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ZNF574 Promotes Ovarian Cancer Cell Proliferation and Migration through Regulating AKT and AMPK Signaling Pathways
CONCLUSION: These results indicated that ZNF574 may function as an oncogene in ovarian cancer through regulation of the AKT and AMPK signaling pathways. Furthermore, ZNF574 may be a prognostic indicator and therapeutic target for ovarian cancer.PMID:36197766
Source: Annals of Clinical and Laboratory Science - October 5, 2022 Category: Laboratory Medicine Authors: Jingjing Zhang Xiaoli Wu Li Huang Source Type: research
The effect of neuropilin-1 silencing on the transforming growth factor- β1-mediated epithelial-mesenchymal transition of colon cancer SW480 cells and its effect on the proliferation and migration of colon cancer cells
In conclusion: silencing, NRP-1 in colon cancer SW480 cells can partially reverse TGF-β1-mediated EMT, reduce the proliferation activity of colon cancer cells, and slow their migration ability. Therefore, NRP-1 may become a new target for the treatment of colon cancer.PMID:36193963 | DOI:10.26402/jpp.2022.2.07
Source: Journal of Physiology and Pharmacology - October 4, 2022 Category: Drugs & Pharmacology Authors: B Zhu Q-Q Zhan Q-Y Liu X Yang Y-H Ge G-Y Ding S Guo W-G Xu Source Type: research
