Resveratrol regulates Nrf2-mediated expression of antioxidant and xenobiotic metabolizing enzymes in pesticides-induced Parkinsonism.
CONCLUSION: The results suggest that resveratrol promotes the catalytic activity of xenobiotic metabolizing enzyme, Cyp2d22/CYP2D6, which partially contributes to Nrf2 activation in pesticides-induced Parkinsonism. PMID: 32242774 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - April 3, 2020 Category: Biochemistry Authors: Sami-Ur-Rasheed M, Tripathi MK, Patel DK, Singh MP Tags: Protein Pept Lett Source Type: research

Bovine lactoferrin can decrease the in vitro biofilm production or shown synergy with antibiotics against Listeria and Escherichia coli isolates.
CONCLUSION: bLf can affect the biofilm production in Listeria isolates from slaughterhouses surfaces and shown synergic effect with ampicillin. Also has a synergic effect with oxytetracycline and streptomycin against E. coli isolates from bovine carcasses. PMID: 32242775 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - April 3, 2020 Category: Biochemistry Authors: Alejandra GK, Ivonne CO, Sarahí LC, Yosahandy PA Tags: Protein Pept Lett Source Type: research

Denaturant induced equilibrium unfolding and conformational transitional studies of germinated fenugreek β-amylase revealed molten globule like state at low pH.
CONCLUSION: Results indicate the probable existence of intermediate states that might perform significant role in physiological process and biotechnological applications. PMID: 32242773 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - April 2, 2020 Category: Biochemistry Authors: Agrawal DC, Yadav A, Khan MA, Kundu S, Kayastha AM Tags: Protein Pept Lett Source Type: research

Expression of brazzein, a small sweet-tasting protein in Saccharomyces cerevisiae: an introduction for production of sweet yeasts.
CONCLUSION: Although the yield of GST-Braz was higher than His-Braz and Braz expressed in S. cerevisiae, but the higher solubility, sweetness, safety (GRAS) are important advantages of the use of S. cerevisiae as expression host for production of Braz. Therefore the result of present work opens new insights for providing the new sweet yeasts that can be used as food additives. PMID: 32228415 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - March 31, 2020 Category: Biochemistry Authors: Shahpiri A, Kazemi-Nasab A Tags: Protein Pept Lett Source Type: research

Diosmetin Induces Apoptosis by Downregulating AKT Phosphorylation via P53 Activation in Human Renal Carcinoma ACHN Cells.
CONCLUSION: Our data suggested that DIOS induced apoptosis in renal carcinoma ACHN cells by reducing AKT phosphorylation through p53 upregulation. PMID: 32223728 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - March 30, 2020 Category: Biochemistry Authors: Qiu M, Liu J, Su Y, Guo R, Zhao B, Liu J Tags: Protein Pept Lett Source Type: research

Computational Method in Protein Structure and Function Data.
PMID: 32207398 [PubMed - in process] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - March 26, 2020 Category: Biochemistry Authors: Lin H Tags: Protein Pept Lett Source Type: research

A Novel Amino Acid Properties Selection Method for Protein Fold Classification.
CONCLUSION: The proposed properties selection method can be extended to other biomolecule property related classification problems in bioinformatics. PMID: 32207399 [PubMed - in process] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - March 26, 2020 Category: Biochemistry Authors: Zhang L, Kong L Tags: Protein Pept Lett Source Type: research

Aloperine Induces Apoptosis by a Reactive Oxygen Species Activation Mechanism in Human Ovarian Cancer Cells.
CONCLUSION: Taken together, our results indicated that aloperine could exert anti-ovarian cancer cell activity through a reactive oxygen species activation mechanism and suggested aloperine as a potential agent against ovarian cancer. PMID: 32196436 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - March 19, 2020 Category: Biochemistry Authors: Qiu M, Liu J, Su Y, Liu J, Wu C, Zhao B Tags: Protein Pept Lett Source Type: research

Establishment and in vitro evaluation of porous ion-responsive targeted drug delivery system.
CONCLUSION: In this paper, CBCCPM, a porous ion-responsive targeted drug delivery system, was designed. PMID: 32196437 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - March 19, 2020 Category: Biochemistry Authors: Liu H, Zhu J, Bao P, Ding Y, Wang J, Du Y, Qu Y, Xu Y Tags: Protein Pept Lett Source Type: research

