Activation and Denitrosylation of Procaspase-3 in KA-induced Excitotoxicity
CONCLUSIONS: KA led to denitrosylation and activation of procaspase-3 via FasL and TrxR. Inhibition of procaspase-3 denitrosylation by auranofin, SNP, and GSNO played protective effects against KA-induced apoptosis-like neuronal death in rat hippocampal CA1 and CA3 subfields. These investigations revealed that the procaspase-3 undergoes an initial denitrosylation process before becoming activated, providing valuable insights into the underlying mechanisms and possible treatment of excitotoxicity.PMID:37921157 | DOI:10.2174/0109298665261164231019043521 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Yong Liu Hui Yan Jia Zhang Yu-Ting Cai Xiao-Hui Yin Feng Lu Ying-Kui Liu Chong Li Source Type: research

Evaluation of Cytotoxicity and Antimicrobial Activity of Experimental Composites Containing Chitosan-Silver Oxide Particles Against Two Main Pathogenic Bacteria in Periodontal Disease
CONCLUSION: The experimental composite containing CH-Ag2O 60 showed the greatest antibacterial properties against two periodontal pathogens evaluated. In order to clarify the clinical significance of composite cytotoxicity, further clinical studies are necessary.PMID:37921156 | DOI:10.2174/0109298665240242231016103321 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Nahid Nasrabadi Navid Ramezanian Parisa Ghorbanian Ali Forouzanfar Hamideh Sadat Mohammadipour Source Type: research

Activation and Denitrosylation of Procaspase-3 in KA-induced Excitotoxicity
CONCLUSIONS: KA led to denitrosylation and activation of procaspase-3 via FasL and TrxR. Inhibition of procaspase-3 denitrosylation by auranofin, SNP, and GSNO played protective effects against KA-induced apoptosis-like neuronal death in rat hippocampal CA1 and CA3 subfields. These investigations revealed that the procaspase-3 undergoes an initial denitrosylation process before becoming activated, providing valuable insights into the underlying mechanisms and possible treatment of excitotoxicity.PMID:37921157 | DOI:10.2174/0109298665261164231019043521 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Yong Liu Hui Yan Jia Zhang Yu-Ting Cai Xiao-Hui Yin Feng Lu Ying-Kui Liu Chong Li Source Type: research

Evaluation of Cytotoxicity and Antimicrobial Activity of Experimental Composites Containing Chitosan-Silver Oxide Particles Against Two Main Pathogenic Bacteria in Periodontal Disease
CONCLUSION: The experimental composite containing CH-Ag2O 60 showed the greatest antibacterial properties against two periodontal pathogens evaluated. In order to clarify the clinical significance of composite cytotoxicity, further clinical studies are necessary.PMID:37921156 | DOI:10.2174/0109298665240242231016103321 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Nahid Nasrabadi Navid Ramezanian Parisa Ghorbanian Ali Forouzanfar Hamideh Sadat Mohammadipour Source Type: research

Activation and Denitrosylation of Procaspase-3 in KA-induced Excitotoxicity
CONCLUSIONS: KA led to denitrosylation and activation of procaspase-3 via FasL and TrxR. Inhibition of procaspase-3 denitrosylation by auranofin, SNP, and GSNO played protective effects against KA-induced apoptosis-like neuronal death in rat hippocampal CA1 and CA3 subfields. These investigations revealed that the procaspase-3 undergoes an initial denitrosylation process before becoming activated, providing valuable insights into the underlying mechanisms and possible treatment of excitotoxicity.PMID:37921157 | DOI:10.2174/0109298665261164231019043521 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - November 3, 2023 Category: Biochemistry Authors: Yong Liu Hui Yan Jia Zhang Yu-Ting Cai Xiao-Hui Yin Feng Lu Ying-Kui Liu Chong Li Source Type: research

Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research

Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research

Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research

Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research

Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research

Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research

Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research

Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research

Hsa_circ_0001687 Function as a ceRNA to Facilitate Hepatocellular Carcinoma Progression via miR-140- 3p/FOXQ1 Axis
CONCLUSION: This research indicated the role of circ_0001687/miR-140-3p/FOXQ1 network in regulating HCC development. These may provide new insights into the treatment of HCC.PMID:37870056 | DOI:10.2174/0109298665238824231012072118 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 23, 2023 Category: Biochemistry Authors: Song You Niangmei Cheng Fei Wang Xiaoyuan Zheng Yingchao Wang Bixing Zhao Jingfeng Liu Source Type: research

VEGF165b Mutant Promotes the Apoptosis of Murine Breast Cancer Cells Induced by Paclitaxel by Inducing Tumor Vessel Maturation
CONCLUSION: Immunohistochemistry and the TUNEL assay showed that mVEGF165b and bevacizumab combined with paclitaxel-induced higher vascular maturity and more apoptosis than paclitaxel alone. mVEGF165b showed similar efficacy and mechanism of action as bevacizumab, indicating its potential to be developed into a safe and effective anti-angiogenic drug.PMID:37861033 | DOI:10.2174/0109298665256010230919062456 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - October 20, 2023 Category: Biochemistry Authors: Liang Chen Li Youwei Guo Enhui Bai Shuge Wang Yan Zhang Huiyong Source Type: research