Genome sequencing and assembly of Indian golden silkmoth, Antheraea assamensis Helfer (Saturniidae, Lepidoptera)
This study provides valuable insights into the molecular basis of evolutionary divergence and adaptations in muga silkmoth. The genome assembly reported in this study will significantly help in the functional genomics studies on A. assamensis and other Antheraea species along with comparative genomics analyses of Bombycoidea insects.PMID:38599255 | DOI:10.1016/j.ygeno.2024.110841 (Source: Genomics)
Source: Genomics - April 10, 2024 Category: Genetics & Stem Cells Authors: Himanshu Dubey A R Pradeep Kartik Neog Rajal Debnath P J Aneesha Suraj Kumar Shah Indumathi Kamatchi K M Ponnuvel A Ramesha Kunjupillai Vijayan Upendra Nongthomba Utpal Bora Sivaprasad Vankadara K M VijayaKumari Kallare P Arunkumar Source Type: research
Genome sequencing and assembly of Indian golden silkmoth, Antheraea assamensis Helfer (Saturniidae, Lepidoptera)
This study provides valuable insights into the molecular basis of evolutionary divergence and adaptations in muga silkmoth. The genome assembly reported in this study will significantly help in the functional genomics studies on A. assamensis and other Antheraea species along with comparative genomics analyses of Bombycoidea insects.PMID:38599255 | DOI:10.1016/j.ygeno.2024.110841 (Source: Genomics)
Source: Genomics - April 10, 2024 Category: Genetics & Stem Cells Authors: Himanshu Dubey A R Pradeep Kartik Neog Rajal Debnath P J Aneesha Suraj Kumar Shah Indumathi Kamatchi K M Ponnuvel A Ramesha Kunjupillai Vijayan Upendra Nongthomba Utpal Bora Sivaprasad Vankadara K M VijayaKumari Kallare P Arunkumar Source Type: research
Variants in FOXC1 and FOXC2 identified in patients with conotruncal heart defects
Genomics. 2024 Apr 3;116(3):110840. doi: 10.1016/j.ygeno.2024.110840. Online ahead of print.ABSTRACTConotruncal heart defects (CTD), subtypes of congenital heart disease, result from abnormal cardiac outflow tract development (OFT). FOXC1 and FOXC2 are closely related members of the forkhead transcription factor family and play essential roles in the development of OFT. We confirmed their expression pattern in mouse and human embryos, identifying four variants in FOXC1 and three in FOXC2 by screening these two genes in 605 patients with sporadic CTD. Western blot demonstrated expression levels, while Dual-luciferase report...
Source: Genomics - April 5, 2024 Category: Genetics & Stem Cells Authors: Wei Wei Bojian Li Fen Li Kun Sun Xuechao Jiang Rang Xu Source Type: research
Variants in FOXC1 and FOXC2 identified in patients with conotruncal heart defects
Genomics. 2024 Apr 3;116(3):110840. doi: 10.1016/j.ygeno.2024.110840. Online ahead of print.ABSTRACTConotruncal heart defects (CTD), subtypes of congenital heart disease, result from abnormal cardiac outflow tract development (OFT). FOXC1 and FOXC2 are closely related members of the forkhead transcription factor family and play essential roles in the development of OFT. We confirmed their expression pattern in mouse and human embryos, identifying four variants in FOXC1 and three in FOXC2 by screening these two genes in 605 patients with sporadic CTD. Western blot demonstrated expression levels, while Dual-luciferase report...
Source: Genomics - April 5, 2024 Category: Genetics & Stem Cells Authors: Wei Wei Bojian Li Fen Li Kun Sun Xuechao Jiang Rang Xu Source Type: research
Variants in FOXC1 and FOXC2 identified in patients with conotruncal heart defects
Genomics. 2024 Apr 3:110840. doi: 10.1016/j.ygeno.2024.110840. Online ahead of print.ABSTRACTConotruncal heart defects (CTD), subtypes of congenital heart disease, result from abnormal cardiac outflow tract development (OFT). FOXC1 and FOXC2 are closely related members of the forkhead transcription factor family and play essential roles in the development of OFT. We confirmed their expression pattern in mouse and human embryos, identifying four variants in FOXC1 and three in FOXC2 by screening these two genes in 605 patients with sporadic CTD. Western blot demonstrated expression levels, while Dual-luciferase reporter assa...
Source: Genomics - April 5, 2024 Category: Genetics & Stem Cells Authors: Wei Wei Bojian Li Fen Li Kun Sun Xuechao Jiang Rang Xu Source Type: research
Variants in FOXC1 and FOXC2 identified in patients with conotruncal heart defects
Genomics. 2024 Apr 3:110840. doi: 10.1016/j.ygeno.2024.110840. Online ahead of print.ABSTRACTConotruncal heart defects (CTD), subtypes of congenital heart disease, result from abnormal cardiac outflow tract development (OFT). FOXC1 and FOXC2 are closely related members of the forkhead transcription factor family and play essential roles in the development of OFT. We confirmed their expression pattern in mouse and human embryos, identifying four variants in FOXC1 and three in FOXC2 by screening these two genes in 605 patients with sporadic CTD. Western blot demonstrated expression levels, while Dual-luciferase reporter assa...
