Perfluorooctanoic acid affects mouse brain and liver tissue through oxidative stress
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):148-157. doi: 10.2478/aiht-2022-73-3629.ABSTRACTThe aim of this study was to investigate oxidative stress induced by perfluorooctanoic acid (PFOA) in the brain and liver tissues of Balb/c mice as well as protective effects of taurine and coenzyme Q10 (CoQ10) in both organs. For this purpose, animals were treated with PFOA (15 and 30 mg/kg) orally and their lipid peroxidation, total glutathione levels (GSH), and antioxidant enzyme activities measured and both tissues analysed for histopathological changes. Our results showed a dose-dependent decrease in body weight and increase in rel...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Burcu Ünlü Endirlik Ay şe Eken Hande Canp ınar Figen Öztürk Aylin G ürbay Source Type: research

Joint impact of key air pollutants on COVID-19 severity: prediction based on toxicogenomic data analysis
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):119-125. doi: 10.2478/aiht-2022-73-3631.ABSTRACTConsidering that some researchers point to a possible influence of air pollution on COVID-19 transmission, severity, and death rate, the aim of our in silico study was to determine the relationship between the key air pollutants [sulphur dioxide (SO), carbon monoxide (CO), 2particulate matter (PMx), nitrogen dioxide (NO2), and ozone (O3)] and COVID-19 complications using the publicly available toxicogenomic analytical and prediction tools: (i) Comparative Toxicogenomic Database (CTD) to identify genes common to air pollutants and COVID-...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Danijela Đukić-Ćosić Katarina Barali ć Teodora Filipovi ć Dragica Bo žić Katarina Živančević Evica Antonijevi ć Miljaković Aleksandra Buha Đorđević Zorica Bulat Biljana Antonijevi ć Marijana Ćurčić Source Type: research

Fish consumption habits of pregnant women in Itaituba, Tapaj ós River basin, Brazil: risks of mercury contamination as assessed by measuring total mercury in highly consumed piscivore fish species and in hair of pregnant women
In this study, we evaluated fish consumption habits and mercury exposure in 110 pregnant women in the city of Itaituba by measuring their total hair mercury concentrations. In addition, we investigated seasonal differences in mercury concentrations in two highly consumed piscivorous fish species, tucunaré (Cichla spp.) and pescada (Plagioscion squamosissimus). Total fish mercury concentrations (THg) during the dry season were 0.62±0.07 mg/kg for Cichla spp. and 0.73±0.08 mg/kg for P. squamosissimus. During the rainy season they were 0.39±0.04 and 0.84±0.08 mg/ kg, respectively. Of our participants 44 % declared that t...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Ricardo Bezerra de Oliveira Domingas Machado da Silva Thamilles Santa B árbara Sousa Franco Cl áudio Ramon Sena Vasconcelos Deise Juliane Dos Anjos de Sousa Sandra Layse Ferreira Sarrazin Mineshi Sakamoto Jean-Paul Bourdineaud Source Type: research

Antioxidative, cytotoxic, and antibacterial properties of self-assembled glycine-histidine-based dipeptides with or without silver nanoparticles in bio-inspired film
In this study we investigated the effects of varying solvent environments on the self-assembly of glycine-histidine (Gly-His) dipeptide structures. First we determined the morphological properties of Gly-His films formed in different solvent environments with scanning electron microscopy and then structural properties with Fourier-transform infrared (FTIR) spectroscopy. In addition, we studied the effects of Gly-His films on silver nanoparticle (AgNP) formation and the antioxidant and cytotoxic properties of AgNPs obtained in this way. We also, assessed antibacterial activities of Gly-His films against Gram-negative Escher...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Merve Eylul Kiymaci Hakan Erdo ğan Merve Bacanl ı Source Type: research

Cytotoxic activity of strawberry tree ( < em > Arbutus unedo < /em > L.) honey, its extract, and homogentisic acid on CAL 27, HepG2, and Caco-2 cell lines
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):158-168. doi: 10.2478/aiht-2022-73-3653.ABSTRACTStrawberry tree (Arbutus unedo L.) honey (STH), also known as "bitter honey", is a traditional medicine widely used in the Mediterranean area. Regardless of geographical origin, it usually has a very high content of phenolic compounds and strong antioxidant capacity. Yet, little is still known about the effects of STH, its phenolic extract (STHE), and its main bioactive compound - homogentisic acid (HGA) - at the cell level. The aim of this study was to estimate total phenolic content, DPPH radical scavenging activity, and ferric reduci...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Andreja Juri č Ana Hu đek Turković Irena Br čić Karačonji Sa ša Prđun Dragan Bubalo Ksenija Durgo Source Type: research

