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Total 356 results found since Jan 2013.

Pediatric obesity: Causes, symptoms, prevention and treatment.
Authors: Xu S, Xue Y Abstract Pediatric or childhood obesity is the most prevalent nutritional disorder among children and adolescents worldwide. Approximately 43 million individuals are obese, 21-24% children and adolescents are overweight, and 16-18% of individuals have abdominal obesity. The prevalence of obesity is highest among specific ethnic groups. Obesity increases the risk of heart diseases in children and adults. Childhood obesity predisposes the individual to insulin resistance and type 2 diabetes, hypertension, hyperlipidemia, liver and kidney diseases and causes reproductive dysfunction in adults. Obe...
Source: Experimental and Therapeutic Medicine - February 4, 2016 Category: Journals (General) Tags: Exp Ther Med Source Type: research

Cannabinoid pharmacology in cancer research: A new hope for cancer patients?
Abstract Cannabinoids have been used for many centuries to ease pain and in the past decade, the endocannabinoid system has been implicated in a number of pathophysiological conditions, such as mood and anxiety disorders, movement disorders such as Parkinson's and Huntington's disease, neuropathic pain, multiple sclerosis, spinal cord injury, atherosclerosis, myocardial infarction, stroke, hypertension, glaucoma, obesity, and osteoporosis. Several studies have demonstrated that cannabinoids also have anti-cancer activity and as cannabinoids are usually well tolerated and do not produce the typical toxic effects of...
Source: European Journal of Pharmacology - February 4, 2016 Category: Drugs & Pharmacology Authors: Javid FA, Phillips RM, Afshinjavid S, Verde R, Ligresti A Tags: Eur J Pharmacol Source Type: research

Palliative care in India: Situation assessment and future scope
SS Kar, L Subitha, S IswaryaIndian Journal of Cancer 2015 52(1):99-101Palliative care is an approach that improves the quality of life of patients and their families facing the problems associated with life-threatening illness, through prevention and relief of suffering by means of early identification, assessment and treatment of pain, and other problems – physical, psychosocial, and spiritual. It is estimated that in India the total number of people who need palliative care is likely to be 5.4 million people a year. Though palliative care services have been in existence for many years, India ranks at the bot...
Source: Indian Journal of Cancer - February 3, 2016 Category: Cancer & Oncology Authors: SS KarL SubithaS Iswarya Source Type: research

Severe Cerebral Vasospasm and Childhood Arterial Ischemic Stroke After Intrathecal Cytarabine
We report on 2 patients who developed widespread cerebral vasospasm and arterial ischemic strokes (AIS) after application of intrathecal (IT) cytarabine. In a 3-year-old child with acute lymphoblastic leukemia (ALL), left leg weakness, hyperreflexia, and clonus were noted 4 days after her first dose of IT cytarabine during the induction phase of her chemotherapy. Cerebral MRI revealed multiple acute cerebral ischemic infarcts and widespread cerebral vasospasm. A 5-year-old girl complained of right arm and leg pain and began limping 11 days after IT cytarabine. Symptoms progressed to right dense hemiplegia, left gaze deviat...
Source: PEDIATRICS - February 1, 2016 Category: Pediatrics Authors: Tibussek, D., Natesirinilkul, R., Sun, L. R., Wasserman, B. A., Brandao, L. R., deVeber, G. Tags: Hematology/Oncology, Cancer/Neoplastic, Neurology, Neurologic Disorders Case Report Source Type: research

Short- and long-term effects of smoking on pain and health-related quality of life after non-instrumented lumbar spine surgery
Smoking is commonly known to exert negative effects on bodily health such as a 25-fold increased risk for lung cancer, a 2- to 4-fold increased risk for coronary heart disease or stroke [1], as well as to represent a cause of premature death [2]. In Germany for example, more than 114.000 premature deaths, 1.6 million years of potential life lost and 21 billion Euros are the socio-economic burden of smoking [3]. Despite these well-known risks, the smoking prevalence is still high and varies greatly across different European countries from as low as 19.7% in Portugal to as high as 45.7% in Bulgaria [4].
Source: Clinical Neurology and Neurosurgery - January 20, 2016 Category: Neurosurgery Authors: Martin N. Stienen, Holger Joswig, Nicolas R. Smoll, Enrico Tessitore, Karl Schaller, Gerhard Hildebrandt, Oliver P. Gautschi Source Type: research

Anticoagulant treatment for subsegmental pulmonary embolism.
CONCLUSIONS: There is no randomised controlled trial evidence for the effectiveness and safety of anticoagulation therapy versus no intervention in patients with isolated subsegmental pulmonary embolism (SSPE) or incidental SSPE, and therefore we can not draw any conclusions. Well-conducted research is required before informed practice decisions can be made. PMID: 26756331 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - January 12, 2016 Category: Journals (General) Authors: Yoo HH, Queluz TH, El Dib R Tags: Cochrane Database Syst Rev Source Type: research

Long-term outcomes of the bronchial artery embolization are diagnosis dependent
Conclusions: The BAE is a safe and effective procedure with excellent overall long-term survival.
Source: Lung India - January 4, 2016 Category: Respiratory Medicine Authors: Vikas PathakJoseph M StavasHubert J FordCharles A AustinRobert M Aris Source Type: research