Source: Genomics - April 5, 2024 Category: Genetics & Stem Cells Authors: Wei Wei Bojian Li Fen Li Kun Sun Xuechao Jiang Rang Xu Source Type: research
De novo assembly and analysis of Sonneratia ovata genome and population analysis
Genomics. 2024 Mar 27;116(3):110837. doi: 10.1016/j.ygeno.2024.110837. Online ahead of print.ABSTRACTMangroves are an important part of coastal and estuarine ecosystems where they serve as nurseries for marine species and prevent coastal erosion. Here we report the genome of Sonneratia ovata, which is a true mangrove that grows in estuarine environments and can tolerate moderate salt exposure. We sequenced the S. ovata genome and assembled it into chromosome-level scaffolds through the use of Hi-C. The genome is 212.3 Mb and contains 12 chromosomes that range in size from 12.2 to 23.2 Mb. Annotation identified 29,829 genes...
Source: Genomics - March 28, 2024 Category: Genetics & Stem Cells Authors: Jeremy R Shearman Chaiwat Naktang Chutima Sonthirod Wasitthee Kongkachana Sonicha U-Thoomporn Nukoon Jomchai Chatree Maknual Suchart Yamprasai Poonsri Wanthongchai Wirulda Pootakham Sithichoke Tangphatsornruang Source Type: research
De novo assembly and analysis of Sonneratia ovata genome and population analysis
Genomics. 2024 Mar 27;116(3):110837. doi: 10.1016/j.ygeno.2024.110837. Online ahead of print.ABSTRACTMangroves are an important part of coastal and estuarine ecosystems where they serve as nurseries for marine species and prevent coastal erosion. Here we report the genome of Sonneratia ovata, which is a true mangrove that grows in estuarine environments and can tolerate moderate salt exposure. We sequenced the S. ovata genome and assembled it into chromosome-level scaffolds through the use of Hi-C. The genome is 212.3 Mb and contains 12 chromosomes that range in size from 12.2 to 23.2 Mb. Annotation identified 29,829 genes...
Source: Genomics - March 28, 2024 Category: Genetics & Stem Cells Authors: Jeremy R Shearman Chaiwat Naktang Chutima Sonthirod Wasitthee Kongkachana Sonicha U-Thoomporn Nukoon Jomchai Chatree Maknual Suchart Yamprasai Poonsri Wanthongchai Wirulda Pootakham Sithichoke Tangphatsornruang Source Type: research
De novo assembly and analysis of Sonneratia ovata genome and population analysis
Genomics. 2024 Mar 27;116(3):110837. doi: 10.1016/j.ygeno.2024.110837. Online ahead of print.ABSTRACTMangroves are an important part of coastal and estuarine ecosystems where they serve as nurseries for marine species and prevent coastal erosion. Here we report the genome of Sonneratia ovata, which is a true mangrove that grows in estuarine environments and can tolerate moderate salt exposure. We sequenced the S. ovata genome and assembled it into chromosome-level scaffolds through the use of Hi-C. The genome is 212.3 Mb and contains 12 chromosomes that range in size from 12.2 to 23.2 Mb. Annotation identified 29,829 genes...
Source: Genomics - March 28, 2024 Category: Genetics & Stem Cells Authors: Jeremy R Shearman Chaiwat Naktang Chutima Sonthirod Wasitthee Kongkachana Sonicha U-Thoomporn Nukoon Jomchai Chatree Maknual Suchart Yamprasai Poonsri Wanthongchai Wirulda Pootakham Sithichoke Tangphatsornruang Source Type: research
De novo assembly and analysis of Sonneratia ovata genome and population analysis
Genomics. 2024 Mar 27;116(3):110837. doi: 10.1016/j.ygeno.2024.110837. Online ahead of print.ABSTRACTMangroves are an important part of coastal and estuarine ecosystems where they serve as nurseries for marine species and prevent coastal erosion. Here we report the genome of Sonneratia ovata, which is a true mangrove that grows in estuarine environments and can tolerate moderate salt exposure. We sequenced the S. ovata genome and assembled it into chromosome-level scaffolds through the use of Hi-C. The genome is 212.3 Mb and contains 12 chromosomes that range in size from 12.2 to 23.2 Mb. Annotation identified 29,829 genes...
Source: Genomics - March 28, 2024 Category: Genetics & Stem Cells Authors: Jeremy R Shearman Chaiwat Naktang Chutima Sonthirod Wasitthee Kongkachana Sonicha U-Thoomporn Nukoon Jomchai Chatree Maknual Suchart Yamprasai Poonsri Wanthongchai Wirulda Pootakham Sithichoke Tangphatsornruang Source Type: research
De novo assembly and analysis of Sonneratia ovata genome and population analysis
Genomics. 2024 Mar 27;116(3):110837. doi: 10.1016/j.ygeno.2024.110837. Online ahead of print.ABSTRACTMangroves are an important part of coastal and estuarine ecosystems where they serve as nurseries for marine species and prevent coastal erosion. Here we report the genome of Sonneratia ovata, which is a true mangrove that grows in estuarine environments and can tolerate moderate salt exposure. We sequenced the S. ovata genome and assembled it into chromosome-level scaffolds through the use of Hi-C. The genome is 212.3 Mb and contains 12 chromosomes that range in size from 12.2 to 23.2 Mb. Annotation identified 29,829 genes...
