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Total 83 results found since Jan 2013.

Fecal microbiota transplantation treatment for refractory ulcerative colitis with allergy to 5-aminosalicylic acid: A case report
Conclusion: The choice of treatment for refractory UC patients who are allergic to 5-ASA is relatively limited. In our case, we highlight the specific role of FMT for refractory UC with absence of 5-ASA through intestinal microbiota reconstruction.
Source: Medicine - May 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

On-demand intermittent beclomethasone is effective for mild asthma in Brazil
ConclusionClinicians might consider intermittent inhaled steroid therapy as a therapeutic regimen for mild persistent asthma.Trial registration The Portuguese and English versions of the study protocol were submitted, approved, and registered in the Brazilian Network Platform for Clinical Trials (http://www.ensaiosclinicos.gov.br) under the primary identifier number “RBR-3gbyhk”. This platform is part of the Primary Registries in the World Health Organization Registry Network, where the trial is registered under the following Universal Trial Number: 1111-1149-4774
Source: Clinical and Translational Allergy - March 5, 2018 Category: Allergy & Immunology Source Type: research

The Immunologic Paradoxes of IgG4-Related Disease
AbstractIgG4-related disease (IgG4-RD), which usually occurs in middle-aged and elderly men, is a newly recognized fibroinflammatory condition characterized by swelling and sclerosis of involved organs, increased IgG4-positive plasma cell infiltration in lesions, and elevated IgG4 concentration in serum. Despite growing interest in the research, the pathophysiological mechanism remains elusive. Most IgG4-RD patients respond well to steroid therapy initially, but recurrent and refractory cases are common, especially in advanced fibrotic stage. Recent studies have documented the heterogeneity of the B cell lineages, which su...
Source: Clinical Reviews in Allergy and Immunology - February 19, 2018 Category: Allergy & Immunology Source Type: research

Impact of flash glucose monitoring on hypoglycaemia in adults with type 1 diabetes managed with multiple daily injection therapy: a pre-specified subgroup analysis of the IMPACT randomised controlled trial
Conclusions/interpretationUse of flash glucose technology in type 1 diabetes controlled with MDI therapy significantly reduced time in hypoglycaemia without deterioration of HbA1c, and improved treatment satisfaction.Trial registration:ClinicalTrials.gov NCT02232698Funding:Abbott Diabetes Care, Witney, UK
Source: Diabetologia - February 7, 2018 Category: Endocrinology Source Type: research

Clinical, Endoscopic and Histopathological Characteristics of Pediatric Patients with Eosinophilic Digestives Diseases attending the Gastroenterology Department of the National Institute Of Pediatrics in Mexico City
The objective of this study was to describe the clinical and paraclinical profile of pediatris patients with EDD.
Source: Journal of Allergy and Clinical Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Amyra Ali Azamar Jacome, Josefina Monserrat Cazares Mendez, David Alejandro Mendoza Hernandez, Jose G. Huerta Lopez Source Type: research

The association of air pollutants and allergic and nonallergic rhinitis in chronic rhinosinusitis
ConclusionOur results suggest that small inhalant pollutants may contribute to nonallergic symptomatology in patients with and without nasal polyps. Regardless of allergy status, BC may play a role in CRS symptom severity.
Source: International Forum of Allergy and Rhinology - December 11, 2017 Category: Allergy & Immunology Authors: Leila J. Mady, Hannah L. Schwarzbach, John A. Moore, Robert M. Boudreau, Thomas M. Kaffenberger, Thomas J. Willson, Stella E. Lee Tags: ORIGINAL ARTICLE Source Type: research

Idiopathic nephrotic syndrome.
Abstract Nephrotic syndrome (NS) is defined by massive proteinuria and hypoalbuminemia, with resulting hyperlipidemia and edema. The most common cause of NS in children is idiopathic nephrotic syndrome (INS), also called nephrosis. Its annual incidence has been estimated to 1-4 per 100,000 children and varies with age, race, and geography. Many agents or conditions have been reported to be associated with INS such as infectious diseases, drugs, allergy, vaccinations, and malignancies. The disease may occur during the 1st year of life, but it usually starts between the ages of 2 and 7 years. INS is characteriz...
Source: Archives de Pediatrie - November 20, 2017 Category: Pediatrics Authors: Boyer O, Baudouin V, Bérard E, Dossier C, Audard V, Guigonis V, Vrillon I Tags: Arch Pediatr Source Type: research

