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This page shows you the latest news items in this category. This is page number 4.

Lupus a Tough Disease to Spot, Treat
MONDAY, May 30, 2016 -- Lupus is difficult to diagnose and treat, but scientists are working to learn more about its genetic causes and to develop better treatments. The autoimmune disease affects between 300,000 and 1.5 million people in the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 30, 2016 Category: Journals (General) Source Type: news

Lupus patients 'at higher risk of developing other health conditions'
People with lupus are at a greater risk of developing other health conditions than members of the general population.This is according to a new study conducted by the University of Nottingham and the Arthritis Research UK Primary Care Centre at Keele University, which examined the frequency of comorbidities associated with systemic lupus erythematosus in the UK between 1999 and 2012.A broad UK study Published in the medical journal Arthritis Care & Research, the study drew upon data from the UK Clinical Practice Research Datalink, identifying cases of lupus and matching each one by age, gender and practice to four heal...
Source: Arthritis Research UK - May 27, 2016 Category: Rheumatology Source Type: news

[Editors' Choice] Lupus: subdivide in order to conquer?
Author: Paula A. Kiberstis (Source: ScienceNOW)
Source: ScienceNOW - May 27, 2016 Category: Science Authors: Paula A. Kiberstis Tags: Autoimmune Disease Source Type: news

Antiaging Yoga
by guest blogger Holly Walck Kostura, BSN and certified Iyengar Yoga teacher To quote Webster's: "Aging (adj): (of a thing) reaching the end of useful life; growing old or older, especially visibly and obviously so; obsolescent Obsolescent (adj): becoming obsolete Obsolete (adj): no longer produced or used; out-of-date." When I was 22 years old, a friend and I went into a local bookstore and saw a display of exercise videos, including one titled, Yoga for Beginners. The middle-aged woman demonstrating the pose on the cover looked strong, stable, flexible, and joyful, and I remember knowing that the way she looked WAS ...
Source: Healthy Living - The Huffington Post - May 20, 2016 Category: Consumer Health News Source Type: news

Charlotte’s story: Overcoming lupus
A few months ago, Bonnie Godas, a Braintree mother of two, called a friend at the Massachusetts Statehouse asking a simple question. That friend phoned a friend at the Massachusetts Department of Transportation. Several phones calls later, Bonnie heard the news. On May 21, Boston’s iconic Zakim Bridge will be lit purple in recognition of Lupus Awareness Month. “I’m excited. I’m grateful and thrilled that Charlotte is doing so well,” says Bonnie. “It’s so important for parents to know about lupus because it can mask itself as other conditions like fibromyalgia and rheumatoid arthritis.” Lupus is an unpredict...
Source: Thrive, Children's Hospital Boston - May 20, 2016 Category: Pediatrics Authors: Lisa Fratt Tags: Diseases & Conditions Teen Health Dr. Robert Sundel lupus rheumatology program Source Type: news

Lupus More Severe in Kids, Large Study Confirms (CME/CE)
(MedPage Today) -- Mortality much higher than in adults with SLE (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - May 16, 2016 Category: Pediatrics Source Type: news

Study lays groundwork for refractory cutaneous lupus treatment algorithms
SCOTTSDALE, ARIZ. – Thalidomide, methotrexate, dapsone, and belimumab may be the best treatment alternatives for cutaneous lupus erythematosus that is refractory to antimalarials, based on reviews of 15 years of medical records from three large tertiary care centers. The study is the largest so... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 13, 2016 Category: Dermatology Source Type: news

NICE approves GSK's lupus drug Benlysta
The National Institute for Health and Care Excellence (NICE) has reportedly approved GlaxoSmithKline's (GSK) Benlysta for the treatment of lupus. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - May 12, 2016 Category: Pharmaceuticals Source Type: news

