormal electroencephalography, hypermetabolism on positron emission tomography, good immunotherapy response, and the presence of specific antibodies in serum supports a diagnosis of autoimmune LE. Intervention: The patient received glucocorticoids (1�...
Source: Medicine - June 11, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Clinical and radiological aspects of bilateral temporal abnormalities: pictorial essay
Abstract The temporal lobes are vulnerable to several diseases, including infectious, immune-mediated, degenerative, vascular, metabolic, and neoplastic processes. Therefore, lesions in the temporal lobes can pose a diagnostic challenge for the radiologist. The temporal lobes are connected by structures such as the anterior commissure, corpus callosum, and hippocampal commissure. That interconnectedness favors bilateral involvement in various clinical contexts. This pictorial essay is based on a retrospective analysis of case files from a tertiary university hospital and aims to illustrate some of the conditions that simul...
Source: Radiologia Brasileira - March 26, 2021 Category: Radiology Source Type: research

Mild Encephalitis/Encephalopathy with a Reversible Splenial Lesion in an Adult with Cerebellar Ataxia: A Case Report.
Abstract Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinicoradiological syndrome characterized by transient mild encephalopathy and magnetic resonance imaging (MRI) findings of a reversible lesion in the splenium of the corpus callosum (SCC). Patients with MERS generally present with central nervous system symptoms such as consciousness disturbance, headache, and seizure; adult-onset MERS with cerebellar ataxia is rare. A 53-year-old man was admitted to our hospital with fever of 1 week's duration, headache, neck stiffness, and gait disturbance. Neurological examination revealed...
Source: Journal of Nippon Medical School - July 15, 2020 Category: Universities & Medical Training Authors: Nakajima M, Suda S, Kimura K Tags: J Nippon Med Sch Source Type: research

Unilateral Cortical Fluid-Attenuated Inversion Recovery –Hyperintense Lesions in Anti-Myelin Oligodendrocyte Glycoprotein–Associated Encephalitis With Seizures (FLAMES): An Under-recognized Entity
We read with interest the article by Tutmaher et  al.1 They report an 11-year-old girl with acute-onset right hemiparesis concerning for stroke. Brain magnetic resonance imaging revealed mild left frontoparietal cortical T2-weighted fluid-attenuated inversion recovery (FLAIR) hyperintensity. She was ultimately diagnosed with myelin oligodendrocyt e glycoprotein-immunoglobulin G (MOG-IgG)–associated disease (MOGAD). MOGAD is a recently recognized subset of central nervous system inflammatory demyelinating diseases, to which children and young adults seem particularly predisposed.
Source: Pediatric Neurology - May 10, 2020 Category: Neurology Authors: Adrian Budhram, Ario Mirian, Eoin P. Flanagan Tags: Correspondence Source Type: research

Unilateral cortical FLAIR-hyperintense Lesions in Anti-MOG Encephalitis with Seizures (FLAMES): An under-recognized entity
We read with interest the article by Tutmaher et al.(1). The authors report an 11-year-old girl with acute-onset right hemiparesis concerning for stroke. Brain magnetic resonance imaging (MRI) revealed mild left fronto-parietal cortical T2-fluid-attenuated inversion recovery (FLAIR) hyperintensity. She was ultimately diagnosed with myelin oligodendrocyte glycoprotein (MOG)-IgG-associated disease (MOGAD). MOGAD is a recently recognized subset of central nervous system inflammatory demyelinating diseases, to which children and young adults seem particularly pre-disposed(2).
Source: Pediatric Neurology - May 10, 2020 Category: Neurology Authors: Adrian Budhram, Ario Mirian, Eoin P. Flanagan Tags: Correspondence Source Type: research

A Case of Multiple Sclerosis —Like Relapsing Remitting Encephalomyelitis Following Allogeneic Hematopoietic Stem Cell Transplantation and a Review of the Published Literature
Complications involving the central nervous system (CNS) occur in 9–14% of patients following allogeneic hematopoietic stem cell transplantation (HSCT), including stroke-like episodes, demyelination, encephalitis, and nonspecific neurological symptoms. Here we report a case of multiple sclerosis (MS) like relapsing remitting encephalomyelitis following allogeneic HSCT, which did not respond to disease modifying therapies (DMTs) and “domino” autologous HSCT. A 53-year-old male was treated with allogeneic HSCT for lymphoid blast transformation of chronic myeloid leukemia. Ten months later he presented with confusion, s...
Source: Frontiers in Immunology - May 4, 2020 Category: Allergy & Immunology Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

