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Condition: Hemorrhagic Stroke
Cancer: Cancer

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Total 421 results found since Jan 2013.

Endovascular Therapy of Acute Ischemic Stroke in Patients with Large-Vessel Occlusion Associated with Active Malignancy
Approximately 15% of cancer patients have concomitant cerebrovascular disease.1,2 The frequency of ischemic and hemorrhagic stroke in this group of patients is similar to the general population2, and about one in ten stroke patients may have a concurrent malignancy.3 Intravenous thrombolysis (IVT) in these patients is often contraindicated and is used less frequently due to various possible comorbidities.4 While EVT is a well-established approach to treat acute ischemic stroke (AIS) secondary to large vessel occlusion (LVO) 5,6,7,8, there is paucity of data with regards to EVT success and outcomes in patients with active malignancy.
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2020 Category: Neurology Authors: Tomohiko Ozaki, Patrick Nicholson, Joanna D. Schaafsma, Ronit Agid, Timo Krings, Aleksandra Pikula, Vitor Mendes Pereira Source Type: research

Machine learning boosts chest CT's performance
Machine learning-based CT texture analysis software improves reader accuracy...Read more on AuntMinnie.comRelated Reading: AI can quantify hematoma in hemorrhagic stroke patients Large study confirms value of CT lung cancer screening CT radiation doses for COVID-19 patients vary widely CT lung screening scans also work for bone density CT lung screening program falls short in China
Source: AuntMinnie.com Headlines - November 18, 2020 Category: Radiology Source Type: news

Direct oral anticoagulants versus vitamin K antagonists in patients with atrial fibrillation and cancer a meta-analysis
ConclusionsIn comparison to VKA, DOACs were associated with a significant reduction of the rates of thromboembolic events and major bleeding complications in patients with AF and cancer. Further studies are needed to confirm our results.
Source: Journal of Thrombosis and Thrombolysis - October 12, 2020 Category: Hematology Source Type: research

Fried-Food Consumption Does Not Increase the Risk of Stroke in the Spanish Cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC) Study
ConclusionsIn this Spanish cohort, whose participants mainly used olive oil or sunflower oil when frying, the consumption of fried food was not associated with an increased risk of incident stroke.
Source: Journal of Nutrition - September 16, 2020 Category: Nutrition Source Type: research

Efficacy and safety of intravenous thrombolysis for acute ischemic stroke in cancer patients: a systemic review and meta-analysis.
Authors: Huang S, Lu X, Tang LV, Hu Y Abstract The efficacy and safety of intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) in cancer patients remained uncertain due to low level evidence in the latest guideline for AIS. The aim of this study was to assess the efficacy and safety of IVT in cancer patients with stronger evidence. We searched Medline, Embase, CENTRAL and ClinicalTrials.gov until April 2020 for studies reporting outcomes of functional independence, hemorrhagic transformation (HT), symptomatic intracranial hemorrhage (SICH), major bleeding (MB), in-hospital mortality or 3-month mortality a...
Source: American Journal of Translational Research - September 13, 2020 Category: Research Tags: Am J Transl Res Source Type: research

Nationwide Patterns of Hemorrhagic Stroke among Patients Hospitalized with Brain Metastases: Influence of Primary Cancer Diagnosis and Anticoagulation
Brain metastases can contribute to a decreased quality of life for patients with cancer, often leading to malaise, neurologic dysfunction, or death. Intracerebral hemorrhage (ICH) is especially feared complication in patients with brain metastases given the potential for significant morbidity and mortality.
Source: International Journal of Radiation Oncology * Biology * Physics - September 10, 2020 Category: Radiology Authors: Henry Park, Victor Lee, Vikram Jairam, James Yu Source Type: research

Direct oral anticoagulants: In which indications? Which one to prescribe? For or against their use in frail patients and in atypical cases? Which monitoring and management haemorrhage complications?
Authors: Hoffmann C, Leven C, Le Mao R, De Moreuil C, Lacut K Abstract Since their approval, the direct oral anticoagulants have been widely used in the management of venous thromboembolism, for stroke and systemic embolism prevention in non valvular atrial fibrillation, and in venous thromboembolism prophylaxis after surgical hip or knee replacement. Because they are easy to use, with oral fixed doses and no biological monitoring need, they are more and more prescribed. New indications are rising in cancer associated thrombosis in France beyond the 6 first months of treatment, and to prevent cardiovascular events ...
Source: Revue de Medecine Interne - July 19, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Novel Oral Anticoagulant versus Warfarin in Cancer Patients with Atrial Fibrillation: An 8-Year Population-Based Cohort Study
Conclusion: In cancer patients with AF, NOAC were associated with significant reduced IS/SE, major bleeding, and ICH compared to warfarin.
Source: Journal of Cancer - July 2, 2020 Category: Cancer & Oncology Authors: Victor Chien-Chia Wu, Chun-Li Wang, Yu-Tung Huang, Wen-Ching Lan, Michael Wu, Chang-Fu Kuo, Shao-Wei Chen, Pao-Hsien Chu, Ming-Shien Wen, Chi-Ching Kuo, Shang-Hung Chang Tags: Research Paper Source Type: research

