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Total 83 results found since Jan 2013.

Advances in Sinus Surgery for Nasal Polyps
CONCLUSION: Surgical intervention remains a mainstay of therapy for CRSwNP. Newer techniques revolve around improving access for topical steroid therapy.PMID:36848271 | DOI:10.1177/19458924221147783
Source: American Journal of Rhinology and Allergy - February 27, 2023 Category: ENT & OMF Authors: T Graham Norwood Jessica W Grayson Bradford A Woodworth Source Type: research

State of the Art Medical Management of Nasal Polyps
CONCLUSIONS: Topical steroid therapy is clearly effective for CRSwNP, and recent studies demonstrate the safety and efficacy of high-dose nasal steroid rinses. Alternate delivery methods for local steroids may be useful for patients who are not responding to or who are noncompliant with conventional intranasal corticosteroid sprays and rinses. Future studies are needed to clarify if oral or topical antibiotics, oral anti-leukotrienes, or other novel therapies are significantly effective in decreasing symptoms and improving the quality of life in patients with CRSwNP.PMID:36848283 | DOI:10.1177/19458924221145256
Source: American Journal of Rhinology and Allergy - February 27, 2023 Category: ENT & OMF Authors: Kelly L Staricha Hawa M Ali Janalee K Stokken Source Type: research

Lymphocytic Esophagitis: A Case Series of Esophageal Disease with Increasing Frequency
CONCLUSIONS: LE seems to be a benign but disturbing clinical problem and should be remembered in elderly females complaining of dysphagia or refractory reflux symptoms. It has similar endoscopic findings of eosinophilic esophagitis with rings and esophagitis. Smoking and hiatal hernia are common risk factors. The majority of LE patients can respond to proton pump inhibitor (PPI) therapy. Endoscopic dilations and steroid therapy should be considered for PPI nonresponder LE patients.PMID:36718059 | DOI:10.2174/2772270817666230130093341
Source: Adv Data - January 31, 2023 Category: Epidemiology Authors: Mohamad Yousef Harleen Chela Hamza Ertugrul Abdulmajeed Albarrak Omer Basar Syed Pasha Yousef Mousa Alhareth Al Juboori Shellaine Frazier Veysel Tahan Ebubekir Daglilar Source Type: research

Higher BMI May Dampen Steroid Response in EoE Higher BMI May Dampen Steroid Response in EoE
Body weight has emerged as a potential clinical predictor of reduced symptomatic, endoscopic, and histologic response to topical steroid therapy in patients with eosinophilic esophagitis.Medscape Medical News
Source: Medscape Allergy Headlines - December 5, 2022 Category: Allergy & Immunology Tags: Gastroenterology News Source Type: news

Novel Steroid Therapy May Counter Ataxia Telangiectasia Novel Steroid Therapy May Counter Ataxia Telangiectasia
A novel therapy for ataxia telangiectasia that delivers dexamethasone sodium phosphate through red blood cells is both ' promising and impressive ' in a new phase 3 trial, experts say.Medscape Medical News
Source: Medscape Allergy Headlines - April 8, 2022 Category: Allergy & Immunology Tags: Neurology & Neurosurgery News Source Type: news

Mid-term outcomes of mastoid obliteration with biological hydroxyapatite versus bioglass: a radiological and clinical study
ConclusionPost-operative CT scan of mastoid obliteration seems reliable in assessment of biomaterial graft ’s mid-term feasibility and stability: BHA seems to provide a more optimal osseointegration versus BG with no significant differences in graft resorption and clinical tolerance.
Source: European Archives of Oto-Rhino-Laryngology - January 17, 2022 Category: ENT & OMF Source Type: research

Late Breaking Abstract - Steroid resistance in obese asthmatic patients: a potential role of obesity-related systemic oxidative stress
Conclusions: Systemic oxidative stress caused by enlarged adipose tissue might involve steroid resistance in obese asthmatic patients.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: To, M., Honda, N., Kano, I., Haruki, K., To, Y. Tags: Allergy and immunology Source Type: research

Collagenous colitis in a child induced by chronic respiratory allergy: A case report
Conclusion: CC in children is rare, and childhood CC induced by a respiratory allergic reaction has not been previously reported. Therefore, this is a special case of CC in a patient who was cured with anti-allergy treatments and desensitization instead of steroid therapy.
Source: Medicine - August 28, 2020 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Ocular allergic contact dermatitis from topical drugs
Purpose of review Ocular allergic contact dermatitis is a common yet challenging and frequently misdiagnosed condition. Inappropriate or delayed treatment can contribute to a variety of clinical symptoms such as tearing and itching with signs such as ptosis and cicatricial ectropion, resulting in deterioration of disease, for which the topical medication was originally prescribed to resolve. Recent findings Understanding previously unrecognized pathogenic mechanisms involving ocular contact dermatitis has driven new approaches to control the inflammatory process by neutralizing inflammatory mediators and their recepto...
Source: Current Opinion in Allergy and Clinical Immunology - August 27, 2020 Category: Allergy & Immunology Tags: EYE ALLERGY: Edited by Leonard Bielory and Abraham Solomon Source Type: research

Asthma Patients: Stay on Steroids in Face of COVID-19, Say Experts Asthma Patients: Stay on Steroids in Face of COVID-19, Say Experts
Patients with asthma should stay on their preventive steroid therapy, both to protect against infection with COVID-19 as well as if they succumb to the virus, say experts in respiratory medicine.Medscape Medical News
Source: Medscape Allergy Headlines - March 20, 2020 Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news

Unexpected effects of systemic steroids on the CRSwNP proteome: is protein upregulation more important than inhibition?
ConclusionProteomic analysis of differentially expressed proteins in CRSwNP demonstrates that systemic steroids cause almost uniform upregulation of transcriptionally decreased proteins, whereas the effects of steroids on transcriptionally increased proteins are more heterogeneous. Thus, proteomic analysis may be an effective tool to understand specific therapeutic benefits of steroid use in polyp disease and to create more targeted treatments.
Source: International Forum of Allergy and Rhinology - February 5, 2020 Category: Allergy & Immunology Authors: Alan D. Workman, Michelle M. Miyake, Angela L. Nocera, Sarina K. Mueller, Kristen Finn, Hasan H. Otu, Towia A. Libermann, Benjamin S. Bleier Tags: ORIGINAL ARTICLE Source Type: research

Th2 inflammatory responses in the development of nasal polyps and chronic rhinosinusitis
Purpose of review Pathogenesis of nasal polyp has been largely studied based on innate and adaptive immunity of sinonasal mucosa. So far, various factors have been identified that trigger an inflammatory response in the pathogenesis of nasal polyps. In this review, we summarized recently updated information in the understanding of mechanisms in the development of chronic rhinosinusitis with nasal polyp (CRSwNP) focusing on Th2 inflammation. Recent findings Endotype of CRSwNP presented mainly Th2-skewed inflammation, and it has been associated with refractoriness and comorbidities. Staphylococcus aureus can drive Th2 i...
Source: Current Opinion in Allergy and Clinical Immunology - January 3, 2020 Category: Allergy & Immunology Tags: RHINITIS, SINUSITIS AND UPPER AIRWAY DISEASE: Edited by Ruby Pawankar and David P. Skoner Source Type: research

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