Parakeet hemoglobin - its crystal structure and oxygen affinity in relation to some avian hemoglobins.
Conclusion The present study describes the structure determination of parakeet hemoglobin and its structural features to understand its oxygen affinity characteristics. The crystals were obtained by buffered low-salt conditions, like those of chicken HbD, carbonmonoxy and cyanomet human Hb. The present study reveals several interesting and unique modifications in the finer aspects of the quaternary structure of parakeet Hb, which are involved in oxygen affinity characteristics and the α1β1 subunit contacts. Crystallization of parakeet Hb with allosteric effectors like Inositol pentaphosphate may bring further un...
Source: Protein and Peptide Letters - March 19, 2020 Category: Biochemistry Authors: Jaimohan Sm, Naresh Md, Mandal A B Tags: Protein Pept Lett Source Type: research

The influence of Ca2+ and Zn2+ on the amyloid fibril formation by β-casein.
CONCLUSION: Ca2+ and Zn2+ were capable of promoting the β-casein fibril formation in the both absence and presence of HS. This work set up the foundation for further researching of the amyloidosis pathogenesis and provided new insight for us to understand relationship between the inflammation and amyloidosis. PMID: 32186269 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - March 18, 2020 Category: Biochemistry Authors: Liu J, Wang J, Du G, An Y, Zhao C, Zeng B Tags: Protein Pept Lett Source Type: research

Using a heat diffusion model to detect potential drug resistance genes of Mycobacterium tuberculosis.
Abstract BACKGROUND: Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is one of the oldest known and most dangerous diseases. Although the spread of TB was controlled in the early 20th century using antibiotics and vaccines, TB has again become a threat because of increased drug resistance. There is still a lack of effective treatment regimens for a person who is already infected with multidrug-resistant Mtb (MDR-Mtb) or extensively drug-resistant Mtb (XDR-Mtb). In the past decades, many research groups have explored the drug resistance profiles of Mtb based on sequence data by GWAS, which identified...
Source: Protein and Peptide Letters - March 13, 2020 Category: Biochemistry Authors: Cui ZJ, Zhang WT, Zhu Q, Zhang QY, Zhang HY Tags: Protein Pept Lett Source Type: research

Non-Enzymatic Protein Acetylation by 7-acetoxy-4-methylcoumarin: Implications in Protein Biochemistry.
CONCLUSION: Thus protein acetylation induced by 7-AMC could also be non-enzymatic in nature and this molecule can be exploited for quantification of proteins. PMID: 32133945 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - March 5, 2020 Category: Biochemistry Authors: Bhatt AN, Rai Y, Verma A, Pandey S, Kaushik K, Parmar VS, Arya A, Prasad AK, Dwarakanath BS Tags: Protein Pept Lett Source Type: research

Lithium-Protein Interactions: Analysis of Lithium-Containing Protein Crystal Structures deposited in the Protein Data Bank.
Conclusion: Although structural information on lithium-protein, available from the Protein Data Bank, is relatively scarce, these trends appears to be so clear that one may suppose that they will be confirmed by further data that will join the Protein Data Bank in the future. PMID: 32133946 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - March 5, 2020 Category: Biochemistry Authors: Carugo O Tags: Protein Pept Lett Source Type: research

A Study On Serological Reactivity Profile Of Different Antigen Preparations With Bancroftian Filariasis Human Infection Sera.
CONCLUSION: In the present study, we endeavoured to establish the extent of cross-reactivity of antigens derived from animal filarial parasites such as B. malayi and S. cervi with W. bancrofti filariasis sera of human patients. Besides, we further analyzed antibody-isotype profile of IgG, IgG4 and IgM in various human infection sera of bancroftian filarial subjects reactive to heterologous parasite antigens derived from adult worms of S. cervi from bovine and B. malayi. PMID: 32096736 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - February 25, 2020 Category: Biochemistry Authors: Saeed M, Kushvaha V, Faisal SM, Verma R, Ahmad I, Mustafa H, Ganash M, Kamal MA, Ashraf GM Tags: Protein Pept Lett Source Type: research

