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Total 11587 results found since Jan 2013.
Preoperative treatment with mFOLFIRINOX or Gemcitabine/Nab-paclitaxel +/- isotoxic high-dose stereotactic body Radiation Therapy (iHD-SBRT) for borderline resectable pancreatic adenocarcinoma (the STEREOPAC trial): study protocol for a randomised comparative multicenter phase II trial
DISCUSSION: This trial will help define the best neoadjuvant treatment sequence for borderline resectable PDAC and aims to evaluate if a total neoadjuvant treatment integrating iHD-SBRT improves the patients' oncological outcomes.TRIAL REGISTRATION: The study was registered at ClinicalTrails.gov (NCT05083247) on October 19th, 2021, and in the Clinical Trials Information System (CTIS) EU CT database (2022-501181-22-01) on July 2022.PMID:37735634 | DOI:10.1186/s12885-023-11327-x
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Christelle Bouchart Julie Navez Ivan Borbath Karen Geboes Timon Vandamme Jean Closset Luigi Moretti Pieter Demetter Marianne Paesmans Jean-Luc Van Laethem Source Type: research
Stereotactic Body Radiation Therapy and Abiraterone Acetate for Patients Affected by Oligometastatic Castrate-Resistant Prostate Cancer: A Randomized Phase II Trial (ARTO)
CONCLUSION: The trial reached its primary end point of biochemical control and PFS, suggesting a clinical advantage for SBRT in addition to first-line AAP treatment in patients with metastatic castration-resistant prostate cancer.PMID:37733977 | DOI:10.1200/JCO.23.00985
Source: Clinical Prostate Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Giulio Francolini Andrea Gaetano Allegra Beatrice Detti Vanessa Di Cataldo Saverio Caini Alessio Bruni Gianluca Ingrosso Rolando Maria D'Angelillo Anna Rita Alitto Matteo Augugliaro Luca Triggiani Silvana Parisi Gaetano Facchini Marco Banini Gabriele Simo Source Type: research
Interprofessional Approach to Fall Risk Screening in Patients Undergoing Radiation Therapy
Clin J Oncol Nurs. 2023 Sep 15;27(5):565-570. doi: 10.1188/23.CJON.565-570.ABSTRACTPatients receiving radiation therapy (RT) for cancer are at greater risk for falls because of age, treatment, pharmacologic side effects, and cognitive or motor deficits. The Timed Up and Go (TUG) Test is a validated, objecti.PMID:37729459 | DOI:10.1188/23.CJON.565-570
Source: Clinical Journal of Oncology Nursing - September 20, 2023 Category: Nursing Authors: Amy Martinez Jason Baxley Emery Bergey Ron Jennings Cassandra Vonnes Source Type: research
Does radiation therapy affect adhesion of tricalcium silicate cements to root dentin?
CONCLUSION: The push-out bond strength of Biodentine and MTA to root canal dentin decreased significantly post irradiation.PMID:37729257 | DOI:10.1590/1678-7757-2023-0118
Source: Appl Human Sci - September 20, 2023 Category: Physiology Authors: Lochan Khullar Nidambur Vasudev Ballal Tan F ırat Eyüboğlu Mutlu Özcan Source Type: research
Association between immunohistochemical markers and tumor progression following resection of spinal chordomas: a multicenter study
CONCLUSIONS: These IHC variables with tree-based machine learning tools successfully demonstrate a high capacity to identify a patient's tumor progression pattern with an accuracy of 66%. Pancytokeratin, EMA, cytokeratin A1/A3, and S100 protein were the IHC drivers of a low tumor progression. This shows the power of machine learning algorithms in analyzing and predicting outcomes of rare conditions in a small sample size.PMID:37728388 | DOI:10.3171/2023.6.SPINE23348
Source: Journal of Neurosurgery.Spine - September 20, 2023 Category: Neurosurgery Authors: Abdul Karim Ghaith Oluwaseun O Akinduro Carlos Perez-Vega Antonio Bon Nieves Kingsley Abode-Iyamah Naresh Patel Maziyar Kalani Michelle J Clarke Peter Rose Mohamad Bydon Source Type: research
Does radiation therapy affect adhesion of tricalcium silicate cements to root dentin?