Nigeria: Save Okpokwu From Chronic Kidney Disease
[Guardian] Like every other young married lady, Mrs. Jacinta Okpokwu had her own plans about the future, but terminal sickness is at the verge of changing it. The 28-year-old lady, who hails from Aku in Igbo-Etiti Local Council of Enugu State, is battling to stay alive because of acute chronic kidney disease and Systemic Lupus Erythermatosus (SLE) attack. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 11, 2016 Category: African Health Source Type: news

UK cost body finally approves limited use of GSK's lupus drug
LONDON (Reuters) - Britain's healthcare cost watchdog has finally approved GlaxoSmithKline's lupus drug Benlysta for limited use, after rejecting it since 2011 on the grounds that it failed to offer good value for money. (Source: Reuters: Health)
Source: Reuters: Health - May 10, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

In the Loop: Curling for a Cause: 'Lupus 'Spiel USA' Raises Funds for Research
This story originally appeared on the In the Loop blog. _________________________________________________ Regan Birr was diagnosed with lupus when she was 21 years old. In the years since, she tells us her road to recovery has been a long and winding one. "When I first got sick, I had extreme pain and fatigue all over my body," she says. [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - May 10, 2016 Category: Databases & Libraries Source Type: news

Lupus Awareness Month: Shining Light on a Dark Disease
'Some patients will live their life on a nonstop roller-coaster ride of being abled and disabled, in a flare and in remission.' (Source: U.S. News - Health)
Source: U.S. News - Health - May 9, 2016 Category: Consumer Health News Authors: Marisa Zeppieri-Caruana Source Type: news

Association Between Diet and Glucocorticoid Treatment in SLEAssociation Between Diet and Glucocorticoid Treatment in SLE
Can the risk for and severity of systemic lupus erythematosus be modified by diet? Lupus Science & Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 6, 2016 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Antibody targets and destroys cells implicated in systemic lupus erythmatosis
(Journal of Clinical Investigation) In this issue of JCI Insight, research groups led by Ian Wicks of the University of Melbourne and Nicholas Wilson of CSL Limited developed an antibody (CSL362) directed against the surface molecule CD123 that targets and depletes pDCs and other cells implicated in SLE. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 5, 2016 Category: Global & Universal Source Type: news

Listening to lupus
Lupus is a mysterious chronic illness that primarily affects women in their prime of life. In people with lupus, the immune system goes awry, attacking healthy tissue. While there is no cure, there are many options for treatment, including ones being studied at Yale School of Medicine. For May, lupus awareness month, YaleNews spoke to Dr. Lenore Buckley, professor of medicine in the Section of Rheumatology, who recently launched an innovative clinical program for patients with lupus. (Source: Yale Science and Health News)
Source: Yale Science and Health News - May 4, 2016 Category: Universities & Medical Training Tags: Yale News Source Type: news

Probiotic supplements 'could help prevent menopause-associated bone loss'
Bone loss associated with the menopause could potentially be addressed through the use of probiotic supplements.This is according to new research from the Emory University School of Medicine and Georgia State University in the US, which conducted an experiment with mice and discovered evidence that probiotic bacteria may have potential as an affordable treatment for postmenopausal osteoporosis.Encouraging results The study involved the use of mice that had had their ovaries removed, meaning the animals underwent the same hormonal changes that occur when women reach the menopause.It was shown that the resulting loss of oest...
Source: Arthritis Research UK - May 3, 2016 Category: Rheumatology Source Type: news

Can Artificial Intelligence Identify Your Next Heart Attack?
This study will be evaluating outcomes based on patients who are going for a coronary angiogram, the gold standard in identifying blockages in the coronary arteries. These AI algorithms will develop over time and can be further refined with more data. The hope is that these algorithms will eventually lead to developing a lexicon that can help identify cardiovascular disease in women and men based on how they describe their symptoms. From a medical standpoint, the implications of using linguistic AI algorithms are substantial. When calling 911 for help, based on how and what someone says, these AI algorithms may identify s...
Source: Science - The Huffington Post - April 29, 2016 Category: Science Source Type: news