Identification of Salmonella Typhimurium Peptidyl-prolyl cis-trans isomerase B (PPIase B) and assessment of their role in the protein folding.
CONCLUSION: Taken together, our data clearly showed that Salmonella Cyclophilin B (PpiB) protein is active and involved in diverse biological processes and highly similar to the different domain of Cyclophilin proteins. PMID: 32096737 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - February 25, 2020 Category: Biochemistry Authors: Kumawat M, Karuna I, Ahlawat N, Ahlawat S Tags: Protein Pept Lett Source Type: research

Combination of copper ions and nucleotide generates aggregates from prion protein fragments in the N-terminal domain.
CONCLUSION: The phosphate group on the adenine-linked ribose moiety of adenine nucleotides and pyridine nucleotides is presumed to be essential for the observed effect on aggregation. Efficient aggregation requires the presence of the four octarepeats. These insights may be helpful in the eventual development of therapeutic agents against prion-related disorders. PMID: 32096738 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - February 25, 2020 Category: Biochemistry Authors: Shiraishi N, Hirano Y Tags: Protein Pept Lett Source Type: research

Directive effect of chain length in modulating peptide nano-assemblies.
Abstract RADA-4 (Ac-RADARADARADARADA-NH2) is the most extensively studied and marketed self- assembling peptide, forming hydrogel, used to create defined three-dimensional microenvironments for cell culture applications. In this work, we use various biophysical techniques to investigate the length dependency of RADA aggregation and assembly. We synthesized a series of RADA-N peptides, N ranging from 1 to 4, resulting in four peptides having 4, 8, 12, and 16 amino acids in their sequence. Our observations show that the aggregation of ionic, charge-complementary RADA motif-containing peptides is length-dependent, wi...
Source: Protein and Peptide Letters - February 23, 2020 Category: Biochemistry Authors: Pandey G, Das PP, Ramakrishnan V Tags: Protein Pept Lett Source Type: research

EGLLGDVF: a novel peptide from green mussel Perna viridis foot exerts stability and anti-inflammatory effects on LPS - stimulated RAW264.7 cells.
CONCLUSION: Our study indicates that EGLLGDVF derived from PVF has potential anti-inflammatory applications applicable in food and pharmaceutical industries. PMID: 32091325 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - February 23, 2020 Category: Biochemistry Authors: Joshi I, Nazeer RA Tags: Protein Pept Lett Source Type: research

In silico and In vitro investigation of a likely pathway for anti-cancerous effect of Thrombocidin-1 as a novel anticancer peptide.
CONCLUSION: Therefore, apart from probable anti-cancerous effect of rTC-1 on C26-A and SW1353 cell lines, this peptide may be able to mimic the anti-cancerous pathway of IL-8. PMID: 32072885 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - February 18, 2020 Category: Biochemistry Authors: Tanhaian A, Mohammadi E, Vakili-Ghartavol R, Saberi MR, Mirzayi M, Jaafari MR Tags: Protein Pept Lett Source Type: research

Self-assembly of cyclic dipeptides: platforms for functional materials.
Abstract Supramolecular self-assembled functional materials comprised of cyclic dipeptide building blocks have excellent prospects for biotechnology applications due to their exceptional structural rigidity, morphological flexibility, ease of preparation and modification. Although the pharmacological uses of many natural cyclic dipeptides have been studied in detail, relatively little is reported on the engineering of these supramolecular architectures for the fabrication of functional materials. In this review, we discuss the progress in the design, synthesis, and characterization of cyclic dipeptide supramolecul...
Source: Protein and Peptide Letters - February 12, 2020 Category: Biochemistry Authors: Chen Y, Tao K, Ji W, Makam P, Rencus-Lazar S, Gazit E Tags: Protein Pept Lett Source Type: research

Cross-talk of Signaling Pathways in the Pathogenesis of Allergic Asthma and Cataract.
Abstract Allergic asthma is a chronic inflammatory disease, which involves many cellular and cellular components. Cataract is a condition that affects the transparency of the lens, which the opacity of the lens caused by any innate or acquired factor degrades its transparency or changes in color. Both of them belong to diseases induced by immune disorders or inflammation. We want to confirm the signaling pathways involved in the regulation of asthma and cataract simultaneously, and provide reference for the later related experiments. So we conducted a scoping review of many databases and searched for studies (Acad...
Source: Protein and Peptide Letters - February 6, 2020 Category: Biochemistry Authors: Zhao Y, Liu S, Li X, Xu Z, Hao L, Cui Z, Bi K, Zhang Y, Liu Z Tags: Protein Pept Lett Source Type: research

