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What evidence for a cholera vaccine? Jaime Ferr án's submissions to the Prix Bréant
This article analyses how the French Academy of Sciences assessed Jaime Ferrán's cholera vaccine submitted for the Prix Bréant in the 1880s. Ferrán, a Spanish independent physician, discovered the treatment in 1884 and tried it on thousands of patients during the cholera outbreak in Valencia the following year. His evaluation sparked a controversy in Spain and abroad on the vaccine's efficacy. The Bréant jury did not see any evidence for it in Ferrán's submission, a decision usually interpreted in terms of French scientific nationalism (or simple chauvinism): an outsider from the scientific periphery could not be awar...
Source: Medical History - September 19, 2023 Category: History of Medicine Authors: Clara Uzcanga David Teira Source Type: research
Global Bibliometric Analysis of Leishmaniasis Literature for the Last 20 Years and Investigating the Contribution of T ürkiye
CONCLUSION: The number of publications, especially in endemic areas, was found to be limited other than Brazil. Studies in this area should be supported to ensure the eradication of the disease.PMID:37724362 | DOI:10.4274/tpd.galenos.2023.76376
Source: Turkish Society for Parasitology - September 19, 2023 Category: Parasitology Authors: Sevil Alkan O ğuz Evlice Mustafa Serhat Şahinoğlu Source Type: research
What evidence for a cholera vaccine? Jaime Ferr án's submissions to the Prix Bréant
This article analyses how the French Academy of Sciences assessed Jaime Ferrán's cholera vaccine submitted for the Prix Bréant in the 1880s. Ferrán, a Spanish independent physician, discovered the treatment in 1884 and tried it on thousands of patients during the cholera outbreak in Valencia the following year. His evaluation sparked a controversy in Spain and abroad on the vaccine's efficacy. The Bréant jury did not see any evidence for it in Ferrán's submission, a decision usually interpreted in terms of French scientific nationalism (or simple chauvinism): an outsider from the scientific periphery could not be awar...
Source: Medical History - September 19, 2023 Category: History of Medicine Authors: Clara Uzcanga David Teira Source Type: research
Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications and CBT4CBT: protocol for a randomized clinical trial in a diverse patient population
CONCLUSIONS: Project ENHANCE is expected to generate novel findings to inform future hospital-based efforts to promote AUD treatment engagement among diverse patient populations, including those most impacted by AUD.CLINICAL TRIAL REGISTRATION: Clinicaltrials.gov identifier: NCT05338151.PMID:37726823 | PMC:PMC10510167 | DOI:10.1186/s13722-023-00407-9
Source: Addiction Science and Clinical Practice - September 19, 2023 Category: Addiction Authors: E Jennifer Edelman Oscar F Rojas-Perez Charla Nich Joanne Corvino Tami Frankforter Derrick Gordon Ayana Jordan Manuel Paris Melissa B Weimer Brian T Yates Emily C Williams Brian D Kiluk Source Type: research
Women's experiences of primary dysmenorrhea symptoms: a systematic review of qualitative evidence and meta-aggregation
Women Health. 2023 Sep 14;63(8):658-668. doi: 10.1080/03630242.2023.2255289. Epub 2023 Sep 19.ABSTRACTPrimary dysmenorrhea (PD) has a significant impact on women's lives, especially among young women who miss school and work due to painful periods. Experiences and how women manage PD have been explored to some extent, but the evidence has not been systematically collated and reviewed to allow health professionals to better understand women's experiences of and perceptions about PD. Hence, we aim to synthesize the qualitative evidence related to women's experiences of PD and associated symptoms. For this purpose, seven data...
Source: Women and Health - September 19, 2023 Category: Primary Care Authors: Ana Moreno G ómez Ping Guo Ana Isabel de la Llave Rinc ón Nikolaos Efstathiou Source Type: research
Minutes of the Annual Business Meeting of the Members of the Behavior Genetics Association : June 24, 2023, 12:15-13:30, Venue 'Auditorium and Conference Centre' Murcia (Spain)
Behav Genet. 2023 Sep 19. doi: 10.1007/s10519-023-10157-8. Online ahead of print.NO ABSTRACTPMID:37723379 | DOI:10.1007/s10519-023-10157-8
Source: Behavior Genetics - September 18, 2023 Category: Genetics & Stem Cells Source Type: research
Awards Presented at the 53rd Annual Meeting of the Behavior Genetics Association, June 24 2023, Murcia, Spain
Behav Genet. 2023 Sep 19. doi: 10.1007/s10519-023-10158-7. Online ahead of print.NO ABSTRACTPMID:37723378 | DOI:10.1007/s10519-023-10158-7
Source: Behavior Genetics - September 18, 2023 Category: Genetics & Stem Cells Source Type: research
Genotyping of the rs1800440 Polymorphism in CYP1B1 Gene and the rs9258883 Polymorphism in HLA-B Gene in a Spanish Cohort of 223 Patients with Frontal Fibrosing Alopecia
Acta Derm Venereol. 2023 Sep 18;103:adv9604. doi: 10.2340/actadv.v103.9604.ABSTRACTThe pathogenesis of frontal fibrosing alopecia has been linked to specific genetic variants. CYP1B1 codes for a component of the cytochrome p450 machinery that is involved in the metabolism of xenobiotic oestrogens. The study of the prevalence of polymorphisms in this gene may help to understand their role in the development of frontal fibrosing alopecia. The aim of this study is to describe the frequency of genetic variations in the alleles HLA-B*07:02 and CYP1B1 in patients with frontal fibrosing alopecia. A cross-sectional study was desig...