CONCLUSION: The push-out bond strength of Biodentine and MTA to root canal dentin decreased significantly post irradiation.PMID:37729257 | DOI:10.1590/1678-7757-2023-0118
Source: Appl Human Sci - September 20, 2023 Category: Physiology Authors: Lochan Khullar Nidambur Vasudev Ballal Tan F ırat Eyüboğlu Mutlu Özcan Source Type: research
Extraction of interoperable data from healthcare documents by identifying Common Data Elements: an analysis of Radiation Therapy Planning CT Physician Order Entry records
CONCLUSION: Structured and interoperable documentation of medical information can be achieved using common data elements. Our analysis showed that a lot of information recorded with healthcare documents can be presented with this approach. Yet, in the analyzed cohort of planning CT order entries, only a few common data elements were shared among the majority of documents. A common vocabulary and consensus upon relevant information is required to promote interoperability and standardization.PMID:37729894 | DOI:10.1159/000534204
Source: Oncology - September 20, 2023 Category: Cancer & Oncology Authors: Fabio Dennst ädt Paul Martin Putora Michael Heuser Eugenia Vlaskou Badra Brigitta Gertrud Baumert Dominic Leiser Nikola Cihoric Source Type: research
Analysis of Prognoses according to Breast MRI Results in Patients with Axillary Lymph Node Metastases from an Unknown Primary Origin
CONCLUSION: The prognoses of MR-negative patients with ACUPax who received ALND and WBRT followed by chemotherapy were as good as those of patients with MRI-detected primary breast cancers.PMID:37727923 | DOI:10.3349/ymj.2023.0181
Source: Yonsei Medical Journal - September 20, 2023 Category: Universities & Medical Training Authors: E-Ryung Choi Ok Hee Woo Eun Young Ko Boo-Kyung Han Ji Soo Choi Eun Sook Ko Haejung Kim Myoung Kyoung Kim Jeong Eon Lee Source Type: research
Association between immunohistochemical markers and tumor progression following resection of spinal chordomas: a multicenter study
CONCLUSIONS: These IHC variables with tree-based machine learning tools successfully demonstrate a high capacity to identify a patient's tumor progression pattern with an accuracy of 66%. Pancytokeratin, EMA, cytokeratin A1/A3, and S100 protein were the IHC drivers of a low tumor progression. This shows the power of machine learning algorithms in analyzing and predicting outcomes of rare conditions in a small sample size.PMID:37728388 | DOI:10.3171/2023.6.SPINE23348
Source: Journal of Neurosurgery.Spine - September 20, 2023 Category: Neurosurgery Authors: Abdul Karim Ghaith Oluwaseun O Akinduro Carlos Perez-Vega Antonio Bon Nieves Kingsley Abode-Iyamah Naresh Patel Maziyar Kalani Michelle J Clarke Peter Rose Mohamad Bydon Source Type: research
Extraction of interoperable data from healthcare documents by identifying Common Data Elements: an analysis of Radiation Therapy Planning CT Physician Order Entry records
CONCLUSION: Structured and interoperable documentation of medical information can be achieved using common data elements. Our analysis showed that a lot of information recorded with healthcare documents can be presented with this approach. Yet, in the analyzed cohort of planning CT order entries, only a few common data elements were shared among the majority of documents. A common vocabulary and consensus upon relevant information is required to promote interoperability and standardization.PMID:37729894 | DOI:10.1159/000534204
Source: Oncology - September 20, 2023 Category: Cancer & Oncology Authors: Fabio Dennst ädt Paul Martin Putora Michael Heuser Eugenia Vlaskou Badra Brigitta Gertrud Baumert Dominic Leiser Nikola Cihoric Source Type: research
Dosimetry in Lu-177-DOTATATE peptide receptor radionuclide therapy: a systematic review
ConclusionAccording to the present dosimetric review,177Lu-DOTATATE PRRT appears to be a safe and reliable treatment option for advanced GEP-NETs. From the dosimetric point of view, kidneys are theoretically the major organs at risk in177Lu-DOTATATE treatment. The optimization of the number of treatment cycles beyond the prescribed limit of four and the maximum administered activity in each cycle must be determined by individual patient dosimetry in order to reduce the risk of organ toxicities whilst maximizing therapeutic efficacy.
Source: Clinical and Translational Imaging - September 20, 2023 Category: Radiology Source Type: research
Endometrial adenocarcinoma recurring in the lung: impact of molecular profile and role of local therapies on prognosis
CONCLUSION: Although few patients will benefit from local treatment (stereotactic body radiation therapy or resection) after a recurrence involving the lung, local therapies might be considered as an option in oligometastatic lung recurrences as they achieve high local control rates and better oncological outcomes than systemic treatment alone.PMID:37726197 | DOI:10.1136/ijgc-2023-004534
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Ana Luzarraga Aznar Vicente Bebia Carlos L ópez-Gil Alexandra Giraldo M P Montoya Ramona Verges Alberto Jauregui Josep Castellvi Assumpci ó Pérez-Benavente Eva Col ás Antonio Gil-Moreno Silvia Cabrera Source Type: research
Risk Modeling for Individualization of the FLAME Focal Boost Approach in External Beam Radiation Therapy for Patients With Localized Prostate Cancer
CONCLUSIONS: Our results suggest that GG 1 patients already show a low level of failure at a standard dose of 77 Gy, limiting the additional benefit of focal boosting. In contrast, patients with high-risk characteristics, especially GG 4 or 5, show a low 5-year DFS, while focal boosting might improve this substantially. This suggests that reaching a high focal boost dose may be particularly beneficial for these patients.PMID:37725026 | DOI:10.1016/j.ijrobp.2023.07.044
Source: Health Physics - September 19, 2023 Category: Physics Authors: Karol ína Menne Guricová Veerle Groen Floris Pos Evelyn Monninkhof Sjoerd G Elias Karin Haustermans Robert J Smeenk Jochem van der Voort van Zyp C édric Draulans Sofie Isebaert Petra J van Houdt Linda G W Kerkmeijer Uulke A van der Heide Source Type: research
Relationship between seminal vesicle displacement and distribution of hydrogel spacer within the perirectal space in prostate radiotherapy
In conclusion, SV cranial displacement was influenced by HS lateral distribution of ≥1.00 cm in the upper two slices. Therefore, when the sigmoid colon or small bowel is depressed in rectovesical excavation and SV needs to be included in the target volume, HS insertion should be performed carefully.PMID:37719041 | PMC:PMC10502802 | DOI:10.3892/mco.2023.2674
Source: Clinical Prostate Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Kenji Makita Yasushi Hamamoto Hiromitsu Kanzaki Kei Nagasaki Katsuyoshi Hashine Source Type: research