Neuroprotective Cationic Arginine-Rich Peptides (CARPs): An Assessment of Their Clinical Safety
AbstractCationic arginine-rich peptides represent a novel class of peptides being developed as neuroprotective agents for stroke and other acute and chronic neurological disorders. As a group, cationic arginine-rich peptides have a diverse range of other biological properties including the ability to traverse cell membranes, modulate immune responses, antagonise ion channel receptor function, as well as possessing cardioprotective, anti-nociceptive, anti-microbial and anti-cancer properties. A sound understanding of their safety profile is essential for the design of future clinical trials and for ensuring translational su...
Source: Drug Safety - June 30, 2020 Category: Drugs & Pharmacology Source Type: research

Ferroptosis: regulated cell death.
Abstract Ferroptosis is a recently identified form of regulated cell death that differs from other known forms of cell death morphologically, biochemically, and genetically. The main properties of ferroptosis are free redox-active iron and consequent iron-dependent peroxidation of polyunsaturated fatty acids in cell membrane phospholipids, which results in the accumulation of lipid-based reactive oxygen species due to loss of glutathione peroxidase 4 activity. Ferroptosis has increasingly been associated with neurodegenerative diseases, carcinogenesis, stroke, intracerebral haemorrhage, traumatic brain injury, and...
Source: Arhiv za Higijenu Rada i Toksikologiju - May 31, 2020 Category: Occupational Health Authors: Čepelak I, Dodig S, Dodig DČ Tags: Arh Hig Rada Toksikol Source Type: research

Weight Change and Mortality from Cardiovascular Diseases: The Japan Collaborative Cohort Study.
CONCLUSIONS: Weight loss or gain could be a risk factor for mortality from total or ischemic CVD, while weight loss could be a risk factor for intracerebral hemorrhage. PMID: 32378530 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - May 8, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Malignant melanoma - the most severe skin cancer and neurological pathology.
CONCLUSIONS: Neurological involvement in MM encompasses a myriad of variants and while the clinical setting varies from one patient to another, an underlining neoplasia should be evaluated in suspected patients. PMID: 32239096 [PubMed - in process]
Source: Romanian Journal of Morphology and Embryology - April 5, 2020 Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research

Carotid Sparing Conformal Radiotherapy for Early Larynx Cancer
Parallel opposed lateral (POL) portals have been adopted as the mainstay radiation therapy technique for early-stage carcinoma of the glottis. Although the use of POL has been associated with excellent control rates and tolerability, the partial inclusion of carotid arteries (CAs) in the high dose regions of the fields has been shown to lead to an increased long-term risk of carotid stenosis and hemorrhagic stroke. Many researchers have proposed the utilization of three-dimension conformal therapy (3DCRT) or Intensity-modulated radiation therapy (IMRT) as viable carotid-sparing techniques via reductions to the mean and max...
Source: International Journal of Radiation Oncology * Biology * Physics - March 12, 2020 Category: Radiology Authors: N.S. Kalman, J. Laher, B. Zholendz Tags: Toxicity, Quality of Life, Survivorship, Costs of Care Source Type: research

Frequency of Seaweed Intake and Its Association with Cardiovascular Disease Mortality: The JACC Study.
CONCLUSIONS: We found an inverse association between seaweed intake and cardiovascular mortality among Japanese men and women, especially that from cerebral infarction. PMID: 32132341 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - March 6, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Long-term Clinical Outcomes of Elective Carotid Artery Stenting in Patients Undergoing Maintenance Hemodialysis.
Conclusion CAS in maintenance hemodialysis patients may be feasible and effective for the prevention of stroke with proper case selection, appropriate technique and strict perioperative management. The most common causes of death during the follow-up of maintenance hemodialysis patients were diseases other than stroke. PMID: 32062623 [PubMed - in process]
Source: Internal Medicine - February 19, 2020 Category: Internal Medicine Tags: Intern Med Source Type: research