Source: Genomics - March 28, 2024 Category: Genetics & Stem Cells Authors: Jeremy R Shearman Chaiwat Naktang Chutima Sonthirod Wasitthee Kongkachana Sonicha U-Thoomporn Nukoon Jomchai Chatree Maknual Suchart Yamprasai Poonsri Wanthongchai Wirulda Pootakham Sithichoke Tangphatsornruang Source Type: research
De novo assembly and analysis of Sonneratia ovata genome and population analysis
Genomics. 2024 Mar 27;116(3):110837. doi: 10.1016/j.ygeno.2024.110837. Online ahead of print.ABSTRACTMangroves are an important part of coastal and estuarine ecosystems where they serve as nurseries for marine species and prevent coastal erosion. Here we report the genome of Sonneratia ovata, which is a true mangrove that grows in estuarine environments and can tolerate moderate salt exposure. We sequenced the S. ovata genome and assembled it into chromosome-level scaffolds through the use of Hi-C. The genome is 212.3 Mb and contains 12 chromosomes that range in size from 12.2 to 23.2 Mb. Annotation identified 29,829 genes...
Source: Genomics - March 28, 2024 Category: Genetics & Stem Cells Authors: Jeremy R Shearman Chaiwat Naktang Chutima Sonthirod Wasitthee Kongkachana Sonicha U-Thoomporn Nukoon Jomchai Chatree Maknual Suchart Yamprasai Poonsri Wanthongchai Wirulda Pootakham Sithichoke Tangphatsornruang Source Type: research
De novo assembly and analysis of Sonneratia ovata genome and population analysis
Genomics. 2024 Mar 26:110837. doi: 10.1016/j.ygeno.2024.110837. Online ahead of print.ABSTRACTMangroves are an important part of coastal and estuarine ecosystems where they serve as nurseries for marine species and prevent coastal erosion. Here we report the genome of Sonneratia ovata, which is a true mangrove that grows in estuarine environments and can tolerate moderate salt exposure. We sequenced the S. ovata genome and assembled it into chromosome-level scaffolds through the use of Hi-C. The genome is 212.3 Mb and contains 12 chromosomes that range in size from 12.2 to 23.2 Mb. Annotation identified 29,829 genes with a...
Source: Genomics - March 28, 2024 Category: Genetics & Stem Cells Authors: Jeremy R Shearman Chaiwat Naktang Chutima Sontirod Wasitthee Kongkachana Sonicha U Thoomporn Nukoon Jomchai Chatree Maknual Suchart Yamprasai Poonsri Wanthongchai Wirulda Pootakham Sithichoke Tangphatsornruang Source Type: research
Hypoxic environment promotes angiogenesis and bone bridge formation by activating Notch/RBPJ signaling pathway in HUVECs
Genomics. 2024 Mar 25;116(3):110838. doi: 10.1016/j.ygeno.2024.110838. Online ahead of print.ABSTRACTAfter epiphyseal fracture, the epiphyseal plate is prone to ischemia and hypoxia, leading to the formation of bone bridge and deformity. However, the exact mechanism controlling the bone bridge formation remains unclear. Notch/RBPJ signaling axis has been indicated to regulate angiogenesis and osteogenic differentiation. Our study aims to investigate the mechanism of bone bridge formation after epiphyseal plate injury, and to provide a theoretical basis for new therapeutic approaches to prevent the bone bridge formation. Th...
Source: Genomics - March 27, 2024 Category: Genetics & Stem Cells Authors: Wendong Liu Mincheng Zou Mimi Chen Zheng Zhang Yunpeng Mao Yuhao Yang Ya Liu Qin Shi Xiaodong Wang Fuyong Zhang Source Type: research
Study on the interaction protein of transcription factor Smad3 based on TurboID proximity labeling technology
Genomics. 2024 Mar 25:110839. doi: 10.1016/j.ygeno.2024.110839. Online ahead of print.ABSTRACTTurboID is a highly efficient biotin-labelling enzyme, which can be used to explore a number of new intercalating proteins due to the very transient binding and catalytic functions of many proteins. TGF-β/Smad3 signaling pathway is involved in many diseases, especially in diabetic nephropathy and inflammation. In this paper, a stably cell line transfected with Smad3 were constructed by using lentiviral infection. To further investigate the function of TGF-β/Smad3, the protein labeling experiment was conducted to find the interac...
Source: Genomics - March 27, 2024 Category: Genetics & Stem Cells Authors: Biao Yan Ting Zeng Xiaoshan Liu Yuanyuan Guo Hongguang Chen Shuang Guo Wu Liu Source Type: research