Stepwise development of biomimetic chimeric peptides for gene delivery.
Abstract Gene-based therapy largely relies on the vector type that allows a selective and efficient transfection into the target cells with maximum efficacy and minimal toxicity. Although, genes delivered utilizing modified viruses transfect efficiently and precisely, these vectors can cause severe immunological responses and are potentially carcinogenic. A promising method of overcoming this limitation is the use of non-viral vectors, including cationic lipids, polymers, dendrimers, and peptides, which offer potential routes for compacting DNA for targeted delivery. Although non-viral vectors exhibit reduced tran...
Source: Protein and Peptide Letters - February 6, 2020 Category: Biochemistry Authors: Cheraghi R, Nazari M, Alipour M, Hosseinkhani S Tags: Protein Pept Lett Source Type: research

Studies on molecular interactions between bovine β-lactoglobulin and silver nanoparticles.
Studies on molecular interactions between bovine β-lactoglobulin and silver nanoparticles. Protein Pept Lett. 2020 Jan 29;: Authors: Sharma A, Ghosh KS Abstract Interactions between bovine β-lactoglobulin (BLG) and silver nanoparticles (AgNPs) were studied at four different temperatures based on the Trp fluorescence quenching of BLG by AgNPs. Protein-nanoparticles association constant was in the range of 106-1010 M-1 and the quenching constant was determined as ~107 M-1. Ground state complexation between the protein and nanoparticles was predicted. Changes in polarity surrounding the Trp res...
Source: Protein and Peptide Letters - January 29, 2020 Category: Biochemistry Authors: Sharma A, Ghosh KS Tags: Protein Pept Lett Source Type: research

Structural Plasticity of EAK-16 Peptide Inducing Vesicle Membrane Leakage.
CONCLUSION: This study demonstrated the supporting evidence that EAK-16 could interact with lipid membranes and conforming to helical structure, while the helical conformation induced the lipid membrane leakage. Overall, this study provides a physical rationale that ionic complementary peptide can be a useful tool for designing and development of novel antibiotics and anticancer agents along its previous drug delivery applications. PMID: 32003653 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - January 29, 2020 Category: Biochemistry Authors: Majid A, Naz F, Khaskheli MH Tags: Protein Pept Lett Source Type: research

Effect of Isolated Proteins from Crotalus Durissus Terrificus Venom on Leishmania (Leishmania) Amazonensis-Infected Macrophages.
CONCLUSION: The Crotalus durissus terrificus toxins used in this study displayed significant activity against L. (L.) amazonensis, indicating that all of them could be a potential alternative for the treatment of cutaneous leishmaniasis. PMID: 31994997 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - January 29, 2020 Category: Biochemistry Authors: Katz S, Barbiéri CL, Soler FPM, Soares AM, Chavantes MC, Zamuner SR Tags: Protein Pept Lett Source Type: research

Characterization of Three Osmotin-Like Proteins from Plumeria rubra and Prospection for Adiponectin Peptidomimetics.
CONCLUSION: As observed for tobacco osmotin, the latex osmotins of P. rubra exhibited compatible interactions with adiponectin receptors. Therefore, these plant defense proteins (without known counterparts in humans) are potential tools to study modulation of glucose metabolism in type II diabetes, where adiponectin plays a pivotal role in homeostasis. PMID: 31994998 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - January 29, 2020 Category: Biochemistry Authors: Freitas CDT, Nishi BC, do Nascimento CTM, Silva MZR, Bezerra EHS, Rocha BAM, Grangeiro TB, Oliveira JPB, Souza PFN, Ramos MV Tags: Protein Pept Lett Source Type: research

Purification and Characterization of a Novel Rhamnose/Fucose-Specific Lectin from the Hemolymph of Oak Tasar (Antheraea proylei J.) Silkworm.
CONCLUSION: A novel rhamnose/fucose-specific lectin was purified to electrophoretic homogeneity from hemolymph of oak tasar (Antheraea proylei J.) silkworm. The lectin was found to be a monomeric protein with a native molecular weight of 39.5 kDa. Its activity was found to be independent of metal ion, optimum at pH 7-7.5 and characterized by thermal stability with t1/2 of 60°C. Analysis with tandem mass spectrometry coupled with Mascot sequence matching software confirmed the purified lectin to be a protein not characterized earlier. PMID: 31994999 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - January 29, 2020 Category: Biochemistry Authors: Devi HK, Devi SK, Rully H, Singh SJ, Singh WS, Thongam H, Singh LR Tags: Protein Pept Lett Source Type: research

