Filtered By:
Cancer: Colorectal Cancer
This page shows you your search results in order of date. This is page number 12.
Order by Relevance | Date
Total 1289 results found since Jan 2013.
Targeting K-Ras Mutations Show Promise Towards Ending Ras's "Undruggable" Era
Protein Pept Lett. 2022 Oct 3. doi: 10.2174/0929866529666221003124202. Online ahead of print.ABSTRACTIt has almost been 40 years since the Ras proteins were discovered as the first human oncogenes. They remain among the most important genes for regulating mammalian cell growth and are involved in more than a quarter of human cancers. Out of 167 members of the Ras superfamily, K-Ras mutations are the most abundant in human cancers. Particularly, the K-Ras G12C mutations are known to be involved in pancreatic, colon and lung cancers as well as leukemias. Though progress has been made, approaches that target Ras proteins for ...
Source: Protein and Peptide Letters - October 6, 2022 Category: Biochemistry Authors: Paul D Adams D Jamali Muhoza Source Type: research
ZNF574 Promotes Ovarian Cancer Cell Proliferation and Migration through Regulating AKT and AMPK Signaling Pathways
CONCLUSION: These results indicated that ZNF574 may function as an oncogene in ovarian cancer through regulation of the AKT and AMPK signaling pathways. Furthermore, ZNF574 may be a prognostic indicator and therapeutic target for ovarian cancer.PMID:36197766
Source: Annals of Clinical and Laboratory Science - October 5, 2022 Category: Laboratory Medicine Authors: Jingjing Zhang Xiaoli Wu Li Huang Source Type: research