COVID-19 infection masquerading as recurrent apnoea in acute opioid overdose
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):178. doi: 10.2478/aiht-2022-73-3661.NO ABSTRACTPMID:35792770 | PMC:PMC9287830 | DOI:10.2478/aiht-2022-73-3661 (Source: Arhiv za Higijenu Rada i Toksikologiju)
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Seyed Mostafa Mirakbari Source Type: research

Validity, internal consistency, and test-retest reliability of the Montenegrin 10-item Voice Handicap Index
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):143-147. doi: 10.2478/aiht-2022-73-3624.ABSTRACTThe purpose of the this cross-sectional study was to assess clinical validity, internal consistency, and test-retest reliability of the adapted Montenegrin translation of the Voice Handicap Index 10 (VHI-10). It included 50 patients with voice disorders, divided into three subgroups according disease aetiology: structural, neurological, and functional and a control group of 50 vocally healthy participants. Mean patient VHI-10 score of 21.1±7.6 was significantly higher than the 2.3±2.5 score of controls (p<0.001). Each of the three ...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Elvir Zvrko Muhedin Kadi ć Source Type: research

Wi-Fi technology and human health impact: a brief review of current knowledge
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):94-106. doi: 10.2478/aiht-2022-73-3402.ABSTRACTAn enormous increase in the application of wireless communication in recent decades has intensified research into consequent increase in human exposure to electromagnetic (EM) radiofrequency (RF) radiation fields and potential health effects, especially in school children and teenagers, and this paper gives a snap overview of current findings and recommendations of international expert bodies, with the emphasis on exposure from Wi-Fi technology indoor devices. Our analysis includes over 100 in vitro, animal, epidemiological, and exposure...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Ivica Prli ć Jerko Šiško Veda Marija Varnai Luka Paveli ć Jelena Macan Silvija Kobe šćak Mladen Hajdinjak Mihovil Jurdana Zdravko Cerovac Branimir Zauner Marija Suri ć Mihić Selma Cvijeti ć Avdagić Source Type: research

Olanzapine poisoning in patients treated at the National Poison Control Centre in Belgrade, Serbia in 2017 and 2018: a brief review of serum concentrations and clinical symptoms
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):126-130. doi: 10.2478/aiht-2022-73-3635.ABSTRACTOlanzapine is a thienobenzodiazepine class antipsychotic that strongly antagonises the 5-HT2A serotonin receptor, but acute poisonings are reported rarely. Symptoms of an overdose include disorder of consciousness, hypersalivation, myosis, and coma. Serum concentration higher than 0.1 mg/L is toxic, while concentration above 1 mg/L can be fatal. Here we report key data about 61 patients admitted to the National Poison Control Centre in Belgrade, Serbia over olanzapine poisoning in 2017 and 2018. The ingested doses ranged from 35 to 1680...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Sne žana Đorđević Nata ša Perković Vukčević Marko Antunovi ć Vesna Kilibarda Gordana Vukovi ć Ercegović Jasmina Jovi ć Stošić Slavica Vu činić Source Type: research

Occupational exposure to BTEX and styrene in West Asian countries: a brief review of current state and limits
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):107-118. doi: 10.2478/aiht-2022-73-3634.ABSTRACTThe aim of introducing occupational exposure limits (OELs) is to use them as a risk management tool in order to protect workers' health and well-being against harmful agents at the workplace. In this review we identify OELs for benzene, toluene, ethylbenzene, xylene (BTEX), and styrene concentrations in air and assess occupational exposure to these compounds through a systematic literature search of publications published in West Asian countries from 1980 to 2021. OELs for BTEX and styrene have been set in Iran and Turkey to levels simi...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Razzagh Rahimpoor Fatemeh Sarvi Samira Rahimnejad Seyed Mohammad Ebrahimi Source Type: research

Perfluorooctanoic acid affects mouse brain and liver tissue through oxidative stress
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):148-157. doi: 10.2478/aiht-2022-73-3629.ABSTRACTThe aim of this study was to investigate oxidative stress induced by perfluorooctanoic acid (PFOA) in the brain and liver tissues of Balb/c mice as well as protective effects of taurine and coenzyme Q10 (CoQ10) in both organs. For this purpose, animals were treated with PFOA (15 and 30 mg/kg) orally and their lipid peroxidation, total glutathione levels (GSH), and antioxidant enzyme activities measured and both tissues analysed for histopathological changes. Our results showed a dose-dependent decrease in body weight and increase in rel...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Burcu Ünlü Endirlik Ay şe Eken Hande Canp ınar Figen Öztürk Aylin G ürbay Source Type: research