Renin-angiotensin-aldosterone system and migraine: a systematic review of human studies.
Abstract Migraine is a common neurologic condition marked by recurrent episodes of headache. Its pathophysiology is highly complex involving neuronal, inflammatory and vascular mechanisms. The Renin-Angiotensin System (RAS) can modulate all these mechanism, being a potential pharmacological target for migraine treatment. We carried out a systematic review of the studies evaluating the involvement of RAS in patients with migraine. There is evidence from genetic studies exploring the relation between migraine and RAS-related genes and from clinical trials evaluating the efficacy of Angiotensin II Type 1 (AT1) recept...
Source: Protein and Peptide Letters - January 29, 2020 Category: Biochemistry Authors: Sassi KLM, Martins LB, de Miranda AS, Teixeira AL Tags: Protein Pept Lett Source Type: research

Recombinant Proteins: Emerging Production Trends and Applications.
PMID: 31939343 [PubMed - in process] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - January 17, 2020 Category: Biochemistry Authors: Khan MS Tags: Protein Pept Lett Source Type: research

Quantifying Serum Derived Differential Expressed and Low Molecular Weight Protein in Breast Cancer patients.
Conclusion: The study demonstrate that the organelle specific, low molecular weighted proteins are significantly important biomarker. That act as strong agents in the prognosis. PMID: 31933440 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - January 10, 2020 Category: Biochemistry Authors: Zafar A, Jabbar M, Manzoor Y, Gulzar H, Hassan SG, Nazir MA, Ain-Ul-Haq, Mustafa G, Sahar R, Masood A, Iqbal A, Hussain M, Hasan M Tags: Protein Pept Lett Source Type: research

The Renin-Angiotensin System in Huntington's disease: Villain or hero?
Abstract Huntington's disease (HD) is an autosomal dominant, progressive neurodegenerative disorder characterized by severe symptoms, including motor impairment, cognitive decline, and psychiatric alterations. Several systems, molecules, and mediators have been associated with the pathophysiology of HD. Among these, there is the Renin-Angiotensin System (RAS), a peptide hormone system that has been associated with the pathology of neuropsychiatric and neurodegenerative disorders. Important alterations in this system have been demonstrated in HD. However, the role of RAS components in HD is still unclear and needs ...
Source: Protein and Peptide Letters - January 10, 2020 Category: Biochemistry Authors: Machado TCG, Guatimosim C, Kangussu LM Tags: Protein Pept Lett Source Type: research

Preface.
PMID: 31840606 [PubMed - in process] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - December 18, 2019 Category: Biochemistry Authors: Dunn BM Tags: Protein Pept Lett Source Type: research

Archeal Di-O-geranylgeranyl glyceryl phosphate synthase of a UbiA superfamily member provides insight into the multiple human diseases.
Abstract One of the unique characteristic features of the domain archaea, are the lipids that form the hydrophobic core of their cell membrane. These membrane lipids are characterized by distinctive isoprenoid biochemistry and the building blocks are two core lipid structures, sn-2,3-diphytanyl glycerol diether (archaeol) and sn-2,3-dibiphytanyl diglycerol tetraether (caldarchaeol). Archaeol has two phytanyl chains (C20) in a bilayer structure connected to the glycerol moiety by an ether bond. The enzyme involved in this bilayer formation is Di-O-geranylgeranyl glyceryl phosphate synthase (DGGGPS), which is a memb...
Source: Protein and Peptide Letters - December 9, 2019 Category: Biochemistry Authors: Boral D, Rao VK, Ramasamy S Tags: Protein Pept Lett Source Type: research

Investigation on the interaction between Tetrakis (4-carboxylphenyl) porphyrin and CopC by spectroscopy and docking methods.
CONCLUSION: The results revealed that TCPP can form 1:1 complex with CopC, and the binding constant has been calculated to be (5.88±0.12) × 105 M-1. In addition, it was revealed that TCPP quench the fluorescence of CopC by the static quenching mechanism and the binding site n equals one. The formation of CopC-TCPP complex depended on the hydrophobic force and the distance between TCPP and tryptophan residue in CopC was 2.07 nm. PMID: 31800380 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - December 4, 2019 Category: Biochemistry Authors: Song Z, Liu J, Yuan W, Bai Z, Gao N Tags: Protein Pept Lett Source Type: research

