Filtered By:
Cancer: Colorectal Cancer
This page shows you your search results in order of date. This is page number 3.
Order by Relevance | Date
Total 1289 results found since Jan 2013.
Exosomes-delivered PD-L1 siRNA and CTLA-4 siRNA protect against growth and tumor immune escape in colorectal cancer
CONCLUSION: Exosomes containing PD-L1 siRNA and CTLA-4 siRNA suppressed CRC progression and enhanced tumor immune responses.PMID:37217085 | DOI:10.1016/j.ygeno.2023.110646
Source: Genomics - May 22, 2023 Category: Genetics & Stem Cells Authors: Jian Li Yuxiang Chen Mingmei Liao Shuyi Yu Binwen Yuan Zeming Jia Lin Zhou Yaping Tang Source Type: research
NKD1 promotes glucose uptake in colon cancer cells by activating YWHAE transcription
CONCLUSION: NKD1 protein activates the transcriptional activity of YWHAE gene to promote glucose uptake in colon cancer cells.PMID:37202194 | PMC:PMC10202780 | DOI:10.12122/j.issn.1673-4254.2023.04.11
Source: Journal of Southern Medical University - May 18, 2023 Category: Universities & Medical Training Authors: Q Liu Y Dai H Yu Y Shen J Deng W Lu J Jin Source Type: research
Targeted and Functional Genomics Approaches to the Mechanism of Action of Lagunamide D, a Mitochondrial Cytotoxin from Marine Cyanobacteria
Biochem Pharmacol. 2023 May 16:115608. doi: 10.1016/j.bcp.2023.115608. Online ahead of print.ABSTRACTLagunamide D, a cyanobacterial cyclodepsipeptide, exhibits potent antiproliferative activity against HCT116 colorectal cancer cells (IC50 5.1 nM), used as a model system to probe the mechanism of action. Measurements of metabolic activity, mitochondrial membrane potential, caspase 3/7 activity and cell viability indicate the rapid action of lagunamide D on mitochondrial function and downstream cytotoxic effects in HCT116 cells. Lagunamide D preferentially targets the G1 cell cycle population and arrests cells in G2/M phase ...
Source: Biochemical Pharmacology - May 18, 2023 Category: Drugs & Pharmacology Authors: Danmeng Luo Ranjala Ratnayake Kalina R Atanasova Valerie J Paul Hendrik Luesch Source Type: research
NKD1 promotes glucose uptake in colon cancer cells by activating YWHAE transcription
CONCLUSION: NKD1 protein activates the transcriptional activity of YWHAE gene to promote glucose uptake in colon cancer cells.PMID:37202194 | PMC:PMC10202780 | DOI:10.12122/j.issn.1673-4254.2023.04.11
Source: Journal of Southern Medical University - May 18, 2023 Category: Universities & Medical Training Authors: Q Liu Y Dai H Yu Y Shen J Deng W Lu J Jin Source Type: research
Targeted and Functional Genomics Approaches to the Mechanism of Action of Lagunamide D, a Mitochondrial Cytotoxin from Marine Cyanobacteria
Biochem Pharmacol. 2023 May 16:115608. doi: 10.1016/j.bcp.2023.115608. Online ahead of print.ABSTRACTLagunamide D, a cyanobacterial cyclodepsipeptide, exhibits potent antiproliferative activity against HCT116 colorectal cancer cells (IC50 5.1 nM), used as a model system to probe the mechanism of action. Measurements of metabolic activity, mitochondrial membrane potential, caspase 3/7 activity and cell viability indicate the rapid action of lagunamide D on mitochondrial function and downstream cytotoxic effects in HCT116 cells. Lagunamide D preferentially targets the G1 cell cycle population and arrests cells in G2/M phase ...
Source: Biochemical Pharmacology - May 18, 2023 Category: Drugs & Pharmacology Authors: Danmeng Luo Ranjala Ratnayake Kalina R Atanasova Valerie J Paul Hendrik Luesch Source Type: research
NKD1 promotes glucose uptake in colon cancer cells by activating YWHAE transcription
CONCLUSION: NKD1 protein activates the transcriptional activity of YWHAE gene to promote glucose uptake in colon cancer cells.PMID:37202194 | DOI:10.12122/j.issn.1673-4254.2023.04.11
Source: Journal of Southern Medical University - May 18, 2023 Category: Universities & Medical Training Authors: Q Liu Y Dai H Yu Y Shen J Deng W Lu J Jin Source Type: research