Joint impact of key air pollutants on COVID-19 severity: prediction based on toxicogenomic data analysis
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):119-125. doi: 10.2478/aiht-2022-73-3631.ABSTRACTConsidering that some researchers point to a possible influence of air pollution on COVID-19 transmission, severity, and death rate, the aim of our in silico study was to determine the relationship between the key air pollutants [sulphur dioxide (SO), carbon monoxide (CO), 2particulate matter (PMx), nitrogen dioxide (NO2), and ozone (O3)] and COVID-19 complications using the publicly available toxicogenomic analytical and prediction tools: (i) Comparative Toxicogenomic Database (CTD) to identify genes common to air pollutants and COVID-...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Danijela Đukić-Ćosić Katarina Barali ć Teodora Filipovi ć Dragica Bo žić Katarina Živančević Evica Antonijevi ć Miljaković Aleksandra Buha Đorđević Zorica Bulat Biljana Antonijevi ć Marijana Ćurčić Source Type: research

Fish consumption habits of pregnant women in Itaituba, Tapaj ós River basin, Brazil: risks of mercury contamination as assessed by measuring total mercury in highly consumed piscivore fish species and in hair of pregnant women
In this study, we evaluated fish consumption habits and mercury exposure in 110 pregnant women in the city of Itaituba by measuring their total hair mercury concentrations. In addition, we investigated seasonal differences in mercury concentrations in two highly consumed piscivorous fish species, tucunaré (Cichla spp.) and pescada (Plagioscion squamosissimus). Total fish mercury concentrations (THg) during the dry season were 0.62±0.07 mg/kg for Cichla spp. and 0.73±0.08 mg/kg for P. squamosissimus. During the rainy season they were 0.39±0.04 and 0.84±0.08 mg/ kg, respectively. Of our participants 44 % declared that t...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Ricardo Bezerra de Oliveira Domingas Machado da Silva Thamilles Santa B árbara Sousa Franco Cl áudio Ramon Sena Vasconcelos Deise Juliane Dos Anjos de Sousa Sandra Layse Ferreira Sarrazin Mineshi Sakamoto Jean-Paul Bourdineaud Source Type: research

Antioxidative, cytotoxic, and antibacterial properties of self-assembled glycine-histidine-based dipeptides with or without silver nanoparticles in bio-inspired film
In this study we investigated the effects of varying solvent environments on the self-assembly of glycine-histidine (Gly-His) dipeptide structures. First we determined the morphological properties of Gly-His films formed in different solvent environments with scanning electron microscopy and then structural properties with Fourier-transform infrared (FTIR) spectroscopy. In addition, we studied the effects of Gly-His films on silver nanoparticle (AgNP) formation and the antioxidant and cytotoxic properties of AgNPs obtained in this way. We also, assessed antibacterial activities of Gly-His films against Gram-negative Escher...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Merve Eylul Kiymaci Hakan Erdo ğan Merve Bacanl ı Source Type: research

Cytotoxic activity of strawberry tree ( < em > Arbutus unedo < /em > L.) honey, its extract, and homogentisic acid on CAL 27, HepG2, and Caco-2 cell lines
Arh Hig Rada Toksikol. 2022 Jul 7;73(2):158-168. doi: 10.2478/aiht-2022-73-3653.ABSTRACTStrawberry tree (Arbutus unedo L.) honey (STH), also known as "bitter honey", is a traditional medicine widely used in the Mediterranean area. Regardless of geographical origin, it usually has a very high content of phenolic compounds and strong antioxidant capacity. Yet, little is still known about the effects of STH, its phenolic extract (STHE), and its main bioactive compound - homogentisic acid (HGA) - at the cell level. The aim of this study was to estimate total phenolic content, DPPH radical scavenging activity, and ferric reduci...
Source: Arhiv za Higijenu Rada i Toksikologiju - July 6, 2022 Category: Occupational Health Authors: Andreja Juri č Ana Hu đek Turković Irena Br čić Karačonji Sa ša Prđun Dragan Bubalo Ksenija Durgo Source Type: research