Source: Acta Dermato-Venereologica - September 18, 2023 Category: Dermatology Authors: David Saceda-Corralo Daniel Ortega-Quijano Gloria Mu ñoz-Martín Óscar M Moreno-Arrones Cristina Pindado-Ortega Tuntas Rayinda Ana Meli án-Olivera Carlos Azc árraga-Llobet Patricia Burgos-Blasco Mar ía Elena Castañeda-Bermúdez Francisco J Del Casti Source Type: research
Highlights 56th SEPAR Congress
Open Respir Arch. 2023 Sep 1;5(3):100265. doi: 10.1016/j.opresp.2023.100265. eCollection 2023 Jul-Sep.ABSTRACTThe Spanish Society of Pneumology and Thoracic Surgery (SEPAR) has held its 56th congress in Granada from 8 to 10 June 2023. The SEPAR congress has established itself as the leading scientific meeting for specialists in medicine and respiratory care, reaching a record of participation this year with 2600 attendees. Our society thus demonstrates its leadership in the management of respiratory diseases, as well as its growth and progress in order to achieve excellence. In this review, we offer a summary of some notab...
Source: Respiratory Care - September 18, 2023 Category: Respiratory Medicine Authors: Pablo S ánchez-Salcedo Ana Bel én Llanos-González Sandra Dorado Arenas Noelia Carri ón Collado Agust ín Roberto García Marta S ánchez Zaballos Tamara Alonso P érez Source Type: research
Prevalence of mutations associated with macrolide and fluoroquinolone resistance in Neisseria gonorrhoeae with Allplex NG-DR Assay (Seegene) in a tertiary hospital from Madrid, Spain
CONCLUSIONS: We report a low-prevalence of mutations A2059G/C2611T to macrolides and a high-prevalence to S91F in NG infections. Molecular methods for the detection of NG resistance could be useful in direct non-culturable samples.PMID:37721708 | DOI:10.37201/req/058.2023
Source: Revista Espanola de Quimioterapia - September 18, 2023 Category: Drugs & Pharmacology Authors: A Maldonado-Barrueco C Sanz-Gonz ález I Falces-Romero P Garc ía-Clemente J Cacho-Calvo I Quiles-Melero Source Type: research
Bacillus Calmette-Gu érin vaccination for protection against recurrent herpes labialis: a nested randomised controlled trial
EClinicalMedicine. 2023 Sep 11;64:102203. doi: 10.1016/j.eclinm.2023.102203. eCollection 2023 Oct.ABSTRACTBACKGROUND: Recurrences of herpes simplex virus (HSV) in the orofacial region (herpes labialis or cold sores) impact quality-of-life. We aimed to study whether the bacille Calmette-Guérin (BCG) vaccine can attenuate cold sore recurrences through off-target immunomodulatory effects.METHODS: In this nested randomised controlled trial within the multicentre, phase 3 BRACE trial, 6828 healthcare workers were randomised in 36 sites in Australia, the Netherlands, Spain, the United Kingdom and Brazil, to receive BCG-Denmark ...
Source: Herpes - September 18, 2023 Category: Infectious Diseases Authors: Laure F Pittet Cecilia L Moore Ellie McDonald Simone Barry Marc Bonten John Campbell Julio Croda Margareth Dalcolmo Andrew Davidson Mark W Douglas Kaya Gardiner Amanda Gwee Bruno Jardim Marcus V G Lacerda Michaela Lucas David J Lynn Laurens Manning Robert Source Type: research
Personal exposure to radiofrequency electromagnetic fields in various occupations in Spain and France
CONCLUSION: We conducted personal RF-EMF measurements among workers in various occupations in Spain and France. Overall, RF-EMF exposure ≥1 % ICNIRP was infrequent, despite some intermittent exposures ≥100% observed among workers in some occupations.PMID:37722304 | DOI:10.1016/j.envint.2023.108156
Source: Environment International - September 18, 2023 Category: Environmental Health Authors: Maxime Turuban Hans Kromhout Javier Vila Miquel Vallbona-Vist ós Isabelle Baldi Michelle C Turner Source Type: research
Mobility of antimony in contrasting surface environments of a mine site: influence of redox conditions and microbial communities
Environ Sci Pollut Res Int. 2023 Sep 18. doi: 10.1007/s11356-023-29734-9. Online ahead of print.ABSTRACTMicrobial processes can influence the complex geochemical behaviour of the toxic metalloid antimony (Sb) in mining environments. The present study is aimed to evaluate the influence of microbial communities on the mobility of Sb from solid phases to water in different compartments and redox conditions of a mining site in southwest (SW) Spain. Samples of surface materials presenting high Sb concentrations, from two weathered mining waste dumps, and an aquatic sediment were incubated in slurries comparing oxic and anoxic c...
Source: Environmental Science and Pollution Research International - September 18, 2023 Category: Environmental Health Authors: Jes ús Daniel Peco Hugues Thouin Jos é María Esbrí H éctor Ricardo Campos-Rodríguez Eva Maria Garc ía-Noguero Dominique Breeze Jaime Villena Eric Gloaguen Pablo Leon Higueras Fabienne Battaglia-Brunet Source Type: research
