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KLF6 Super-enhancer Regulates Cell Proliferation by Recruiting GATA2 and SOX10 in Human Hepatoma Cells
Mol Biol (Mosk). 2022 May-Jun;56(3):498-499. doi: 10.31857/S0026898422030144.ABSTRACTSuper-enhancer consists of a large cluster of transcription enhancers that regulates the expression of genes playing an important role in the growth and development of malignant tumors. Recently, several attempts for the identification of super-enhancers have been made, but their functional role in tumor cells remains unclear. This paper aims at elucidating the functional properties of KLF6 super-enhancer related to the growth regulation of HepG2 cells, in relation to transcription factors (TFs). First, some TFs specifying KLF6 super enhan...
Source: Molekuliarnaia Biologiia - May 27, 2022 Category: Molecular Biology Authors: Kum Chol Ri Myong Ryong Ri Kwang Hun Kim Sun Il Choe Ju Hua Ri Ji Hyon Kim Jong Ho Ri Source Type: research