Effect of glyoxal modification on a critical arginine residue (Arg-31 α) of hemoglobin: physiological implications of advanced glycated end product.
CONCLUSION: Increased level of glyoxal in diabetes mellitus as well as its high reactivity may cause modifications of the heme protein. Thus, considering the significance of glyoxal-induced protein modification under physiological conditions, the observation appears clinically relevant in terms of understanding hydroimidazolone-mediated protein modification under in vivo conditions. PMID: 31774041 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 24, 2019 Category: Biochemistry Authors: Banerjee S Tags: Protein Pept Lett Source Type: research

Corrigendum.
Authors: Abstract Advances in Usage of Venom Proteins as Diagnostics and Therapeutic Mediators. Protein Pept. Lett., 2018, 25(7), 610-611. The editorial was co-written by Dr. Farid Menaa and Dr. Barkat A. Khan along with the Guest Editor Dr. Samiullah Khan. It has been recently noticed that the Editorial is not showed in the publications list of Dr. Farid Menaa and Dr. Barkat A. Khan in the scientific databases. Therefore, the Editorial has been revised with, all the authors and their affiliations now mentioned in author's list of Editorial. PMID: 31741431 [PubMed - in process] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 21, 2019 Category: Biochemistry Tags: Protein Pept Lett Source Type: research

Identification of Indium Tin Oxide Nanoparticle-Binding Peptides via Phage Display and Biopanning Under Various Buffer Conditions.
Abstract Recent advances in biotechnology have enabled the rapid identification of peptides that bind to inorganic materials. Here, we aimed to identify peptides that bind to indium tin oxide (ITO) nanoparticles via different binding mechanisms, using phage display and biopanning, under five different buffer conditions. Three types of ITO-binding peptides (ITOBPs) were selected from 10 types of identified peptide candidates for characterization. These included ITOBP8, which had an acidic isoelectric point, and was identified when a buffer containing guanidine was used, and ITOBP6 and ITOBP7, which contained a His-...
Source: Protein and Peptide Letters - November 13, 2019 Category: Biochemistry Authors: Nakazawa H, Umetsu M, Tatsuya H, Hattori T, Kumagai I Tags: Protein Pept Lett Source Type: research

Separation of the epitopes in a multi-epitope chimera: Helical or flexible linkers?
CONCLUSION: This investigation illustrated the key role of linker design in determining the expression level of multi-epitope chimera and conformational folding. PMID: 31721685 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 12, 2019 Category: Biochemistry Authors: Kabiri M, Tafaghodi M, Saberi MR, Moghadam M, Rezaee SA, Sankian M Tags: Protein Pept Lett Source Type: research

The effects of amoxicillin, cefazolin, and gentamicin antibiotics on the antioxidant system in mice heart tissues.
CONCLUSION: As a result, it was concluded that amoxicillin and cefazolin caused oxidative stress in the heart, however, gentamicin did not cause any effects. PMID: 31721686 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 12, 2019 Category: Biochemistry Authors: Savcı A, Koçpınar EF, Budak H, Şişecioğlu M, Çiftci M Tags: Protein Pept Lett Source Type: research

Purification, Biochemical Characterization and Decolorization Efficiency of Laccases from Peach and Cherry Cultures of Pleutorus eryngii: A Comparative Study.
CONCLUSION: The results clearly indicated that the performances of Lacs from both cultures in decolorization application are different from each other depending their activities, biochemical and kinetic characteristics. PMID: 31721687 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 12, 2019 Category: Biochemistry Authors: Akpinar M, Urek RO Tags: Protein Pept Lett Source Type: research

NeuroCS: A Tool to Predict Cleavage Sites of Neuropeptide Precursors.
CONCLUSION: The performance of the developed model was decent. Moreover, for users' convenience, an online web server called NeuroCS is built, which is freely available at http://i.uestc.edu.cn/NeuroCS/dist/index.html#/. NeuroCS can be used to predict neuropeptide precursors' cleavage sites effectively. PMID: 31721688 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 12, 2019 Category: Biochemistry Authors: Wang Y, Huang J, Kang J, Li N, Zhou Y, Tang Z, He B Tags: Protein Pept Lett Source Type: research