New-Onset Geriatric Epilepsy in China: A Single-Center Study.
Conclusions: Autoimmune encephalitis is becoming an increasing risk factor of subsequent epilepsy in older people. Older patients with new epilepsy are more likely to respond to antiepileptic drugs, and drug-resistant epilepsy is uncommon. PMID: 30539903 [PubMed - in process]
Source: Chinese Medical Journal - December 14, 2018 Category: General Medicine Authors: Chen JH, Zhou XQ, Lu Q, Jin LR, Huang Y Tags: Chin Med J (Engl) Source Type: research

Magnetic resonance imaging of arterial stroke mimics: a pictorial review
AbstractAcute ischaemic stroke represents the most common cause of new sudden neurological deficit, but other diseases mimicking stroke happen in about one-third of the cases. Magnetic resonance imaging (MRI) is the best technique to identify those ‘stroke mimics’. In this article, we propose a diagnostic approach of those stroke mimics on MRI according to an algorithm based on diffusion-weighted imaging (DWI), which can be abnormal or normal, followed by the results of other common additional MRI sequences, such as T2 with gradient recall ed echo weighted imaging (T2-GRE) and fluid-attenuated inversion recovery (FLAIR...
Source: Insights into Imaging - June 22, 2018 Category: Radiology Source Type: research

Neurological Disorders Associated with Human Alphaherpesviruses.
Authors: Kawada JI Abstract Herpes simplex virus (HSV) encephalitis is the most common cause of sporadic fatal encephalitis worldwide, and central nervous system (CNS) involvement is observed in approximately one-third of neonatal HSV infections . In recent years, single-gene inborn errors of innate immunity have been shown to be associated with susceptibility to HSV encephalitis . Temporal lobe abnormalities revealed by magnetic resonance imaging-the most sensitive imaging method for HSV encephalitis-are considered strong evidence for the disease. Detection of HSV DNA in the cerebrospinal fluid by polymerase chain...
Source: Advances in Experimental Medicine and Biology - June 15, 2018 Category: Research Tags: Adv Exp Med Biol Source Type: research

Letter to the Editor: Pneumocephalus: Is the needle size significant?
Discussion. Pneumocephalus is defined by two mechanisms: a ball-valve and an inverted bottle concept.1 The ball-valve type implies positive pressure events, such as coughing or valsalva maneuvers, that prevent air escape. Tension pneumocephalus is included in this mechanism, causing a parenchymal mass effect. The inverted bottle theory includes a negative intracranial pressure gradient following cerebrospinal fluid drainage, relieved by air influx. A small pneumocephalus is usually sealed by blood clots or granulation, allowing spontaneous reabsorption and resolution.[1] Otherwise, the lateral positioning of a patient duri...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools CNS Infections Current Issue Letters to the Editor Neurologic Systems and Symptoms Neurology Stroke Traumatic Brain Injury epidural needle size Pneumocephalus spinal tap Source Type: research

Acquired hepatocerebral degeneration (AHD): a peculiar neurological impairment in advanced chronic liver disease
AbstractWe discuss the case of a rare and often unrecognized neurologic syndrome, called Acquired Hepatocerebral Degeneration (AHD), observed in patients with advanced liver disease and portosystemic shunts. The clinical manifestations can be very heterogeneous and in our case included a combination of cerebellar and extrapyramidal signs, arisen in a period of few days. Brain Magnetic Resonance Imaging (MRI) showed, in T1-weighted images, diffuse bilateral hyper intensities in basal ganglia and biemispheric brain and cerebellar cortices, resembling paramagnetic deposits. No other neurological impairments, like stroke, infe...
Source: Metabolic Brain Disease - January 15, 2018 Category: Neurology Source Type: research

Does restricted diffusion in the splenium indicate an acute infarct?
ConclusionNot every diffuse restriction observed on MRI indicates an ischemic stroke. Although radiologic images of the splenium may suggest acute ischemic infarction, the actual cause may be another pathology. Therefore, the symptoms and aetiologies of patients with splenium lesions should be considered and investigated from a wide range of perspectives.
Source: Acta Neurologica Belgica - January 6, 2018 Category: Neurology Source Type: research

Misdiagnosis of CADASIL: A single Medical Center experience (P1.251)
Conclusions:CADASIL is the most prevalent monogenic cerebral small-vessel arteriopathy. Despite wide availability of genetic testing, misdiagnosis and delay diagnosis are common. We encourage for enhanced awareness of CADASIL among patients with migraines with aura, recurrent TIAs or subcortical ischemic strokes, and mood disorder, in order to provide appropriate multidisciplinary treatment, psychological support and genetic counselingStudy Supported by: n/aDisclosure: Dr. Ortiz-Garcia has nothing to disclose. Dr. Orjuela has nothing to disclose. Dr. Sweis has nothing to disclose. Dr. Biller has received personal compensat...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ortiz-Garcia, J., Orjuela, K., Sweis, R., Biller, J. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10