New studies published in Nature Immunology further understanding of immune system
(MedImmune, Inc.) MedImmune, the global biologics research and development arm of AstraZeneca, today announced that it has achieved a significant scientific milestone by publishing three manuscripts in Nature Immunology that advance the understanding of the immune system and highlight underlying mechanisms in two little-understood disease areas -- chronic obstructive pulmonary disease (COPD) and systemic lupus erythematosus (SLE). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 25, 2016 Category: Global & Universal Source Type: news

Defects in body's cell disposal system may contribute to the most common form of lupus
Scientists may be setting the stage for new approaches to control or prevent the inflammation and tissue damage associated with the chronic autoimmune disorder lupus. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 20, 2016 Category: Science Source Type: news

Kidney Lesions Predict Poor Outcomes in Lupus (CME/CE)
(MedPage Today) -- The presence of more crescents presaged ESRD, death (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 20, 2016 Category: Primary Care Source Type: news

Role for oxidized mitochondrial DNA in lupus revealed
The neutrophils of systemic lupus erythematosus patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response, researchers have discovered. The study suggests that targeting the pathways that lead to the accumulation of this DNA and/or facilitate its removal could be new ways to treat this chronic autoimmune disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 18, 2016 Category: Science Source Type: news

Baylor study reveals role for oxidized mitochondrial DNA in lupus
(Rockefeller University Press) Researchers at the Baylor Institute for Immunology Research have discovered that the neutrophils of systemic lupus erythematosus patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response. The study, which will be published online April 18 in The Journal of Experimental Medicine, suggests that targeting the pathways that lead to the accumulation of this DNA and/or facilitate its removal could be new ways to treat this chronic autoimmune disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 18, 2016 Category: Global & Universal Source Type: news

Well: Ask Well: Why Is Arthritis More Common in Women Than Men?
More women than men get arthritis over all, but there are many types of arthritis, and some types are more common in men. (Source: NYT Health)
Source: NYT Health - April 14, 2016 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Arthritis Autoimmune Diseases Lupus Erythematosus Osteoarthritis Rheumatoid Arthritis Women and Girls Aging Ask Well Featured Live Source Type: news

UCLA research suggests that gut bacteria could help prevent cancer
Researchers have shown that various types of intestinal bacteria might be factors in both causing and preventing obesity, and in other conditions and diseases. Now, a UCLA study suggests that it could also potentially be used to reduce the risk for some types of cancer. The research, published online April 13 in the peer-reviewed journal PLOS ONE, offers evidence that anti-inflammatory “health beneficial” gut bacteria can slow or stop the development of some types of cancer. Ultimately, doctors might be able to reduce a person’s risk for cancer by analyzing the levels and types of intestinal bacteria in the body, a...
Source: UCLA Newsroom: Health Sciences - April 13, 2016 Category: Universities & Medical Training Source Type: news

CV Events Strike Early in Lupus (CME/CE)
(MedPage Today) -- Myocardial infarctions can occur even before lupus is diagnosed (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 13, 2016 Category: Primary Care Source Type: news

Cutaneous Lupus Erythematosus: An UpdateCutaneous Lupus Erythematosus: An Update
What is the current understanding regarding the immunopathogenesis of cutaneous lupus erythematosus? Read about the latest efforts to define CLE, as well as available treatments, in this update. American Journal of Clinical Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 13, 2016 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

Fertility treatments may impact on breast cancer risk
Infertility and hormonal fertility treatments appear to increase density of breast tissue Related items from OnMedicaNHS must stop restricting IVF treatment, NICE saysPersonalised test could fine tune IVF treatmentCo-morbidities prove large risk factor for maternal deathsBlood test identifies high-risk lupus pregnancies (Source: OnMedica Latest News)
Source: OnMedica Latest News - April 13, 2016 Category: UK Health Source Type: news

Well: Ask Well: Why Is Arthritis More Common in Women Than Men?
More women than men get arthritis over all, but there are many types of arthritis, and some types are more common in men. (Source: NYT)
Source: NYT - April 12, 2016 Category: American Health Authors: RONI CARYN RABIN Tags: Ask Well Arthritis Rheumatoid Arthritis Autoimmune Diseases Lupus Erythematosus Women and Girls Live Featured Aging Osteoarthritis Source Type: news