P241 Anti-IL5 monoclonal antibodies may provide benefit in asthmatics on chronic oral steroid therapy masking eosinophilia
Current guidelines for the use of anti-IL5 monoclonal antibodies in asthmatics require specified eosinophil counts in the peripheral blood (CBC). Absent eosinophilia in asthmatics on chronic steroid therapy may mask eosinophilic asthma and may not correlate with eosinophils in bronchial fluids and lung tissues.
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: R. Tamayev, S. Gupta, A. Rubinstein Source Type: research

Inflammatory Bowel Disease in Chronic Granulomatous Disease: an emerging problem over a twenty years ’ experience
ConclusionsPenetrance of CGD‐IBD increases with age. Clinical manifestations may be subtle, and clinicians should have a low threshold to recommend endoscopy. Treatment with NSAIDs and/or steroids achieves a good response, but relapses usually occur. Infection surveillance is mandatory during treatment, in order to prevent opportunistic infections. A close collaboration between Immunologists and Gastroenterologists is pivotal, including combined follow‐up.This article is protected by copyright. All rights reserved.
Source: Pediatric Allergy and Immunology - October 5, 2017 Category: Allergy & Immunology Authors: Giulia Angelino, Paola De Angelis, Simona Faraci, Francesca Rea, Erminia Francesca Romeo, Filippo Torroni, Renato Tambucci, Alessia Claps, Paola Francalanci, Maria Chiriaco, Gigliola Di Matteo, Caterina Cancrini, Paolo Palma, Patrizia D'Argenio, Luigi Dal Tags: Original Source Type: research

High-dose nebulized budesonide is effective for mild asthma exacerbations in children under 3 years of age.
Conclusion. For children < 3 years old with mild asthma exacerbations, high-dose nebulized budesonide therapy is equally as effective as systemic steroid therapy. PMID: 28120603 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - January 27, 2017 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Serum zinc level in bronchial asthma
Conclusion Measurement of zinc level could be recommended in asthmatic adults. proper supplementations of zinc can be useful in the management of asthmatic patients due to increase the effect of antioxidant defense system. However, further multi-centre studies with greater number of patients are needed to warrant the results of this study.
Source: Egyptian Journal of Chest Diseases and Tuberculosis - December 15, 2016 Category: Respiratory Medicine Source Type: research

Monitoring the hospital management of acute asthma: the Italian Pediatric Network experience.
CONCLUSION: The pediatric network has become an excellent system of monitoring of the clinical management of asthmatic children, highlighting strengths and weaknesses on which to focus actions of improvement. PMID: 27852427 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - November 19, 2016 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Effect of Inhaled Corticosteroids in Steroid-Naive COPD Effect of Inhaled Corticosteroids in Steroid-Naive COPD
Explore the impact of inhaled corticosteroids on blood eosinophil levels among COPD patients who have not previously received steroid therapy.BMJ Open Respiratory Research
Source: Medscape Allergy Headlines - November 17, 2016 Category: Allergy & Immunology Tags: Pulmonary Medicine Journal Article Source Type: news

Can liquorice make steroids more palatable in multiple sclerosis?
Conclusion We have shown that administration of liquorice prior to steroid therapy reduces the severity of the metallic taste by half and was beneficial in over 90% of patients.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Low, S., Chataway, J. Tags: Immunology (including allergy), Multiple sclerosis ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Intracerebral haemorrhage in normotensive patient with probable neurosaroidosis
Conclusion Vasculopathy in neurosarcoidosis results from granulomatous destruction of vessel walls, perivascular inflammation and/or steroid-induced collagen fragility. This case highlights an under-recognised and serious complication that may occur as a result. Aggressive disease suppression via immunomodulatory treatment may help minimise the risk of haemorrhagic events.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Mirza, F., Das, J., Chauhan, V., Cooper, P., Pace, A. Tags: Immunology (including allergy), Neuroimaging, Radiology, Vascularitis, Radiology (diagnostics) ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research