Exogenous apelin-13 administration ameliorates cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in rat lungs
CONCLUSION: Exogenous Apelin-13 treatment protected lung tissue against injury by inhibiting cyclophosphamide-induced oxidative stress, inflammation, and apoptosis. This protective effect of apelin-13 was accompanied by upregulation of the Sirt1 and downregulation of NF-kB/p53 in the lungs.PMID:37622713 | DOI:10.2174/0929866530666230824142516 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Arzu Keskin-Aktan Özden Kutlay Source Type: research

Binding Affinity Studies of Nicotinamide N-methyltransferase and Ligands by Saturation Transfer Difference NMR
CONCLUSION: The binding affinity of nicotinamide and SAH to NNMT and its mutants were obtained by STD NMR in this study. It was found that nicotinamide and SAH bind to WT in a particular orientation, and Y20 is critical for their binding orientation and affinity to NNMT.PMID:37622714 | DOI:10.2174/0929866530666230824153356 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Tingting Fang Jianyu Zhang Source Type: research

Biochemical Aspects of the Spiral Grain Formation in Scots Pine (Pinus Sylvestris L.) Wood. Some Differences and Similarities with Biochemical Indicators of Abnormal Xylogenesis in Karelian Birch (Betula Pendula Roth Var. Carelica (Mercl.) H ämet-Ahti)
CONCLUSION: The study showed that the differences in the AOS enzyme's activity in P. sylvestris during the formation of straight-grained and spiral-grained wood were revealed for the first time. The increased CAT, POD and PPO activities in xylem with a decrease in SS and an increase in ApInv during spiral-grained wood formation can be biochemical markers of these structural anomalies. Metabolic regularities found in the AOS enzyme complex during spiral-grained wood formation do not contradict those found earlier during figured wood formation in B. pendula var. carelica. The identified patterns can form the base for diagnos...
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Kseniya Mihajlovna Nikerova Natalia Alekseevna Galibina Sergey Mihajlovich Sinkevich Irina Nikolaevna Sofronova Marina Nikolaevna Borodina Yuliya Leonidovna Moshchenskaya Tatiana Vladimirovna Tarelkina Anna Vladimirovna Klimova Source Type: research

Exogenous apelin-13 administration ameliorates cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in rat lungs
CONCLUSION: Exogenous Apelin-13 treatment protected lung tissue against injury by inhibiting cyclophosphamide-induced oxidative stress, inflammation, and apoptosis. This protective effect of apelin-13 was accompanied by upregulation of the Sirt1 and downregulation of NF-kB/p53 in the lungs.PMID:37622713 | DOI:10.2174/0929866530666230824142516 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Arzu Keskin-Aktan Özden Kutlay Source Type: research

Binding Affinity Studies of Nicotinamide N-methyltransferase and Ligands by Saturation Transfer Difference NMR
CONCLUSION: The binding affinity of nicotinamide and SAH to NNMT and its mutants were obtained by STD NMR in this study. It was found that nicotinamide and SAH bind to WT in a particular orientation, and Y20 is critical for their binding orientation and affinity to NNMT.PMID:37622714 | DOI:10.2174/0929866530666230824153356 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Tingting Fang Jianyu Zhang Source Type: research

Biochemical Aspects of the Spiral Grain Formation in Scots Pine (Pinus Sylvestris L.) Wood. Some Differences and Similarities with Biochemical Indicators of Abnormal Xylogenesis in Karelian Birch (Betula Pendula Roth Var. Carelica (Mercl.) H ämet-Ahti)
CONCLUSION: The study showed that the differences in the AOS enzyme's activity in P. sylvestris during the formation of straight-grained and spiral-grained wood were revealed for the first time. The increased CAT, POD and PPO activities in xylem with a decrease in SS and an increase in ApInv during spiral-grained wood formation can be biochemical markers of these structural anomalies. Metabolic regularities found in the AOS enzyme complex during spiral-grained wood formation do not contradict those found earlier during figured wood formation in B. pendula var. carelica. The identified patterns can form the base for diagnos...
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Kseniya Mihajlovna Nikerova Natalia Alekseevna Galibina Sergey Mihajlovich Sinkevich Irina Nikolaevna Sofronova Marina Nikolaevna Borodina Yuliya Leonidovna Moshchenskaya Tatiana Vladimirovna Tarelkina Anna Vladimirovna Klimova Source Type: research

Exogenous apelin-13 administration ameliorates cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in rat lungs
CONCLUSION: Exogenous Apelin-13 treatment protected lung tissue against injury by inhibiting cyclophosphamide-induced oxidative stress, inflammation, and apoptosis. This protective effect of apelin-13 was accompanied by upregulation of the Sirt1 and downregulation of NF-kB/p53 in the lungs.PMID:37622713 | DOI:10.2174/0929866530666230824142516 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Arzu Keskin-Aktan Özden Kutlay Source Type: research

Binding Affinity Studies of Nicotinamide N-methyltransferase and Ligands by Saturation Transfer Difference NMR
CONCLUSION: The binding affinity of nicotinamide and SAH to NNMT and its mutants were obtained by STD NMR in this study. It was found that nicotinamide and SAH bind to WT in a particular orientation, and Y20 is critical for their binding orientation and affinity to NNMT.PMID:37622714 | DOI:10.2174/0929866530666230824153356 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Tingting Fang Jianyu Zhang Source Type: research