Optimising palliative and end-of-life care within care home settings
Background The World Health Organization (WHO) has defined palliative care as an approach that improves the quality of life of patients and their families facing the problems associated with life-threatening illness, through the prevention and relief of suffering by means of early identification and impeccable assessment and treatment of pain and other problems, physical, psychosocial and spiritual.1 Globally, it is estimated that every year over 20 million people will require palliative care at the end of life. Of these 69% are adults over 60 years. These older population, who make up the vast majority of residents w...
Source: Evidence-Based Nursing - December 15, 2015 Category: Nursing Authors: Mitchell, G., Twycross, A. Tags: End of life decisions (geriatric medicine), Drugs: cardiovascular system, Dementia, Pain (neurology), EBN Opinion, Stroke, End of life decisions (palliative care), Hospice, Memory disorders (psychiatry), End of life decisions (ethics) Source Type: research

Guideline of neuropathic pain treatment and dilemma from neurological point of view.
Authors: Yang CM, Chen NC, Shen HC, Chou CH, Yeh PS, Lin HJ, Chang CY, Cheng TJ, Lin KC Abstract Neuropathic pain is a complicated symptomatic disease as migraine in recent years. Not because the pain character differed from the nociceptive inflammatory symptoms but because of its complexity of mechanisms. Though peripheral sensitization, ectopic discharge, central sensitization, central re-organization and loss of inhibition play part of roles in mechanisms, however, based on this mechanistic treatment, the outcome still disappointed physicians and patients, exampled as central post-stroke central pain (CPSP). The...
Source: Acta Neurologica Taiwanica - December 12, 2015 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

$10 million gift to UCLA from Wendy and Leonard Goldberg is largest ever to support migraine research
UCLA Health Sciences has received a $10 million gift, most of which will support multidisciplinary research on migraine, a debilitating neurological disorder that affects 36 million people in the U.S. The gift was made by philanthropists Wendy and Leonard Goldberg. Wendy Goldberg is an editor and author; her husband, Leonard, is an award-winning film and television producer and executive. More than 90 percent of sufferers are unable to work during their migraine attacks, costing employers $13 billion a year in lost work days; and every 10 seconds, someone in the U.S. goes to an emergency room with a migraine-related compla...
Source: UCLA Newsroom: Health Sciences - December 8, 2015 Category: Universities & Medical Training Source Type: news

Patient preference and decision-making for initiating metastatic colorectal cancer medical treatment.
CONCLUSIONS: Variations in patients' willingness to tolerate different treatment-related adverse events underscore the need for improved communications between physicians and patients about the risks and benefits of their medical treatment, which helps make a more personalized decision for metastatic CRC treatment. PMID: 26577827 [PubMed - as supplied by publisher]
Source: Clinical Colorectal Cancer - November 18, 2015 Category: Cancer & Oncology Authors: Fu AZ, Graves KD, Jensen RE, Marshall JL, Formoso M, Potosky AL Tags: J Cancer Res Clin Oncol Source Type: research

Patient preference and decision-making for initiating metastatic colorectal cancer medical treatment
Conclusions Variations in patients’ willingness to tolerate different treatment-related adverse events underscore the need for improved communications between physicians and patients about the risks and benefits of their medical treatment, which helps make a more personalized decision for metastatic CRC treatment.
Source: Journal of Cancer Research and Clinical Oncology - November 18, 2015 Category: Cancer & Oncology Source Type: research

Healing through music
The last time I had a mammogram, I got a big surprise — and it was a good one. A string quartet was playing just outside the doors of the breast imaging center, and my thoughts immediately shifted from “What are they going to find on the mammogram?” to “Is that Schubert, or Beethoven?” By the time my name was called, I had almost forgotten why I was there. The unexpected concert was the work of Holly Chartrand and Lorrie Kubicek, music therapists and co-coordinators of the Environmental Music Program at Massachusetts General Hospital. But bringing music to hospital corridors is just a sideline for music therapist...
Source: New Harvard Health Information - November 5, 2015 Category: Consumer Health News Authors: Beverly Merz Tags: Behavioral Health Mental Health Pain Management Surgery Source Type: news

10 Scary Ways Your Office Job Is Killing You
This article originally appeared on YourTango. More from YourTango: Why I'm Giving Up My Cushy Job To Travel The World In An RV 7 Ways To Keep Their Passive-Aggression From Driving You Nuts 10 Uplifting Quotes That Will Get You Through The Day 5 Things You MUST Try Before Turning To Mood-Boosting Medicines Quotes To Share With Your Long-Distance Lover Also on HuffPost: -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - October 28, 2015 Category: Consumer Health News Source Type: news

Risk of type 2 diabetes mellitus in female breast cancer patients treated with morphine: a retrospective population-based time-dependent cohort study
A key element of the palliative care of cancer patients is the management of chronic pain [1]. Opioids continue to be a mainstay in the management of cancer pain in all treatment guidelines [2], and morphine is regarded as the “gold standard” [3–6]. Considered as broad-spectrum analgesics, opioids have multiple side effects and potential complications [7]. Our previous studies indicated that morphine treatment is associated with subdural hemorrhage [8], pulmonary embolism [9], and acute coronary syndrome [10] in cancer patients, as well as increased stroke incidence in prostate cancer patients [11].
Source: Diabetes Research and Clinical Practice - October 12, 2015 Category: Endocrinology Authors: Szu-Pang Yang, Chih-Hsin Muo, I-Kuan Wang, Yen-Jung Chang, Shih-Wei Lai, Cynthia Wei-Sheng Lee, Donald E. Morisky Source Type: research