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Condition: Hemorrhagic Stroke
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Total 421 results found since Jan 2013.
Multi-disciplinary Approach for Drug and Gene Delivery Systems to the Brain
AAPS PharmSciTech. 2021 Dec 3;23(1):11. doi: 10.1208/s12249-021-02144-1.ABSTRACTDrug delivery into the brain has for long been a huge challenge as the blood-brain barrier (BBB) offers great resistance to entry of foreign substances (with drugs inclusive) into the brain. This barrier in healthy individuals is protective to the brain, disallowing noxious substances present in the blood to get to the brain while allowing for the exchange of small molecules into the brain by diffusion. However, BBB is disrupted under certain disease conditions, such as cerebrovascular diseases including acute ischemic stroke and intracerebral ...
Source: AAPS PharmSciTech - December 4, 2021 Category: Drugs & Pharmacology Authors: Nkafu Bechem Ndemazie Andriana Inkoom Ellis Fualefeh Morfaw Taylor Smith Monica Aghimien Dexter Ebesoh Edward Agyare Source Type: research
How will AI affect radiologist productivity?
Artificial intelligence (AI) software can offer much value in radiology. Bu...Read more on AuntMinnie.comRelated Reading:
Radiologists boost AI severity quantification of COVID-19
Report: Reimbursement drives adoption of AI software for stroke
Can AI help detect cancer on CT lung cancer screening exams?
Can AI help screen for early interstitial lung disease on x-rays?
CT radiomics helps predict spontaneous intracerebral hemorrhage
Source: AuntMinnie.com Headlines - November 18, 2021 Category: Radiology Source Type: news
Disorder Genes Regulate the Progression of Ischemic Stroke through the NF- < em > κ < /em > B Signaling Pathway
Biomed Res Int. 2021 Oct 27;2021:2464269. doi: 10.1155/2021/2464269. eCollection 2021.ABSTRACTStroke is an acute cerebrovascular disease, including ischemic and hemorrhagic stroke. Stroke is the second leading cause of death after ischemic heart disease, which accounts for 9% of the global death toll. To explore the molecular mechanisms of the effects of the dysregulated factors, in the GEO database, we obtained transcriptome data from 24 h/72 h of mice with ischemic stroke and 24 h/72 h of normal mice. We then performed differential gene analysis, coexpression analysis, enrichment analysis, and regulator prediction bioinf...
Source: Biomed Res - November 8, 2021 Category: Research Authors: Wei Wei Wenqiang Xin Yufeng Tang Zhonglun Chen Yue Heng Mingjun Pu Bufan Yang Jiacai Zuo Jingfeng Duan Source Type: research
Janssen to Present the Strength and Promise of its Hematologic Malignancies Portfolio and Pipeline at ASH 2021
RARITAN, N.J., November 4, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 45 company-sponsored abstracts, including 11 oral presentations, plus more than 35 investigator-initiated studies will be featured at the American Society of Hematology (ASH) Annual Meeting and Exposition. ASH is taking place at the Georgia World Congress Center in Atlanta and virtually from December 11-14, 2021.“We are committed to advancing the science and treatment of hematologic malignancies and look forward to presenting the latest research from our robust portfolio and pipeline during ASH...
Source: Johnson and Johnson - November 5, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Is stroke incidence increased in survivors of adult cancers? A systematic review and meta-analysis
ConclusionsStroke incidence is significantly increased after diagnosis of certain cancers.Implications for Cancer SurvivorsCardiovascular risk should be assessed during cancer survivorship care, with attention to modifying shared cancer/cardiovascular risk factors.
Source: Journal of Cancer Survivorship - November 5, 2021 Category: Cancer & Oncology Source Type: research
Post Stroke Hyperglycemia as a marker of Stroke Severity and Prognosis: A cohort study
ConclusionFrom our study we can conclude that diabetes mellitus as a risk factor in cases of stroke leads to increase complications and worsens the outcome in cases of stroke whether hemorrhagic or ischemic.RecommendationsFrom our study we recommended strict control of diabetes mellitus when present in cases of stroke to avoid bad outcome and to prevent complications in these cases.
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Development of Biomembrane-mimetic Nanoparticles for the Treatment of Ischemic Stroke
Yakugaku Zasshi. 2021;141(9):1071-1078. doi: 10.1248/yakushi.21-00114.ABSTRACTIncrease in vascular permeability of the blood-brain barrier (BBB) is a distinct pathology following ischemic stroke. In previous studies, we demonstrated that liposomal drug delivery system (DDS)-based delivery of neuroprotectants is useful for treating cerebral ischemia/reperfusion injury. Additionally, our previous studies reported that combination therapy with liposomal fasudil plus tissue plasminogen activator (t-PA), a thrombolytic agent, brings about decrease in the risk of t-PA-derived cerebral hemorrhage and prolong the therapeutic time ...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - September 2, 2021 Category: Drugs & Pharmacology Authors: Tatsuya Fukuta Source Type: research
