Crystal Structure Determination of Nucleotide-sugar Binding Domain of Human UDP-glucuronosyltransferases 2B10
CONCLUSION: The crystal structure of UGT2B10 CTD was solved at a high resolution of 1.53 Å, revealing a conserved cofactor binding pocket. This is the first study determining the C-terminal cofactor binding domain of human UGT2B10, which plays a key role in additive drug metabolism.PMID:37946357 | DOI:10.2174/0109298665255492231020050937 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 10, 2023 Category: Biochemistry Authors: Xinli Yin Xi Lu Xudan Qi Yuxi Tu Na Zhang Yuan Yang Xiabin Chen Junsen Tong Source Type: research
Evaluation of Cytotoxicity and Antimicrobial Activity of Experimental Composites Containing Chitosan-Silver Oxide Particles Against Two Main Pathogenic Bacteria in Periodontal Disease
CONCLUSION: The experimental composite containing CH-Ag2O 60 showed the greatest antibacterial properties against two periodontal pathogens evaluated. In order to clarify the clinical significance of composite cytotoxicity, further clinical studies are necessary.PMID:37921156 | DOI:10.2174/0109298665240242231016103321 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Nahid Nasrabadi Navid Ramezanian Parisa Ghorbanian Ali Forouzanfar Hamideh Sadat Mohammadipour Source Type: research
Activation and Denitrosylation of Procaspase-3 in KA-induced Excitotoxicity
CONCLUSIONS: KA led to denitrosylation and activation of procaspase-3 via FasL and TrxR. Inhibition of procaspase-3 denitrosylation by auranofin, SNP, and GSNO played protective effects against KA-induced apoptosis-like neuronal death in rat hippocampal CA1 and CA3 subfields. These investigations revealed that the procaspase-3 undergoes an initial denitrosylation process before becoming activated, providing valuable insights into the underlying mechanisms and possible treatment of excitotoxicity.PMID:37921157 | DOI:10.2174/0109298665261164231019043521 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Yong Liu Hui Yan Jia Zhang Yu-Ting Cai Xiao-Hui Yin Feng Lu Ying-Kui Liu Chong Li Source Type: research
Evaluation of Cytotoxicity and Antimicrobial Activity of Experimental Composites Containing Chitosan-Silver Oxide Particles Against Two Main Pathogenic Bacteria in Periodontal Disease
CONCLUSION: The experimental composite containing CH-Ag2O 60 showed the greatest antibacterial properties against two periodontal pathogens evaluated. In order to clarify the clinical significance of composite cytotoxicity, further clinical studies are necessary.PMID:37921156 | DOI:10.2174/0109298665240242231016103321 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Nahid Nasrabadi Navid Ramezanian Parisa Ghorbanian Ali Forouzanfar Hamideh Sadat Mohammadipour Source Type: research
Activation and Denitrosylation of Procaspase-3 in KA-induced Excitotoxicity
CONCLUSIONS: KA led to denitrosylation and activation of procaspase-3 via FasL and TrxR. Inhibition of procaspase-3 denitrosylation by auranofin, SNP, and GSNO played protective effects against KA-induced apoptosis-like neuronal death in rat hippocampal CA1 and CA3 subfields. These investigations revealed that the procaspase-3 undergoes an initial denitrosylation process before becoming activated, providing valuable insights into the underlying mechanisms and possible treatment of excitotoxicity.PMID:37921157 | DOI:10.2174/0109298665261164231019043521 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Yong Liu Hui Yan Jia Zhang Yu-Ting Cai Xiao-Hui Yin Feng Lu Ying-Kui Liu Chong Li Source Type: research
Evaluation of Cytotoxicity and Antimicrobial Activity of Experimental Composites Containing Chitosan-Silver Oxide Particles Against Two Main Pathogenic Bacteria in Periodontal Disease
CONCLUSION: The experimental composite containing CH-Ag2O 60 showed the greatest antibacterial properties against two periodontal pathogens evaluated. In order to clarify the clinical significance of composite cytotoxicity, further clinical studies are necessary.PMID:37921156 | DOI:10.2174/0109298665240242231016103321 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Nahid Nasrabadi Navid Ramezanian Parisa Ghorbanian Ali Forouzanfar Hamideh Sadat Mohammadipour Source Type: research
Activation and Denitrosylation of Procaspase-3 in KA-induced Excitotoxicity
CONCLUSIONS: KA led to denitrosylation and activation of procaspase-3 via FasL and TrxR. Inhibition of procaspase-3 denitrosylation by auranofin, SNP, and GSNO played protective effects against KA-induced apoptosis-like neuronal death in rat hippocampal CA1 and CA3 subfields. These investigations revealed that the procaspase-3 undergoes an initial denitrosylation process before becoming activated, providing valuable insights into the underlying mechanisms and possible treatment of excitotoxicity.PMID:37921157 | DOI:10.2174/0109298665261164231019043521 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Yong Liu Hui Yan Jia Zhang Yu-Ting Cai Xiao-Hui Yin Feng Lu Ying-Kui Liu Chong Li Source Type: research