Analysis of Protein-protein Interaction Networks through Computational Approaches.
Abstract The interactions among proteins and genes are extremely important for cellular functions. Molecular interactions at protein or gene levels can be used to construct interaction networks in which the interacting species are categorized based on direct interactions or functional similarities. Compared with the limited experimental techniques, various computational tools make it possible to analyze, filter, and combine the interaction data to get comprehensive information about the biological pathways. By the efficient way of integrating experimental findings in discovering PPIs and computational techniques f...
Source: Protein and Peptide Letters - November 5, 2019 Category: Biochemistry Authors: Han Y, Cheng L, Sun W Tags: Protein Pept Lett Source Type: research

N ε-acetyl L-α lysine Improves Activity and Stability of α-amylase at Acidic Conditions: a Comparative Study with other Osmolytes.
CONCLUSION: Such significant protective effects on both activity and stability of α-amylase imparted by addition of Nε-acetyl L-α lysine and ectoine at acidic conditions make these osmolytes interesting candidates for biotechnological applications. PMID: 31692420 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 5, 2019 Category: Biochemistry Authors: Joghee NN, Jayaraman G, Selladurai M Tags: Protein Pept Lett Source Type: research

Biophysical characterization of interaction between E. coli alanyl-tRNA synethase with its promoter DNA.
CONCLUSION: In this study it was concluded that full length E. coli Alanyl-tRNA synthetase undergoes a conformational change in presence of its promoter DNA leading to formation of higher order structures. However, the exact mechanism behind this binding is currently unknown and beyond the scope of this study. PMID: 31686635 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 4, 2019 Category: Biochemistry Authors: Banerjee B, Ganguli S, Banerjee R Tags: Protein Pept Lett Source Type: research

Solvent Perturbation of Protein Structures - A Review Study with Lectins.
CONCLUSION: Lectins were mainly perturbed by two fluoroalcohols - 2,2,2-trifluoroethanol and 1,1,1,3,3,3-hexafluoroisopropanol whereas glycerol, ethylene glycol and PEGs were used in some cases. Overall, all native lectins were denatured by alcohols and most of the denatured lectins have predominant helical secondary structure. But characterization of the helical states and the transition pathway for various lectins revealed diverse result. PMID: 31682206 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 4, 2019 Category: Biochemistry Authors: Mandal P, Molla AR Tags: Protein Pept Lett Source Type: research

Characterization of an Intermediate Filament Protein from the Platyhelminth, Dugesia japonica.
CONCLUSIONS: Together with data from other histological studies, our results suggest that Djf-1 is expressed specifically in anchor cells within the glandular adhesive organs of the worm and that Djf-1 IFs may play a role in protecting the cells from mechanical stress. PMID: 31652112 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 24, 2019 Category: Biochemistry Authors: Yamamoto A, Matsunaga KI, Anai T, Kawano H, Ueda T, Matsumoto T, Ando S Tags: Protein Pept Lett Source Type: research

Mass Spectrometry based Identification of Urinary Antimicrobial Peptides in Dairy Cows.
CONCLUSION: This study concludes that cow urine, previously unexplored with regard to antimicrobial peptides, would be a promising source of highly potent AMPs and an effective alternative to the resistant antibiotics. PMID: 31654508 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 24, 2019 Category: Biochemistry Authors: Sharma A, Nigam R, Kumar A, Singh S Tags: Protein Pept Lett Source Type: research

Recent advances on the semi-supervised learning for long non-coding RNA-protein interactions prediction :a review.
CONCLUSION: In this review, we summarize several computational models of the lncRNA protein interactions prediction base on semi-supervised learning during the past two years, and introduce their advantages and shortcomings briefly. Finally, the future research directions of lncRNA protein interaction prediction are pointed out. PMID: 31654509 [PubMed - as supplied by publisher] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 24, 2019 Category: Biochemistry Authors: Zhong L, Ming Z, Xie G, Fan C, Piao X Tags: Protein Pept Lett Source Type: research

Editorial.
Abstract PMID: 31618169 [PubMed - in process] (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 18, 2019 Category: Biochemistry Authors: Dunn BM Tags: Protein Pept Lett Source Type: research