Biochemical Aspects of the Spiral Grain Formation in Scots Pine (Pinus Sylvestris L.) Wood. Some Differences and Similarities with Biochemical Indicators of Abnormal Xylogenesis in Karelian Birch (Betula Pendula Roth Var. Carelica (Mercl.) H ämet-Ahti)
CONCLUSION: The study showed that the differences in the AOS enzyme's activity in P. sylvestris during the formation of straight-grained and spiral-grained wood were revealed for the first time. The increased CAT, POD and PPO activities in xylem with a decrease in SS and an increase in ApInv during spiral-grained wood formation can be biochemical markers of these structural anomalies. Metabolic regularities found in the AOS enzyme complex during spiral-grained wood formation do not contradict those found earlier during figured wood formation in B. pendula var. carelica. The identified patterns can form the base for diagnos...
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Kseniya Mihajlovna Nikerova Natalia Alekseevna Galibina Sergey Mihajlovich Sinkevich Irina Nikolaevna Sofronova Marina Nikolaevna Borodina Yuliya Leonidovna Moshchenskaya Tatiana Vladimirovna Tarelkina Anna Vladimirovna Klimova Source Type: research

Exogenous apelin-13 administration ameliorates cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in rat lungs
CONCLUSION: Exogenous Apelin-13 treatment protected lung tissue against injury by inhibiting cyclophosphamide-induced oxidative stress, inflammation, and apoptosis. This protective effect of apelin-13 was accompanied by upregulation of the Sirt1 and downregulation of NF-kB/p53 in the lungs.PMID:37622713 | DOI:10.2174/0929866530666230824142516 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Arzu Keskin-Aktan Özden Kutlay Source Type: research

Binding Affinity Studies of Nicotinamide N-methyltransferase and Ligands by Saturation Transfer Difference NMR
CONCLUSION: The binding affinity of nicotinamide and SAH to NNMT and its mutants were obtained by STD NMR in this study. It was found that nicotinamide and SAH bind to WT in a particular orientation, and Y20 is critical for their binding orientation and affinity to NNMT.PMID:37622714 | DOI:10.2174/0929866530666230824153356 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Tingting Fang Jianyu Zhang Source Type: research

Biochemical Aspects of the Spiral Grain Formation in Scots Pine (Pinus Sylvestris L.) Wood. Some Differences and Similarities with Biochemical Indicators of Abnormal Xylogenesis in Karelian Birch (Betula Pendula Roth Var. Carelica (Mercl.) H ämet-Ahti)
CONCLUSION: The study showed that the differences in the AOS enzyme's activity in P. sylvestris during the formation of straight-grained and spiral-grained wood were revealed for the first time. The increased CAT, POD and PPO activities in xylem with a decrease in SS and an increase in ApInv during spiral-grained wood formation can be biochemical markers of these structural anomalies. Metabolic regularities found in the AOS enzyme complex during spiral-grained wood formation do not contradict those found earlier during figured wood formation in B. pendula var. carelica. The identified patterns can form the base for diagnos...
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Kseniya Mihajlovna Nikerova Natalia Alekseevna Galibina Sergey Mihajlovich Sinkevich Irina Nikolaevna Sofronova Marina Nikolaevna Borodina Yuliya Leonidovna Moshchenskaya Tatiana Vladimirovna Tarelkina Anna Vladimirovna Klimova Source Type: research

Exogenous apelin-13 administration ameliorates cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in rat lungs
CONCLUSION: Exogenous Apelin-13 treatment protected lung tissue against injury by inhibiting cyclophosphamide-induced oxidative stress, inflammation, and apoptosis. This protective effect of apelin-13 was accompanied by upregulation of the Sirt1 and downregulation of NF-kB/p53 in the lungs.PMID:37622713 | DOI:10.2174/0929866530666230824142516 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Arzu Keskin-Aktan Özden Kutlay Source Type: research

Binding Affinity Studies of Nicotinamide N-methyltransferase and Ligands by Saturation Transfer Difference NMR
CONCLUSION: The binding affinity of nicotinamide and SAH to NNMT and its mutants were obtained by STD NMR in this study. It was found that nicotinamide and SAH bind to WT in a particular orientation, and Y20 is critical for their binding orientation and affinity to NNMT.PMID:37622714 | DOI:10.2174/0929866530666230824153356 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Tingting Fang Jianyu Zhang Source Type: research

Biochemical Aspects of the Spiral Grain Formation in Scots Pine (Pinus Sylvestris L.) Wood. Some Differences and Similarities with Biochemical Indicators of Abnormal Xylogenesis in Karelian Birch (Betula Pendula Roth Var. Carelica (Mercl.) H ämet-Ahti)
CONCLUSION: The study showed that the differences in the AOS enzyme's activity in P. sylvestris during the formation of straight-grained and spiral-grained wood were revealed for the first time. The increased CAT, POD and PPO activities in xylem with a decrease in SS and an increase in ApInv during spiral-grained wood formation can be biochemical markers of these structural anomalies. Metabolic regularities found in the AOS enzyme complex during spiral-grained wood formation do not contradict those found earlier during figured wood formation in B. pendula var. carelica. The identified patterns can form the base for diagnos...
Source: Protein and Peptide Letters - August 25, 2023 Category: Biochemistry Authors: Kseniya Mihajlovna Nikerova Natalia Alekseevna Galibina Sergey Mihajlovich Sinkevich Irina Nikolaevna Sofronova Marina Nikolaevna Borodina Yuliya Leonidovna Moshchenskaya Tatiana Vladimirovna Tarelkina Anna Vladimirovna Klimova Source Type: research