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Total 11587 results found since Jan 2013.
Preliminary study on dosimetry characteristics of a novel cylindrical dose verification system
CONCLUSIONS: This novel ionization chamber array demonstrates good dosimetry characteristics and is suitable for clinical IMRT and VMAT plan verifications.PMID:37665789 | DOI:10.1002/acm2.14138
Source: Journal of Applied Clinical Medical Physics - September 4, 2023 Category: Physics Authors: Long He Jinhan Zhu Xuetao Wang Bailin Zhang Qiang Hu Lixin Chen Xiaowei Liu Source Type: research
Anti-SOX-1 Antibody-Positive Paraneoplastic Limbic Encephalitis Diagnosed During Small Cell Lung Cancer Treatment
We present a case of anti-Sry-like high mobility group box 1 (SOX-1) antibody-positive PNS diagnosed during the treatment of small-cell lung cancer (SCLC). A 65-year-old woman with a history of smoking and SCLC (T3N1M0) was hospitalized to receive chemo-radiation therapy. On day 14, the course was complicated by left mastitis associated with febrile neutropenia. Drainage was performed for the left mastitis, and cefepime was initiated. The fever subsided within a few days, but the patient became agitated accompanied by logorrhea. With the exception of mental status, her neurological examination was unremarkable. Due to mild...
Source: Herpes - September 4, 2023 Category: Infectious Diseases Authors: Toru Yoshino Ryuta Yamamoto Yoji Hoshina Tomohiko Ishimine Source Type: research
Development and clinical implementation of a digital system for risk assessments for radiation therapy
Z Med Phys. 2023 Sep 2:S0939-3889(23)00092-2. doi: 10.1016/j.zemedi.2023.08.003. Online ahead of print.ABSTRACTBefore introducing new treatment techniques, an investigation of hazards due to unintentional radiation exposures is a reasonable activity for proactively increasing patient safety. As dedicated software is scarce, we developed a tool for risk assessment to design a quality management program based on best practice methods, i.e., process mapping, failure modes and effects analysis and fault tree analysis. Implemented as a web database application, a single dataset was used to describe the treatment process and its...
Source: Zeitschrift fur Medizinische Physik - September 4, 2023 Category: Radiology Authors: Dominik Kornek David Menichelli J örg Leske Michael Hofmann David Antkiewicz Tobias Brandt Oliver J Ott Michael Lotter Marga Lang-Welzenbach Rainer Fietkau Christoph Bert Source Type: research
Anti-SOX-1 Antibody-Positive Paraneoplastic Limbic Encephalitis Diagnosed During Small Cell Lung Cancer Treatment
We present a case of anti-Sry-like high mobility group box 1 (SOX-1) antibody-positive PNS diagnosed during the treatment of small-cell lung cancer (SCLC). A 65-year-old woman with a history of smoking and SCLC (T3N1M0) was hospitalized to receive chemo-radiation therapy. On day 14, the course was complicated by left mastitis associated with febrile neutropenia. Drainage was performed for the left mastitis, and cefepime was initiated. The fever subsided within a few days, but the patient became agitated accompanied by logorrhea. With the exception of mental status, her neurological examination was unremarkable. Due to mild...
Source: Herpes - September 4, 2023 Category: Infectious Diseases Authors: Toru Yoshino Ryuta Yamamoto Yoji Hoshina Tomohiko Ishimine Source Type: research
Management Paradigm of Central Nervous System Metastases in NSCLC: An Australian Perspective
JTO Clin Res Rep. 2023 Jul 26;4(9):100553. doi: 10.1016/j.jtocrr.2023.100553. eCollection 2023 Sep.ABSTRACTLife-prolonging central nervous system active systemic therapies for metastatic NSCLC have increased the complexity of managing brain metastases (BMs). Australian medical oncologists, radiation oncologists, and neurosurgeons discussed the evidence guiding the diverse clinical approaches to the management of BM in NSCLC. The Australian context is broadly applicable to other jurisdictions; therefore, we have documented these discussions as principles with broader applications. Patient management was stratified according...