Evaluation of Cytotoxicity and Antimicrobial Activity of Experimental Composites Containing Chitosan-Silver Oxide Particles Against Two Main Pathogenic Bacteria in Periodontal Disease
CONCLUSION: The experimental composite containing CH-Ag2O 60 showed the greatest antibacterial properties against two periodontal pathogens evaluated. In order to clarify the clinical significance of composite cytotoxicity, further clinical studies are necessary.PMID:37921156 | DOI:10.2174/0109298665240242231016103321 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Nahid Nasrabadi Navid Ramezanian Parisa Ghorbanian Ali Forouzanfar Hamideh Sadat Mohammadipour Source Type: research
Activation and Denitrosylation of Procaspase-3 in KA-induced Excitotoxicity
CONCLUSIONS: KA led to denitrosylation and activation of procaspase-3 via FasL and TrxR. Inhibition of procaspase-3 denitrosylation by auranofin, SNP, and GSNO played protective effects against KA-induced apoptosis-like neuronal death in rat hippocampal CA1 and CA3 subfields. These investigations revealed that the procaspase-3 undergoes an initial denitrosylation process before becoming activated, providing valuable insights into the underlying mechanisms and possible treatment of excitotoxicity.PMID:37921157 | DOI:10.2174/0109298665261164231019043521 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Yong Liu Hui Yan Jia Zhang Yu-Ting Cai Xiao-Hui Yin Feng Lu Ying-Kui Liu Chong Li Source Type: research
Evaluation of Cytotoxicity and Antimicrobial Activity of Experimental Composites Containing Chitosan-Silver Oxide Particles Against Two Main Pathogenic Bacteria in Periodontal Disease
CONCLUSION: The experimental composite containing CH-Ag2O 60 showed the greatest antibacterial properties against two periodontal pathogens evaluated. In order to clarify the clinical significance of composite cytotoxicity, further clinical studies are necessary.PMID:37921156 | DOI:10.2174/0109298665240242231016103321 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Nahid Nasrabadi Navid Ramezanian Parisa Ghorbanian Ali Forouzanfar Hamideh Sadat Mohammadipour Source Type: research
Activation and Denitrosylation of Procaspase-3 in KA-induced Excitotoxicity
CONCLUSIONS: KA led to denitrosylation and activation of procaspase-3 via FasL and TrxR. Inhibition of procaspase-3 denitrosylation by auranofin, SNP, and GSNO played protective effects against KA-induced apoptosis-like neuronal death in rat hippocampal CA1 and CA3 subfields. These investigations revealed that the procaspase-3 undergoes an initial denitrosylation process before becoming activated, providing valuable insights into the underlying mechanisms and possible treatment of excitotoxicity.PMID:37921157 | DOI:10.2174/0109298665261164231019043521 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Yong Liu Hui Yan Jia Zhang Yu-Ting Cai Xiao-Hui Yin Feng Lu Ying-Kui Liu Chong Li Source Type: research
Evaluation of Cytotoxicity and Antimicrobial Activity of Experimental Composites Containing Chitosan-Silver Oxide Particles Against Two Main Pathogenic Bacteria in Periodontal Disease
CONCLUSION: The experimental composite containing CH-Ag2O 60 showed the greatest antibacterial properties against two periodontal pathogens evaluated. In order to clarify the clinical significance of composite cytotoxicity, further clinical studies are necessary.PMID:37921156 | DOI:10.2174/0109298665240242231016103321 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Nahid Nasrabadi Navid Ramezanian Parisa Ghorbanian Ali Forouzanfar Hamideh Sadat Mohammadipour Source Type: research
Activation and Denitrosylation of Procaspase-3 in KA-induced Excitotoxicity
CONCLUSIONS: KA led to denitrosylation and activation of procaspase-3 via FasL and TrxR. Inhibition of procaspase-3 denitrosylation by auranofin, SNP, and GSNO played protective effects against KA-induced apoptosis-like neuronal death in rat hippocampal CA1 and CA3 subfields. These investigations revealed that the procaspase-3 undergoes an initial denitrosylation process before becoming activated, providing valuable insights into the underlying mechanisms and possible treatment of excitotoxicity.PMID:37921157 | DOI:10.2174/0109298665261164231019043521 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Yong Liu Hui Yan Jia Zhang Yu-Ting Cai Xiao-Hui Yin Feng Lu Ying-Kui Liu Chong Li Source Type: research
Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research
Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research
