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Total 1432 results found since Jan 2013.
MiR-767-3p promotes the progression of hepatocellular carcinoma via targeting CASP-3/-9
CONCLUSION: MiR-767-3p promoted proliferation and prevented apoptosis in human hepatocellular carcinoma (HCC) through inhibiting the caspase-3/caspase-9 pathway.PMID:37193190 | PMC:PMC10182511
Source: American Journal of Translational Research - May 16, 2023 Category: Research Authors: Maolin Wu Jing Deng Dejiao Yao Shijie Li Source Type: research
GSE150260 FTO regulated genes in Hepatocellular Carcinoma
Contributor : Shen YinghaoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the global genes regulated by FTO high-throughput mRNA sequencing (RNA-Seq) was performed to compare the expression profile between HepG2 cells transfected with control siRNA or FTO siRNA.
Source: GEO: Gene Expression Omnibus - May 10, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Blocking autophagy by the two-pore channels antagonist tetrandrine improves sorafenib-induced death of hepatocellular carcinoma cells
Toxicol In Vitro. 2023 Apr 28:105603. doi: 10.1016/j.tiv.2023.105603. Online ahead of print.ABSTRACTSorafenib, an oral multi-kinase inhibitor, used to treat hepatocellular carcinoma (HCC). However, drug resistance is still common in several HCC patients. This complex mechanism is not yet fully elucidated, driving the search for new therapeutic targets to potentiate the antitumoral effect of sorafenib. Recent findings have linked the expression of Two-Pore Channels (TPCs) receptors with the development and progression of cancer. TPCs receptors are stimulated by NAADP, a Ca2+ messenger, and inhibited by their antagonists Ned...
Source: Toxicology in Vitro - April 30, 2023 Category: Toxicology Authors: Let ícia Paulino Sperandio Isis Valeska F Lins Adolfo G Erustes Anderson H F F Le ão Fernanda Antunes Ingrid B M Morais Heron Fernandes Vieira La ís Maria de Campos Claudia Bincoletto Soraya S Smaili Gustavo J S Pereira Source Type: research
Comprehensive Analysis of NABP2 as a Prognostic Biomarker and Its Correlation with Immune Infiltration in Hepatocellular Carcinoma
CONCLUSION: Based on these findings, NABP2 appears to be a candidate biomarker for HCC prognosis and immunotherapy.PMID:37113629 | PMC:PMC10128078 | DOI:10.2147/JIR.S403370
Source: Cell Research - April 28, 2023 Category: Cytology Authors: Bowen Li Jinghang Liu Liangzhi Xu Qi Xu Zhaohui Liu Tiande Liu Source Type: research
Knockdown of LPCAT1 Repressed Hepatocellular Carcinoma Growth and Invasion by Targeting S100A11
CONCLUSION: LPCAT1 promoted the growth, invasion and migration of HCC cells by regulating S100A11 and Snail. Therefore, LPCAT1 may serve as a potential molecular target for the diagnosis and treatment of HCC.PMID:37094849
Source: Annals of Clinical and Laboratory Science - April 24, 2023 Category: Laboratory Medicine Authors: Qigang Sun Cexiong Fu Jun Liu Shibing Li Jinfang Zheng Source Type: research