Source: Clinical Lung Cancer - September 4, 2023 Category: Cancer & Oncology Authors: Chee Khoon Lee Yu Yang Soon Rosalind L Jeffree Rohit Joshi Eng-Siew Koh Wei-Sen Lam Hien Le Zarnie Lwin Mark B Pinkham Shankar Siva Evan Ng Thomas John Source Type: research
Preliminary study on dosimetry characteristics of a novel cylindrical dose verification system
CONCLUSIONS: This novel ionization chamber array demonstrates good dosimetry characteristics and is suitable for clinical IMRT and VMAT plan verifications.PMID:37665789 | DOI:10.1002/acm2.14138
Source: Journal of Applied Clinical Medical Physics - September 4, 2023 Category: Physics Authors: Long He Jinhan Zhu Xuetao Wang Bailin Zhang Qiang Hu Lixin Chen Xiaowei Liu Source Type: research
Dosimetric Validation for Prospective Clinical Trial of GRID Collimator-Based Spatially Fractionated Radiation Therapy: Dose Metrics Consistency and Heterogeneous Pattern Reproducibility
CONCLUSION: GRID collimator based SFRT delivers a consistent heterogeneity dose distribution and high dose core density across bulky tumor plans. The inter-plan reproducibility and simplicity of GRID therapy may be useful for certain clinical indications and inter-institutional clinical trial design, and its heterogeneity metrics may help guide MLC-based SFRT planning to achieve similar or further optimized dose distributions.PMID:37660738 | DOI:10.1016/j.ijrobp.2023.08.061
Source: Physics in Medicine and Biology - September 3, 2023 Category: Physics Authors: Hualin Zhang Lijun Ma Andrew Lim Jason Ye Lauren Lukas Heng Li Nina A Mayr Eric Lin Chang Source Type: research
SpaceOAR hydrogel distribution and early complications in patients undergoing radiation therapy for prostate cancer
CONCLUSIONS: Transperineal hydrogel placement separates the prostate from the rectum with a symmetrical distribution in the majority of cases prior to radiation therapy with a low rate of rectal wall injection and immediate complications.ADVANCES IN KNOWLEDGE: SpaceOAR hydrogel can be safely injected into radiation naive patients with low or intermediate-risk organ-confined prostate cancer. The spacer separates the prostate from the rectum with a symmetrical distribution in the majority of cases prior to radiation therapy.PMID:37660394 | DOI:10.1259/bjr.20220947
Source: The British Journal of Radiology - September 3, 2023 Category: Radiology Authors: Andrew H Yates Jack W Power Philip J Dempsey Adam Agnew Brian D Murphy Richard Moore Mazen El Bassiouni Michelle M J McNicholas Source Type: research
Accounting for fractionation and heterogeneous dose distributions in the modelling of osteoradionecrosis in oropharyngeal carcinoma treatment
CONCLUSION: Risk models for ORN based on conventional DVH parameters cannot be directly applied to HF-SBRT fractionation schemes and dose distributions. However, after correcting for fractionation and non-uniform dose distributions using EUD, a single model can distinguish between ORN and non-ORN after conventionally fractionated radiotherapy and hypofractionated boost treatments.PMID:37659662 | DOI:10.1016/j.radonc.2023.109889
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 2, 2023 Category: Radiology Authors: Gerda M Verduijn Nienke D Sijtsema Yvette van Norden Wilma D Heemsbergen Hetty Mast Aniel Sewnaik Denzel Chin Sarah Baker Marta E Capala Aad van der Lugt Esther van Meerten Mischa S Hoogeman Steven F Petit Source Type: research
Primary tumor site for localized Merkel cell carcinoma drives different management strategies without impacting oncologic outcomes
CONCLUSIONS: Among patients with primary MCC who had RT as a component of their initial treatment strategy, anatomically-driven heterogeneous treatment approaches were associated with equally excellent locoregional disease control.PMID:37659660 | DOI:10.1016/j.radonc.2023.109892
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 2, 2023 Category: Radiology Authors: Samuel Cass Brandon Cope Andrew J Bishop Yi-Ju Chiang B Ashleigh Guadagnolo Ahsan Farooqi William Morrison Russell G Witt Riyad N H Seervai Adam S Garden Clifton D Fuller Ryan P Goepfert Merrick Ross Jeffrey E Gershenwald Michael Wong Phyu P Aung Emily Z Source Type: research
Need for standardization in the use of structures in the intensity-modulated radiation therapy planning of head and neck cancers, a GORTEC study
Conclusion Use of nsRS is frequent but heterogeneous and should be standardized further in line with ICRU initiatives in IMRT planning. Use of nsRS should be documented with respect to the need for nsRS from dose computation algorithms of treatment planning systems and IMRT machines in terms of modulation capacity and plan robustness.PMID:37659657 | DOI:10.1016/j.radonc.2023.109895
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 2, 2023 Category: Radiology Authors: Özgür Özer Hanaan Shafi David O'Reilly Cedric Loiseau Catherine Dejean Jean Bourhis Juliette Thariat Source Type: research
Primary tumor site for localized Merkel cell carcinoma drives different management strategies without impacting oncologic outcomes
CONCLUSIONS: Among patients with primary MCC who had RT as a component of their initial treatment strategy, anatomically-driven heterogeneous treatment approaches were associated with equally excellent locoregional disease control.PMID:37659660 | DOI:10.1016/j.radonc.2023.109892
Source: Cancer Control - September 2, 2023 Category: Cancer & Oncology Authors: Samuel Cass Brandon Cope Andrew J Bishop Yi-Ju Chiang B Ashleigh Guadagnolo Ahsan Farooqi William Morrison Russell G Witt Riyad N H Seervai Adam S Garden Clifton D Fuller Ryan P Goepfert Merrick Ross Jeffrey E Gershenwald Michael Wong Phyu P Aung Emily Z Source Type: research
Accounting for fractionation and heterogeneous dose distributions in the modelling of osteoradionecrosis in oropharyngeal carcinoma treatment
CONCLUSION: Risk models for ORN based on conventional DVH parameters cannot be directly applied to HF-SBRT fractionation schemes and dose distributions. However, after correcting for fractionation and non-uniform dose distributions using EUD, a single model can distinguish between ORN and non-ORN after conventionally fractionated radiotherapy and hypofractionated boost treatments.PMID:37659662 | DOI:10.1016/j.radonc.2023.109889
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 2, 2023 Category: Radiology Authors: Gerda M Verduijn Nienke D Sijtsema Yvette van Norden Wilma D Heemsbergen Hetty Mast Aniel Sewnaik Denzel Chin Sarah Baker Marta E Capala Aad van der Lugt Esther van Meerten Mischa S Hoogeman Steven F Petit Source Type: research