Well: Ask Well: Why Is Arthritis More Common in Women Than Men?
More women than men get arthritis over all, but there are many types of arthritis, and some types are more common in men. (Source: NYT Health)
Source: NYT Health - April 12, 2016 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Ask Well Arthritis Rheumatoid Arthritis Autoimmune Diseases Lupus Erythematosus Women and Girls Live Featured Aging Osteoarthritis Source Type: news

Well: Ask Well: Why Is Arthritis More Common in Women Than Men?
More women than men get arthritis over all, but there are many types of arthritis, and some types are more common in men. (Source: NYT)
Source: NYT - April 12, 2016 Category: Nutrition Authors: RONI CARYN RABIN Tags: Ask Well Arthritis Rheumatoid Arthritis Autoimmune Diseases Lupus Erythematosus Women and Girls Live Featured Aging Osteoarthritis Source Type: news

Researchers find new clue in lupus autoantibody production
(Penn State) A signaling molecule called interferon gamma could hold the key to understanding how harmful autoantibodies form in lupus patients. The finding could lead to new treatments for the chronic autoimmune disease, said researchers at Penn State College of Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 12, 2016 Category: Global & Universal Source Type: news

CV Risks Up in Cutaneous Lupus (CME/CE)
(MedPage Today) -- Chance of cerebrovascular events three times higher versus controls (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 6, 2016 Category: Primary Care Source Type: news

Distinguishing SLE and Fibromyalgia by Complement ActivationDistinguishing SLE and Fibromyalgia by Complement Activation
Read how testing for cell-bound complement activation products can help establish an accurate diagnosis for SLE. Lupus Science & Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 6, 2016 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Are Lupus & Bipolar Disorder Related?
Nervous system problems caused by Lupus and SLE parallel those of bipolar disorder and may be treated the same, but do not indicate a diagnosis of bipolar. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - April 2, 2016 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Cutaneous lupus may raise risk of stroke, TIA
The higher risk of cardiovascular morbidity and mortality that has been repeatedly observed among patients with systemic lupus erythematosus (SLE) may extend only to stroke and transient ischemic attack among patients with disease limited to the skin and not to ischemic heart disease, heart... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 31, 2016 Category: Dermatology Source Type: news

Cutaneous lupus may raise risk of stroke, TIA
The higher risk of cardiovascular morbidity and mortality that has been repeatedly observed among patients with systemic lupus erythematosus (SLE) may extend only to stroke and transient ischemic... (Source: Clinical Neurology News)
Source: Clinical Neurology News - March 31, 2016 Category: Neurology Source Type: news

Orencia: Try Again in Lupus? (CME/CE)
(MedPage Today) -- Benefits seen for articular symptoms (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 31, 2016 Category: Primary Care Source Type: news

Great American Smokeout Stands Out Among 'Awareness Days'
THURSDAY, March 31, 2016 -- Health-focused awareness days dot the calendar each year. There's World Health Day, World Dolphin Day, World Lupus Day and hundreds more. Whether they actually boost action on specific health issues isn't clear,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 31, 2016 Category: Journals (General) Source Type: news

Kirsty Keep who begged to go to Dignitas told chemo may have been wrong
Kirsty Keep, 23, of Maidstone, Kent, was diagnosed with lupus and treated with chemotherapy. But doctors now say she may have a genetic skin and bone disorder instead. (Source: the Mail online | Health)
Source: the Mail online | Health - March 30, 2016 Category: Consumer Health News Source Type: news

An Open Letter to the Boston Globe About Lyme Disease
Today, the Boston Globe editorial board spoke out against a bill "that would require insurers in Massachusetts to cover Lyme disease treatments for as long as a doctor says they're needed." The Globe writes: Lawmakers may have good intentions, but they don't possess the expertise to decide whether it's beneficial, cost-efficient, or safe, to keep using strong medicines to treat a condition the medical establishment doubts is real. Such questions should be resolved by a consensus of doctors and researchers -- and buttressed by convincing clinical date [sic] -- not determined by legislative mandate. Who among the Boston Glob...
Source: Healthy Living - The Huffington Post - March 28, 2016 Category: Consumer Health News Source Type: news

Benlysta Found Steroid-Sparing in Lupus (CME/CE)
(MedPage Today) -- Modest effects in prednisone dose reduction seen in post-hoc analyses (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 26, 2016 Category: Primary Care Source Type: news

Targeting Interferon Shows Promise in Lupus (CME/CE)
(MedPage Today) -- Sifalimumab effective in a phase IIb trial, particularly for skin manifestations (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 25, 2016 Category: Rheumatology Source Type: news

Lupus patients’ transition to adult care leaves gaps, delays in care
Patients with childhood-onset systemic lupus erythematosus (SLE) who transitioned to adult care without a formal transitioning process had long periods without care despite having moderate disease... (Source: Pediatric News)
Source: Pediatric News - March 25, 2016 Category: Journals (General) Source Type: news

Claims that man flu 'really exists' are unsupported
Conclusion This small laboratory study points to specific biological mechanisms that might explain why women are more likely to suffer autoimmune disorders, such as SLE, than men. It found the second silenced copy of the X chromosome in women can be partially reactivated and express immune-related genes, instead of staying completely silent. Though this is a plausible reason for the overactive immune system found in SLE, it does not explain why men can also have the condition. Also, only SLE was investigated in this study and with blood samples from just five children with the condition. It is not clear at this stage how...
Source: NHS News Feed - March 23, 2016 Category: Consumer Health News Tags: Lifestyle/exercise Medical practice Source Type: news

Regulatory B Cell Processes Appear Aberrant in LupusRegulatory B Cell Processes Appear Aberrant in Lupus
Disruption of the processes that govern the differentiation of immature B cells into regulatory B cells (Bregs) that restrain inflammation may contribute to the pathogenesis of systemic lupus erythematosus (SLE). Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 22, 2016 Category: Pathology Tags: Rheumatology News Source Type: news

Penn vet study identifies mechanism explaining female bias in autoimmunity
(University of Pennsylvania) Possessing two X chromosomes is a double-edged sword, immunologically speaking. Females are better at fighting off infection than males, but they are also more susceptible to many autoimmune conditions, such as lupus. A new study published in Proceedings of the National Academy of Sciences and led by researchers from the University of Pennsylvania now offers the first mechanistic explanation for why this is the case. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 21, 2016 Category: Global & Universal Source Type: news

Getting a leg up on bone comorbidities in lupus
MAUI, HAWAII – Patients with systemic lupus erythematosus (SLE) really need to be placed on bone protection therapy as soon as they start on corticosteroids because their risks of steroid-related... (Source: Clinical Endocrinology News)
Source: Clinical Endocrinology News - March 19, 2016 Category: Endocrinology Source Type: news

Precision medicine's potential to define the genetics of autoimmune disease
Demonstrating the potential of precision medicine, an international study used next-generation DNA sequencing technology to identify more than 1,000 gene variants that affect susceptibility to systemic lupus erythematosus (SLE). (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 18, 2016 Category: Science Source Type: news

Study shows precision medicine's potential to define the genetics of autoimmune disease
(UT Southwestern Medical Center) Demonstrating the potential of precision medicine, an international study based at UT Southwestern Medical Center used next-generation DNA sequencing technology to identify more than 1,000 gene variants that affect susceptibility to systemic lupus erythematosus (SLE). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 18, 2016 Category: Global & Universal Source Type: news

Healthy IVF Egg Produces Offspring With LupusHealthy IVF Egg Produces Offspring With Lupus
Neonatal lupus can develop even when the newborn has not inherited a genetic susceptibility to autoimmunity from the mother, California-based researchers report. Reuters Health Information (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - March 17, 2016 Category: Dermatology Tags: Dermatology News Source Type: news